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140篇 您的检索式:作者名="CHRISTINA P"
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1Double versus single homologous intrauterine insemination for male factor infertility: a systematic review and meta-analysis显示文摘男因素不孕影响 30 % -50%世界范围的不肥沃的夫妇,并且对这些病人的最佳的管理有增加的利息。在比较双、单个的子宫内的授精(IUI ) 的研究,向更高的怀孕的一个趋势评价在结合男因素不孕被观察。因此,我们开始执行元分析与男搭挡的精子检验双对单个的 IUI 的优势在结合男因素不孕。机会比率(或) 95 %信心间隔(CI ) 为怀孕率被计算。结果被根据结果的异质使用 Mantel-Haesel 或 DerSimonian 地主模型分析。总的来说,包含 1125 个 IUI 周期的五试用在元分析被包括。与有单个 IUI 的一个周期相比在有双 IUI 的一个周期以后的怀孕有双重的增加(或:2.0;95 %CI:1.07-3.75;P< 0.03 ) 。不过,这结果主要被归因于大试用的存在那象几乎 50 % 加权;在全面分析。敏感分析,排除这大试用,在两倍 IUI 周期之中向更高的怀孕率揭示了仅仅一个趋势(或:1.58;95 %CI:0.59-4.21 ) ,但是没有统计意义(P=0.20 ) 。我们系统的评论热点关于两倍 IUI 在的使用的可得到的证据结合男因素不孕碎片、弱。尽管可以向更高的怀孕率有一个趋势,当 IUI 的数字每周期被增加时,进一步大、设计得好的使随机化的审判被需要提供稳固的证据指导当前的临床的实践。Apostolos Zavos Alexandros Daoonte Antonios Garas Christina Verykouki Evangelos Papanikolao~ Georgios Anifandis Nikolaos P Polyzos 2013Asian Journal of Andrology2013,15,4:9
2Presentation and surgical management of xanthogranulomatous cholecystitis显示文摘Background:Xanthogranulomatous cholecystitis(XGC)is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and most of the times requires surgical management.In addition,distinguishing XGC from gallbladder cancer preoperatively is still a challenge.The aim of the present systematic review was to outline the clinical presentation and surgical approach of XGC.Data sources:The present systematic review was designed using the PRISMA and AMSTAR guidelines.We searched MEDLINE,Scopus,Clinicaltrials.gov,EMBASE,Cochrane Central Register of Controlled Trials(CENTRAL)and Google Scholar databases from inception until June 2020.Results:The laparoscopic cholecystectomy rate(34%)was almost equal to the open cholecystectomy rate(47%)for XGC.An important conversion rate(35%)was observed as well.The XGC cases treated by surgery were associated with low mortality(0.3%),limited intraoperative blood loss(58-270 m L),low complication rates(2%–6%),along with extended operative time(82.6–120 minutes for laparoscopic and 59.6–240 minutes for open cholecystectomy)and hospital stay(3–9 days after laparoscopic and 8.3–18 days after open cholecystectomy).Intraoperative findings during cholecystectomies for XGC included empyema or Mirizzi syndrome.In addition,complex surgical procedures,like wedge hepatic resections and bile duct excision were required during operations for XGC.Conclusions:XGC seemed to be a rare,benign inflammatory disease that presents similar features as gallbladder cancer.The mortality and complication rates of XGC were low,despite the complex surgical procedures that might be required in some cases.Maximos Frountzas Dimitrios Schizas Efstathia Liatsou Konstantinos P Economopoulos Christina Nikolaou Konstantinos G Apostolou Konstantinos G Toutouzas Evangelos Felekouras 2021Hepatobiliary & Pancreatic Diseases International2021,20,2:4
3Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS.Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight 2010Cellular & Molecular Immunology2010,7,3:3
4Is deep vein thrombosis a good proxy for pulmonary embolus显示文摘Javad P Christina L J Orhan B 2010The Journal of Arthroplasty2010,15,6:1
5An analytic expression for the field dependence of Zernike polynomialrotationally symmetric optical systems显示文摘Robert W Gray Christina Dunn Kevin P Thompson 2012Opt Express2012,20,16:1
6Studies on the antilithic effect of Rotula aqucttica lout in male Wistar rats 显示文摘Christina A J Priyaomole M Moorthy P 2002Methods Find Exp Clin Pharmacol2002,24,4:1
7Epigallocatechin gallate, the main polyphenoL in green tea, binds to the T-cell receptor, CD4: Potential for HIV-ltherapy显示文摘Williamson M P McCormick T G Nance Christina L 2006Journal of Allergy and ClinicaL Immunology2006,8,6:1
8Using human perceptual categories for content-based retrieval from a medical image database显示文摘Chi R S Christina P Avinash C K 2002Computer Vision and Image Understanding2002,88,3:1
9Use of WL medium to profile native flora fermentations显示文摘CHRISTINA L P JAMES A B TAMMI L O 2001American Journal of Enology and Viticulture2001,52,3:1
10Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and clAP1 in situ显示文摘Christina R Mihnea V Michael P 2002Biol Chem2002,277,5:1
11Lay- er-by-layer engineered capsules and their applications 显示文摘ANGUS P R J CHRISTINA C ALEXANDRA S A 2006Curr Opin Colloidln2006,11,4:1
12Physiology of resistant Deinococcus geothermalis bacterium aerobically cultivated in low-Manganese medium显示文摘Christina L Minna P J?rg B Peter N Mirja S S 2012Journal of Bacteriology2012,194,6:1
13Long-Term Therapy with Continuous Positive Airway Pressure in Obstructive Sleep Apnea: Adherence, Side Effects and Predictors of Withdrawal A 'Real-Life' Study显示文摘Wolfgang G Letizia P Christina P 2011Respiration2011,82,2:1
14Caspase 3 activation is essential for efficient influenza virus propagation显示文摘Walter J w Oliver P Christina E 2003The EMBO Journal2003,22,11:1
15Job burnout显示文摘Maslach Christina Wilmar B Schaufeli Michael P Leiter 2001Annual Review of Psychology2001,52,01:1
16Mitochondrial loss,dysfunction and altered dynamics in Huntington's disease 显示文摘Kim Jinho Moody Jennifer P Edgerly Christina K 2010Hum Mol Genet2010,19,20:1
17Understanding zinc (Ⅱ) chelation with quercetin and luteolin: a combined NMR and theoretical study显示文摘ALEXANDRA P GLORIA M CHRISTINA L 2015J Phys Chem B2015,119,1:1
18γδ T cells:an important source of IL-17 Christina显示文摘Christina L Roark P L Simonian A P 2008Curr Opin Immunol2008,20,3:1
19The development of re- sponse selection accuracy in a football linebacker using video train- ing 显示文摘Christina R W Barresi J V Shaffner P 1990The Sport Psychologist1990,,4:1
20Characterization of a thermophilic sulfur oxidizing enrichment culture dominated by a Sulfolobus sp. obtained from an underground hot spring for use in extreme bioleaching conditions显示文摘Virpi L. A. Salo-Zieman Tarja Sivonen Jason J. Plumb Christina M. Haddad Katja Laukkanen P?ivi H. M. Kinnunen Anna H. Kaksonen Peter D. Franzmann Jaakko A. Puhakka 2006Journal of Industrial Microbiology & Biotechnology2006,,12:1
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