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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018，61，6： | 39 |
| 2 | The Arabidopsis P450 protein CYP82C2 modulates jasmonateinduced root growth inhibition, defense gene expression and indole glucosinolate biosynthesis显示文摘Jasmonic 酸(JA ) 是对草食动物和一些微生物引起的病原体调整大量植物防卫回答的一个丰满的导出酸的发信号分子。分子的基因研究证实了 JA 也在植物开发的几个方面执行一个关键角色。这里,我们描述 Arabidopsis 变异的 jasmonic acid-hypersensitive1-1 (jah1-1 ) 的描述,它在 JA 回答的几个方面是有缺点的。尽管异种在根生长抑制展出增加的敏感到 JA,它显示出 JA 可诱导的防卫基因和减少的抵抗的减少的表示到 necrotrophic 真菌 Botrytis cinerea。基因克隆研究显示这些缺点被一个变化在细胞色素 P450 蛋白质 CYP82C2 引起。我们提供证明的证据到 B 的 jah1-1 异种的损害抵抗。cinerea 被导致 JA 的防卫基因的减少的表示伴随并且减少了导致 JA 的吲哚 glucosinolates (IG ) 的累积。相反地,提高的抵抗到 B。在 CYP82C2-overexpressing 植物的 cinerea 被导致 JA 的防卫基因的增加的表示伴随并且提高了导致 JA 的 IG 的层次。我们证明 CYP82C2 影响 IG biosynthetic 先锋的导致 JA 的累积色氨酸(Trp ) ,然而并非导致 JA 的 IAA 或导致病原体的 camalexin。一起,我们 CYP82C2 可以在导出 Trp 的第二等的代谢物的新陈代谢扮演在下面的一个假设在 JA 在哪个铺平调节的结果支持被提高。jah1-1 异种应该因此在向理解位于调停 JA 的微分回答的复杂性下面的机制的未来研究是重要的,它是重要的让植物使他们的生长适应千变万化环境。 | Fang Liu Hongling Jiang Songqing Ye Wen-Ping Chen Wenxing Liang Yingxiu Xu Bo Sun Jiaqiang Sun Qiaomei Wang Jerry D Cohen Chuanyou Li | 2010 | Cell Research2010，20，5： | 10 |
| 3 | Extracellular calcium elicits feedforward regulation of the roll-like receptor-triggered innate immune response显示文摘 | Songqing Tang Taoyong Chen Mingjin Yang Lei Wang Zhou Yu Bin Xie Cheng Qian Sheng Xu Nan Li Xuetao Cao Jianli Wang | 2017 | Cellular & Molecular Immunology2017，14，2： | 3 |
| 4 | A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice显示文摘 | He Songqing Atkinson Carl Qiao Fei Cianflone Katherine Chen Xiaoping Tomlinson Stephen | 2009 | Journal of Clinical Investigation2009，，8： | 2 |
| 5 | Multiple weighted estimates for commutators of multilinear fractional integral operators显示文摘Multilinear commutators and iterated commutators of multilinear fractional integral operators with BMO functions are studied. Both strong type and weak type endpoint weighted estimates involving the multiple weights for such operators are established and the weak type endpoint results are sharp in some senses. In particular, we extend the results given by Cruz-Uribe and Fiorenza in 2003 and 2007 to the multilinear setting. Moreover, we modify the weak type of endpoint weighted estimates and improve the strong type of weighted norm inequalities on the multilinear commutators given by Chen and Xue in 2010 and 2011. | CHEN SongQing WU HuoXiong | 2013 | Science China Mathematics2013，56，9： | 2 |
| 6 | Utilize cloud computing to support dust storm forecasting显示文摘The simulations and potential forecasting of dust storms are of significant interest to public health and environment sciences.Dust storms have interannual variabilities and are typical disruptive events.The computing platform for a dust storm forecasting operational system should support a disruptive fashion by scaling up to enable high-resolution forecasting and massive public access when dust storms come and scaling down when no dust storm events occur to save energy and costs.With the capability of providing a large,elastic,and virtualized pool of computational resources,cloud computing becomes a new and advantageous computing paradigm to resolve scientific problems traditionally requiring a large-scale and high-performance cluster.This paper examines the viability for cloud computing to support dust storm forecasting.Through a holistic study by systematically comparing cloud computing using Amazon EC2 to traditional high performance computing(HPC)cluster,we find that cloud computing is emerging as a credible solution for(1)supporting dust storm forecasting in spinning off a large group of computing resources in a few minutes to satisfy the disruptive computing requirements of dust storm forecasting,(2)performing high-resolution dust storm forecasting when required,(3)supporting concurrent computing requirements,(4)supporting real dust storm event forecasting for a large geographic domain by using recent dust storm event in Phoniex,05 July 2011 as example,and(5)reducing cost by maintaining low computing support when there is no dust storm events while invoking a large amount of computing resource to perform high-resolution forecasting and responding to large amount of concurrent public accesses. | Qunying Huang Chaowei Yang Karl Benedict Songqing Chen Abdelmounaam Rezgui Jibo Xie | 2013 | International Journal of Digital Earth2013，6，4： | 2 |
| 7 | A performance study of BitTorrent like peer-to-peer systems显示文摘 | Guo Lei Chen Songqing Xiao Zhen | 2007 | IEEE Journal on Selected Areas in Communications2007，25，1： | 1 |
| 8 | A performance study of bittorrent-like peer-to-peer systems 显示文摘 | Lei Guo Songqing Chen Zhen Xiao | 2007 | IEEE Journal on Selected Areas in Communications January2007，25，1： | 1 |
| 9 | Enhancing Data Authenticity and Integrity in P2P Systems显示文摘 | Zhang Xinwen Chen Songqing Ravi Sandhu | 2005 | IEEE Internet Computing2005，9，6： | 1 |
| 10 | Adaptive Memory Allocations in Clusters to Handle Unexpectedly Large Data-intensive Jobs显示文摘 | Xiao Li Chen Songqing Zhang Xiaodong | 2004 | IEEE Transactions on Parallel and Distributed Systems2004，15，7： | 1 |
| 11 | A performance study of BitTorrent-like peer-to-peer systems显示文摘 | Lei Guo Songqing Chen Zhen Xiao | 2007 | IEEE Journal on Selected Areas in Communications2007，25，1： | 1 |
| 12 | A Performance Study of BitTorrent-like Peer-to-Peer Systems 显示文摘 | Lei Guo Songqing Chen Zhen Xiao | 2007 | IEEE Journal on Selected Areas in Communications (S0733-8716)2007，25，1： | 1 |
| 13 | Segment-based Proxy Caching for Internet Streaming Media Delivery显示文摘 | Chen Songqing Wang Haining Zhang Xiaodong | 2005 | IEEE Multimedia2005，12，3： | 1 |
| 14 | Laser-induced voltage characteristics of Bi 2 Sr 2 Co 2 O y thin films on LaAlO 3 substrates显示文摘 | Shufang Wang Jinchun Cheng Xiaohui Zhao Songqing Zhao Liping He Mingjing Chen Wei Yu Jianglong Wang Guangsheng Fu | 2010 | Applied Surface Science2010，，1： | 1 |
| 15 | Enhancing Data Authenticity and Integrity in P2P Systems显示文摘 | Zhang Xinwen Chen Songqing Ravi Sandhu | 2005 | IEEE Internet Computing2005，9，6： | 1 |
| 16 | Segment-based Proxy Caching for Intemet Streaming Media Delivery显示文摘 | Chen Songqing Wang Haining Shen Bo | 2005 | IEEE Multimedia2005，12，3： | 1 |
| 17 | A Performance Study of BitTorrent like Peer to Peer Systems显示文摘 | GUO Lei CHEN Songqing XIAO Zhen | 2007 | IEEE Journal on Selected Areas in Commu nications2007，25，1： | 1 |
| 18 | Enhancing Data Authenticity and Integrity in P2P Systems显示文摘 | Zhang Xinwen Chen Songqing Sandhu R | 2005 | IEEE Internet Computing2005，9，6： | 1 |
| 19 | Measurements,analysis, and modeling of bittorrent-like systems显示文摘 | Guo Lei Chen Songqing Xiao Zhen | 2007 | IEEE Journal on Selected Areas in Communications2007，25，1： | 1 |
| 20 | A Performance Study of BitTorrent-like Peer-to-Peer Systems显示文摘 | Guo Lei Chen Songqing Xiao Zhen | 2007 | IEEE Journal on Selected Areas in Communications2007，25，1： | 1 |
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