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| 1 | The biological stress of early weaned piglets显示文摘Pigs experience biological stress such as physiological, environmental, and social challenges when weaned from the sow. The process of weaning is one of the most stressful events in the pig's life that can contribute to intestinal and immune system dysfunctions that result in reduced pig health, growth, and feed intake, particularly during the first week after weaning. Technological improvements in housing, nutrition, health, and management have been used to minimize some of the adverse effects of weaning stress, but a greater understanding of the biological impact of stress is needed to improve strategies to overcome weaning stress. The focus of this review paper is to briefly describe how the biological stress associated with weaning impacts intestinal morphology, structure, physiology, and intestinal immune responses that can impact subsequent production efficiencies such as growth, intake, morbidity, and mortality. | Joy M Campbell Joe D Crenshaw Javier Polo | 2013 | Journal of Animal Science and Biotechnology2013,4,2: | 83 |
| 2 | Coarctation of the aorta:Management from infancy to adulthood显示文摘Coarctation of the aorta is a relatively common form of congenital heart disease, with an estimated incidence of approximately 3 cases per 10000 births. Coarctation is a heterogeneous lesion which may present across all age ranges, with varying clinical symptoms, in isolation, or in association with other cardiac defects. The first surgical repair of aortic coarctation was described in 1944, and since that time, several other surgical techniques have been developed and modified. Additionally, transcatheter balloon angioplasty and endovascular stent placement offer less invasive approaches for the treatment of coarctation of the aorta for some patients. While overall morbidity and mortality rates are low for patients undergoing intervention for coarctation, both surgical and transcatheter interventions are not free from adverse outcomes. Therefore, patients must be followed closely over their lifetime for complications such as recoarctation, aortic aneurysm, persistent hypertension, and changes in any associated cardiac defects. Considerable effort has been expended investigating the utility and outcomes of various treatment approaches for aortic coarctation, which are heavily influenced by a patient's anatomy, size, age, and clinical course. Here we review indications for intervention, describe and compare surgical and transcatheter techniques for management of coarctation, and explore the associated outcomes in both children and adults. | Rachel D Torok Michael J Campbell Gregory A Fleming Kevin D Hill | 2015 | World Journal of Cardiology2015,7,11: | 27 |
| 3 | 中国双低油菜饼粕与加拿大卡诺拉粕品质特性的化学评价显示文摘系统地评价了 3个中国双低油菜与加拿大卡诺拉的商品饼粕与脱脂种籽的蛋白质、氨基酸、蔗糖、寡聚糖、饲粮总纤维和灰分等化学特性 ,并对饲粮总纤维的构成成分及加工的影响进行了研究。饲粮总纤维由非淀粉多糖、木质素和多酚、细胞壁蛋白质和矿物质组成。 3个中国双低菜粕的粗蛋白、蔗糖及必需氨基酸含量均接近或高于卡诺拉帕 ,但饲粮总纤维含量显著不同 ,尤其是蛋白质含量由于加工方式不同变异极大。在试验室条件下加工的脱脂种籽样品与相应的饼粕样品相比 ,蔗糖、赖氨酸和饲粮纤维含量变化显著。因此 。 | 彭健 B A Slominsk W Guenter L D Campbell 熊远著 | 2000 | 中国兽医学报2000,20,4: | 16 |
| 4 | 红细胞增多症/红细胞增多的诊断、检查和治疗指南显示文摘 | 潘玲丽 高举 McMullin M F Bareford D Campbell P | 2006 | 国际输血及血液学杂志2006,29,1: | 9 |
| 5 | 不同加工方式对“双低”菜粕品质的影响显示文摘对 2个不同加工方式生产的中国“双低”菜粕A和B以及 1个加拿大卡诺拉菜粕进行了体外消化和肉鸡饲养及代谢试验 ,以评价其营养价值。体外消化试验结果表明 ,卡诺拉菜粕、样品A和样品B的可消化蛋白质含量分别为 73 .6%、59.0 %和 51 .0 %(P <0 .0 1 ) ;2周的肉鸡生长试验表明 ,试验各期生长速度、采食量和饲料转化率差异显著 (P <0 .0 5)或极显著 (P <0 .0 1 ) ;代谢试验结果表明氮沉积率组间差异显著 (P <0 .0 5)。过热处理时 ,与中性洗涤纤维相连的蛋白质消化率降低 (P <0 .0 1 ) ,是导致氮沉积率低和肉鸡生长性能差的直接原因。试验结果也表明 ,过热处理或热处理不足 ,都对“双低”菜籽饼粕质量产生严重影响。 | 彭健 B A Slominski W Guenter L D Campbell 熊远著 | 2000 | 中国畜牧杂志2000,36,5: | 8 |
| 6 | 早期断奶仔猪的生物学应激显示文摘当仔猪断奶后离开其母猪时,会遭遇到生物学应激,如生理的、环境的和社会的挑战。断奶过程是猪一生中最具应激性的事件,会造成肠道和免疫系统的机能障碍,结果导致猪健康状况、生长性能和采食量的降低,特别是断奶后首周内。饲养系统、营养、健康和管理技术的改进已被用来将断奶应激的一些不利影响降至最小程度,但是更好地了解应激的生物学作用,为改进能够克服断奶应激的策略所需要的。本综述的重点,是简要地描述与断奶有关的生物学应激是如何通过影响肠道形态、结构、生理和肠道免疫反应,进而可能会影响生产效率,如生长、采食量、发病率和死亡率。 | 陈建康 Joy M Campbell Joe D Crenshaw Javier Polo | 2014 | 国外畜牧学(猪与禽)2014,0,S1: | 8 |
| 7 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997,,2: | 6 |
| 8 | The mechanical behavior of locking compression plates compared with dynamic compression plates in a cadaver radius model显示文摘 | Gardner MJ Brophy RH Campbell D | | 0,,9: | 2 |
| 9 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013,19,21: | 2 |
| 10 | Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs. | Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill | 2014 | World Journal of Cardiology2014,6,5: | 2 |
| 11 | Blind invasive diagnostic procedures in ventilatorassociated pneumonia 显示文摘 | Campbell G D | 2000 | Chest2000,117,42: | 2 |
| 12 | 药剂师处方改善社区居民血压的随机试验:Alberta改善高血压临床试验显示文摘高血压控制率高居不下。执业药师的临床作用不断扩大,其在改善社区高血压治疗方面可能有较大帮助。该研究旨在确定药剂师处方对社区居住患者血压控制的影响。方法:研究人员进行随机对照试验,通过Alberta省23个社区药店、医院或基层医疗小组,纳入血压高于目标血压的成年患者。 | 刘莉 叶鹏 Tsuyuki RT Houle SK Charrois TL Kolber MR Rosenthal MM Lewanczuk R Campbell NR Cooney D McAlister FA | 2015 | 中华高血压杂志2015,23,7: | 2 |
| 13 | Aspects of modeling of high voltage ferroelectric nonlinear ceramic capacitors 显示文摘 | CAMPBELL C K VANWYK J D HOLM M F K | 1992 | IEEE Trans Compon Hydirds Manuf Technol1992,15,2: | 2 |
| 14 | Relaxation effects in high-voltage barium titanate non-linear ceramic disk capacitors 显示文摘 | CAMPBELL C K VANWYK J D HOLM M F K | 1993 | IEEE Trans Compon Hydirds Manuf Technol1993,16,4: | 2 |
| 15 | Ceramics in Dentistry: Historical Roots and Current Perspectives显示文摘 | Kelly J R Nishimura I Campbell S D | 1996 | J Prosthet Dent1996,75,: | 1 |
| 16 | SH3 Domains: Molecular 'Velcro' 显示文摘 | Morton C J Campbell I D | 1994 | Curr Biol1994,4,7: | 1 |
| 17 | Paper birch and lodgepole pine root reinforcement in coarse-, medium-, and fine-,textured soils显示文摘 | Campbell K A Hawkins C D B | 2003 | Canadian Journal of Forest Research2003,33,: | 1 |
| 18 | Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut显示文摘 | BURNSTOCK G CAMPBELL G SATCHELL D | 1970 | Br J Pharmacol1970,40,4: | 1 |
| 19 | Whole grain amylose analysis in maize using near-infrared transmittance spectroscopy 显示文摘 | Campbell M R Brumm T J Glover D V | 1997 | Cereal Chemistry1997,74,3: | 1 |
| 20 | Developmental switches in chemokine response profiles during B cell differentiation and maturation显示文摘 | Campbell JJ Soler D | 2000 | J Exp Med2000,191,8: | 1 |