维普中文期刊产品整合服务
622篇 您的检索式:作者名="CALADO"
    题名 作者 年代 出处 被引量
1Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein显示文摘Li-Fan Lu To-Ha Thai Dinis Pedro Calado Ashutosh Chaudhry Masato Kubo Kentaro Tanaka Gabriel B. Loeb Hana Lee Akihiko Yoshimura Klaus Rajewsky Alexander Y. Rudensky 2009Immunity2009,,1:2
2CITED2 and the modulation of the hypoxic response in cancer显示文摘CITED2(CBP/p300-interacting transactivator with Glu/Asp-rich C-terminal domain,2)is a ubiquitously expressed protein exhibiting a high affinity for the CH1 domain of the transcriptional co-activators CBP/p300,for which it competes with hypoxia-inducible factors(HIFs).CITED2 is particularly efficient in the inhibition of HIF-1α-dependent transcription in different contexts,ranging from organ development and metabolic homeostasis to tissue regeneration and immunity,being also potentially involved in various other physiological processes.In addition,CITED2 plays an important role in inhibiting HIF in some diseases,including kidney and heart diseases and type 2-diabetes.In the particular case of cancer,CITED2 either functions by promoting or suppressing cancer development depending on the context and type of tumors.For instance,CITED2 overexpression promotes breast and prostate cancers,as well as acute myeloid leukemia,while its expression is downregulated to sustain colorectal cancer and hepatocellular carcinoma.In addition,the role of CITED2 in the maintenance of cancer stem cells reveals its potential as a target in non-small cell lung carcinoma and acute myeloid leukemia,for example.But besides the wide body of evidence linking both CITED2 and HIF signaling to carcinogenesis,little data is available regarding CITED2 role as a negative regulator of HIF-1αspecifically in cancer.Therefore,comprehensive studies exploring further the interactions of these two important mediators in cancer-specific models are sorely needed and this can potentially lead to the development of novel targeted therapies.Mónica T Fernandes Sofia M Calado Leonardo Mendes-Silva JoséBraganca 2020World Journal of Clinical Oncology2020,11,5:2
3Current concepts in the pathophysi-ology and treatment of aplastic anemia显示文摘 Calado RT Scheinberg P 2006Blood2006,108,8:1
4Regulation of the germinal center response by microRNA-155显示文摘THAI T H CALADO D P CASOLA S 2007Science2007,316,5824:1
5Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein显示文摘Lu LF Thai TH Calado DP 2009Immunity2009,30,1:1
6Foxp3-dependent mieroRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein显示文摘Lu LF Thai TH Calado DP 2009Immunity2009,30,1:1
7Gemini surfactant-protein interactions:effect of p H,temperature,and surfactant stereochemistry显示文摘Faustino C M Calado A R Garcia-Rio L 2009Biomacromolecules2009,10,:1
8Lymphoproliferative disease and autoimmunity in mice with increased microRNA17-92 expression in lymphocytes 显示文摘Xiao C Srinivasan L Calado DP 2008Nature Immunol2008,9,4:1
9Nuclear export of microRNA precursors显示文摘Lund El Giittinger S Calado Av 2004Science2004,303,5654:1
10Image retrieval using multiple evidence ranking 显示文摘COELHO T A S CALADO P P SOUZA L V 2004IEEE Trans on Knowledge and Data Engineering2004,16,4:1
11Lymphoprolif- erative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes 显示文摘Xiao C Srinivasan L Calado D P 2008Nat Immunol2008,9,4:1
12Current concepts in the pathophysiology and treatment of aplastic anemia显示文摘Young NS Calado RT Scheinberg P 0,,08:1
13High pressure-temperature effects on enzymatic activity:Naringin bioconversion显示文摘Vila-Real HJ Alfaia AJ Calado ART 0,,03:1
14Current concepts in the pathophysiology and treatment of aplastic ane- mia显示文摘YOUNG N S CALADO R T SCHEINBERG P 2006Blood2006,108,8:1
15Apla-stic anemia显示文摘YOUNG N S SCHEINBERG P CALADO R T 2008Curr Opin Hematol2008,15,:1
16DNA translocation through graphenenanopores 显示文摘Schneider G F Kowalczyk S W Calado V E 2010Nano Letters2010,10,8:1
17Synergy between PI3K signaling and myc in Burkitt lymphomagenesis 显示文摘Sander S Calado DP Srinivasan L 2012Cancer Cell2012,22,2:1
18Telomerase: not just for the elongation of telomeres显示文摘Calado R T Chen J C 2006BioEssays2006,28,2:1
19Nuclear export of microRNA precursors显示文摘 Guttinger S Calado A 2004Science2004,303,5654:1
20Premature rupture of membranes at 20 weeks:report of a successful outcome after transcervical application of fibrin glue显示文摘Calado E Ayres-de-Campos D 2007Fetal Diagn Ther2007,22,1:1
返回顶部 每页显示:
共32页 首页 上一页 第1页 下一页 末页 /32 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费