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| 1 | Tectonic Evolution of the Meso-Tethys in the Western Segment of Bangonghu-Nujiang Suture Zone: Insights from Geochemistry and Geochronology of the Lagkor Tso Ophiolite显示文摘The subduction of the Bangonghu-Nujiang Meso-Tethys and the collision between the Lhasa and Qiangtang blocks were important events in the growth of the Tibetan crust. However,the timing of collision initiation and closure timing,as well as nature and structure of the Bangonghu ocean basin,are still poorly constrained. The Lagkor Tso ophiolite,located in the south of Gerze County,Tibet,is one of the most completed ophiolites preserved in the southern side of the BangonghuNujiang suture zone. This study discussed the tectonic evolution of the Bangonghu-Nujiang suture zone as revealed by the Lagkor Tso ophiolite investigated by field investigations,petrology,geochemistry,geochronology and tectonic analysis methods. We present new LA-ICP-MS zircon U-Pb and 39Ar/40 Ar ages for the Lagkor Tso ophiolite,in addition to geochemical and platinum-group element(PGE) data presented for the Lagkor Tso ophiolite in Tibet. It is suggested that the ancient Lagkor Tso oceanic basin split in Middle Jurassic(161.2 ± 2.7 Ma – 165.4 ± 3.5 Ma),and experienced a second tectonic emplacement during the Early Cretaceous(137.90 ± 6.39 Ma). The Lagkor Tso ophiolite likely developed in an independent suture zone. The Bangonghu-Nujiang ocean subducted southwards,and the dehydration of the subducting oceanic crust materials caused partial melting of the continental mantle wedge,which formed the second-order expanding center of the obduction dish. This led to inter-arc expansion,followed by the formation of inter-arc and back-arc basins with island arc features,which are represented by ophiolites around the Shiquanhe-Lagkor Tso-Yongzhu region. The tectonic environment presently can be considered to be similar to that of the current Western Pacific,in which a large number of island arc-ocean basin systems are developed. | YUAN Yajuan YIN Zhengxin LIU Weiliang HUANG Qiangtai LI Jianfeng LIU Hongfei WAN Zhifeng CAI Zhourong XIA Bin | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 17 |
| 2 | Comparative biomechanical study of reversed less invasive stabilization system and proximal femoral nail antirotation for unstable intertrochanteric fractures显示文摘 | Chen Ying Liu Shouyao Lin Peng Wang Yunting Wang Jinhui Tao Jianfeng Cai Rongrong | 2014 | Chinese Medical Journal2014，，23： | 13 |
| 3 | Abundance and biomass of heterotrophic microbes in the Kongsfjorden, Svalbard显示文摘Abundance and biomass of heterotrophic microbes were investigated using epifluorescense microscopy in August 2004 along a transect in the Kongsfjorden, a glacial fjord in the high arctic, located in the north-western part of Svalbard. A bacterial abundance was low at outer fjord stations (on average 2.29×108 ind./dm3) and was higher at inner fjord stations (on average 3.52×108 ind./dm3).The biomass of bacteria ranged from 3.69 to 8.01 mg/m3.The abundance of bacteria was low at the surface of water(0 m), whereas the higher abundances often occurred at depths of 30~50 m.The abundance of heterotrophic flagellates varied from 2.785 to 8.891×104 ind./dm3.The assemblage was numerically dominated by less than 5 μm heterotrophic flagellates (78.67%~94.80%).The biomass of heterotrophic flagellates varied from 0.37 to 2.30 mg/m3.The mean biomass distribution for all stations was 4.91% for less than 5 μm heterotrophic flagellates, 86.74% for 6~20 μm flagellates and 8.35% for greater than 20 μm sized flagellates.The low biomass of heterotrophic flagellates often occurred at the surface of water(0 m),while the maximum value of biomass occurred at different depths. The biomass of total heterotrophic microbial community ranged from 4.20 to 10.03 mg/m3.The mean biomass distribution for all stations was 82.58% for bacteria, 15.77% for flagellates and 1.66% for ciliates. | JIANG Xiaodong HE Jianfeng CAI Minghong | 2005 | Acta Oceanologica Sinica2005，24，6： | 6 |
| 4 | Therapeutic effect of electroacupuncture,massage,and blocking therapy on external humeral epicondylitis显示文摘OBJECTIVE:To compare two therapeutic methods:electroacupuncture + massage + blocking therapy,and blocking therapy alone in the treatment of external humeral epicondylitis.METHODS:Eighty-six patients were randomized into two groups with 43 in each. The treatment group received electroacupuncture + massage +blocking therapy, while the control group received blocking therapy only. A course of electroacupuncture treatment included therapy once a day for 10days. There were 10 treatments in a massage course and massage was given once a day, with a1-week interval given before the next course. A course of blocking treatment included therapy once a week, for twototaltreatments,andgenerallyno more than three times. The therapeutic effects were evaluated with the visual analog scale(VAS),grip strength index(GSI) score, and Mayo elbow performance score(MEPS) before treatment and at0, 6, 12, and 24 months after treatment to observe thetotaleffectiverate.RESULTS: In the treatment and control groups before treatment and at 0, 6, 12, and 24 months after treatment, the VAS scores were: 6.5±1.9 and 6.4±1.6; 4.6±1.3 and 4.6±1.7; 4.8±1.3 and 4.8±1.2; 4.6±1.2 and 6.6±1.6; and 6.5±1.6 and 6.5±1.3, respectively. The GSI scores were 63±8 and 63±8; 84±6and82±7;82±7and82±6;84±6and62±8;and64±6 and 64±7, respectively.The MEPS of both groups were65±7and66±8;85±6and84±7;84±5and84±7;80±7and66±6;and65±6and65±7,respectively.The total effective rates of the treatment and control groups at 0, 6, 12, and 24 months after treatment were 87.5% and 85.0%; 85.0% and 82.5%;80.0% and 12.5%; and 2.5% and 5.0%, respectively.Compared with the treatment group, the control group had greater joint function, better the rapeutic effect, and lower pain intensity(P<0.01), indicating a high recurrence rate in the 12th month after treatment.There were no differences inVAS, GSI, or MEPS at 0, 6, and 24 months after treatment(P>0.05)betweenthetwogroups.CONCLUSION: We found that both methods were effective for external humeral epicondylitis. After 6months of treatment,the effects were good in both groups. However, in the 12th month, the control group had a relatively severe relapse. After 24months, both groups relapsed. The effect of electroacupuncture, massage, and blocking therapy used in combination lasted longer, delaying the recurrence of the disease. | Xinjian Li Kun Zhou Enming Zhang Zhen xiQi Weiqing Sun Liangfu Xu Jianfeng Xu Youzhi Cai Ronghui Wang | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 6 |
| 5 | Germination and early seedling growth of Pinus densata Mast.provenances显示文摘We studied seed germination and early seedling growth of Pinus densata to explore the range of variability within the species and to inform afforestation practices.Phenotypes were evaluated at a forest tree nursery under conditions that support Pinus yunnanensis, one of the presumed parental species of P. densata. Seeds were collected from 20 open-pollinated trees within each of eight autochthonous populations representing the natural distribution of P. densata in China to assess variation in germination traits and early seedling growth, and to examine the relationships among these traits. Results showed that seeds from all populations germinated and seedlings established successfully. There were significant differences among populations in 13 of 14 traits evaluated. Seed germination and early seedling growth were strongly related to seed size and seed weight. Bigger seeds germinated earlier and faster than small seeds, and seedling size was positively correlated with seed size. Some germination traits were strongly and significantly correlated with climatic variables associated with the provenance of the studied populations. Based on these observations, we conclude there were large, significant, and biologically important differences among P. densata populations in seed germination and seedling growth traits. The observed variability probably reflects a high degree of adaptive differentiation among populations that is likely to be relevant for future afforestation. | Yulan Xu Nianhui Cai Bin He Ruili Zhang Wei Zhao Jianfeng Mao Anan Duan Yue Li Keith Woeste | 2016 | Journal of Forestry Research2016，27，2： | 5 |
| 6 | Effect of Silicon on Arsenic Concentration and Speciation in Different Rice Tissues显示文摘Rice is a major source of inorganic arsenic(As) exposure for billions of people worldwide. Therefore, strategies to reduce As accumulation in rice should be adopted. Silicon(Si) application can effectively mitigate As accumulation in rice. In this study, a pot experiment was performed to investigate the effect of Si on As speciation and distribution in different rice tissues. The results showed that Si addition significantly increased As and Si concentrations in soil solution and Si concentration in iron plaque formed around rice root surface, whereas As in the iron plaque was significantly decreased. Total As concentrations in the stem, leaf, husk, and brown rice were remarkably decreased by 51.9%, 31.9%, 33.8%, and 24.1%, respectively, after Si addition, and inorganic As concentrations were reduced by 52.3%, 35.5%, 50.1%, and 20.1%, respectively. Moreover, both dimethylarsinic acid concentration and percentage in rice grain were significantly elevated by Si application. Therefore, Si application is promising as a way to mitigate inorganic As accumulation in rice and to reduce consumer health risk. | LI Gang ZHENG Maozhong TANG Jianfeng SHIM Hojae CAI Chao | 2018 | Pedosphere2018，28，3： | 5 |
| 7 | Geochemistry,Geochronology,Sr-Nd Isotopic Compositions of Jiang Tso Ophiolite in the Middle Segment of the Bangong- Nujiang Suture Zone and Their Geological Significance显示文摘The Jiang Tso ophiolite,situated in the middle segment of the Bangong- Nujiang Suture Zone,is a part of the easternmost Qieli Lake ophiolite subzone and is close to the south of Pung Lake ophiolite. The rock association of Jiang Tso ophiolite is relatively complete and is mainly composed of metamorphic peridotite,gabbro and diabase. Comparing with N-MORB,the ophiolite is high in Mg and low in Ti,K,Na,P,and is depleted in Nb,Ta,Hf,Th and enriched in Rb,Sr and Ba. Geochemical characteristics of the Jiang Tso ophiolite indicate it is of a supra-subduction zone type formed in the spreading ridge of back arc basin. The SHRIMP U-Pb dating of zircons from the gabbro yielded a weighted average age of 188.1±4.1 Ma(MSWD=1.4),indicating the Jiang Tso ophiolite was formed in the late stage of early Jurassic. The Sr,Nd isotopic compositions show that the Tethyan mantle domain is the depleted mantle(DM),with enriched mantle domain II(EM II). They have the same Sr,Nd isotopic composition with the India Ocean MORB type. | HUANG Qiangtai LI Jianfeng CAI Zhourong XIA Lianze YUAN Yajuan LIU Huichuan XIA Bin | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 4 |
| 8 | Long-term variability of the carbon balance in a large irrigated area along the lower Yellow River from 1984 to 2006显示文摘The irrigated areas in the northern region of China are important food production areas. Therefore, studies on the variability of the carbon balance in these agro-ecosystems are fundamental for the management of carbon sequestration. This paper simulated the long-term variability of the carbon balance in a typical irrigated area along the lower Yellow River from 1984 to 2006, using a process-based ecosystem model called the Simple Biosphere Model, version 2. The mean annual gross primary production (GPP), mean annual net assimilation rate (NAR), mean annual soil respiration (Rs ), and mean annual net ecosystem exchange (NEE) were 1733, 1642, 1304, and 338g C m-2 a-1 , respectively. A significant increasing trend in the seasonal total NAR during the wheat growing season, and a significant decreasing trend in the seasonal total NAR during the maize growing season were detected. However, no significant trend was found in the annual NAR, R s , and NEE. The average carbon sequestration was 1.93 Tg C a-1 when the grain harvest was not taken into account, and the carbon sequestration amount during the maize season was higher than that during the wheat season. However, the agro-ecosystem was a weak carbon source with a value of 0.23 Tg C a-1 , when the carbon in the grain was assumed emitted into the atmosphere. | LEI HuiMin YANG DaWen CAI JianFeng WANG FengJiao | 2013 | Science China Earth Sciences2013，56，4： | 4 |
| 9 | Spatial heterogeneity of a microbial community in Kongsfjorden,Svalbard during late summer 2006 and its relationship to biotic and abiotic factors显示文摘The 16S and 18S ribosomal ribonucleic acid genes of microbial organisms collected from the contrasting environments (temperature,salinity,silicate,phosphate and nitrate,p <0.05) of the inner and outer basins of Kongsfjorden (Spitsbergen,Arctic) were studied using polymerase chain reaction-denaturing gradient gel electrophoresis(DGGE) fingerprinting.Comparison of the microbial fingerprints and the physicochemical parameters revealed that molecular methodology exhibited a greater sensitivity.Sequences obtained from bacterial DGGE were affiliated with four main phylogenetic groups of bacteria:Proteobacteria(Alpha,Beta and Gamma),Bacteroidetes,Verrucomicrobia and Cyanobacteria.The relationships between the genotype distribution of these microbes and associated biotic/abiotic factors,revealed by canonical correspondence analysis,showed that Station 1 at 30 m (outer fjord) was grouped separately from the other sites.This difference could be a consequence of the thermocline and base of the euphotic layer at this depth where the Atlantic and Arctic-type waters overlapped. | GUO ChaoYing HE JianFeng ZHANG Fang CAI MingHong WANG GuiZhong | 2011 | Chinese Journal of Polar Science2011，22，1： | 3 |
| 10 | Flow cytometry investigation of picoplankton across latitudes and along the circum Antarctic Ocean显示文摘Using a flow cytometer (FCM) onboard the R/V Xuelong during the 24th Chinese Antarctic cruise, picoplankton community structure and biomass in the surface water were examined along the latitude and around the Antarctic Ocean. Salinity and temperature were automatically recorded and total Chl a was determined. Along the cruise, the abundance of Synechococcus, Prochlorococcus, pico-eukaryotes and heterotrophic bacteria ranged in 0.001-1.855 × 10 8 ind./L, 0.000-2.778 × 10 8 ind./L, 0.002-1.060 × 10 8 ind./L and 0.132-27.073 × 10 8 ind./L, respectively. Major oceanic distribution of Synechococcus and Prochlorococcus appeared between latitudes 30 N and 30 S. Prochlorococcus was mainly influenced by water temperature, water mass combination and freshwater inflow. Meanwhile, Synechococcus distribution was significantly associated with landing freshwater inflow. Pico-eukaryotes and heterotrophic bacteria were distributed all over the oceans, but with a relatively low abundance in the high latitudes of the Antarctic Ocean. Principal Component Analysis showed that at same latitude of Atlantic Ocean and Indian Ocean, picoplankton distribution and constitution were totally different, geographical location and different water masses combination would be main reasons. | LIN Ling HE Jianfeng ZHAO Yunlong ZHANG Fang CAI Minghong | 2012 | Acta Oceanologica Sinica2012，31，1： | 3 |
| 11 | Safety of endovascular therapy for symptomatic intracranial artery stenosis:a national prospective registry显示文摘Introduction The safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown.The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis(CRTICAS)was a prospective,multicentre,real-world registry designed to assess these outcomes and the impact of centre experience.Methods 1140 severe,symptomatic intracranial arterial stenosis(ICAS)patients treated with endovascular therapy were included from 26 centres,further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years:(1)high volume for≥25 cases/year;(2)moderate volume for 10–25 cases/year and(3)low volume for<10 cases/year.Results The rate of 30-day stroke,transient ischaemic attack or death was 9.7%(111),with 5.4%,21.1%and 9.7%in high-volume,moderate-volume and low-volume centres,respectively(p<0.05).Multivariable logistic regression confirmed high-volume centres had a significantly lower primary endpoint compared with moderate-volume centres(OR=0.187,95%CI:0.056 to 0.627;p≤0.0001),while moderate-volume and low-volume centres showed no significant difference(p=0.8456).Conclusion Compared with the preceding randomised controlled trials,this real-world,prospective,multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS.Non-uniform utilisation in endovascular technology,institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. | Yabing Wang Tao Wang Adam Andrew Dmytriw Kun Yang Liqun Jiao Huaizhang Shi Jie Lu Tianxiao Li Yujie Huang Zhenwei Zhao Wei Wu Jieqing Wan Qinjian Sun Bo Hong Yongli Li Liyong Zhang Jianfeng Chu Qiong Cheng Yiling Cai Pengfei Wang Qi Luo Hua Yang Baijing Dong Yang Zhang Jun Zhao Zuoquan Chen Wei Li Xiaoxin Bai Weiwen He Xueli Cai Maimai Ti Osama O Zaidat | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 12 | Initial Rifting Process and Dynamics Mechanism of Huaguang Sag: Evidence from a Numerical Modeling Method显示文摘Huaguang Sag is located in the deep seawater area of Qiongdongnan Basin, and its tectonic position belongs to the intersection of NE-trending, SN-trending and NW-trending tectonic systems in the continental margin of the Northwest South China Sea. To investigate the initial rifting process and further more the dynamics mechanism of Huaguang Sag, this paper sets up the structure model of basement which mainly makes up with several depression-controlling faults, and simulates the initial rifting process of Huaguang Sag by the FLAC software. The simulation results show that only affected by the S-N trending extensional stress, the rifting center appears in northern boundary basement faults(two NEE-trending and NWW-trending faults) of Huaguang Sag while does not take place at the NNE-trending and NE-trending basement fault zone in the middle sag, and doesn't match the current pattern that the basement fault plays a main role in controlling the sediment. In the other case, affected by the S-N trending and E-W trending extensional stress at the same time, the areas of the northern boundary faults zone and internal NNE-trending basement faults zone come to be rifting center quickly, the sedimentary is controlled by the main basement faults to different degrees, and is consistent with the tectonic-sedimentary framework of Huaguang Sag which obtained by the data of geophysical interpretation. In combination with the analysis of regional tectonic background, the paper proposes that two remote tectonic effects occurred by the collision of India-Eurasian Plate: One remote effect was the rotational extrusion of Indo China Block, which led to form a series of NE-trending and NNE-trending basement faults, as well as the E-W trending tensile stress field in Huaguang Sag. The other remote effect was that the deep mantle material of South China Block flowed southward, which resulted in the S-N trending extensional rifting of the lithosphere in northern South China Sea, and finally formed a series of EW-trending and NEE-trending basement faults and the S-N trending tensile stress field in Huaguang Sag. Affected by the above tensile stress fields and the basement faults, the initial rifting occurred in E-W and nearly S-N directions along the pre-existed basement faults(the weak structural zones) in Huaguang Sag. | Zhourong Cai Bin Xia Baofeng Lü Weiqi Yao Jianfeng Li | 2015 | Journal of Earth Science2015，26，3： | 3 |
| 13 | Poly(α-L-lysine)-based nanomaterials for versatile biomedical applications:Current advances and perspectives显示文摘Poly(α-L-lysine)(PLL)is a class of water-soluble,cationic biopolymer composed ofα-L-lysine structural units.The previous decade witnessed tremendous progress in the synthesis and biomedical applications of PLL and its composites.PLL-based polymers and copolymers,till date,have been extensively explored in the contexts such as antibacterial agents,gene/drug/protein delivery systems,bio-sensing,bio-imaging,and tissue engineering.This review aims to summarize the recent advances in PLL-based nanomaterials in these biomedical fields over the last decade.The review first describes the synthesis of PLL and its derivatives,followed by the main text of their recent biomedical applications and translational studies.Finally,the challenges and perspectives of PLL-based nanomaterials in biomedical fields are addressed. | Maochao Zheng Miao Pan Wancong Zhang Huanchang Lin Shenlang Wu Chao Lu Shijie Tang Daojun Liu Jianfeng Cai | 2021 | Bioactive Materials2021，6，7： | 2 |
| 14 | Application of automatic surface inspection system in cold-rolled strip production显示文摘The detection and classification of real-time surface defects play an important role in automotive sheet inspection and production. In this paper,an automatic surface inspection system( ASIS) based on signal processing in Baosteel NO. 4 cold-rolled plant is briefly presented. We demonstrate that the strip surface defect properties such as image,type,pitch,and position can be accurately calculated and classified by the automatic surface inspection system.In the manufacturing of the high-quality cold-rolled strips,it is necessary that the real-time surface defects can be detected and transferred by the automatic surface inspection system combined with annealing lines and recoiling lines. | HE Jianfeng SU Yuan XIE Xianlong CAI Heng HE Chunlai | 2015 | Baosteel Technical Research2015，9，1： | 2 |
| 15 | Satellite Thermal Infrared Earthquake Precursor to the Wenchuan M_s 8.0 Earthquake in Sichuan,China,and its Analysis on Geo-dynamics显示文摘Based on an interpretation and study of the satellite remote-sensing images of FY-2C thermal infrared 1st wave band(10.3-11.3μm) designed in China,the authors found that there existed obvious and isolated satellite thermal infrared anomalies before the 5.12 Wenchuan M_s 8.0 Earthquake.These anomalies had the following characteristics:(1) The precursor appeared rather early:on March 18, 2008,i.e.,55 days before the earthquake,thermal infrared anomalies began to occur;(2) The anomalies experienced quite many and complex evolutionary stages:the satellite thermal infrared anomalies might be divided into five stages,whose manifestations were somewhat different from each other.The existence of so many anomaly stages was probably observed for the first time in numerous cases of satellite thermal infrared research on earthquakes;(3) Each stage lasted quite a long time,with the longest one spanning 13 days;(4) An evident geothermal anomaly gradient was distributed along the Longmen seismic fracture zone,and such a phenomenon might also be discovered for the first time in satellite thermal infrared earthquake research.This discovery is therefore of great guiding and instructive significance in the study of the earthquake occurrence itself and the trend of the postearthquake phenomena. | WEI Lejun GUO Jianfeng LIU Jianhua LU Zhenquan LI Haibing CAI Hui | 2009 | Acta Geologica Sinica(English Edition)2009，83，4： | 2 |
| 16 | Geochronology of the Dong Tso Ophiolite and the Tectonic Environment显示文摘The wedge shaped Dong Tso ophiolitic block is distributed near the transition point from the western to the middle sub–belt of the Bangong–Nujiang suture zone.The ophiolite is characterized by well–developed cumulate rocks that are mainly composed of cumulate and massive gabbros.In the cumulate gabbros,the adcumulate amphiboles are distributed extensively around the plagioclase and residual pyroxene grains;hence,the rocks are named adcumulate amphibole–gabbro.In this study,the formation age of the ophiolite has been estimated to be 166±4 million years(Ma)by the sensitive high–resolution ion microprobe(SHRIMP)II U–Pb isotopic analysis of the zircons from the adcumulate amphibole–gabbro;the40Ar/39Ar plateau age was estimated to be 148.19±1.53 Ma,which should represent the emplacement time of the ophiolite,by isotopic dating of the pure amphibole mineral from the amphibole–schist.Two different suits of volcanic lavas have been recognized in this work.The purple colored pillow basalts have high TiO2and P2O5contents,and are rich in light rare earth elements(LREEs),large–ion lithospheric elements(LILEs)and high–field–strength elements(HFSEs),the characteristics that are the typical of the oceanic island basalt(OIB).On the other hand,other massive basaltic andesites of celadon color are poor in MgO;rich in Fe2O3,LREEs,LILEs,and HFSEs;and especially characterized by negative Nb and Ta anomalies,the properties that establish the andesites as continental arc volcanic rocks.It is concluded that hotspots had developed in the old Dong Tso basin,the oceanic basin that had been developing from middle Jurassic(166 Ma)or even before and emplaced northward in late Jurassic(about 148 Ma). | LI Jianfeng XIA Bin XIA Lianze XU Lifeng LIU Weiliang CAI Zhourong YANG Zhiqing | 2013 | Acta Geologica Sinica(English Edition)2013，87，6： | 2 |
| 17 | Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers显示文摘Breast cancer is a heterogeneous disease.In particular,triple-negative breast cancer(TNBC)comprises various molecular subgroups with unclear identities and currently has few targeted treatment options.Our previous study identified protein C receptor(Procr)as a surface marker on mammary stem cells(MaSCs)located in the basal layer of the normal mammary gland.Given the possible connection of TNBC with basal layer stem cells,we conducted comparative analyses of Procr in breast cancers of mouse and human origin.In mouse mammary tumors,we showed that Procr+cells are enriched for cancer stem cells(CSCs)in Wnt1 basal-like tumors,but not in Brea basal-like tumors or PyVT luminal tumors.In human cancers,PROCR was robustly expressed in half of TNBC cases.Experiments with patient-derived xenografts(PDXs)revealed that PROCR marks CSCs in this discrete subgroup(referred to as PROCR+TNBC).Interfering with the function of PROCR using an inhibitory nanobody reduced the CSC numbers,arrested tumor growth and prevented rapid tumor recurrence.Our data suggest a key role of MaSC in breast tumorigenesis.Moreover,our work indicates that PROCR can be used as a biomarker to stratify TNBC into clinically relevant subgroups and may provide a novel targeted treatment strategy for this clinically important tumor subtype. | Daisong Wang Xin Hu Chunye Liu Yingying Jia Yiqin Bai Cheguo Cai Jingqiang Wang Lanyue Bai Ruikai Yang ChangDong Lin Yi-Rong Liu Shan Li Feng Qiao Ling Yao Li Chen Gaoxiang Ge Hai Jiang Dianfan Li Lin Li JianFeng Chen Zhi-Ming Shao Yi Arial Zeng | 2019 | Cell Research2019，29，10： | 2 |
| 18 | Endoscopic total parathyroidectomy and partial parathyroid tissue auto- transplantation for patients with secondary hyperparathyroid- ism : a new surgical approach 显示文摘 | Yueming Sun Huihua Cai Jianfeng Bai | 2009 | Word Surg2009，33，： | 1 |
| 19 | Primary Closure Following Laparoscopic Common Bile Duct Exploration Combined with Intraoperative Cholangiography and Choledochoscopy显示文摘 | Huihua Cai Donglin Sun Yueming Sun Jianfeng Bai Hanlin Zhao Yi Miao | 2012 | World Journal of Surgery2012，，1： | 1 |
| 20 | List edge and List Total coloring of planar graphs without 4- cycles 显示文摘 | HOU JIANFENG LIU GUIZHEN CAI JIANSHENG | 2006 | Theoretical Computer Science2006，369，： | 1 |
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