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1687篇 您的检索式:作者名="Butler M"
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1Current progress in use of adipose derived stem cells in peripheral nerve regeneration显示文摘Unlike central nervous system neurons; those in the peripheral nervous system have the potential for full regeneration after injury. Following injury, recovery is controlled by schwann cells which replicate and modulate the subsequent immune response. The level of nerve recovery is strongly linked to the severity of the initial injury despite the significant advancements in imaging and surgical techniques. Multiple experimental model shave been used with varying successes to augment the natural regenerative processes which occur following nerve injury. Stem cell therapy in peripheral nerve injury may be an important future intervention to improve the best attainable clinical results. In particular adipose derived stem cells(ADSCs) are multipotent mesenchymal stem cells similar to bone marrow derived stem cells, which are thought to have neurotrophic properties and the ability to differentiate into multiple lineages. They are ubiquitous within adipose tissue; they can form many structures resembling the mature adult peripheral nervous system. Following early in vitro work; multiple small and large animal in vivo models have been used in conjunction with conduits, autografts and allografts to successfully bridge the peripheral nerve gap. Some of the ADSC related neuroprotective and regenerative properties have been elucidated however much work remains before a model can be used successfully in human peripheral nerve injury(PNI). This review aims to provide a detailed overview of progress made in the use of ADSC in PNI, with discussion on the role of a tissue engineered approach for PNI repair.Shomari DL Zack-Williams Peter E Butler Deepak M Kalaskar 2015World Journal of Stem Cells2015,7,1:8
2Mechanical and cellular processes driving cervical myelopathy显示文摘Cervical myelopathy is a well-described clinical syndrome that may evolve from a combination of etiological mechanisms. It is traditionally classified by cervical spinal cord and/or nerve root compression which varies in severity and number of levels involved. The vast array of clinical manifestations of cervical myelopathy cannot fully be explained by the simple concept that a narrowed spinal canal causes compression of the cord, local tissue ischemia, injury and neurological impairment. Despite advances in surgical technology and treatment innovations, there are limited neuro-protective treatments for cervical myelopathy, which reflects an incomplete understanding of the pathophysiological processes involved in this disease. The aim of this review is to provide a comprehensive overview of the key pathophysiological processes at play in the development of cervical myelopathy.Roisin T Dolan Joseph S Butler John M O'Byrne Ashley R Poynton 2016World Journal of Orthopedics2016,7,1:5
3健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
4Control of stem cell fate by engineering their micro and nanoenvironment显示文摘Stem cells are capable of long-term self-renewal and differentiation into specialised cell types, making them an ideal candidate for a cell source for regenerative medicine. The control of stem cell fate has become a major area of interest in the field of regenerative medicine and therapeutic intervention. Conventional methods of chemically inducing stem cells into specific lineages is being challenged by the advances in biomaterial technology, with evidence highlighting that material properties are capable of driving stem cell fate. Materials are being designed to mimic the clues stem cells receive in their in vivo stem cell niche including topographical and chemical instructions. Nanotopographical clues that mimic the extracellular matrix(ECM) in vivo have shown to regulate stem cell differentiation. The delivery of ECM components on biomaterials in the form of short peptides sequences has also proved successful in directing stem cell lineage. Growth factors responsible for controlling stem cell fate in vivo have also been delivered via biomaterials to provide clues to determine stem cell differentiation. An alternative approach to guide stem cells fate is to provide genetic clues including delivering DNA plasmids and small interfering RNAs via scaffolds. This review, aims to provide an overview of the topographical, chemical and molecular clues that biomaterials can provide to guide stem cell fate. The promising features and challenges of such approaches will be highlighted, to provide directions for future advancements in this exciting area of stem cell translation for regenerative medicine.Michelle F Griffin Peter E Butler Alexander M Seifalian Deepak M Kalaskar 2015World Journal of Stem Cells2015,7,1:3
5CD133 expression is not restricted to stem cells, and both CD133^sup +^ and CD133^sup -^ metastatic colon cancer cells initiate tumors显示文摘Shmelkov Sergey V Butler Jason M Hooper Andrea T Hormigo Adilia Kushner Jared Milde Till Clair Ryan St Baljevic Muhamed White Ian Jin David K Chadburn Amy Murphy Andrew J Valenzuela David M Gale Nicholas W Thurston Gavin Yancopoulos George 2008Journal of Clinical Investigation2008,,:2
6Feasibility of percutaneous transluminal angioplasty for carotid artery stenosis显示文摘Brown M M Butler P Gibbs J 1990J Neurol Neurosurg Psychiatry1990,53,3:2
7文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
8An encephalomyocardit is virus epizootic in a baboon colony 显示文摘Hubbard G B Soike K F Butler T M 1992Lab Anim Sci1992,42,3:1
9An interlaboratory test of a procedure to assess soybean quality for soymilk and tofu production显示文摘 Fregeaul-Reid J A Butler M 2001Food Research International2001,34,:1
10Cold hardiness of bermudagrass and Paspalum vaginatum Sw 显示文摘Ibitayo O O Butler J D Bure M J 1981Hortscience1981,16,:1
11Evidence for a 15; 17translocation in every patient with acute promyelmytic leukemia显示文摘LARSON R A KONDO K VARDIMAN J W BUTLER A E GOLOMB H M ROWLEY J D 1984Am J Med1984,76,5:1
12Vanadium peroxide complexes显示文摘Butler A Clague M J Meister G E 1994Chem Rev1994,94,3:1
13Deletion of the FHIT gene in neoplastic and invasive cervical lesions is related to high-risk HPV infection but is independent of histopathological features显示文摘Butler D Collins C Mabruk M 2000J Pathol2000,192,:1
14Regulation of exoprotein expression in Staphylococcus aureus by a locus (sat) distinct from agr显示文摘Cheung A L Koomey J M Butler C A 1992Proc Natl Acad Sci1992,89,:1
15Scrapie injected murine neuroblastoma cells produce proteaseresistant prion proteins 显示文摘Butler D A Scott M R D Prusiner S B 1988J Virol1988,62,:1
16Corruption, Political Connections and Municipal Finance 显示文摘Butler A W Larry F Sandra M 2009Review of Finance2009,,22:1
17Design and Realization of GA-Optimized Wire Monopole and Matching Network With 20:1 Bandwidth显示文摘Shawn D Rogers Chalmers M Butler Anthony Q Martin 0,,03:1
18Ni- trite-driven anaerobic methane oxidation by oxygenic bacteria 显示文摘ETI'WIG K F BUTLER M K LE PASLIER D 2010Nature2010,464,7288:1
19Effects of human disturbances on the behavior of wintering ducks显示文摘PEASE M L ROSE R K BUTLER M J 2005Wildlife Society Bulletin2005,33,1:1
20Amplitude of low-frequency oscillations in schizophrenia: a resting state fM- RI study 显示文摘HOPTMAN M J ZUO XN BUTLER PD 2010Schizophr Res2010,117,1:1
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