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| 1 | Extramammary Paget's disease of the perianal region显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 2 | Characteristics of familial juvenile polyps expressing cyclooxygenase-2显示文摘 | Brazowski E Rosen P Misonzhnick-Bedny F | 2005 | Am J Gastroenterol2005，100，1： | 1 |
| 3 | Extramammary Paget's disease of the perianal region 显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 4 | Intraductal papillary mucinous neoplasm of the pancreas: Associated cancers, family history, genetic predisposition?显示文摘 | Nir Lubezky Menahem Ben-Haim Guy Lahat Sylvia Marmor Irit Solar Eli Brazowski Richard Nackache Joseph M. Klausner | 2012 | Surgery2012，，1： | 1 |
| 5 | Extramammary Pagers disease of the perianal region显示文摘 | Tulchiuaky H Zmora O Brazowski E | 2004 | Coloneetal Dis2004，6，3： | 1 |
| 6 | Flat colorectal neoplasia: identification, pathogenesis and clinical significance显示文摘 | P Rozen E Brazowski | 2003 | Digestive and Liver Disease2003，，3： | 1 |
| 7 | Extramammary Paget's disease of the perianal region 显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 8 | Galectin-3 expression in pouchitis in patients with ulcerative colitis who underwent ileal pouch-anal anastomosis (IPAA) 显示文摘 | Brazowski E Dotan I Tulchinsky H | 2009 | Pathol Res Pract2009，205，8： | 1 |
| 9 | MicroRNA Expression Signatures in Intraductal Papillary Mucinous Neoplasm of the Pancreas显示文摘 | N. Lubezky S. Lowenstein M. Ben-Haim E. Brazowski S. Marmor M. Pasmanik-Chor Varda Oron-Karni G. Rechavi J.M. Klausner G. Lahat | 2012 | Surgery2012，，： | 1 |
| 10 | Extramammary Paget's disease of the perianal region显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 11 | MicroRNA Expression Signatures in Intraductal Papillary Mucinous Neoplasm of the Pancreas显示文摘 | N. Lubezky S. Lowenstein M. Ben-Haim E. Brazowski S. Marmor M. Pasmanik-Chor Varda Oron-Karni G. Rechavi J.M. Klausner G. Lahat | 2012 | Surgery2012，，： | 1 |
| 12 | A prospective study of the clinical, genetic, screening, and pathologic features of a family with hereditary mixed polyposis syndrome 显示文摘 | Rozen P Samuel Z Brazowski E | 2003 | Am J Gastroenterol2003，98，10： | 1 |
| 13 | Pathobiology显示文摘 | Brazowski Eli Cohen Shlomi Yaron Ayala Filip Irina Eisenthal Avi | 2011 | Pathobiology2011，，6： | 1 |
| 14 | Clinical Presentation Can Predict Disease Course in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas显示文摘 | Nir Lubezky Menahem Ben-Haim Richard Nakache Guy Lahat Arye Blachar Eli Brazowski Erwin Santo Joseph M. Klausner | 2010 | World Journal of Surgery2010，，1： | 1 |
| 15 | Extramammary Paget's disease of the perianal region显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 16 | Extramammary Paget's disease of the perianal region显示文摘 | Tulchinsky H Zmora O Brazowski E | 2004 | Colorectal Dis2004，6，3： | 1 |
| 17 | Flat colorectal neoplasia: Idemification, pathogenesis and clinical significance 显示文摘 | ROZEN P BRAZOWSKI E | 2003 | Dig Liver Dis2003，35，3： | 1 |
| 18 | 遗传性混合型息肉综合征中环氧合酶-2的表达 | Brazowski E. Misonzhnick- Bedny F. Rozen P. 赵天智 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，7： | 0 |
| 19 | Management of pouch related symptoms in patients who underwent ileal pouch anal anastomosis surgery for adenomatous polyposis显示文摘BACKGROUND Adenomatous polyposis syndromes(APS)patients with ileal pouch anal anastomosis(IPAA)suffer frequent symptoms with scarce signs of inflammation,distinct from ulcerative colitis patients.While the management of pouchitis in ulcerative colitis patients is well established,data regarding response to treatment modalities targeting pouch-related disorders in APS patient population is scarce.AIM To assess clinical,endoscopic and histologic response to various treatment modalities employed in the therapy of pouch related disorders.METHODS APS patients who underwent IPAA between 1987-2019 were followed every 6-12 mo and pouch-related symptoms were recorded at every visit.Lower endoscopy was performed annually,recording features of the pouch,cuff and terminal ileum.A dedicated gastrointestinal pathologist reviewed biopsies for signs and severity of inflammation.At current study,files were retrospectively reviewed for initiation and response to various treatment modalities between 2015-2019.Therapies included dietary modifications,probiotics,loperamide,antibiotics,bismuth subsalicylate,mebeverine hydrochloride,5-aminosalicylic acid compounds and topical rectal steroids.Symptoms and endoscopic and histologic signs of inflammation before and after treatment were assessed.Pouchitis disease activity index(PDAI)and its subscores was calculated.Change of variables before and after therapy was assessed using Wilcoxon signed rank test for continuous variables and using McNemar's test for categorical variables.RESULTS Thirty-three APS patients after IPAA were identified.Before treatment,16 patients(48.4%)suffered from abdominal pain and 3(9.1%)from bloody stools.Mean number of daily bowel movement was 10.3.Only 4 patients(12.1%)had a PDAI≥7.Mean baseline PDAI was 2.5±2.3.Overall,intervention was associated with symptomatic relief,mainly decreasing abdominal pain(from 48.4%to 27.2%of patients,P=0.016).Daily bowel movements decreased from a mean of 10.3 to 9.3(P=0.003).Mean overall and clinical PDAI scores decreased from 2.58 to 1.94(P=0.016)and from 1.3 to 0.87(P=0.004),respectively.Analyzing each treatment modality separately,we observed that dietary modifications decreased abdominal pain(from 41.9%of patients to 19.35%,P=0.016),daily bowel movements(from 10.5 to 9.3,P=0.003),overall PDAI(from 2.46 to 2.03,P=0.04)and clinical PDAI(1.33 to 0.86,P=0.004).Probiotics effectively decreased daily bowel movements(from 10.2 to 8.8,P=0.007),overall and clinical PDAI(from 2.9 to 2.1 and from 1.38 to 0.8,P=0.032 and 0.01,respectively).While other therapies had minimal or no effects.No significant changes in endoscopic or histologic scores were seen with any therapy.CONCLUSION APS patients benefit from dietary modifications and probiotics that improve their pouch-related symptoms but respond minimally to anti-inflammatory and antibiotic treatments.These results suggest a functional rather than inflammatory disorder. | Ophir Gilad Guy Rosner Eli Brazowski Revital Kariv Nathan Gluck Hana Strul | 2021 | World Journal of Clinical Cases2021，9，32： | 0 |
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