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| 1 | 世界卫生组织(WHO)造血与淋巴组织肿瘤分类方案:临床顾问委员会会议报告显示文摘引言 :从 1995年开始 ,欧洲病理学工作者协会和血液病理学会一直致力于制定一个新的世界卫生组织 (WHO)血液恶性肿瘤分类方案 ,该分类方案包括淋巴系肿瘤、髓系肿瘤、组织细胞肿瘤和肥大细胞肿瘤。 材料与方法 :此项 WHO计划共组成十个病理学工作者委员会 ,负责确定病种和作出定义。另外还成立一个由国际血液学家和肿瘤学家组成的临床顾问委员会 (CAC)以保证该分类的临床实用性。 1997年 11月召开会议讨论了与该分类有关的临床问题。 结果 :WHO采纳了 1994年国际淋巴瘤研究组 (IL SG)报告的修订欧美淋巴系肿瘤分类 (REAL)方案作为淋巴系肿瘤的分类方案。该方案的分类方法遵循以下原则 :分类应是联合应用形态学、免疫表型、遗传特征及临床特征能够清楚界定的“真实存在”(“real”)病种的名录 ,上述各项特征的相对重要性因病种不同而异 ,不存在任何“金标准”。 WHO将 REAL分类原则延用于髓系肿瘤和组织细胞肿瘤 ,髓系肿瘤的分类包括联合应用细胞形态学和细胞遗传学异常能够界定的各个病种。围绕一系列临床问题召集的这次 CAC会议 ,就提交的大多数问题达成共识 ,这些问题及共识将详述于下。对于另外一些问题 ,CAC认为淋巴系肿瘤临床分组既无必要也不必需 ,患者的治疗取决于淋巴瘤的具体类型 ,如有? | N L Harris E S Jaffe J Diebold G Flandrin H K Muller-Hermelink J Vardiman T A Lister C D Bloomfield 张凤奎 郝玉书 | 2001 | 白血病.淋巴瘤2001，10，3： | 20 |
| 2 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 3 | Effects of age on outcome of tilt-table testing显示文摘 | Daniel Bloomfield Mathew Maurer J.Thomas Bigger | 1999 | The American Journal of Cardiology1999，，7： | 2 |
| 4 | A Practical Guide to Multimodality Imaging of Transcatheter Aortic Valve Replacement显示文摘 | Gerald S. Bloomfield Linda D. Gillam Rebecca T. Hahn Samir Kapadia Jonathon Leipsic Stamatios Lerakis Murat Tuzcu Pamela S. Douglas | 2012 | JACC: Cardiovascular Imaging2012，，4： | 2 |
| 5 | Continuous Therapy With Certolizumab Pegol Maintains Remission of Patients With Crohn’s Disease for up to 18 Months显示文摘 | Gary R. Lichtenstein Ole ?. Thomsen Stefan Schreiber Ian C. Lawrance Stephen B. Hanauer Ralph Bloomfield William J. Sandborn | 2010 | Clinical Gastroenterology and Hepatology2010，，7： | 2 |
| 6 | Reliability of S100B in predicting severity of central nervous system injury显示文摘 | Stephen M. Bloomfield James McKinney Les Smith Jonathan Brisman | 2007 | Neurocritical Care2007，，2： | 2 |
| 7 | Pembrolizumab-emerging treatment of pulmonary sarcomatoid carcinoma: A case report显示文摘BACKGROUND Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma(PSC),a rare,previously rapidly fatal subtype of nonsmall-cell lung cancer.CASE SUMMARY We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells.The patient was started on pembrolizumab and,after 5 cycles,there was a more than 80 percent decrease in the size of the tumor mass.Further decrease was seen at the end of 10 cycles.The patient has been tolerating pembrolizumab well,with no limiting side-effects.Fourteen months after first coming into the hospital,he remains asymptomatic.CONCLUSION Pembrolizumab appears as a viable emerging treatment for PSC. | Emanuela Cimpeanu Jibran Ahmed Wahib Zafar Adreana DeMarinis Svetoslav S Bardarov Shamim Salman Dennis Bloomfield | 2020 | World Journal of Clinical Cases2020，8，1： | 2 |
| 8 | Total ozone trends deduced from NIMBUS 7 TOMS data显示文摘 | Stolarski R S Bloomfield P Mcpelern R | 1991 | Geophys Res Letts1991，18，6： | 2 |
| 9 | The World Health Organization classification of neoplastic diseases of the haematopoietic and lymphoid tissues: report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997显示文摘 | Harris Jaffe Diebold Flandrin Muller‐Hermelink Vardiman Lister Bloomfield | 2001 | Histopathology2001，，1： | 2 |
| 10 | The inefficiency of least squares显示文摘 | BLOOMFIELD P WATSON G S | 1975 | Biometrika1975，62，： | 2 |
| 11 | Reliability of SIOOB in predicting severity of central nervous system injury显示文摘 | Bloomfield SM McKinney J Smith L | 2007 | Neurocrit Care2007，6，2： | 1 |
| 12 | Anti-biotic-coated spacers for total hip arthroplasty infection显示文摘 | BLOOMFIELD M R KLIKA A K BARSOUM W K | 2010 | Orthopedics2010，33，9： | 1 |
| 13 | The greater negative charge density of DNA in Tris-borate buffers does not enhance DNA condensation by multivalent cations显示文摘 | Schwinefus J J Bloomfield V A | 2000 | Biopolymers2000，54，： | 1 |
| 14 | 'Social Studies : the New Zealand Principal Post-Picot ' 显示文摘 | Bloomfield R | 1998 | Journal of Educational administration1998，32，4： | 1 |
| 15 | Ionic effects on the elasticity of single DNA molecules显示文摘 | BAUMANN C SMITH S BLOOMFIELD V A | 1997 | Proc Natl Acad Sci USA1997，94，： | 1 |
| 16 | Prevalence and development of additional cardiac abnormalities in 1448 patients with congenital ventricular septal defects显示文摘 | GLEN S BURNS J BLOOMFIELD P | 2004 | Heart2004，90，： | 1 |
| 17 | Current concepts of sepsis acute lung injury显示文摘 | SESSLERC N BLOOMFIELD G L FOWLER A A | 1996 | Clin Chest Med1996，17，2： | 1 |
| 18 | Strategic dependence and inherent risk assessments显示文摘 | Bloomfield Robert | 1995 | The Accounting Review1995，70，1： | 1 |
| 19 | Can transparent markets survive显示文摘 | O' Hara M | 2000 | Journal of Financial Economics2000，55，3： | 1 |
| 20 | Rapid calculation of regional cerebral blood flow and distribution volume using iodine-123-iodoamphetamine and dynamic SPECT显示文摘 | Ito H Iida H Bloomfield PM | 1995 | J Nuel Med1995，36，3： | 1 |
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