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579篇 您的检索式:作者名="Biase"
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1MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis b- and c-related-hepatocellularcarcinoma显示文摘Aim of the present review is to summarize the current knowledge about the potential relationship between mi RNAs and hepatitis B virus(HBV)-hepatitis C virus(HCV) related liver diseases. A systematic computerbased search of published articles, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Statement, was performed to identify relevant studies on usefulness of serum/plasma/urine mi RNAs, as noninvasive biomarkers for early detection of HBV and HCV-induced hepatocellular carcinoma(HCC) development, as well as for its prognostic evaluation. The used Medical Subject Headings terms and keywords were: 'HBV', 'HCV', 'hepatocellular carcinoma', 'micro RNAs', 'mi RNAs', 'diagnosis', 'prognosis', 'therapy', 'treatment'. Some serum/plasma mi RNAs, including mi R-21, mi R-122, mi-125a/b, mi R-199a/b, mi R-221, mi R-222, mi R-223, mi R-224 might serve as biomarkers for early diagnosis/prognosis of HCC, but, to date, not definitive results or well-defined panels of mi RNAs have been obtained. More well-designed studies, focusing on populations of different geographical areas and involving larger series of patients, should be carried out to improve our knowledge on the potential role of mi RNAs for HCC early detection and prognosis.Sirio Fiorino Maria Letizia Bacchi-Reggiani Michela Visani Giorgia Acquaviva Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Luca Di Tommaso Arrigo Bondi Sergio Sabbatani Andrea Domanico Carlo Fabbri Paolo Leandri Annalisa Pession Elio Jovine Dario de Biase 2016World Journal of Gastroenterology2016,22,15:25
2role of microRNAs in the main molecular pathways of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is the most common primary liver malignant neoplasia. HCC is characterized by a poor prognosis. The need to find new molecular markers for its diagnosis and prognosis has led to a progressive increase in the number of scientific studies on this topic. MicroRNAs(miRNAs) are small noncoding RNA that play a role in almost all main cellular pathways. miRNAs are involved in the regulation of expression of the major tumor-related genes in carcinogenesis, acting as oncogenes or tumor suppressor genes. The aim of this review was to identify papers published in 2017 investigating the role of miRNAs in HCC tumorigenesis. miRNAs were classified according to their role in the main molecular pathways involved in HCC tumorigenesis:(1) m TOR;(2) Wnt;(3) JAK/STAT;(4) apoptosis; and(5) MAPK. The role of miRNAs in prognosis/response prediction was taken into consideration. Bearing in mind that the analysis of miRNAs in serum and other body fluids would be crucial for clinical management, the role of circulating miRNAs in HCC patients was also investigated. The most represented mi RNA-regulated pathway in HCC is m TOR, but apoptosis, Wnt, JAK/STAT or MAPK pathways are also influenced by mi RNA expression levels. These miRNAs could thus be used in clinical practice as diagnostic, prognostic or therapeutic targets for HCC treatment.Francesco Vasuri Michela Visani Giorgia Acquaviva Thomas Brand Michelangelo Fiorentino Annalisa Pession Giovanni Tallini Antonia D’Errico Dario de Biase 2018World Journal of Gastroenterology2018,24,25:16
3Body weight, lifestyle, dietary habits and gastroesophageal reflux disease显示文摘While lifestyle modifications are currently used as firstline treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle measures is controversial. Our aim was to systematically review the pathogenetic link between overweight/ obesity, dietary habits, physical activity and GERD, and the beneficial effect of specific recommended changes, by means of the available literature from the 1999 to the present. Obesity, in particular, abdominal obesity, plays a key role in determining GERD symptoms and complications through mechanical and metabolic effects. Controlled weight loss (by diet or surgery) is effective in improving GERD symptoms. No definitive data exist regarding the role of diet and, in particular, of specific foods or drinks, in influencing GERD clinical manifestations. Moderate physical activity seems to be beneficial for GERD, while vigorous activity may be dangerous in predisposed individuals. In conclusion, being obese/overweight and GERD-specific symptoms and endoscopic features are related, and weight loss significantly improves GERD clinical-endoscopic manifestations. The role of dietary behavior, mainly in terms of specific dietary components, remains controversial. Mild routine physical activity in association with diet modifications, i.e. a diet rich in fiber and low in fat, is advisable in preventing reflux symptoms.Davide Festi Eleonora Scaioli Fabio Baldi Amanda Vestito Francesca Pasqui Anna Rita Di Biase Antonio Colecchia 2009World Journal of Gastroenterology2009,15,14:8
4Review article: the diagnosis of non‐alcoholic fatty liver disease – availability and accuracy of non‐invasive methods显示文摘D. Festi R. Schiumerini L. Marzi A. R. Di Biase D. Mandolesi L. Montrone E. Scaioli G. Bonato G. Marchesini‐Reggiani A. Colecchia 2012Aliment Pharmacol Ther2012,,4:6
5Acute coronary syndrome: a rare case of multiple endocrine neoplasia syndromes with pheochromocytoma and medullary thyroid carcinoma显示文摘Pheochromocytoma is a tumor arising from neuroectodermal chromaffin tissues in the adrenal gland or extra-adrenal paraganglia(paragangliomas). The prevalence of the tumor is 0.1%-0.6% in the hypertensive population, of which 10%-20% are malignant. Pheochromocytoma produces, stores, and secretes catecholamines, as well as leads to hypertensive crisis, arrhythmia, angina, and acute myocardial infarction without coronary artery diseases. We report a case of acute coronary syndrome(ACS) with a final diagnosis of multiple endocrine neoplasia with pheochromocytoma and medullary thyroid carcinoma(MTC).Alessadro Maloberti Paolo Meani Roberto Pirola Marisa Varrenti Marco Boniardi Anna Maria De Biase Paola Vallerio Edgardo Bonacina Giuseppe Mancia Paola Loli Cristina Giannattasio 2015Cancer Biology & Medicine2015,12,3:4
6Measurement of Spleen Stiffness to Evaluate Portal Hypertension and the Presence of Esophageal Varices in Patients With HCV-Related Cirrhosis显示文摘Antonio Colecchia Lucia Montrone Eleonora Scaioli Maria Letizia Bacchi–Reggiani Agostino Colli Giovanni Casazza Ramona Schiumerini Laura Turco Anna Rita Di Biase Giuseppe Mazzella Luca Marzi Umberto Arena Massimo Pinzani Davide Festi 2012Gastroenterology2012,,3:3
7Reduced levels of N-terminal-proatrial natriuretic peptide in hypertensive patients with metabolic syndrome and their relationship with left ventricular mass显示文摘Speranza Rubattu Sebastiano Sciarretta Giuseppino Massimo Ciavarella Vanessa Venturelli Paola De Paolis Giuliano Tocci Luciano De Biase Andrea Ferrucci Massimo Volpe 2007Journal of Hypertension2007,,4:2
8Left Atrial Appendage Studied by Computed Tomography to Help Planning for Appendage Closure Device Placement显示文摘YANWANG LUIGIDI BIASE RODNEY P.HORTON TUANNGUYEN PRASANTMORHANTY ANDREANATALE 2010Journal of Cardiovascular Electrophysiology2010,,9:2
9Diversity, frequency, and geographic distribution of facultative bacterial endosymbionts in introduced aphid pests显示文摘在昆虫的容许的细菌的 endosymbionts 在最后年期间在强烈学习下面。Endosymbionts 能修改昆虫显型,授与在环境应力下面的适应优点。,这为一组全球农业的蚜虫害虫似乎特别地相关 endosymbionts 修改关键健康相关的特点包括主人植物使用,对生来的敌人和热忍耐的保护。试图在介绍蚜虫害虫,分发和许多的成功上理解容许的 endosymbionts 的角色 5 容许的 endosymbionts ( Hamiltonella defensa , Regiella insecticola , Serratia symbiotica ,立克次休属微生物和 Spiroplasma )在 4 个谷物蚜虫被学习并且比较( Sitobion avenae , Diuraphis noxia , Metopolophium dirhodum 和 Schizaphis graminium )并且在从在智利的 2 个 agroclimatic 地区的豌豆蚜虫 Acyrthosiphon pisum 建筑群。总的来说,有容许的 endosymbionts 的感染展出了取决于蚜虫种类 / 主人赛跑和地理地区的一个高度可变、典型的模式,它能在他们的介绍以后解释蚜虫害虫人口的成功。当时 S。symbiotica 和 H。defensa 是 A 带的最经常的 endosymbionts。pisum 豌豆赛跑和 A。分别地,最经常的容许的 endosymbiont 由所有谷物蚜虫带了的 pisum 苜蓿赛跑蚜虫是 R。insecticola。有趣地, endosymbionts 的一篇高度可变的作文由 S 带了。avenae 也在 agroclimatic 地区之间被观察,建议 endosymbionts 正在回答到不能生活的变量(温度和猛冲) 的差别。另外,我们的调查结果在以前没屏蔽的谷物蚜虫种类组成细菌的 endosymbionts 的第一份报告,并且也,第一在智利蚜虫 endosymbionts 报导。Daniela A. Sepulvedat Francisca Zepeda-Paulo Claudio C. Ramfrez Bias Lavandero Christian C. Figueroa 2017Insect Science2017,24,3:2
10Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis显示文摘BACKGROUND The proton pump inhibitors(PPIs),used to reduce gastric acid secretion,represent one of the most widely used pharmaceutical classes in the world.Their consumption as a risk factor for the evolution of severe forms of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection has been investigated as well as the mortality of these patients.These risks also appear to be linked to the duration and the dosage.On the other hand,several studies have emerged with regard to the protective or therapeutic effects of these drugs.More and more evidence underlines the immunomodulatory and anti-fibrotic role of PPIs.In addition,their ability to alkalize the contents of endosomes and lysosomes serves as an obstacle to the entry of the virus into the host cells.AIM To identify studies on the relationship between the intake of PPIs and coronavirus disease 2019(COVID-19)in patients affected by SARS-CoV-2 infection,with the main objective of evaluating the outcomes related to severity and mortality.METHODS A literature review was performed in November 2020.The MEDLINE/PubMed,Cochrane Library,EMBASE and Google Scholar databases were searched for all relevant articles published in English on this topic.The search terms were identified by means of controlled vocabularies,such as the National Library of Medicine’s MESH(Medical Subject Headings)and keywords.The MESH terms and keywords used were as follows:“COVID-19”,“proton pump inhibitors”,“PPIs”,“SARS-CoV-2”,“outcomes”,“severity”and“mortality”.The inclusion criteria regarding the studies considered in our analysis were:meta-analysis,casecontrol,hospital-based case-control,population-based case-control,retrospective studies,online survey,as well as cohort-studies,while articles not published as full reports,such as conference abstracts,case reports and editorials were excluded.We tried to summarize and pool all the data if available.RESULTS A total of 9 studies were found that described the use of PPIs,of which only 5 clearly reported the severity and mortality data in SARS-CoV-2 patients.Our pooled incidence analysis of severe events did not differ between patients with and without PPIs(odds ratio 1.65,95%confidence interval:0.62-4.35)(P=0.314),or for mortality(odds ratio 1.77,95%confidence interval:0.62-5.03)(P=0.286).CONCLUSION Detailed and larger case studies are needed to accurately understand the role of PPIs in this viral infection.Maddalena Zippi Sirio Fiorino Roberta Budriesi Matteo Micucci Ivan Corazza Roberta Pica Dario de Biase Claudio Giuseppe Gallo Wandong Hong 2021World Journal of Clinical Cases2021,9,12:2
11Differential expression of the down regulatory function of CD8 cells in Triehosanthin-induced immunosupplession and its genetic control in humans显示文摘Chou KY Chan M Bias WB 1996Eur J Immunogenetics1996,23,:1
12Stability and oligomerization of recombinant GadX, a transcriptional activator of the Escherichia coli glutamate decarboxylase system显示文摘TRAMONTI A DE CANIO M DE BIASED 2003Biochim Biophysic Aeta2003,1647,:1
13Estimation of soil water repellency of different particle size fractions in relation with carbon content by different methods 显示文摘Rodriguez-Alleres M de Bias E Benito E 2007Science of the Total Environment2007,378,12:1
14Forecast of hourly average wind speed with ARMA models in Navarre (Spain) 显示文摘Torres J L Garcia A Bias M D 2005Solar Energy2005,79,1:1
15Does the left atrial appendage morphology correlate with the risk of stroke in patients with atrial fibrillation? Results from a multicenter study显示文摘Di Biase L Santangeli P Anselmino M 2012J Am Coil Cardiol2012,60,:1
16Osteoarthritis associat- ed with estrogen deficiency 显示文摘Roman -Bias JA Castaneda S Largo R 2009Arthritis Res Ther2009,11,5:1
17Antigenic variation among transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus strains detected with monoclonal antibodies to the S protein of TGEV显示文摘SIMKINS R A WEILNAU P A BIAS J 1992Am J Vet Res1992,53,7:1
18Ablation of atrial fibrillation utilizing robotic catheter navigation in comparison to manual navigation and ablation:single-center experience显示文摘Di Biase L Wang Y Horton R Gallinghouse G J Mohanty P Sanchez J 0,,:1
19Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells ( HL60, NB4 ) Protein kinase modulation and reactive oxygen species generation 显示文摘Sanehez Y Amran D de Bias E 2009Bioehem Pharmacol2009,77,3:1
20Familial clustering of helcoacter pylori infection:population based study显示文摘DOMINICI P BELLENTANI S BIASE ARD 1999BMJ1999,319,:1
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