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| 1 | Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease显示文摘AIM To evaluate the pathogenic role of toll-like receptor(TLR) gene polymorphisms in patients with nonalcoholic fatty liver disease(NAFLD).METHODS Two hundred and fifty subjects(NAFLD = 200, healthy volunteers = 50) underwent polymerase chain reaction and restriction fragment length polymorphism to assess one polymorphism in the toll-like receptor 2(TLR2) gene(A753G), two polymorphisms in the TLR4 gene(TLR4 Asp299 Gly and Thr399 Ile allele), and two polymorphisms in the cluster of differentiation 14(CD14)(C-159 T and C-550T) gene, a co-receptor of TLR4. Association of TLR gene polymorphisms with NAFLD and its severity was evaluated by genetic models of association.RESULTS On both multiplicative and recessive models of gene polymorphism association, there was significant association of CD14 C(-159) T polymorphism with NAFLD; patients with TT genotype had a 2.6 fold increased risk of developing NAFLD in comparison to CC genotype. There was no association of TLR2 Arg753 Gln, TLR4 Asp299 Gly, Thr399 Ile, and CD14 C(-550) T polymorphisms with NAFLD. None of the TLR gene polymorphisms had an association with histological severity of NAFLD.CONCLUSION Patients with CD14 C(-159) T gene polymorphism, a co-receptor of TLR4, have an increased risk of NAFLD development. | Shweta Kapil Ajay Duseja Bal Krishan Sharma Bhupesh Singla Anuradha Chakraborti Ashim Das Pallab Ray Radha K Dhiman Yogesh Chawla | 2016 | World Journal of Gastroenterology2016，22，42： | 7 |
| 2 | A cesium fluoride promoted efficient and rapid multicomponent synthesis of functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives显示文摘A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time(5–10 min), and use of an inexpensive catalyst. | Yogesh B.Wagh Yogesh A.Tayade Swapnil A.Padvi Bhupesh S.Patil Nilesh B.Patil Dipak S.Dalal | 2015 | Chinese Chemical Letters2015，26，10： | 3 |
| 3 | Effects of defects on the electronic properties of WTe_2 armchair nanoribbons显示文摘We have investigated the electronic properties of WTe2 armchair nanoribbons with defects.WTe2 nanoribbons can be categorized depending on the edge structure in two types:armchair and zigzag.WTe2 in its bulk form has an indirect band gap but nanoribbons and nanosheets of WTe2 have direct band gaps.Interestingly,the zigzag nanoribbon is metallic while the armchair nanoribbons are semiconducting.Thus they can find applications in device fabrication.Therefore,it is very important to study the effect of defects on the electronic properties of the armchair nanoribbons as these defects can impair the device properties and characteristics.We have considered defects such as:vacancy,rough edge,wrap,ripple and twist in this work.We report the band gap variation with these defects.We have also studied the change in band gap and total energy with varying degrees of wrap,ripple and twist. | Bahniman Ghosh Abhishek Gupta Bhupesh Bishnoi | 2014 | Journal of Semiconductors2014，35，11： | 2 |
| 4 | Temperature effect on hetero structure junctionless tunnel FET显示文摘For the first time, we investigate the temperature effect on Al Ga As/Si based hetero-structure junctionless double gate tunnel field effect transistor. Since junctionless tunnel FET is an alternative substitute device for ultra scaled deep-submicron CMOS technology, having very good device characteristics such as an improved subthreshold slope(< 60 m V/decade at 300 K) and very small static leakage currents. The improved subthreshold slope and static leakage current confirms that it will be helpful for the development of future low power switching circuits. The 2-D computer based simulation results show that OFF-state leakage current is almost temperature independent for the proposed device structure. | Shiromani Balmukund Rahi Bahniman Ghosh Bhupesh Bishnoi | 2015 | Journal of Semiconductors2015，36，3： | 2 |
| 5 | Temperature and pressure effects on supercritical CO2 extraction of tomato seed oil显示文摘 | Bhupesh C.Roy MotonobuGoto TsutomuHirose | 2003 | International Journal of Food Science & Technology2003，，2： | 1 |
| 6 | Levofloxacin-Induced Radiation Recall Dermatitis: A Case Report and a Review of the Literature显示文摘 | A. Gabriella Wernicke Alexander J. Swistel Bhupesh Parashar Patricia L. Myskowski | 2010 | Clinical Breast Cancer2010，，5： | 1 |
| 7 | Chemotherapy Significantly Increases the Risk of Radiation Pneumonitis in Radiation Therapy of Advanced Lung Cancer显示文摘 | Bhupesh P Alison E Rajeev M | | 0，，02： | 1 |
| 8 | Current and past cigarette smoking significantly increase risk for microscopic colitis显示文摘 | Eugene F. Yen Bhupesh Pokhrel Hongyan Du Steven Nwe Laura Bianchi Benjamin Witt Curtis Hall | 2011 | Inflamm Bowel Dis2011，，10： | 1 |
| 9 | Extraction of ginger oil with supercritical carbon dioxide:experiments and Modeling 显示文摘 | Bhupesh C R Motonobu G Tsutomu H | 1996 | Ind Eng Chem Res1996，35，2： | 1 |
| 10 | CASE 4-2013 large ascending aortic and arch aneurysm:an unusual cause of preoperative airway compromise 显示文摘 | SUJANA D BHUPESH K GOYERDHAN D P | 2013 | J Cardiothor Vascan2013，27，4： | 1 |
| 11 | Prevalence of highrisk human papillomavirus (HR-HPV) types 16 and 18 in healthy women with cytologically negative Pap smear显示文摘 | Raksha A Arunaz K Bhupesh KP | 2005 | European Journal of Obstetrics & Gynecology and Reproductive Biology2005，121，1： | 1 |
| 12 | A regional analysis of the fate and transport of mercury in East Asia and an assessment of major uncertainties 显示文摘 | Li P Gregory R C Bhupesh A | 2008 | Atmospheric Environment2008，，： | 1 |
| 13 | Left atrial myxoma, ruptured chordae tendinae causing mitral regurgitation and coronary artery disease显示文摘 | Bhupesh Kumar Ravi Raj Aveek Jayant Sachin Kuthe | 2014 | Annals of Cardiac Anaesthesia2014，，2： | 1 |
| 14 | Structurals of bacillomycin D and bacillomycin L peptidolipid antibiotics from Bacillus subtilis显示文摘 | Francoise P Marie T P Bhupesh C | 1984 | The Journal of Antibiotics1984，37，12： | 1 |
| 15 | Human papillomavirus type 16 variant analysis of E6 ,E7 ,and L1 genes and long control region in biopsy samples from cervical cancer patients in North India显示文摘 | Shailja P Neeraj J Bhupesh KIP | 2008 | J Clin Microbio12008，46，3： | 1 |
| 16 | Optimal maintenance schedule decisions for machine tools considering the user's cost structure显示文摘 | BHUPESH K L MAKARAND S K | 2012 | International Journal of Production Research2012，50，20： | 1 |
| 17 | New Chiral Isoquinolinium Salt Derivatives from Chiral Primary Amines via the Zincke Reaction 显示文摘 | Barbier D Marazano C Das Bhupesh C | 1996 | J Org Chem1996，61，26： | 1 |
| 18 | Chemotherapy Significant- ly Increases the Risk of Radiation Pneumonitis in Radiation Thera- py of Advanced Lung Cancer 显示文摘 | Bhupesh P Alison E Rajeev M | 2011 | Am J Chin Oncol2011，34，2： | 1 |
| 19 | Chemotherapy significantly increases the risk of radiation pneumonitis in radiation therapy of ad- vanced lung cancer显示文摘 | Bhupesh P Alison E Rajeev M | 2011 | Am J Chin Oncol2011，34，2： | 1 |
| 20 | Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats显示文摘 | Bhupesh Sharma Nirmal Singh | 2011 | Pharmacology Biochemistry and Behavior2011，，2： | 1 |
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