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| 1 | 新加坡最大回用水处理厂污水短程硝化厌氧氨氧化脱氮工艺显示文摘总结了新加坡樟宜回用水处理厂4次采样的结果,该厂日处理城市污水80万t.在好氧区很好地实现了部分硝化和亚硝酸盐积累,其中好氧氨氧化率平均为72.2%,亚硝酸盐积累率平均为76.0%.在缺氧区氨氮和亚硝酸盐得到了同步去除(厌氧氨氧化).物料衡算结果表明:初沉池的出水总氮的37.5%是通过自养脱氮去除,27.1%是通过传统的硝化/反硝化脱氮去除,其余部分总氮则存在于活性污泥和出水中.微生物和动力学研究表明:短悬浮或游离的厌氧氨氧化菌可存在于污泥龄较短的污水处理系统.最后从出水氮质量浓度、pH、碱度、曝气能耗及反应器容积等方面,将樟宜回用水处理厂的分段进水活性污泥法工艺与新加坡其他3个回用水处理厂的MEL/LE工艺进行了对比分析. | Cao Yeshi Kwok Bee Hong Yan Zhou Yu Liu He Jianzhong Chua Seng Chye Wah Yuen Long Yahya Ghani | 2015 | 北京工业大学学报2015，41，10： | 32 |
| 2 | Determination of aflatoxins in animal feeds by HPLC with multifunctional column clean-up显示文摘 | Wejdan Shakir Khayoon Bahruddin Saad Chew Bee Yan Nor Hasani Hashim Abdussalam Salhin Mohamed Ali Muhammad Idiris Salleh Baharuddin Salleh | 2009 | Food Chemistry2009，，3： | 2 |
| 3 | Productivity and the Export Market; A Firm-level Analysis 显示文摘 | Bee Yan Aw Amy Hwang | 1995 | Journal of Development Economics1995，47，2： | 1 |
| 4 | R & D Invest- ments, Exporting, and the Evolution of Firm Productivity 显示文摘 | Aw Bee Yan Mark J Roberts Daniel Yi Xu | 2008 | American Economic Review2008，98，2： | 1 |
| 5 | Firm Heterogeneity and Location Choice of Taiwanese Multinationals显示文摘 | Aw Bee Yan and Yi Lee | 2008 | Journal of International Economics2008，75，1： | 1 |
| 6 | Productivity and Turnover in the Export Market:Micro Evidence from Taiwan and South Korea显示文摘 | Aw Bee Yan Chung Sukkyun Roberts MarkJ | 2000 | The World Bank Economic Review2000，，： | 1 |
| 7 | R&D Investment, Ex- porting and Productivity Dynamics 显示文摘 | Aw Bee Yan Mark J Roberts Daniel Yi Zu | 2011 | American Economic Re- view2011，101，4： | 1 |
| 8 | Viral Quasi-Species Evolution During Hepatitis Be Antigen Seroconversion显示文摘 | Seng Gee Lim Yan Cheng Stephane Guindon Bee Leng Seet Lay Yong Lee Peizhen Hu Shanthi Wasser Frank Josef Peter Theresa Tan Matthew Goode Allen Gerard Rodrigo | 2007 | Gastroenterology2007，，3： | 1 |
| 9 | Productivity and Turnover in the Export Market:MicroGlevel Evidence from the Republic of Korea and Taiwan(China)显示文摘 | Aw Bee Yan Sukkyun Chung Mark J Roberts | | 0，，： | 1 |
| 10 | Complete Genome Sequence of a Novel H9N2 Subtype Influenza Virus FJG9 Strain in China Reveals a Natural Reassortant Event显示文摘 | Qingmei Xie Zhuanqiang Yan Jun Ji Huanmin Zhang Jun Liu Yue Sun Guangwei Li Feng Chen Chunyi Xue Jingyun Ma Yingzuo Bee | 2012 | Journal of Virology2012，，18： | 1 |
| 11 | Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip显示文摘The identification of tumor-related microRNAs(miRNAs)exhibits excellent promise for the early diagnosis of cancer and other bioanalytical applications.Therefore,we developed a sensitive and efficient biosensor using polyadenine(polyA)-mediated fluorescent spherical nucleic acid(FSNA)for miRNA analysis based on strand displacement reactions on gold nanoparticle(AuNP)surfaces and electrokinetic signal amplification(ESA)on a microfluidic chip.In this FSNA,polyA-DNA biosensor was anchored on AuNP surfaces via intrinsic affinity between adenine and Au.The upright conformational polyA-DNA recognition block hybridized with 6-carboxyfluorescein-labeled reporter-DNA,resulting in fluorescence quenching of FSNA probes induced by AuNP-based resonance energy transfer.Reporter DNA was replaced in the presence of target miRNA,leading to the recovery of reporter-DNA fluorescence.Subsequently,reporter-DNAs were accumulated and detected in the front of with Nafion membrane in the microchannel by ESA.Our method showed high selectivity and sensitivity with a limit of detection of 1.3 pM.This method could also be used to detect miRNA-21 in human serum and urine samples,with recoveries of 104.0%-113.3% and 104.9%-108.0%,respectively.Furthermore,we constructed a chip with three parallel channels for the simultaneous detection of multiple tumor-related miRNAs(miRNA-21,miRNA-141,and miRNA-375),which increased the detection efficiency.Our universal method can be applied to other DNA/RNA analyses by altering recognition sequences. | Jun Xu Qing Tang Runhui Zhang Haoyi Chen Bee Luan Khoo Xinguo Zhang Yue Chen Hong Yan Jincheng Li Huaze Shao Lihong Liu | 2022 | Journal of Pharmaceutical Analysis2022，12，5： | 0 |
| 12 | Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces hosts for natural product discovery显示文摘With the advent of rapid automated in silico identification of biosynthetic gene clusters(BGCs),genomics pre-sents vast opportunities to accelerate natural product(NP)discovery.However,prolific NP producers,Strepto-myces,are exceptionally GC-rich(>80%)and highly repetitive within BGCs.These pose challenges in sequencing and high-quality genome assembly which are currently circumvented via intensive sequencing.Here,we outline a more cost-effective workflow using multiplex Illumina and Oxford Nanopore sequencing with hybrid long-short read assembly algorithms to generate high quality genomes.Our protocol involves subjecting long read-derived assemblies to up to 4 rounds of polishing with short reads to yield accurate BGC predictions.We successfully sequenced and assembled 8 GC-rich Streptomyces genomes whose lengths range from 7.1 to 12.1 Mb with a median N50 of 8.2 Mb.Taxonomic analysis revealed previous misrepresentation among these strains and allowed us to propose a potentially new species,Streptomyces sydneybrenneri.Further comprehensive characterization of their biosynthetic,pan-genomic and antibiotic resistance features especially for molecules derived from type I polyketide synthase(PKS)BGCs reflected their potential as alternative NP hosts.Thus,the genome assemblies and insights presented here are envisioned to serve as gateway for the scientific community to expand their avenues in NP discovery. | Elena Heng Lee Ling Tan Dillon W.P.Tay Yee Hwee Lim Lay-Kien Yang Deborah C.S.Seow Chung Yan Leong Veronica Ng Siew Bee Ng Yoganathan Kanagasundaram Fong Tian Wong Lokanand Koduru | 2023 | Synthetic and Systems Biotechnology2023，8，2： | 0 |
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