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| 1 | Spontaneous bacterial peritonitis显示文摘Since its initial description in 1964,research hastransformed spontaneous bacterial peritonitis (SBP)from a feared disease (with reported mortality of 90%)to a treatable complication of decompensated cirrhosis,albeit with steady prevalence and a high recurrencerate. Bacterial translocation,the key mechanism in thepathogenesis of SBP,is only possible because of theconcurrent failure of defensive mechanisms in cirrhosis.Variants of SBP should be treated. Leucocyte esterasereagent strips have managed to shorten the 'tap-to-shot' time,while future studies should look into theircombined use with ascitic fluid pH. Third generationcephalosporins are the antibiotic of choice becausethey have a number of advantages. Renal dysfunctionhas been shown to be an independent predictor ofmortality in patients with SBP. Albumin is felt to reducethe risk of renal impairment by improving effectiveintravascular volume,and by helping to bind pro-inflammatory molecules. Following a single episodeof SBP,patients should have long-term antibioticprophylaxis and be considered for liver transplantation. | Anastasios Koulaouzidis Shivaram Bhat Athar A Saeed | 2009 | World Journal of Gastroenterology2009，15，9： | 31 |
| 2 | Omental flaps reduces complications after pancreaticoduodenectomy显示文摘BACKGROUND:Major complications after pancreaticoduodenectomy are usually caused by a leaking pancreaticojejunal anastomosis.Omental flaps around various anastomoses were used to prevent the formation of fistula.METHODS:We reviewed 147 patients who had undergone pancreaticoduodenectomy between March 2006 and March2012.The patients were divided into 2 groups according to the application of omental flaps around various anastomoses:group A(101 patients)who underwent omental wrapping procedure;group B(46 patients)who did not undergo the omental wrapping procedure.Perioperative data of the two groups were reviewed to assess the effectiveness of omental flap procedure in the prevention of pancreatic fistula and other complications.RESULTS:No differences were observed in the clinical characteristics between the 2 groups.The incidences of pancreatic fistula(4.0%vs 17.4%),post-pancreatectomy hemorrhage(0vs 6.5%),biliary fistula(1.0%vs 13.0%),and delayed gastric emptying(4.0%vs 17.4%)were significantly less frequent in group A.The overall morbidity(18.8%vs 47.8%)and hospital stay(8.3 vs 9.6 days)were also significantly lower in group A than in group B.CONCLUSIONS:Omental flaps around various anastomoses after pancreaticoduodenectomy can reduce the incidences of pancreatic fistula,biliary fistula,post-pancreatectomy hemorrhage and delayed gastric emptying.This procedure is simple and effective to reduce the overall morbidity after pancreaticoduodenectomy. | Omar J Shah Sadaf A Bangri Manmohan Singh Reyaz A Lattoo Mohammad Y Bhat | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，3： | 19 |
| 3 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020，28，5： | 9 |
| 4 | A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valley显示文摘瞄准:为了系统地检验风险因素的关联的程度,例如年龄,与原因的体的 Tp53 分子损害消费了饮食的习惯和家庭倾向在北印度的 Kashmiri 人口之中提高食道的有鳞的房间癌(ESCC ) 的致癌作用严厉。方法:所有情况(n = 51 ) 并且控制(n = 150 ) 是克什米尔山谷的永久居民。基因改变在 Tp53 肿瘤的前 ons 5-8 被决定压制或在 45 个 ESCC 盒子之中的基因组织学地由 PCR-SSCP 分析证实了。为单个癌症盒子的数据(n = 45 ) 并且住院病人控制(n = 150 ) 与非癌症,疾病在癌症的家庭历史上包括了信息,与病人的年龄组一起的三十个占优势的普通饮食的风险因素。在到从这些参数的万物有灵论的数据的 p53 前 ons 的基因损害的关联被 Chi 平方测试与健康控制一起产生到所有 45 个组织学地证实的 ESCC 盒子。结果:(77.8%) 45 中的 35 个组织学地描绘了与 45 正常样品中的 1 个对比的有的类似的体细胞突变从一样的耐心的显示出的细菌线变化从邻近的区域获得了的肿瘤样品。 SSCP 分析表明了改变在 6 上在前被发现的那很普通的 p53 基因(77.7%),那没与个人和 clinicopathological 参数的年龄相关,但是与癌症的家庭历史显示出重要词语索引( P<0.05 )( CD = 58 ),在消费的一个未知地点,和饮食的习惯建议细菌线倾向局部地种芥属蔬菜“ Hakh ”( CD = 19.5 ),红 chillies ( CD = 20.2 ),热咸苏打茶( CD = 2.37 )并且本地烤的面包( CD = 1.1 )。结论:我们的学习建议那体的染色体变化特别在 6 Tp53 基因上的前,在人种上的食道的癌症病人之中,克什米尔山谷的同质的人口是仔细与到各种各样的普通饮食的风险因素,特别热的咸茶,肉,烤的面包和“ Hakh ”的继续的暴露有关,那富于 nitrosoamines 和家庭癌症历史。 | Imtiyaz Murtaza Dhuha Mushtaq Mushtaq A Margoob Amit Dutt Nisar Ahmad Wani Ishfaq Ahmad Mohan Lal Bhat | 2006 | World Journal of Gastroenterology2006，12，25： | 8 |
| 5 | A selective approach to the surgical management of periampullary cancer patients and its outcome显示文摘BACKGROUND: Pancreaticoduodenectomy is a high risk, complex, technically challenging operation associated with significant perioperative morbidity and mortality. This study on the surgical management of periampullary cancer patients is based on our experience in a period of nearly 13 years.METHODS: The study was conducted on two groups of patients: group A included 42 patients who were treated between January 2000 and September 2005 and group B included 134 patients who were treated between October 2005 to October 2012. Preoperative, intraoperative and postoperative details of all these patients were collected, tabulated and analyzed to assess the impact of the selective approach introduced in the department with effect from October 2005.RESULTS: Intraoperative details revealed highly significant differences in the management of the two groups of patients in respect of operative time (250.4 vs 126.6 minutes; P<0.001), operative blood loss (1070.2 vs 414.9 m L; P<0.001) and intraoperative blood transfusion (1.4 vs 0.2 units; P<0.001). Variations between the two groups in the frequency of complications were found to be statistically insignificant. However, the difference between the two groups in the overall morbidity of patients (47.6% vs 26.1%; P=0.009) and the length of their hospital stay (11.8 vs 7.8 days; P<0.001) were significant.CONCLUSION: A selective approach applied to the surgical management of periampullary cancer patients is a step in the right direction. | Omar J Shah Irfan Robbani Parveen Shah Sadaf A Bangri Irfan J Khan Mohammad Y Bhat Manmohan Singh | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 3 |
| 6 | Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activa tion in prostate epithelial cells 显示文摘 | CHIPUK J E BHAT M HSING A Y | 2001 | J Biol Chem2001，276，26： | 1 |
| 7 | Diminished lung function, RSV infection, and respiratory morbidity in prematurely born infants 显示文摘 | Broughton S Bhat R Roberts A | 2006 | Arch Dis Child2006，91，1： | 1 |
| 8 | Catalytic activity of oxides and halides on hydrogen storage of MgH2 显示文摘 | Bhat V V Rougier A Aymard L | 2006 | Power Sources2006，159，： | 1 |
| 9 | Output-feedback semiglobal stabilization of stall dynamics for preventing hysteresis and surge in axial-flow compressors显示文摘 | CHATURVEDI N A BHAT S P | 2006 | IEEE Trans Control Syst Technol2006，14，2： | 1 |
| 10 | Evaluation of resistance of teeth sub-jected to fracture after endodontic treatment using different root ca-nal sealers:an in vitro study显示文摘 | Bhat SS’Hegde SK Rao A | 2012 | J Indian Soc Pedod Prev Dent2012，30，4： | 1 |
| 11 | Bacillus subtilis natto:a non-toxic source of poly-γ-glutamic acid that could be used as a cryoprotectant for probiotic bacteria显示文摘 | BHAT A R IRORERE V U BARTLETT T | 2013 | AMB Express2013，3，1： | 1 |
| 12 | Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions显示文摘 | Miller A G Smith D G Bhat M | 2006 | J Biol Chem2006，281，11： | 1 |
| 13 | Predictors of mortality inacute renal failure in a developing counry : a prospective study显示文摘 | Kohli HS Bhat A Aravindan AN | 2007 | Renal Failure2007，29，46： | 1 |
| 14 | Evidence that neu- ronal nitric oxide synthase but not heine oxygenase increases in the hypothalamus on proestrus afternoon显示文摘 | Lamar C A Bhat G K Mahesh V B | 1999 | Neuroendocrinology1999，70，5： | 1 |
| 15 | Cytokine induction of induc- ible nitric oxide synthase in an oligodendrocyte cell line:role of p38 mitogen-activated protein kinase activation显示文摘 | BHAT N ZHANG P BHAT A | 1999 | J Neu- rochem1999，72，： | 1 |
| 16 | Trapezial space height measure- ment after trapezieetomy: a comparison of the use of standard and stress radiographs显示文摘 | Bhat M Davis TR Bannerjee A | 2003 | J Hand Surg Am2003，28，3： | 1 |
| 17 | Commuter Bicyclist Route Choice: Analysis Using a Stated Preference Survey显示文摘 | Stinson M A Bhat C R | 2003 | Transportation Research Record: Journal of the Transportation Research Board2003，1828，： | 1 |
| 18 | An adaptive audio watermarking based on the singular value decomposition in the wavelet domain 显示文摘 | BHAT V SENGUPTA I DAS A | 2010 | Digital Signal Processing2010，20，6： | 1 |
| 19 | Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression显示文摘 | Leandro Z. Agudelo Teresa Femenía Funda Orhan Margareta Porsmyr-Palmertz Michel Goiny Vicente Martinez-Redondo Jorge C. Correia Manizheh Izadi Maria Bhat Ina Schuppe-Koistinen Amanda T. Pettersson Duarte M.S. Ferreira Anna Krook Romain Barres Juleen R. Zi | 2014 | Cell2014，，1： | 1 |
| 20 | New aspects in the stabilization of acrylic fibers for carbon fibers 显示文摘 | Bhat G S Cook F L Abhiraman A S | 1990 | Carbon1990，28，23： | 1 |
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