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| 1 | Phase 1 human trial of autologous bone marrow-hematopoietic stem cell transplantation in patients with decompensated cirrhosis显示文摘AIM: To evaluate safety and feasibility of autologous bone marrow-enriched CD34+ hematopoietic stem cell Tx through the hepatic artery in patients with decompensated cirrhosis.METHODS: Four patients with decompensated cirrhosis were included. Approximately 200 mL of the bone marrow of the patients was aspirated, and CD34+ stem cells were selected. Between 3 to 10 million CD34+ cells were isolated. The cells were slowly infused through the hepatic artery of the patients.RESULTS: Patient 1 showed marginal improvement in serum albumin and no significant changes in other test results. In patient 2 prothrombin time was decreased; however, her total bilirubin, serum creatinine, and Model of End-Stage Liver Disease (MELD) score worsened at the end of follow up. In patient 3 there was improvement in serum albumin, porthrombin time (PT), and MELD score. Patient 4 developed radiocontrast nephropathy after the procedure, and progressed to type 1 hepatorenal syndrome and died of liver failure a few days later. Because of the major side effects seen in the last patient, the trial was prematurely stopped.CONCLUSION: Infusion of CD34+ stem cells through the hepatic artery is not safe in decompensated cirrhosis. Radiocontrast nephropathy and hepatorenal syndrome could be major side effects. However, this study doesnot preclude infusion of CD34+ stem cells through other routes. | Mehdi Mohamadnejad Mehrnaz Namiri Mohamad Bagheri Seyed Masiha Hashemi Hossein Ghanaati Narges Zare Mehrjardi Saeed Kazemi Ashtiani Reza Malekzadeh Hossein Baharvand | 2007 | World Journal of Gastroenterology2007，13，24： | 74 |
| 2 | Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response显示文摘AIM: To investigate the co-incidence of apoptosis, autophagy, and unfolded protein response(UPR) in hepatitis B(HBV) and C(HCV) infected hepatocytes.METHODS: We performed immunofluorescence confocal microscopy on 10 liver biopsies from HBV and HCV patients and tissue microarrays of HBV positive liver samples. We used specific antibodies for LC3β, cleaved caspase-3, BIP(GRP78), and XBP1 to detect autophagy, apoptosis and UPR, respectively. AntiHCV NS3 and anti-HBs antibodies were also used to confirm infection. We performed triple blind counting of events to determine the co-incidence of autophagy(LC3β punctuate), apoptosis(cleaved caspase-3), and unfolded protein response(GRP78) with HBV and HCV infection in hepatocytes. All statistical analyses were performed using SPSS software for Windows(Version 16 SPSS Inc, Chicago, IL, United States). P-values < 0.05 were considered statistically significant. Statistical analyses were performed with Mann-Whitney test to compare incidence rates for autophagy, apoptosis, and UPR in HBV- and HCV-infected cells and adjacent noninfected cells.RESULTS: Our results showed that infection of hepatocytes with either HBV and HCV induces significant increase(P < 0.001) in apoptosis(cleavage of caspase-3), autophagy(LC3β punctate), and UPR(increase in GRP78 expression) in the HCV- and HBVinfected cells, as compared to non-infected cells of the same biopsy sections. Our tissue microarray immunohistochemical expression analysis of LC3β in HBV^(Neg) and HBV^(Pos) revealed that majority of HBVinfected hepatocytes display strong positive stainingfor LC3β. Interestingly, although XBP splicing in HBVinfected cells was significantly higher(P < 0.05), our analyses show a slight increase of XBP splicing was in HCV-infected cells(P > 0.05). Furthermore, our evaluation of patients with HBV and HCV infection based on stage and grade of the liver diseases revealed no correlation between these pathological findings and induction of apoptosis, autophagy, and UPR.CONCLUSION: The results of this study indicate that HCV and HBV infection activates apoptosis, autophagy and UPR, but slightly differently by each virus. Further studies are warranted to elucidate the interconnections between these pathways in relation to pathology of HCV and HBV in the liver tissue. | Behzad Yeganeh Adel Rezaei Moghadam Javad Alizadeh Emilia Wiechec Seyed Moayed Alavian Mohammad Hashemi Bita Geramizadeh Afshin Samali Kamran Bagheri Lankarani Martin Post Payam Peymani Kevin M Coombs Saeid Ghavami | 2015 | World Journal of Gastroenterology2015，21，47： | 13 |
| 3 | Laying hen performance,egg quality improved and yolk 5-methyltetrahydrofolate content increased by dietary supplementation of folic acid显示文摘This study was performed to evaluate the effect of folic acid(FA) on performance, egg quality and yolk5-methyltetrahydrofolate(5-MTHF) content. A total of 384 Hy-line W36 strain hens from 52 to 58 weeks of age were randomly assigned to 4 groups, and each group received one of following dietary treatments:0, 5.10 and 15 mg FA/kg diet. A completely randomized design was used. Egg production percentage, egg mass and egg weight were increased significantly(P < 0.05) and feed conversion ratio(FCR) was reduced significantly(P < 0.05) by increasing FA content in diets. No significant differences were detected among treatments on egg quality except for shell thickness. The dietary supplementations of laying hens diets with FA significantly increased yolk 5-MTHF content(P = 0.02). Overall, these data demonstrate that dietary supplementation with FA raised 5-MTHF content of yolk and productivity of egg production in laying hens. | Sattar Bagheri Hossein Janmohammadi Ramin Maleki Alireza Ostadrahimi Ruhollah Kianfar | 2019 | Animal Nutrition2019，，2： | 9 |
| 4 | Simultaneous determination of cysteamine and folic acid in pharmaceutical and biological samples using modified multiwall carbon nanotube paste electrode显示文摘一个碳浆糊电极(用户终端设备) 化学上与 multiwall 碳 nanotubes 修改了, ferrocene (FC ) 为 cysteamine (CA ) 和 folic 酸(FA ) 的踪迹数量的同时的决心被用作一个选择电气化学的传感器。这个修改电极为 CA 的阳极的氧化显示出很有效的 electrocatalytic 活动。CA 和 FA 的微分脉搏 voltammograms 的山峰水流在 0.7200 mol/L CA 和 5.0700 mol/L FA 的范围与他们的集中线性地增加了。为 CA 和 FA 的察觉限制分别地是 0.3 mol/L 和 2.0 mol/L。散开系数(D) 和转移系数() CA 也被决定。这些条件是足够的个别地并且同时允许 CA 和 FA 的决心。 | Ali Taherkhani Hassan Karimi-Maleh Ali A.Ensafi Hadi Beitollahi Ahmad Hosseini Mohammad A.Khalilzadeh Hassan Bagheri | 2012 | Chinese Chemical Letters2012，23，2： | 6 |
| 5 | 第二相粒径和振动对FSP制备AZ91/SiC表面复合层的影响显示文摘采用改进的搅拌摩擦加工方法(FSP)加工AZ91镁合金试样。这种新方法称为“振动搅拌摩擦加工方法(FSVP)”。SiC纳米颗粒作为第二相粒子,利用FSP和FSVP制备合金的表面复合层,研究不同粒径(30 nm和300 nm)的SiC强化颗粒对复合材料表面不同性能的影响。结果表明,采用FSVP工艺能细化材料的显微组织,提高材料的硬度、延展性和强度等力学性能。粒径为30 nm的增强颗粒对复合材料显微组织和力学性能的影响大于粒径为300 nm的增强颗粒。振动频率越高,FSV试样的力学性能和显微组织越好;当FSV振动频率为50和25 Hz时,搅拌区硬度值分别约为157和116 MPa。 | Behrouz BAGHERI Mahmoud ABBASI Amin ABDOLLAHZADEH Seyyed Ehsan MIRSALEHI | 2020 | Transactions of Nonferrous Metals Society of China2020，30，4： | 6 |
| 6 | Effects of intermediate Ni layer on mechanical properties of Al–Cu layered composites fabricated through cold roll bonding显示文摘Layered composites have attracted considerable interest in the recent literature on metal composites. Their mechanical properties depend on the quality of the bonding provided by the intermediate layers. In this study, we analyzed the mechanical properties and bond strengths provided by the nickel layer with respect to its thickness and nature(either powder or coating). The results suggest that bond strength decreases with an increase in the content of nickel powder. At 0.3 vol% of nickel coating, we found the nature of nickel to be less efficient in terms of bond strength. A different picture arose when the content of nickel was increased and the bond strength increased in nickel coated samples. In addition, the results demonstrate that mechanical properties such as bend strength are strongly dependent on bond strength. | Ali Shabani Mohammad Reza Toroghinejad Alireza Bagheri | 2018 | International Journal of Minerals,Metallurgy and Materials2018，25，5： | 5 |
| 7 | COVID-19 infection and liver injury:Clinical features,biomarkers,potential mechanisms,treatment,and management challenges显示文摘It is hypothesized that liver impairment caused by coronavirus disease 2019(COVID-19)infection might play a central role in severe clinical presentations.Liver injury is closely associated with severe disease and,even with antiviral drugs,have a poor prognosis in COVID-19 patients.In addition to the common hepatobiliary disorders caused by COVID-19,patients with pre-existing liver diseases demand special considerations during the current pandemic.Thus,it is vital that upon clinical presentation,patients with concurrent pre-existing liver disease associated with metabolic dysfunction and COVID-19 be managed properly to prevent liver failure.Careful monitoring and early detection of liver damage through biomarkers after hospitalization for COVID-19 is underscored in all cases,particularly in those with pre-existing metabolic liver injury.The purpose of this study was to determine most recent evidence regarding causality,potential risk factors,and challenges,therapeutic options,and management of COVID-19 infection in vulnerable patients with pre-existing liver injury.This review aims to highlight the current frontier of COVID-19 infection and liver injury and the direction of liver injury in these patients. | Gholam Reza Sivandzadeh Hassan Askari Ali Reza Safarpour Fardad Ejtehadi Ehsan Raeis-Abdollahi Armaghan Vaez Lari Mohammad Foad Abazari Firoozeh Tarkesh Kamran Bagheri Lankarani | 2021 | World Journal of Clinical Cases2021，9，22： | 5 |
| 8 | Magnetic metal organic framework for pre-concentration of ampicillin from cow milk samples显示文摘The aim of this study is a present of a simple solvothermal synthesis approach to preparation of Cu-based magnetic metal organic framework(MMOF)and subsequently its application as sorbent for ultrasound assisted magnetic solid phase extraction(UAMSPE)of ampicillin(AMP)from cow milk samples prior to high performance liquid chromatography-Ultraviolet(HPLC-UV)determination.Characteristics of prepared MMOF were fully investigated by different techniques which showed the exclusive properties of proposed sorbent in terms of proper functionality,desirable magnetic property and also high specific surface area.Different influential factors on extraction recovery including sorbent dosage,ultrasonic time,washing solvent volume and eluent solvent volume were assessed using central composite design(CCD)based response surface methodology(RSM)as an operative and powerful optimization tool.This is the first report for determination of AMP using MMOF.The proposed method addressed some drawbacks of other methods and sorbents for determination of AMP.The presented method decreases the extraction time(4 min)and also enhances adsorption capacity(250 mg/g).Moreover,the magnetic property of presented sorbent(15 emu/g)accelerates the extraction process which does not need filtration,centrifuge and precipitation procedures.Under the optimized conditions,the proposed method is applicable for linear range of 1.0-5000.0 μg/L with detection limit of 0.29 μg/L,satisfactory recoveries(≥95.0%)and acceptable repeatability(RSD less than 4.0%).The present study indicates highly promising perspectives of MMOF for highly effective analysis of AMP in complicated matrices. | Ahmad Reza Bagheri Mehrorang Ghaedi | 2020 | Journal of Pharmaceutical Analysis2020，10，4： | 5 |
| 9 | 无效医疗:全球审视显示文摘一般来说,医生选择针对临终患者的医疗决策,尤其是在做出无效医疗的决定时,会考虑到人类死亡的必然性、医学局限性、健康资源匮乏以及多元的社会文化因素。无效医疗来源于医学干预的不恰当应用,即这种干预不会对患者产生明显的效果。无效医疗是一个很古老的概念,在医学领域中关于它的使用已有很长的历史。在日常的临床实践中,医生在做出无效治疗的决定时承担了很大的压力,并且在一些案例中,医疗机构和患者家属之间对于无效治疗的决定也存在很多分歧。从整体的角度阐述无效医疗这一问题以及不同国家的医疗机构如何处理无效医疗。通过回顾不同的政策选择,提议制定无效政策来帮助医生、患者及其家属以决定是否采用无效治疗,减少分歧。 | Alireza Bagheri 王德顺 | 2014 | 医学与哲学(A)2014，35，12： | 5 |
| 10 | B12N12纳米笼:潜在的二氧化氮检测传感器显示文摘利用密度泛函理论通过计算吸附能量、HOMO/LUMO能隙变化、电荷转移、结构扭曲等研究二氧化氮分子在B12N12纳米笼的吸附.此外,通过计算B12N12的电子结合能、Gibbs自由能、态密度和分子表面的静电势研究其稳定性和其它特性.B12N12纳米笼吸附二氧化氮显示三种构型.B12N12团簇的HOMO/LUMO能隙变化对二氧化氮分子的存在非常敏感,从自由团簇的6.84eV降为N02/团簇稳定团簇的3.23eV.团簇的导电性被极大地提高,表明B12N12纳米簇可能是潜在的二氧化氮气体分子检测传感器. | Javad Beheshtian Mohammad Kamfiroozi Zargham Bagheri AliAhmadi Peyghan | 2012 | Chinese Journal of Chemical Physics2012，25，1： | 4 |
| 11 | 振动搅拌摩擦焊镁合金动态再结晶过程的模拟与实验研究显示文摘采用二维元胞自动机(CA)模型分析机械振动对AZ91合金在搅拌摩擦焊(FSW)过程中组织演变的影响。将模拟结果,即晶粒拓扑结构、粒度分布、平均晶粒度以及动态再结晶(DRX)分数与实测数据进行比较。结果显示,有限元分析结果与实验数据具有充分的相似性,CA方法可用于搅拌摩擦焊AZ91合金组织演变的分析。与FSW相比,振动搅拌摩擦焊(FSVW)处理的样品中位错密度更高,形核和晶粒长大也更快。对FSVW过程中不同振动频率下的晶粒度改变和DRX现象经过详细模拟后发现,振动使形核开始时间提前,随着振动频率的提高,孕育期和再结晶的比例降低。 | Mahmoud ABBASI Behrouz BAGHERI Farzaneh SHARIFI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，9： | 4 |
| 12 | Prediction of plastic zone size around circular tunnels in non-hydrostatic stress field显示文摘This paper discusses the calculation of plastic zone properties around circular tunnels to rock-masses that satisfy the Hoek–Brown failure criterion in non-hydrostatic condition,and reviews the calculation of plastic zone and displacement,and the basis of the convergence–confinement method in hydrostatic condition.A two-dimensional numerical simulation model was developed to gain understanding of the plastic zone shape.Plastic zone radius in any angles around the tunnel is analyzed and measured,using different values of overburden(four states)and stress ratio(nine states).Plastic zone radius equations were obtained from fitting curve to data which are dependent on the values of stress ratio,angle and plastic zone radius in hydrostatic condition.Finally validation of this equation indicate that results predict the real plastic zone radius appropriately. | Behnam Bagheri Fazlollah Soltani Hamid Mohammadi | 2014 | International Journal of Mining Science and Technology2014，24，1： | 3 |
| 13 | Digital Soil Mapping Using Artificial Neural Networks and Terrain-Related Attributes显示文摘Detailed soil surveys involve costly and time-consuming work and require expert knowledge. Since soil surveys provide information to meet a wide range of needs, new methods are necessary to map soils quickly and accurately. In this study, multilayer perceptron artificial neural networks(ANNs) were developed to map soil units using digital elevation model(DEM) attributes. Several optimal ANNs were produced based on a number of input data and hidden units. The approach used test and validation areas to calculate the accuracy of interpolated and extrapolated data. The results showed that the system and level of soil classification employed had a direct effect on the accuracy of the results. At the lowest level, smaller errors were observed with the World Reference Base(WRB)classification criteria than the Soil Taxonomy(ST) system, but more soil classes could be predicted when using ST(7 soils in the case of ST vs. 5 with WRB). Training errors were below 11% for all the ANN models applied, while the test error(interpolation error) and validation error(extrapolation error) were as high as 50% and 70%, respectively. As expected, soil prediction using a higher level of classification presented a better overall level of accuracy. To obtain better predictions, in addition to DEM attributes, data related to landforms and/or lithology as soil-forming factors, should be used as ANN input data. | Mohsen BAGHERI BODAGHABADI José Antonio MARTINEZ-CASASNOVAS Mohammad Hasan SALEHI Jahangard MOHAMMADI Isa ESFANDIARPOOR BORUJENI Norair TOOMANIAN Amir GANDOMKAR | 2015 | Pedosphere2015，25，4： | 3 |
| 14 | Microstructure and mechanical characteristics of AA6061-T6 joints produced by friction stir welding,friction stir vibration welding and tungsten inert gas welding:A comparative study显示文摘This study compared the microstructure and mechanical characteristics of AA6061-T6 joints produced using friction stir welding(FSW),friction stir vibration welding(FSVW),and tungsten inert gas welding(TIG).FSVW is a modified version of FSW wherein the joining specimens are vibrated normal to the welding line during FSW.The results indicated that the weld region grains for FSVW and FSW were equiaxed and were smaller than the grains for TIG.In addition,the weld region grains for FSVW were finer compared with those for FSW.Results also showed that the strength,hardness,and toughness values of the joints produced by FSVW were higher than those of the other joints produced by FSW and TIG.The vibration during FSW enhanced dynamic recrystallization,which led to the development of finer grains.The weld efficiency of FSVW was approximately 81%,whereas those of FSW and TIG were approximately 74%and 67%,respectively. | Behrouz Bagheri Mahmoud Abbasi Amin Abdollahzadeh | 2021 | International Journal of Minerals,Metallurgy and Materials2021，28，3： | 3 |
| 15 | Preparation of a novel, efficient, and recyclable magnetic catalyst,γ-Fe2O3@HAp-Ag nanoparticles, and a solvent- and halogen-free protocol for the synthesis of coumarin derivatives显示文摘In this protocol, Ag supported on the hydroxyapatite-core–shell magnetic γ-Fe_2O_3nanoparticles(γFe_2O_3@HAp-Ag NPs) as a novel, efficient, and magnetically recyclable catalyst is synthesized, and characterized by transmission electron microscopy(TEM), scanning electron microscopy(SEM), Fourier transform infrared spectroscopy(FT-IR), X-ray diffraction(XRD), and vibrating sample magnetometry(VSM). The use of the catalyst is described in the synthesis of coumarin derivatives by the Pechmann condensation of various phenols with β-ketoesters under solvent- and halogen-free conditions at 80℃.This novel and inexpensive method offers advantages, such as recyclability simple experimental protocol, short reaction time, minimal work-up procedure, and excellent yields of products, together with desirable, eco-friendly, green aspects by avoiding toxic elements and solvents, and ease of recovery from the reaction mixture using an external magnet. | Zahra Abbasi Sobhan Rezayati Maryam Bagheri Rahimeh Hajinasiri | 2017 | Chinese Chemical Letters2017，28，1： | 3 |
| 16 | Randomized placebo‐controlled trial of mesenchymal stem cell transplantation in decompensated cirrhosis显示文摘 | Mehdi Mohamadnejad Kamran Alimoghaddam Mohammad Bagheri Mandana Ashrafi Leila Abdollahzadeh Shahram Akhlaghpoor Maryam Bashtar Ardeshir Ghavamzadeh Reza Malekzadeh | 2013 | Liver Int2013，，10： | 3 |
| 17 | Development of AZ91/SiC surface composite by FSP:effect of vibration and process parameters on microstructure and mechanical characteristics显示文摘A surface composite layer enhances the mechanical characteristics of a surface while retaining the properties of the base material.Friction stir processing(FSP)is a method for forming surface metal matrix composites(SMMCs)that reinforce a surface with particles.In the current study,a new method entitled friction stir vibration processing(FSVP)was applied to form SMMCs on the surface of AZ91 magnesium alloy with SiC particles as the reinforcing particles.Contrary to FSP,in FSVP,the workpiece was vibrated normal to the processing line while the tool rotated and traversed.The microstructure and mechanical properties of friction stir(FS)and friction stir vibration(FSV)processed specimens were evaluated.Additionally,the effects of vibration frequency and process parameters on different characteristics of FS and FSV processed specimens were studied.The results showed that the stir zone grains for FSV processed specimens were finer than those for FS processed specimens,and the second phase particles(SiC particles)had a more homogenous distribution in the former specimens than in the latter specimens.This was related to the effect of workpiece vibration during FSVP,which increased the material deformation and led to enhanced dynamic recrystallization and the breakdown of agglomerated SiC particles.The results indicated that the stir zone grain size decreased,and the distribution homogeneity of the SiC particles increased as vibration frequency increased.It was also observed that the stir zone grain size increased,and the mechanical properties of the processed specimens decreased as tool rotation speed increased. | Behrouz Bagheri Mahmoud Abbasi | 2020 | Advances in Manufacturing2020，8，1： | 3 |
| 18 | 应用振动提高搅拌摩擦加工效率(英文)显示文摘搅拌摩擦加工(FSP)是一种处理金属表面的固态改性方法。在此过程中,由于非自耗刀具的旋转和来回移动,使金属表面组织细化、力学性能提升。提高FSP 效率的方法较多,本研究中采用的是一种叫振动搅拌摩擦加工(FSVP)的新方法。在此方法中,金属工件在FSP 过程中与加工线垂直振动。分析比较FSP 法和FSVP 法加工的Al5052 合金试样的显微组织和力学性能,包括硬度、极限抗拉强度(UTS)和伸长率。结果表明,采用FSVP 后,振动可使材料的晶粒尺寸减小约33%,极限抗拉强度和硬度提高约7%。这与振动作用下金属表面材料的应变增强有关。应变增加导致位错密度增加,动态再结晶使大角度晶界进一步发育。结果还表明,FSV 加工试样的极限抗拉强度和伸长率均随振动频率的增加而增加。 | M. ABBASI M. GIVI B. BAGHERI | 2019 | Transactions of Nonferrous Metals Society of China2019，29，7： | 2 |
| 19 | Textural, color and sensory attributes of peanut kernels as affected by infrared roasting method显示文摘Roasting is one of the widespread methods for processing of nuts that significantly enhances the flavor,color,texture and appearance of products.In this research,the response surface methodology was used to optimize the roasting process over a range of infrared power(250–450 W)and roasting times(10–30 min).The moisture content,color parameters(L*,a*,b*and total color difference(DE)),textural characteristics(hardness and compressive energy),energy consumption and sensory evaluation(total acceptation)were determined after roasting and modeled by response surface methodology(RSM).Increasing in roasting IR power and time caused increasing in the energy consumption,a*,b*and DE values.The L*value,moisture content,hardness and compressive energy also decreased with increasing roasting IR power and time.The full quadratic model developed by RSM adequately described the changes in the b*value,moisture content and hardness.The result of RSM analysis showed that all color and textural parameters could be used to monitor the roasting of peanut kernels in an infrared roaster,while application of RSM for developing a predictive model that described the total acceptance changes during roasting of peanut kernels was not successful.To obtain the desired color,moisture,texture and acceptation,the optimum roasting range for production of snack was determined as 370W for 20 min. | Hadi Bagheri Mahdi Kashaninejad Aman Mohammad Ziaiifar Mehran Aalami | 2019 | Information Processing in Agriculture2019，6，2： | 2 |
| 20 | 二氧化锡纳米粒子催化四组分Hantzsch缩合合成多氢喹啉衍生物(英文)显示文摘Tin dioxide (SnO2 ) nanoparticles efficiently catalyzed unsymmetrical four-component Hantzsch condensations of various aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate to form polyhydroquinoline derivatives in excellent yields. This novel method offers several advantages over the traditional method of synthesizing these compounds, including safety, mild conditions, short reaction times, high yields, and an easy workup. | Seyed Mohammad VAHDAT Fereshteh CHEKIN Mehdi HATAMI Maryam KHAVARPOUR Saeed BAGHERY Ziba ROSHAN‐KOUHI | 2013 | 催化学报2013，34，4： | 2 |
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