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103篇 您的检索式:作者名="BISSONNETTE B"
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15-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘象 5-methylcytosine (5mC ) 和 5-hydroxymethylcytosine (5hmC ) 那样的 DNA 修正是知道在哺乳动物影响全球基因表示的 epigenetic 标记。在人的染色体,与基因表示的靠近的关联和高化学的稳定性给他们的流行,这些 DNA epigenetic 标记能为癌症用作理想的 biomarkers 诊断。利用一种高度敏感、选择的化学标记技术,我们这里报导在传播没有房间的 DNA ( cfDNA )并且在从最近与 colorectal 诊断的 260 个病人的一个队收集的配对的肿瘤和邻近的纸巾的 genomic DNA ( gDNA )的 5hmC 的染色体宽的介绍,胃,胰腺,从 90 个健康个人的肝或甲状腺癌症和正常纸巾。5hmC 主要在与开的染色质和容许的 histone 修正重合的 transcriptionally 活跃的区域被散布。柔韧的联系癌症的 5hmC 签名在 cfDNA 被识别为特定的癌症类型是特征的。传播 cfDNA 的 5hmC 底 biomarkers colorectal 和胃的癌症是高度预兆的并且比常规 biomarkers 优异并且比得上从织物活体检视的 5hmC biomarkers。因此,这新策略能从血样品的分析为癌症的诊断和预后导致有效、最低限度地侵略的方法的发展。Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu 2017Cell Research2017,27,10:30
2Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis显示文摘Liu Weicheng Chen Yunzi Golan Maya Aharoni Annunziata Maria L Du Jie Dougherty Urszula Kong Juan Musch Mark Huang Yong Pekow Joel Zheng Changqing Bissonnette Marc Hanauer Stephen B Li Yan Chun 2013Journal of Clinical Investigation2013,,9:2
3Capnometry and the paediatric laryngeal mask airway 显示文摘Spahr-Schopfer I A Bissonnette B Hartley E J 1993Can J Anesth1993,40,5:1
4Peroperative risks in cerebral aneurysm surgery 显示文摘Mustaki JP Bissonnette B Archer D 1996Ann Fr Anesth Reanim1996,15,3:1
5Influence of key parameters on drying shrinkage of cementitious mate- rials显示文摘Bissonnette B Pierre P Pigeon M 2003Cement and Structure2003,29,10:1
6Hemodynamic and respiratory effect of pediatric urological laparoscopic surgery:a retrospective study显示文摘Halachmi S EI-Ghoneimi A Bissonnette B 2003J Urol2003,170,42:1
7Intraoperative temperature monitoring sites in infants and children and the effect of inspired gas warming on esophageal temperature显示文摘Bissonnette B Sessler DI Laflamme P 1989J Anesth Analg1989,69,2:1
8Effects of temperature and haematocrit on the relationships between blood flow velocity and blood flow in a vessel of fixed diameter显示文摘Paut O Bissonnette B 2002British Journal of Anaesthesia2002,88,2:1
9Influence of key parameters on drying shrinkage of cementitious materials 显示文摘Bissonnette B Pierre P Pigeon M 2003Cement and Structure2003,33,:1
10Influence of Key Parameters on Drying Shrinkage of Cementitious Materials 显示文摘Bissonnette B Pierre P Pigeon M 1999Cement and Concrete Research1999,29,10:1
11Duchenne muscular dystrophy: An old anesthesia problem revisited显示文摘Hayes J Veyckemans F Bissonnette B 2008Paediatr Anaesth2008,18,2:1
12Hemodynamic and respiratary effect of pediatric urological laparoscopic surgery:a retrospective study显示文摘Halachmi S Ghoneimi AE Bissonnette B 2003J Urol2003,170,4:1
13Capnometry and the paediatric laryngeal mask airway显示文摘Spahi-schopfer IA Bissonnette B Hartley EJ 2008Can J Anaseth2008,40,:1
14Influence of key parameters on drying shrinkage of cementitious materials显示文摘BISSONNETTE B PIERRE P PIGEON M 1999Cement and Concrete Research1999,29,10:1
15Influence of key pa- rameters on drying shrinkage of cementitious materials 显示文摘BISSONNETTE B PIERRE P PIGEON M 1999Ce- ment and Concrete Research1999,29,10:1
16Airway management in children: ultrasonography assess- ment of tracheal intubation in real time 显示文摘Marciniak B Fayoux P Hebrard A Bissonnette B 2009Anesth Analg2009,108,2:1
17Hemodynamic and respiratory effect of pediatric urological laparoscopic surgery :a retrospective study 显示文摘Halaehmi Si El-Ghoneimi A Bissonnette B 2003J Urol2003,170,:1
18Intraoperative tem- perature monitoring sites in infants and children and the effect of inspired gas warming on esophageal temperature显示文摘Bissonnette B Sessler DI LaFlamme P 1989Anesth Analg1989,69,:1
199-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoie acid receptor and retinoid X receptor activation 显示文摘BISSONNETTE R P BRUNNER T LAZARCHIK S B 1995Mol Cell Biol1995,15,10:1
20Therapeutic Hypothermia显示文摘Arrica M Bissonnette B 2007Cardiothorac Vasc Anesth2007,,1:1
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