|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 巨噬细胞中缺氧诱导因子1α表达促进动脉粥样硬化的发展显示文摘粥样硬化病变包含缺氧区域,但缺氧病理生理的重要性未知。缺氧诱导因子1a(hypoxia-induciblefactor-1α,HIF-1α)是细胞对低氧反应的关键转录因子。研究人员对HIF-1α在巨噬细胞促进小鼠动脉粥样硬化的生物学效应方面进行调查和验证。 | 刘莉 叶鹏 Aarup A Pedersen TX Junker N Christoffersen C Bartels ED Madsen M Nielsen CH Nielsen LB | 2016 | 中华高血压杂志2016，24，9： | 3 |
| 2 | Changes in myocardial collagen content before and after left ventricular assist device application in dilated cardiomyopathy显示文摘Background The purposes of this study were to confirm the changes in myocardial collagen level after left ventricular assist device (LVAD) support in dilated cardiomyopathy (DCM), find the relation between these changes and prognosis, an d test a practical method to assess the level of myocardial collagen.Methods Left ventricular samples were collected from DCM patients with different prognosis (transplanted group n=8, weaning group n=10) at the time when the LV ADs were implanted and again during cardiac transplantation (n=8). The level of neutral salt soluble collagen (NSC) and acid soluble collagen (ASC) was measured by Sircol collagen assay, and that of total collagen and insoluble collagen (ISC) by quantification of hydroxyproline (Hyp). Serum samples were collected from a portion of these patients (transplanted group, n=6; weaning group n=7) at the time the LVADs were implanted, 1 month after implantation and on explantation. Circulating concentration of carboxy-terminal propeptide of type Ⅰ procollagen (PⅠCP), amino-terminal propeptide of type Ⅰ procollagen (PⅠNP), amino-terminal propeptide of type Ⅲ procollagen (PⅢNP) and type Ⅰ collagen telopeptide (ⅠCTP) were measured by the equilibrium type radioimmunoassay. Results Before LVAD implantation the level of NSC and ISC in th e weaning group was higher but ASC in the transplanted group was lower than in the control s (P<0.05). After LVAD support, the level of total collagen was higher, but ASC was also lower in the transplanted group than in the controls (P<0.05). In comparison of the pre- and po st-LVAD subgroups of the transplanted and weaning groups, all collagen fraction levels before LVAD implantation were lower in the transplanted group than in the weaning group (P<0.05); but this difference disappeared after LVAD support. Comparison of the pre- and post-LVAD subgroups of the transplanted group showed increased le vel of NSC and total collagen after LVAD support. The changes of serum p eptide concentration showed that PⅢNP increased constantly in the transplanted group, but PⅠCP and PⅠNP increased in the weaning group after LVAD implantation. Conclusions The changes in myocardial collagen level as a sign of myocardial interstitial remodeling in DCM are not involved with total collagen b ut invalved with collagen fractions, and they are related to prognosis. The changes of myocardial c ollagen content and serum procollagen peptide after LVAD support can be regarded as an expression of the reverse of maladaptive myocardial interstitial remodeling. | 梁红 Johannes Müller 翁渝国 Gerd Wallukat 付平 林汉生 Sabina Bartel Christoph Knosalla Reinhard Pregla Roland Hetzer | 2004 | Chinese Medical Journal2004，，3： | 3 |
| 3 | Interhem ispheric subdural hematoma in adults case reports and a review of the literature 显示文摘 | BARTELS R H VERHAGEN W I PRICK M J | 1995 | Neurosurgery1995，36，6： | 1 |
| 4 | A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD 显示文摘 | Fujihara M Bartels E Nielsen LB Handa JT | 2009 | Exp Eye Res2009，88，6： | 1 |
| 5 | dGEMRICas a tool for measuring changes in cartilage quality followinghigh tibial osteotomy : a feasibility study显示文摘 | RUTGERS M BARTELS LW TSUCHIDA AI | 2012 | Osteoarthr Cartil2012，20，10： | 1 |
| 6 | Poststroke depression: is there a pathoanatomic correlate for depression in the postacute stage of stroke 显示文摘 | Bartels L Schumacher M | 1995 | Stroke1995，26，5： | 1 |
| 7 | Antiquity of microRNAs and their targets in land plants显示文摘 | Axtell M J Bartel D P | 2005 | Plant Cell2005，17，： | 1 |
| 8 | Th1 and Th2 type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts 显示文摘 | Teran LM Mochizuki M Bartels J | 1997 | Am J Respir Cell Mol Biol1997，20，： | 1 |
| 9 | Computational identification of plant microRNAs and their targets,including a stress-induced miRNA显示文摘 | Jones-Rhoades M W Bartel D P | 2004 | Mol Cell2004，14，6： | 1 |
| 10 | Recombinant hu- man erythropoietin delays loss of gray matter in chronic schizo- phrenia显示文摘 | Wtistenberg T Begemann M Bartels C | 2011 | Mol Psychiatry2011，16，1： | 1 |
| 11 | Estrogen receptor-[alpha] signaling in osteoblast progenitors stimulates cortical bone accrual显示文摘 | Almeida Maria Iyer Srividhya Martin-Millan Marta Bartell Shoshana M Han Li Ambrogini Elena Onal Melda Xiong Jinhu Weinstein Robert S Jilka Robert L O’Brien Charles A Manolagas Stavros C | 2013 | Journal of Clinical Investigation2013，，1： | 1 |
| 12 | Anesthesia and cognitive per-formance in children:no evidence for a causal relationship显示文摘 | Bartels M Althoff RR Boomsma DI | 2009 | Twin Res Hum Genet2009，12，： | 1 |
| 13 | The problem of surface damage in polyethylene total knee components 显示文摘 | WRIGHT T M BARTEL D L | 1986 | Clin Orthop & Relat Res1986，205，4： | 1 |
| 14 | Postirradi- ation aging affects stress and strain in polyethylene compo- nents 显示文摘 | KURTZ S M BARTEL D L RIMNAC C M | 1998 | Clin Orthop Relat Res1998，350，： | 1 |
| 15 | Overview of the MELD score and the UNOS adult liver allocation system显示文摘 | Martin A P Bartels M Hauss J | 2007 | Transplant Proc2007，39，10： | 1 |
| 16 | Characteristics of Neospora eaninum-assoeiated abortion storms in dairy herds in the Netherlands (1995 to 1997) 显示文摘 | Wouda W Bartels C J M Moen A R | 1999 | Theriogenology1999，52，2： | 1 |
| 17 | MicroRNAs and their regulatory roles in plants 显示文摘 | JONES-RHOADES M W BARTEL D P BARTEL B | 2006 | Annu Rev Plant Bi- ol2006，，57： | 1 |
| 18 | Static analysis for extractingpermission checks of a large scale framework: the challenges and so-lutions for analyzing Android 显示文摘 | Bartel A Klein J Monperrus M | 2014 | IEEE Trans on Software Engi-neering2014，40，6： | 1 |
| 19 | Changes in quality of life after renal transplantation显示文摘 | OVERBECK I BARTELS M DECKER O | 2005 | Transplant Proc2005，37，3： | 1 |
| 20 | The norm activationmodel : An exploration of the functions of anticipated pride and guilt inpro-environmental behavior显示文摘 | ONWEZEN M C ANTONIDESG BARTELS J | 2013 | Journal of Economic Psychology2013，39，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员