|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Primary and secondary hyperoxaluria: Understanding the enigma显示文摘Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolism due to defective enzyme activity. In contrast, secondary hyperoxaluria is caused by increased dietary ingestion of oxalate, precursors of oxalate or alteration in intestinal microflora. The disease spectrum extends from recurrent kidney stones, nephrocalcinosis and urinary tract infections to chronic kidney disease and end stage renal disease. When calcium oxalate burden exceeds the renal excretory ability, calcium oxalate starts to deposit in various organ systems in a process called systemic oxalosis. Increased urinary oxalate levels help to make the diagnosis while plasma oxalate levels are likely to be more accurate when patients develop chronic kidney disease. Definitive diagnosis of primary hyperoxaluria is achieved by genetic studies and if genetic studies prove inconclusive, liver biopsy is undertaken to establish diagnosis. Diagnostic clues pointing towards secondary hyperoxaluria are a supportive dietary history and tests to detect increased intestinal absorption of oxalate. Conservative treatment for both types of hyperoxaluria includes vigorous hydration and crystallization inhibitors to decrease calcium oxalate precipitation. Pyridoxine is also found to be helpful in approximately 30% patients with primary hyperoxaluria type 1. Liver-kidney and isolated kidney transplantation are the treatment of choice in primary hyperoxaluria type 1 and type 2 respectively. Data is scarce on role of transplantation in primary hyperoxaluria type 3 where there are no reports of end stage renal disease so far. There are ongoing investigations into newer modalities of diagnosis and treatment of hyperoxaluria. Clinical differentiation between primary and secondary hyperoxaluria and further between the types of primary hyperoxaluria is very important because of implications in treatment and diagnosis. Hyperoxaluria continues to be a challenging disease and a high index of clinical suspicion is often the first step on the path to accurate diagnosis and management. | Bhavna Bhasin Hatice Melda ürekli Mohamed G Atta | 2015 | World Journal of Nephrology2015，4，2： | 13 |
| 2 | Evaluation of leukocyte esterase and nitrite strip tests to detect spontaneous bacterial peritonitis in cirrhotic patients显示文摘AIM: To investigate the diagnostic eff icacy of leukocyte esterase and nitrite reagent strips for bedside diagnosis of spontaneous bacterial peritonitis (SBP). METHODS: A total of 63 consecutive patients with cirrhotic ascites (38 male, 25 female) tested between April 2005 and July 2006 were included in the study. Bedside reagent strip testing was performed on ascitic ? uid and the results compared to manual cell counting and ascitic fluid culture. SBP was defined as having a polymorphonuclear ascites count of ≥ 250/mm3. RESULTS: Fifteen samples showed SBP. The sensitivity, specificity, positive and negative predictive values of the leukocyte esterase reagent strips were; 93%, 100%, 100%, and 98%, respectively. The sensitivity, specifi city, positive and negative predictive value of the nitrite reagent strips were 13%, 93%, 40%, and 77%, respectively. The combination of leukocyte esterase and nitrite reagents strips did not yield statistically signif icant effects on diagnostic accuracy. CONCLUSION: Leukocyte esterase reagent strips may provide a rapid, bedside diagnostic test for SBP. | Serkan Torun Enver Dolar Yusuf Yilmaz Murat Keskin Murat Kiyici Melda Sinirtas Emre Sarandol Selim Gurel Selim Giray Nak Macit Gulten | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 3 | RCEP背景下中国对外直接投资在印尼的潜力和挑战显示文摘为推动中国与印尼经贸合作,加强“一带一路”倡议同印尼发展战略对接,发挥双方经济互补优势,通过文献阅读法和统计分析法梳理了印尼的投资环境、外来投资区位结构,中国对印尼直接投资的区位结构和海外园区分布;通过回归模型,分析投资环境对中国在印尼直接投资的影响,探索RCEP背景下中国在印尼直接投资面临的潜力和挑战。研究认为,中国在印尼的直接投资面临经济发展水平、投资便利度、政府影响和人力资源等因素共同影响着中国在印尼的对外直接投资规模;经济发展水平、投资便利度、政府影响、人力资源等投资环境是制约印尼吸引外国投资和发展经济的外在阻碍,行政管理体制是制约印尼经济发展的内在因素;如何处理好外来产业和本土产业的关系是印尼未来发展所面临的重大挑战。研究表明,中国和印尼要充分利用RCEP签署带来的巨大政策红利,利用好两国已有的合作机制和平台,鼓励中国企业积极对接相关产业合作园区,深度参与印尼海洋经济、食品制造、能源经济等重点产业的投资开发,形成较多互补性和较少竞争性的中印尼经贸关系,实现国家间政治、经济关系的飞跃发展,外贸与投资领域的新突破。 | 汪涛 王玥 AGUS SUPRIYADI MELDA RIA JUWITA | 2022 | 长安大学学报(社会科学版)2022，24，5： | 2 |
| 4 | Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol显示文摘 | Delanian S Balla Meldas S Lefaix JL | 1999 | J Clin Oncol1999，17，10： | 1 |
| 5 | Energy and exergy analyses of an experimental open-cycle desiccant cooling system 显示文摘 | Mehmet Kanoglu Melda Ozdinc Ca | 2004 | Appl Thermal Eng2004，，24： | 1 |
| 6 | Estrogen receptor-[alpha] signaling in osteoblast progenitors stimulates cortical bone accrual显示文摘 | Almeida Maria Iyer Srividhya Martin-Millan Marta Bartell Shoshana M Han Li Ambrogini Elena Onal Melda Xiong Jinhu Weinstein Robert S Jilka Robert L O’Brien Charles A Manolagas Stavros C | 2013 | Journal of Clinical Investigation2013，，1： | 1 |
| 7 | Energy and exergy analyses of an experimental open-cycle desiccant cooling system 显示文摘 | Mehmet Kanoglu Melda Ozdinc Carpinlioglu Murtaza Yildirim | 2004 | Applied Thermal Engineering2004，24，： | 1 |
| 8 | A Secure Communication Game with a Relay Helping the Eavesdropper显示文摘 | Melda Yuksel LIU Xi Elza Erkip | 2011 | IEEE Transactions on Information Theory Forensics and Security2011，6，03： | 1 |
| 9 | Energy and exergy analysis of an experimental open cycle desiccant cooling system 显示文摘 | Mehmet Kanoglu Melda Ozdinc | 2004 | Applied Thermal Engineering2004，24，56： | 1 |
| 10 | A critical review on pulsatile pipe flow studies directing towards future research topics 显示文摘 | MELDA O MEHMET Y | 2001 | Flow Measurement and Instrumentation2001，，12： | 1 |
| 11 | Assessment and Comparison of Anterior Chamber Dimensions Using Various Imaging Techniques显示文摘 | Dinc Umut Asli Oncel Banu Gorgun Ebru Yenerel Melda Nursal Alimgil Levent | 2010 | Ophthalmic Surgery Lasers and Imaging2010，，1： | 1 |
| 12 | Regulation of barley miRNAs upon dehydration stress correlated with target gene expression 显示文摘 | Melda K Turgay U Hikmet B | 2010 | FunctIntegr Genomics2010，34，： | 1 |
| 13 | miRNA expression patterns of Triticum dicoccoides in response to shock drought stress 显示文摘 | Melda K Stuart J L Hikmet B | 2010 | Planta2010，35，12： | 1 |
| 14 | Multiple-Antenna Cooperative Wireless Systems:A Diversity-Multiplexing Tradeoff Perspective显示文摘 | Melda Yuksel Elza Erkip | | 0，，10： | 1 |
| 15 | Multiple-antenna cooperative wireless systems : a diversity-multiplexing tradeoff perspective 显示文摘 | Melda Y Elza E | 2007 | IEEE Transactions on Information Theory2007，53，10： | 1 |
| 16 | Energy and exergy analyses of an experimental open cycle desiccant cooling system显示文摘 | Mehmet Kanoglu Melda Ozdinc Ca | 2004 | App l Thermal Eng2004，，24： | 1 |
| 17 | 显示文摘 | Melda Akbin Bahar Giirkaya Basoar Uyar | 2012 | New Bio-technology2012，29，： | 1 |
| 18 | Garlic, hypertension and patient education 显示文摘 | Mustafa Capraz Melda Dilek Tekin Akpolat | 2007 | International Journal of Cardiology2007，121，： | 1 |
| 19 | A Critical review on pulsatile pipe flow studies directing towards future research topics显示文摘 | Mehmet Ya(e)ar Gündogˇdu | 2001 | Flow Measurement and Instrumentation2001，，12： | 1 |
| 20 | Electrochemical impedance study of polyaniline eleetrocoated porous carbon foam 显示文摘 | Melda S Elif A P Aysenur G | 2008 | Progress in Organic Coatings2008，62，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员