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| 1 | Novel pharmacological therapy in type 2 diabetes mellitus with established cardiovascular disease: Current evidence显示文摘Cardiovascular diseases(CVDs) remain the leading cause of death in the world and in most developed countries. Patients with type 2 diabetes mellitus(T2DM)suffer from both microvascular and macrovascular diseases and therefore have higher rates of morbidity and mortality compared to those without T2DM. If current trends continue, the Center for Disease Control and Prevention estimates that 1 in 3 Americans will have T2DM by year 2050. As a consequence of the controversy surrounding rosiglitazone and the increasing prevalence of diabetes and CVDs, in 2008 the Food and Drug Administration(FDA) established new expectations for the evaluation of new antidiabetic agents, advising for pre and,in some cases, post-marketing data on major cardiovascular events. As a direct consequence, there has been a paradigm shift in new antidiabetic agents that has given birth to the recently published American Diabetes Association/European Association for the Study of Diabetes consensus statement recommending sodium-glucose cotransporter-2 inhibitors(SGLT2i) and glucagon like peptide-1 receptor agonists(GLP-1RA) in patients with T2DM and established CVD. As a result of over a decade of randomized placebo controlled cardiovascular outcome trials, the aforementioned drugs have received FDA approval for risk reduction of cardiovascular(CV) events in patients with T2DM and established CV disease.SGLT2i have been shown to have a stronger benefit in patients with congestiveheart failure and diabetic kidney disease when compared to their GLP-1RA counterparts. These benefits are not withstanding additional considerations such as cost and the multiple FDA Black Box warnings. This topic is currently an emerging research area and this mini-review paper examines the role of these two novel classes of drugs in patients with T2DM with both confirmed, and at risk for, CVD. | Leonardo Pozo Fatimah Bello Andres Suarez Francisco E Ochoa-Martinez Yamely Mendez Chelsea H Chang Salim Surani | 2019 | World Journal of Diabetes2019，10，5： | 2 |
| 2 | Vereckei criteria as a diagnostic tool amongst emergency medicine residents to distinguish between ventricular tachycardia and supra-ventricular tachycardia with aberrancy显示文摘 | Rupen P. Baxi Kimberly W. Hart András Vereckei John Miller Sora Chung Wendy Chang Brent Gottesman Meagan Hunt Ginger Culyer Thomas Trimarco Christopher Willoughby Guillermo Suarez Christopher J. Lindsell Sean P. Collins | 2012 | Journal of Cardiology2012，，3： | 1 |
| 3 | History andpolicy of biodiesel in Brazil显示文摘 | GABRIELLA P A SANTOS ANDRL SUAREZ PAULO A | 2007 | Energy Policy2007，35，： | 1 |
| 4 | Aplasia cutis congenita : Surgical treatment and results in 36 cases 显示文摘 | Suarez O Lopez - Gutierrez JC Andres A | 2007 | Cir Pediatr2007，20，3： | 1 |
| 5 | Utility of bone SPEcT-CT in percutaneous vertebroplasty显示文摘 | Suarez MS Andres RP de Pablo PP | 2009 | Rev Esp Med Nu- cl2009，28，6： | 1 |
| 6 | Utility of bone SPECT-CT in percutaneous vertebroplasty显示文摘 | Suarez MS Andres RP de Pablo PP | 2009 | Rev Esp Med Nuc12009，28，6： | 1 |
| 7 | African swine fever virus protein p17 is essential for the progression of viral membrane precursors toward icosahedral intermediates 显示文摘 | Suarez C Gutierrez-Berzal J Andres G | 2010 | Virology2010，84，： | 1 |
| 8 | Aplasia cutis congenita: surgical treatment and results in 36 cases 显示文摘 | Suarez O Lo' pez-Gutie' rrez JC Andre' s A | 2007 | Cir Pediatr2007，20，： | 1 |
| 9 | Entrenchment and Severance Pay in Optimal Governance Structures 显示文摘 | Almazan Andres Javier Suarez | 2003 | Journal of Finance2003，，58： | 1 |
| 10 | 2D organic molecular metallic soft material derived from BEDO-TTF with electrochromic and rectifying properties显示文摘In this article we demonstrate that a migration of iodine species and chemical transformation in a moist environment induced by a voltage-biased Pt electrode is able to alter the color and degree of charge transfer in a layer of the 2D organic molecular metal(BEDO-TTF)_(2.4)I_(3)[BEDO=bis(ethylenedioxy)tetrathiafulvalene]self-assembled at the surface of a polycarbonate film.These effects produce a reversible electrochromic behavior of the layer with low operating voltages and fast operation times.Adjuvant with electrochromism,this flexible material exhibits rectifying behavior whose I-V curves are dependent on the voltage sweep directions.These results open new possibilities for the design and fabrication of organic flexible materials for soft electrochromic and rectifying components.The easy working principle ensures reliability,low power consumption,and versatility through its implementation into simple devices.Such working principle has been confirmed by temperature dependent resistance measurements,X-Ray,EDX-SEM,and conducting-AFM studies. | Daniel Suarez Eden Steven Elena Laukhina Andres Gomez Anna Crespi Narcis Mestres Concepcio Rovira Eun Sang Choi Jaume Veciana | 2018 | npj Flexible Electronics2018，2，1： | 0 |
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