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| 1 | Diagnosis and surgical management of breast cancer metastatic to the spine显示文摘Breast cancer is the most common malignancy and the second leading cause of death in Western women. Breast cancer most commonly metastasizes to the bone and has a particular affinity with the spine, accounting for 2/3 of osseous metastases discovered. With significant improvements in cancer therapies, the number of patients at risk for symptomatic spinal metastases is likely to increase. Patients may suffer from intractable pain and neurological dysfunction, negatively influencing their quality of life. Timely diagnosis of patients is crucial and has been aided by several breakthrough advances in imaging techniques which aid in detection, staging, and follow-up of bone metastases. Breast metastases are usually responsive to hormonal therapy and pharmacologic interventions, but skeletal metastases often require surgical intervention. The treatments are palliative but goals include the preserving or restoring neurologic function, ensuring spinal stability, and relieving pain. Advances in surgical techniques and instrumentation have allowed more effective decompres-sion and stabilization of the spine, and with the support of recent evidence the trend has shifted towards using more advanced surgical options in appropriately selected patients. In this review, the clinical presentation, diagnosis, patient selection, and surgical management of breast cancer metastatic to the spine are discussed. | Derek G Ju Alp Yurter Ziya L Gokaslan Daniel M Sciubba | 2014 | World Journal of Clinical Oncology2014，5，3： | 4 |
| 2 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 3 | Coronary artery stents and non-cardiac surgery 显示文摘 | Howard Alpe GM de Bono J Hudsmith L | 2007 | Br J Anaesth2007，98，5： | 1 |
| 4 | The effects of dietary oregano essential oil on live performance,carcass yield,serum immunoglobulin G level,and oocyst count in broilers显示文摘 | M Alp M Midilli N Kocaba(g)l | 2012 | J Appl Poult Res2012，21，： | 1 |
| 5 | Phonon density of states of iron up to 153 Gigapascals显示文摘 | Mao H.K Xu J Struzhkin V.V Shu J.F Hemley R.J Sturhahn W Wu M.Y Alp E.E Vocadlo L Alfe D Price G.D Gillan M.J Schwoerer-B(o)hning M H(a)usermann D Eng P Shen G Giefers H Lubbers R Wortmann G | | 0，，： | 1 |
| 6 | Pivotal role for endothelialtetrahydrobiopterin in pulmonary hypertension显示文摘 | Khoo JP Zhao L Alp NJ | 2005 | Circulation2005，111，16： | 1 |
| 7 | Molecular miscibility and chain dynamics in POSS/polystyrence blends:Control of POSS preferential dispersion states显示文摘 | Rahul Misra Alp H Alidedeoglu Willian L | | 0，，13： | 1 |
| 8 | Molecular miscibility and chain dynamics in POSS/polysty rene blends:Control of POSS preferential dispersion states 显示文摘 | Rahul Misra Alp H Alidedeoglu William L Jarrett | 2009 | Polymer2009，50，： | 1 |
| 9 | The effect of melatonin on procarbazine induced testicular toxicity on rats显示文摘 | Bilal F&inodot rat Alp Vural Kesik Ercan Malko? Nuri Yi&gbreve it Mehmet Sald&inodot r O&gbreve uzhan Babacan Emin ? zgü r Akgü l Yavuz Poyrazoglu Nadir Korkmazer Mustafa Gulgun Onur Erdem | 2014 | Systems Biology in Reproductive Medicine2014，，6： | 1 |
| 10 | Utilization of flotation wastes of copper slag as raw material in cement production显示文摘 | Alp L Deveci H Sungun H | 2008 | Journal of Hazardous Materials2008，159，2： | 1 |
| 11 | Adsorption of As ( V ) from water using Mg- Fe-based hydrotalcite (FeHT) 显示文摘 | TUrk T Alp l Deveci H | 2009 | J Hazard Mater2009，171，123： | 1 |
| 12 | Endometrial mRNA expression of matrix metalloproteinases,their tissue inhibitors and cell adhesion molecules in unexplained infertility and implantation failure patients显示文摘 | Konae E Alp E Onen H L | 2009 | Reprod Biomed Online2009，19，3： | 1 |
| 13 | Cognitive deficits in clinical and familial high risk groups for psychosis are common as in first episode schizophrenia显示文摘 | Alp ü?ok Ne?e Direk Ahmet Koyuncu Yasemin Keskin-Ergen ?a?r? Yüksel Jülide Güler Gül?ah Karaday? El?in Akturan Müge Devrim-ü?ok | 2013 | Schizophrenia Research (-)2013，，1： | 1 |
| 14 | Short-sequence DNA repeats in prokaryotic genomes显示文摘 | BELKUM A V SCHERER S ALP HEN L V etal | 1998 | Microbiol Mol Biol1998，62，2： | 1 |
| 15 | Molecular miscibility and chain dynamics in POSS/polystyrence blends: Control of POSS preferential dispersion states显示文摘 | Rahul Misra Alp H Alidedeoglu Willian L | 2009 | Polymer2009，50，13： | 1 |
| 16 | Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension显示文摘 | Khoo JP Zhao L Alp NJ | 2005 | Circulation2005，111，16： | 1 |
| 17 | Pivotal role for endothelialtetrahydrobiopterin in pulmonary hypertension显示文摘 | Khoo JP Zhao L Alp NJ etal | 2005 | Circulation2005，111，16： | 1 |
| 18 | Colour Doppler imaging of the orbital vasculature in Graves'disease with computed tomographic correlation显示文摘 | Alp MN Ozgen A Can L | 2000 | Br J Ophthalmol2000，84，9： | 1 |
| 19 | Molecular miscibility and chain dynamics in POSS/polystyrene blends: Control of POSS preferential dispersion states显示文摘 | Misra Rahul Alidedeoglu Alp H Jarrett William L | 2009 | Polymer2009，50，13： | 1 |
| 20 | Impact of allopurinol on risk of myocardial infarction显示文摘 | Grimaldi-Bensouda L Alpérovitch A Aubrun E | 2015 | Ann Rheum Dis2015，74，5： | 1 |
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