|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | AFP level and histologic differentiation predict the survival of patients with liver transplantation for hepatocellular carcinoma显示文摘BACKGROUND: In liver transplantation or resection for hepatocellular carcinoma (HCC), patient selection depends on morphological features. In patients with HCC, we performed a clinicopathological analysis of risk factors that affected survival after liver transplantation. METHODS: In 389 liver transplantations performed from 2004 to 2010, 102 were for HCC patients. Data were collected retrospectively from the Organ Transplantation Center Database. Variables were as follows: age, gender, preoperative alpha-fetoprotein (AFP) levels, Child-Pugh and MELD scores, prognostic staging criteria (Milan and UCSF), etiology, number of tumors, the largest tumor size, total tumor size, multifocality, intrahepatic portal vein tumor thrombosis, bilobarity, and histological differentiation. RESULTS: One hundred and two patients were evaluated. The 5-year overall survival rate was 56.5%. According to the UCSF criteria, 63% of the patients were within and 37% were beyond UCSF (P=0.03). Ten patients were excluded (one with fibrolamellary HCC and 9 because of early postoperative death without HCC recurrence), and 92 patients were assessed. The mean age of the patients was 56.5±6.9 years. Sixty-two patients underwent living donor liver transplantations. The mean follow-up time was 29.4±22.6 months. Fifteen patients (16.3%) died in the follow-up period due to HCC recurrence. Univariate analysis showed that AFP level, intrahepatic portal vein tumor thrombosis, histologic differentiation and UCSF criteria were significant factors related to survival and tumor recurrence. The 5-year estimated overall survival rate was 62.2% in allpatients. According to the UCSF criteria, and the 5-year overall survival rate was 66.7% within and 52.7% beyond the criteria (P=0.04). Multivariate analysis showed that AFP level and poor differentiation were independent factors. CONCLUSIONS: For proper patient selection in liver trans- plantation for HCC, prognostic criteria related to tumor biology (especially AFP level and histological differentiation) should be considered. Poor differentiation and higher AFP levels are indicators of poor prognosis after liver transplantation. | Onur Yaprak Murat Akyildiz Murat Dayangac Baha Tolga Demirbas Necdet Guler Gulen Bulbul Dogusoy Yildiray Yuzer Yaman Tokat | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 15 |
| 2 | 帕罗西汀与达帕西汀的对比,治疗早泄的新的选择性5-羟色胺再摄取抑制剂显示文摘达帕西汀氢氯化物是一种选择性5-羟色胺再摄取抑制剂,也是第一种被批准可以按需服用治疗早泄的药物。本文目的为研究按需服用达帕西汀(30mg和H60mg)和每日服用帕罗西汀(20mg)对早泄的疗效。研究募集了150名患者进行了长达1个月的研究。患者被分成3组,每组50人。第一组按需服用达帕西汀30mg。第二组按需服用达帕西汀60mg。第三组每日服用帕罗西汀20mg。治疗结束后,我们的结果检测值相对于基准阴道内射精潜伏期(IELT)延长了。与基准IELT相比,帕罗西汀组、30mg达帕西汀组和60mg达帕西汀组的治疗后IELT分别延长了117%(P〈0.01),117%(P〈0.01)和170%(P〈0.01)。30mg达帕西汀组和帕罗西汀组的IELT增幅相同(P〉0.05),而60mg达帕西汀组的IELT增幅明显高于30mg达帕西汀组(P〈0.05和帕罗西汀组P〈0.01)。性交前1~3小时服用达帕西汀60mg是针对早泄的非常有效的治疗方法。然而,与当前普遍使用的帕罗西汀相比,达帕西汀30mg疗效并不显著。 | Abdulmuttalip Simsek Sinan Levent Kirecci Onur Kucuktopcu Faruk Ozgor Mehmet Fatih Akbulut Omer Sarilar Unsal Ozkuvanci Zafer Gokhan Gurbuz | 2014 | Asian Journal of Andrology2014，16，5： | 10 |
| 3 | 纤维复合板的冲击响应综述显示文摘对由E-玻纤作为增强材料、环氧树脂作为基材的织物复合纤维板的冲击响应进行综述。在4~45J入射冲击能下进行了一系列试验,从而能逐步考察从初始破坏到最终破坏的全过程。试验结果显示:单个试件的破坏过程可以通过相应的荷载—挠度曲线、能量断面图以及破坏试件的图像进行重构。除了荷载—挠度曲线外,还对其他冲击参数的变化,如吸收能、冲击速度与变形或时间的关系等也进行了描述。同时建立了这些冲击参数与破坏过程的相关关系。 | Cesim Atas Onur Sayman | 2008 | 钢结构2008，23，7： | 9 |
| 4 | Numerical and analytical simulation of the structural behaviour of fully grouted cable bolts under impulsive loading显示文摘Designing reliable yielding support system to mitigate the effect of the kinetic energy in burst-prone conditions in mining and tunneling excavations is one of the challenges for geotechnical engineers. A combination of the support elements can be used to increase rock strength and minimise the displacement of unstable rock mass. It is important to understand how the support system works to ensure the stability of underground excavations. Cable bolts have been commonly used as an effective underground support system and an element of reinforcement to improve rock stability. Cable bolts are usually considered to be subjected to static loads under relatively low stress environments, however, in burst-prone conditions, they might be subjected to dynamic loads. Cable bolts as well as other support elements are used in burst-prone conditions to absorb the kinetic energy of the removed rock to avoid sudden and violent failures. This paper develops numerical and a novel analytical simulation technique for cable bolts to assess their structural behaviour under static and dynamic loading conditions. The numerical and analytical models are then validated against experimental observations reported in the literature, which demonstrates the reliability of the proposed models. | Faham Tahmasebinia Chengguo Zhang Ismet Canbulat Onur Vardar Serkan Saydam | 2018 | International Journal of Mining Science and Technology2018，28，5： | 9 |
| 5 | Glasgow coma scale and APACHE-II scores affect the liver transplantation outcomes in patients with acute liver failure显示文摘BACKGROUND:The timing and selection of patients for liver transplantation in acute liver failure are great challenges.This study aimed to investigate the effect of Glasgow coma scale(GCS)and APACHE-II scores on liver transplantation outcomes in patients with acute liver failure.METHOD:A total of 25 patients with acute liver failure were retrospectively analyzed according to age,etiology,time to transplantation,coma scores,complications and mortality.RESULTS:Eighteen patients received transplants from live donors and 7 had cadaveric whole liver transplants.The mean duration of follow-up after liver transplantation was 39.86±40.23 months.Seven patients died within the perioperative period and the 1-,3-,5-year survival rates of the patients were72%,72%and 60%,respectively.The parameters evaluated for the perioperative deaths versus alive were as follows:the mean age of the patients was 33.71 vs 28 years,MELD score was 40 vs32.66,GCS was 5.57 vs 10.16,APACHE-II score was 23 vs 18.11,serum sodium level was 138.57 vs 138.44 mmol/L,mean waiting time before the operation was 12 vs 5.16 days.Low GCS,high APACHE-II score and longer waiting time before the operation(P<0.01)were found as statistically significant factors for perioperative mortality.CONCLUSION:Lower GCS and higher APACHE-II scores are related to poor outcomes in patients with acute liver failure after liver transplantation. | Necdet Guler Omer Unalp Ayse Guler Onur Yaprak Murat Dayangac Murat Sozbilen Murat Akyildiz Yaman Tokat | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 9 |
| 6 | Current and future surgery strategies for spinal cord injuries显示文摘Spinal cord trauma is a prominent cause of mortality and morbidity. In developed countries a spinal cord injury(SCI) occurs every 16 min. SCI occurs due to tissue destruction, primarily by mechanical and secondarily ischemic. Primary damage occurs at the time of the injury. It cannot be improved. Following the primary injury, secondary harm mechanisms gradually result in neuronal death. One of the prominent causesof secondary harm is energy deficit, emerging from ischemia, whose main cause in the early stage, is impaired perfusion. Due to the advanced techniques in spinal surgery, SCI is still challenging for surgeons. Spinal cord doesn't have a self-repair property. The main damage occurs at the time of the injury primarily by mechanical factors that cannot be improved. Secondarily mechanisms take part in the following sections. Spinal compression and neurological deficit are two major factors used to decide on surgery. According to advanced imaging techniques the classifications systems for spinal injury has been changed in time. Aim of the surgery is to decompress the spinal channel and to restore the spinal alinement and mobilize the patient as soon as possible. Use of neuroprotective agents as well as methods to achieve cell regeneration in addition to surgery would contribute to the solution. | Sedat Dalbayrak Onur Yaman Tevfik Y?lmaz | 2015 | World Journal of Orthopedics2015，6，1： | 7 |
| 7 | Orbital decompression surgery for the treatment of Graves' ophthalmopathy:comparison of different techniques and long-term results显示文摘AIM: To evaluate the long-term results of different orbital decompression techniques performed in patients with Graves' ophthalmopathy(GO).METHODS: Totally 170 cases with GO underwent orbital decompression between 1994 and 2014. Patients were divided into 4 groups as medial-inferior, mediallateral(balanced), medial-lateral-inferior, and lateral only according to the applied surgical technique. Surgical indications, regression degrees on Hertel exophthalmometer, new-onset diplopia in the primary gaze and new-onset gaze-evoked diplopia after surgery and visual acuity in cases with dysthyroid optic neuropathy(DON) were compared between different surgical techniques.RESULTS: The study included 248 eyes of 149 patients. The mean age for surgery was 42.3±13.2 y. DON was the surgical indication in 36.6% of cases, and three-wall decompression was the most preferred technique in these cases. All types of surgery significantly decrease the Hertel values(P<0.005). Balanced medial-lateral, and only lateral wall decompression caused the lowest rate of postoperative new-onset diplopia in primary gaze. The improvement of visual acuity in patients with DON did not significantly differ between the groups(P=0.181). CONCLUSION: The study show that orbital decompression surgery has safe and effective long term results for functional and cosmetic rehabilitation of GO. It significantly reduces Hertel measurements in disfiguring proptosis and improves visual functions especially in DON cases. | Mehmet Ozgur Cubuk Onur Konuk Mehmet Unal | 2018 | International Journal of Ophthalmology(English edition)2018，11，8： | 7 |
| 8 | Arterial complication of irreversible electroporation procedure for locally advanced pancreatic cancer显示文摘Irreversible electroporation(IRE) is a non-thermal ablation technique used especially in locally advanced pancreatic carcinomas that are considered surgically unresectable.We present the first case of acute superior mesenteric artery(SMA) occlusion secondary to pancreatic IRE procedure that has not been reported before in the literature.A 66-year-old man underwent neoadjuvant chemoradiotherapy for locally advanced pancreatic ductal adenocarcinoma.IRE procedure was applied to the patient during laparotomy under general anesthesia.After finishing the procedure,an acute intestinal ischemia was detected.A conventional vascular angiography was performed and a metallic stent was successfully placed to the SMA and blood flow was maintained.It is important to be careful in such cases of tumor involvement of SMA when evaluating for IRE procedure of pancreatic tumor. | Yahya Ekici Tugan Tezcaner Hüseyin Onur Aydin Fatih Boyvat G?khan Moray | 2016 | World Journal of Gastrointestinal Oncology2016，8，10： | 5 |
| 9 | Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?显示文摘ObjectiveCoronary 动脉绕过 grafting (CABG ) 逐渐地在老人口正在增加。我们试图在 80 的年龄和 older.MethodsBetween 2002年1月和2011年12月在病人与长期的幸存一起调查风险因素和 CABG 的结果,在 80 的年龄的 101 个连续病人的一个总数并且更旧在我们的医院里经历了 CABG 的人,在学习被包括。病人被跟随,长期的幸存是病人的 estimated.ResultsThe 平均数年龄是 82.98 ±2.27 年。(63.4%) 64 是男性,(36.6%) 37 是女性。紧急情况外科,持续时间心肺绕过,特别护理单位(ICU ) 停留, inotropic 支持,大动脉的汽球跳动申请,红血球输送的数量和新鲜冻结的血浆输送和通风时期是的 intra 在在医院里死了的病人显著地更高。持续时间心肺绕过(CPB ) 被发现是死亡的一个独立预言者(或:1.18, 95% CI 1.01 − 1.38, P = 0.034 ) 。在里面医院死亡是 16.8% 。Kaplan-Meier 分析在一年揭示了 91.3% 的幸存比率, 82.9% 在三年并且 69.0% 在五 years.ConclusionsPatients 在 80 岁时并且更旧 CABG 过程的候选人能正在牢记他们可以有一个更长的通风时期和特别护理单位停留。这个年龄组的病态和死亡在一个可接受的范围以内被考虑。最小化 CPB 的途径,或离开泵外科的选择,可以是一个预防方法降低死亡的发生。因此, CABG 可以与令人满意的幸存比率在这个年龄组被执行。 | Anil Ozen Ertekin Utku Unal Murat Songur Sinan Sabit Kocabeyoglu Onur Hanedan Metin Yilmaz Basak Soran Turkcan Ferit Cicekcioglu Sadi Kaplan Cemal Levent Birincioglu | 2015 | Journal of Geriatric Cardiology2015，12，2： | 5 |
| 10 | Challenges and Prospects of Nanopillar-Based Solar Cells显示文摘Materials and device architecture innovations are essential for further enhancing the performance of solar cells while potentially enabling their large-scale integration as a viable source of alternative energy.In this regard,tremendous research has been devoted in recent years with continuous progress in the field.In this article,we review the recent advancements in nanopillar-based photovoltaics while discussing the future challenges and prospects.Nanopillar arrays provide unique advantages over thin films in the areas of optical properties and carrier collection,arising from their three-dimensional geometry.The choice of the material system,however,is essential in order to gain the advantage of the large surface/interface area associated with nanopillars with the constraints different from those of the thin film devices. | Zhiyong Fan Daniel J.Ruebusch Asghar A.Rathore Rehan Kapadia Onur Ergen Paul W.Leu Ali Javey | 2009 | Nano Research2009，2，11： | 5 |
| 11 | Hepatic vein in living donor liver transplantation显示文摘Right lobe living donor liver transplantation(LDLT)is a major development in adult LDLT that has significantly increased the donor pool by providing larger graft size and by decreasing risk of small-for-size graft syndrome.However,right lobe anatomy is complex,not only from the inflow but also from the outflow perspective.Outflow reconstruction is one of the key requirements of a successful LDLT and venous drainage of the liver graft is just as important as hepatic inflow for the integrity of graft function.Outflow complications may cause acute graft failure which is not always easy to diagnose.The right lobe graft consists of two sections and three hepatic venous routes for drainage that require reconstruction.In order to obtain a congestion free graft,several types of vascular conduits and postoperative interventions are needed to assure an adequate venous allograft drainage.This review described the anatomy,functional basis and the evolution of outflow reconstruction in right lobe LDLT. | Deniz Balci Elvan Onur Kirimker | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，4： | 4 |
| 12 | Role of pre-transplant 18F-FDG PET/CT in predicting hepatocellular carcinoma recurrence after liver transplantation显示文摘The last two decades have seen a paradigm shift in the selection of patients with hepatocellular carcinoma(HCC)for liver transplantation.Microvascular invasion and differentiation have been the most significant factors affecting post-transplant recurrence;however,because of inherent disadvantages of pre-transplant biopsy,histological criteria never gained popularity.Recently,the selection criteria evolved from morphological to biological criteria,such as biomarkers and response to loco-regional therapy.With the introduction of multimodality imaging,combination of computed tomography with nuclear medicine imaging,particularly,18F-fluorodeoxyglucose positron emission tomography fulfilled an unmet need and rapidly became a critical component of HCC management.This review article will focus on the use of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in the pre-transplant evaluation of HCC patients with special discussion on its ability to predict HCC recurrence after liver transplantation. | Onur Yaprak Sencan Acar Gokhan Ertugrul Murat Dayangac | 2018 | World Journal of Gastrointestinal Oncology2018，10，10： | 4 |
| 13 | 一名无精症和开咬合畸形男性体内的额外标记染色体15显示文摘额外标记染色体15(sSMC[15])是最常见的标记染色体,通常认为如果不包含Prader-Willi/Angelman综合症关键区(Prader-Willi/Angelman syndrome critical region,PWACR),这一标记染色体就无关紧要。较大标记的关键区域的临床意义在几乎所有与标记染色体15相关的报告中都被提及,较小的标记仅与轻微畸形、无精症、习惯性流产相关。然而,这些不包含PWACR的小额外标记染色体15也可能决定某一基因表现型。我们在一个遗传学门诊对一名无精症病人进行畸形检查,根据标准的细胞遗传学方法进行外周血淋巴染色体分析,还对Y染色体微缺失进行了核仁组织区(NOR)连接、C-连接、荧光原位杂交(Fluorescence in situ hybridization,FISH)以及分子学研究。临床评估确定为畸形特征伴有无精症及重度“安氏Ⅱ类1分类开咬合畸形”。分子细胞遗传结果显示有小额外标记染色体15存在,此外,Y染色体微缺失分析显示无精症不是Y染色体微缺失的结果。额外标记染色体15和下颌不规则的症状同时出现在这一病例中,这可能只是巧合,但也可能标明了一个不仅只是无精症的特定表现型,其特征包括不育、颧骨发育不全、下颌不规则、瘢痕瘤形成以及轻微畸形特征。 | Altug Koc Odul Onur Mehmet Ali Ergun E. Ferda Pergin | 2009 | Asian Journal of Andrology2009，11，5： | 4 |
| 14 | All-optical synthesis of an arbitrary linear transformation using diffractive surfaces显示文摘Spatially-engineered diffractive surfaces have emerged as a powerful framework to control light-matter interactions for statistical inference and the design of task-specific optical components.Here,we report the design of diffractive surfaces to all-optically perform arbitrary complex-valued linear transformations between an input(Ni)and output(No),where Ni and No represent the number of pixels at the input and output fields-of-view(FOVs),respectively.First,we consider a single diffractive surface and use a matrix pseudoinverse-based method to determine the complex-valued transmission coefficients of the diffractive features/neurons to all-optically perform a desired/target linear transformation.In addition to this data-free design approach,we also consider a deep learning-based design method to optimize the transmission coefficients of diffractive surfaces by using examples of input/output fields corresponding to the target transformation.We compared the all-optical transformation errors and diffraction efficiencies achieved using data-free designs as well as data-driven(deep learning-based)diffractive designs to all-optically perform(i)arbitrarily-chosen complex-valued transformations including unitary,nonunitary,and noninvertible transforms,(ii)2D discrete Fourier transformation,(iii)arbitrary 2D permutation operations,and(iv)high-pass filtered coherent imaging.Our analyses reveal that if the total number(N)of spatially-engineered diffractive features/neurons is≥Ni×No,both design methods succeed in all-optical implementation of the target transformation,achieving negligible error.However,compared to data-free designs,deep learning-based diffractive designs are found to achieve significantly larger diffraction efficiencies for a given N and their all-optical transformations are more accurate for N | Onur Kulce Deniz Mengu Yair Rivenson Aydogan Ozcan | 2021 | Light(Science & Applications)2021，10，10： | 3 |
| 15 | Synthesis,Contact Printing,and Device Characterization of Ni-Catalyzed,Crystalline InAs Nanowires显示文摘InAs nanowires have been actively explored as the channel material for high performance transistors owing to their high electron mobility and ease of ohmic metal contact formation.The catalytic growth of nonepitaxial InAs nanowires,however,has often relied on the use of Au colloids which is non-CMOS compatible.Here,we demonstrate the successful synthesis of crystalline InAs nanowires with high yield and tunable diameters by using Ni nanoparticles as the catalyst material on amorphous SiO_(2) substrates.The nanowires show superb electrical properties with field-effect electron mobility~2700 cm^(2)/Vs and ION/IOFF>10^(3).The uniformity and purity of the grown InAs nanowires are further demonstrated by large-scale assembly of parallel arrays of nanowires on substrates via the contact printing process that enables high performance,“printable”transistors,capable of delivering 510 mA ON currents(~400 nanowires). | Alexandra C.Ford Johnny C.Ho Zhiyong Fan Onur Ergen Virginia Altoe Shaul Aloni Haleh Razavi Ali Javey | 2008 | Nano Research2008，1，1： | 3 |
| 16 | A semi-quantitative coal burst risk classification system显示文摘Safety is the highest priority in the mining industry as underground mining in particular poses high safety risks to its workers. In underground coal mines, coal bursts are one of the most catastrophic hazards, which involves sudden and violent dynamic coal mass failure with rapid ejection of the broken material into the mine workings. Despite decades of research, the contributing mechanisms of coal bursts are still not completely understood. Hence, it remains challenging to forecast coal bursts and quantify their likelihood of occurrence. However, a range of geological and geotechnical factors are associated with coal bursts and can increase the coal burst proneness. This paper introduces a semi-quantitative coal burst risk classification system, namely, BurstRisk. Based on back-analysis of case histories from Australia, China and the United States, BurstRisk classifies the coal burst risk into three categories:low, medium and high risk. In addition, it allows mining engineers to modify the weighting of the selected factors based on specific conditions. The risk classification charts introduced are for both longwall retreat and development sections of long-wall mining operations. This paper also provides a set of risk management strategies and control measures for effective coal burst mitigation. | Onur Vardar Chengguo Zhang Ismet Canbulat Bruce Hebblewhite | 2018 | International Journal of Mining Science and Technology2018，28，5： | 3 |
| 17 | Polarization multiplexed diffractive computing:all-optical implementation of a group of linear transformations through a polarization-encoded diffractive network显示文摘Research on optical computing has recently attracted significant attention due to the transformative advances in machine learning.Among different approaches,diffractive optical networks composed of spatially-engineered transmissive surfaces have been demonstrated for all-optical statistical inference and performing arbitrary linear transformations using passive,free-space optical layers.Here,we introduce a polarization-multiplexed diffractive processor to all-optically perform multiple,arbitrarily-selected linear transformations through a single diffractive network trained using deep learning.In this framework,an array of pre-selected linear polarizers is positioned between trainable transmissive diffractive materials that are isotropic,and different target linear transformations(complex-valued)are uniquely assigned to different combinations of input/output polarization states.The transmission layers of this polarization-multiplexed diffractive network are trained and optimized via deep learning and error-backpropagation by using thousands of examples of the input/output fields corresponding to each one of the complex-valued linear transformations assigned to diffferent input/output polarization combinations.Our results and analysis reveal that a single diffractive network can successfully approximate and all-optically implement a group of arbitrarily-selected target transformations with a negligible error when the number of trainable diffractive features/neurons(N)approaches N_(p)N_(i)N_(o),where Ni and N_(o) represent the number of pixels at the input and output fields-of-view,respectively,and N_(p) refers to the number of unique linear transformations assigned to different input/output polarization combinations.This polarization-multiplexed all-optical diffractive processor can find various applications in optical computing and polarization-based machine vision tasks. | Jingxi Li Yi-Chun Hung Onur Kulce Deniz Mengu Aydogan Ozcan | 2022 | Light(Science & Applications)2022，11，7： | 3 |
| 18 | All-optical information-processing capacity of diffractive surfaces显示文摘The precise engineering of materials and surfaces has been at the heart of some of the recent advances in optics and photonics.These advances related to the engineering of materials with new functionalities have also opened up exciting avenues for designing trainable surfaces that can perform computation and machine-learning tasks through light-matter interactions and diffraction.Here,we analyze the information-processing capacity of coherent optical networks formed by diffractive surfaces that are trained to perform an all-optical computational task between a given input and output field-of-view.We show that the dimensionality of the all-optical solution space covering the complex-valued transformations between the input and output fields-of-view is linearly proportional to the number of diffractive surfaces within the optical network,up to a limit that is dictated by the extent of the input and output fields-of-view.Deeper diffractive networks that are composed of larger numbers of trainable surfaces can cover a higher-dimensional subspace of the complex-valued linear transformations between a larger input field-of-view and a larger output field-of-view and exhibit depth advantages in terms of their statistical inference,learning,and generalization capabilities for different image classification tasks when compared with a single trainable diffractive surface.These analyses and conclusions are broadly applicable to various forms of diffractive surfaces,including,e.g.,plasmomc and/or dielectric-based metasurfaces and flat optics,which can be used to form all-optical processors. | Onur Kulce Deniz Mengu Yair Rivenson Aydogan Ozcan | 2021 | Light(Science & Applications)2021，10，2： | 3 |
| 19 | Major complications of adult right lobe living liver donors显示文摘BACKGROUND:The right lobe of the liver is generally preferred for living donor liver transplantation in adult patients with end-stage liver disease.It is important to know the preoperative factors relating to the major postoperative complications.We therefore evaluated the possible risk factors for predicting postoperative complications in right lobe liver donors.METHODS:Data from 378 donors who had undergone | Necdet Guler Onur Yaprak Yusuf Gunay Murat Dayangac Murat Akyildiz Fisun Yuzer Yildiray Yuzer Yaman Tokat | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，2： | 3 |
| 20 | Colorectal stenting for palliation and as a bridge to surgery:A 5-year follow-up study显示文摘AIM: To evaluate the long-term effectiveness of colonic stents in colorectal tumors causing large bowel obstruction.METHODS: We retrospectively analyzed data from 49 patients with colorectal cancer who had undergone colorectal stent placement between January 2008 and January 2013. Patients' symptoms,characteristics and clinicopathological data were obtained by reviewing medical records. The obstruction was diagnosed clinically and radiologically. Histopathological diagnosis was achieved endoscopically. Technical success rate(TSR)was defined as the ratio of patients with correctly placed SEMS upon stent deployment across the entire stricture length to total number of patients. Clinical success rate(CSR) was defined as the ratio of patients with technical success and successful maintenance of stent function before elective surgery(regardless of number of SEMS deployed) to total number of patients. The surgical success rate(SSR) of colorectal stent as a bridge to surgery was defined as the ratio of patients with successful surgical procedures. Unsuccessful surgical outcomes were defined as being due to insufficient colonic decompression. The technical,clinical,surgical success rates and complications after stenting were assessed.RESULTS: The median age of patients was 64(36 to 89). 44.9% of patients were male and 55.1% were female. Eighteen patients had the obstruction located in the rectum,15 patients in the rectosigmoid region,10 patients in the sigmoid region,and 6 patients had a tumor causing obstruction in the proximal colon. Each patient was categorized pathologically as stage 2(32.7%,16 patients) or stage 3(42.9%,21 patients) and 12 patients(24.4%) had metastatic disease. None of the patients received chemotherapy before stenting. Stenting was undertaken in 37 patients as a bridge to surgery,and in 12 patients stents were used for palliation. Median time to surgery after stenting was 30 ± 91.9 d. All surgery was completed in one single operation and thus no colostomy with stoma was needed. The median overall survival rate of patients with stage 2-3 colorectal cancer was 53.1 mo and stage 4 was 37.1 mo(P = 0.04). Metastatic colorectal patients who were treated palliatively with stents had backbone chemotherapy with oxaliplatin and/or irinotecan-based regimens plus antiangiogenic therapies,especially bevacizumab. Resolution of the obstruction and clinical improvement was achieved in all patients. The technical,clinical and surgical success rates were 95.9%,100% and 94.6%,respectively.CONCLUSION: The efficacy and safety of colonic stents was demonstrated both as a bridge to surgery and for palliative decompression. In addition,results emphasize the importance of the skills of the endoscopist in colonic stenting. | Baris Bayraktar Ibrahim Ali Ozemir Umut Kefeli Gokhan Demiral Julide Sagiro?lu Onur Bayraktar Gupse Adali Alp Ozcelik Osman Baran Tortum | 2015 | World Journal of Gastroenterology2015，21，31： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员