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| 1 | Antimicrobial susceptibility testing before first-line treatment for Helicobacter pylori infection in patients with dual or triple antibiotic resistance显示文摘AIM To evaluate the efficacy of antimicrobial susceptibilityguided therapy before first-line treatment for infection in patients with dual or triple antibiotic resistance.METHODS A total of 1034 patients infected by Helicobacter pylori(H. pylori) during 2013-2014 were tested for antimicrobial susceptibility. 157 of 1034(15%) patients showed resistance to two(127/1034; 12%) and to three(30/1034; 3%) antibiotics. Sixty-eight patients with dual H. pylori-resistance(clarithromycin, metronidazole or levofloxacin) were treated for 10 d with triple therapies: OAL(omeprazole 20 mg b.i.d., amoxicillin 1 g b.i.d., and levofloxacin 500 mg b.i.d.) 43cases, OAM(omeprazole 20 mg b.i.d., amoxicillin 1 g b.i.d., and metronidazole 500 mg b.i.d.) 12 cases and OAC(omeprazole 20 mg b.id., amoxicillin 1 g b.i.d., and clarithromycin 500 mg b.i.d.) 13 cases based on the antimicrobial susceptibility testing. Twelve patients showed triple H. pylori-resistance(clarithromycin, metronidazole and levofloxacin) and received for 10 d triple therapy with OAR(omeprazole 20 mg b.id., amoxicillin 1 g b.i.d., and rifabutin 150 mg b.i.d.). Eradication was confirmed by 13C-urea breath test. Adverse effects and compliance were assessed by a questionnaire. RESULTS Intention-to-treat eradication rates were: OAL(97.6%), OAM(91.6%), OAC(92.3%) and OAR(58.3%). Cure rate was significantly higher in na?ve patients treated with OAR-10 compared to patients who had two or three previous treatment failures(83% vs 33%). Adverse events rates for OAL, OAM, OAC and OAR were 22%, 25%, 23% and 17%, respectively, all of them mild-moderate. CONCLUSION Antimicrobial susceptibility-guided triple therapies during 10 d for first-line treatment leads to an eradication rate superior to 90% in patients with dual antibiotic H. pylori resistance. | Angel Cosme Milagrosa Montes Begona Ibarra Esther Tamayo Horacio Alonso Usua Mendarte Jacobo Lizasoan Marta Herreros-Villanueva Luis Bujanda | 2017 | World Journal of Gastroenterology2017，23，18： | 4 |
| 2 | Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding显示文摘 | Emilio Estévez Benito González-Conde José Luis Vázquez-Iglesias Maria de los Angeles Vázquez-Millán Sonia Pértega Pedro A. Alonso Joan Clofent Eva Santos José Luis Ulla Eloy Sánchez | 2006 | European Journal of Gastroenterology & Hepatology2006，，8： | 3 |
| 3 | Role of Nitrogen and Nutrients in Crop Nutrition显示文摘 | Vicente Torres-Olivar Oscar Gabriel Villegas-Torres Martha Lilia Dominguez-Patifio Hoctor Sotelo-Nava Antonio Rodrlguez-Martme Rosa Maria Melgoza-Aleman Luis Alonso Valdez-Aguilar Irfin Alia-Tejacal | 2014 | Journal of Agricultural Science and Technology(B)2014，4，1： | 3 |
| 4 | Immunogenic properties of rabbit haemorrhagic disease virus structural protein VP60 expressed by a recombinat baculovirus: an efficient vaccine显示文摘 | Soledad Marin Jose M Martin Alonso Luis I | 1995 | Virus Research1995，39，： | 1 |
| 5 | Clinical assessment of heart-type fatty acid binding protein in early diagnosis of acute coronary syndrome显示文摘 | Hector Alonso Valle Luis García-Castrillo Riesgo Miguel Sántalo Bel Francisco Epelde Gonzalo Miguel Sánchez Sanchez Luis Iglesias Oliva | 2008 | European Journal of Emergency Medicine2008，，3： | 1 |
| 6 | 查看详情显示文摘 | Martínez-Pérez M.J Cardona-Serra S Schlegel C Moro F. Alonso P.J. Prima-García H. Clemente-Juan J.M. Evangelisti M. Gaita-Arif A. Sesé J. van Slageren J. Coronado E. Luis F | | 0，，： | 1 |
| 7 | Enhancing the potential value of environmental services in urban wetlands:An agro-ecosystem approach显示文摘 | ALONSO A I LUIS Z ELSA L V | 2013 | CITIES2013，31，： | 1 |
| 8 | Analysis of saffron volatile fraction by TD–GC–MS and e-nose显示文摘 | Manuel Carmona Javier Martínez Amaya Zalacain Ma Luz Rodríguez-Méndez José Antonio Saja Gonzalo Luis Alonso | 2006 | European Food Research and Technology2006，，1： | 1 |
| 9 | 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture显示文摘 | Carlos Guijarro Luis Miguel Blanco-Colio Monica Ortego Covadonga Alonso Alberto Ortiz Juan Jose Plaza Cristina Diaz Gonzalo Hernandez Jesus Egido | 1998 | Circulation Research1998，，5： | 1 |
| 10 | Enhancement of Nasal Absorption of Insulin Using Chitosan Nanoparticles显示文摘 | Rocío Fernández-Urrusuno Pilar Calvo Carmen Remu?án-López Jose Luis Vila-Jato María José Alonso | 1999 | Pharmaceutical Research1999，，10： | 1 |
| 11 | Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana:Unique and overlapping functions of ARF7 and ARF19显示文摘 | OKUSHIMA Y OVERVOORDE P J ARIMA K ALONSO J M CHAN A CHANG C ECKER J R HUGHES B LUI A NGUYEN D ONODERA C QUACH H SMITH A YU G THEOLOGIS A | 2005 | Plant Cell2005，17，2： | 1 |
| 12 | Chitosan and Chitosan/Ethylene Oxide-Propylene Oxide Block Copolymer Nanoparticles as Novel Carriers for Proteins and Vaccines显示文摘 | Pilar Calvo Carmen Remu?an-López Jose Luis Vila-Jato María José Alonso | 1997 | Pharmaceutical Research1997，，10： | 1 |
| 13 | Prevalence and Factors Associated With Circadian Blood Pressure Patterns in Hypertensive Patients显示文摘 | Alejandro de la Sierra Josep Redon José R. Banegas Julián Segura Gianfranco Parati Manuel Gorostidi Juan J. de la Cruz Javier Sobrino José L. Llisterri Javier Alonso Ernest Vinyoles Vicente Pallarés Antonio Sarría Pedro Aranda Luis M. Ruilope | 2009 | Hypertension2009，，3： | 1 |
| 14 | Extractable soil heavy metals following the cessation of biosolids application to agricultural soil显示文摘 | Walter Ingrid Mart?nez Fernando Alonso Luis | 2002 | Environmental Pollution2002，117，： | 1 |
| 15 | Pre- and post-conization high-risk HPV testing predicts residual/recurrent disease in patients treated for CIN 2–3显示文摘 | Immaculada Alonso Aureli Torné Luis M. Puig-Tintoré Roser Esteve Lloren? Quinto Elias Campo Jaume Pahisa Jaume Ordi | 2006 | Gynecologic Oncology2006，，2： | 1 |
| 16 | Extractable soil heavy metals following the cessation of biosolids application to agricultural soil显示文摘 | Walter Ingrid Martinez Fernando Alonso Luis | 2002 | Environmental Pollution2002，117，： | 1 |
| 17 | Pre- and post-conization high-risk HPV testing predicts residual/recurrent disease in patients treated for CIN 2–3显示文摘 | Immaculada Alonso Aureli Torné Luis M. Puig-Tintoré Roser Esteve Lloren? Quinto Elias Campo Jaume Pahisa Jaume Ordi | 2006 | Gynecologic Oncology2006，，2： | 1 |
| 18 | Acute abdomen in systemic lupus erythematosus: the importance of early laparotomy显示文摘 | Francisco M Alonso A Luis J J | 1997 | AmJ Med1997，102，： | 1 |
| 19 | Analysis of Neutnd-point Voltage Balancing Problem in Three-level Neutral-point-clamped Inverters with SVPWM Modulation显示文摘 | Oscar Alonso Luis Marroyo Pablo Sanchis | 2002 | IECON-20022002，2，1： | 1 |
| 20 | Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding显示文摘 | Emilio Estévez Benito González-Conde José Luis Vázquez-Iglesias Maria de los Angeles Vázquez-Millán Sonia Pértega Pedro A. Alonso Joan Clofent Eva Santos José Luis Ulla Eloy Sánchez | 2006 | European Journal of Gastroenterology & Hepatology2006，，8： | 1 |
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