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| 1 | 影响颅内动脉瘤破裂风险的患者个体特征(英文)显示文摘BACKGROUND AND PURPOSE Knowledge about risk factors contributes to understanding the pathophysiological mechanisms that cause intracranial aneurysm rupture and helps to develop possible treatment strategies.We aimed to study lifestyle and personal characteristics as risk factors for the rupture of intracranial aneurysms.METHODS We performed a case-control study with 250 patients with an aneurysmal subarachnoid hemorrhage and 206 patients with an unruptured intracranial aneurysm.All patients with an aneurysmal subarachnoid hemorrhage and patients with a unruptured intracranial aneurysm were asked to fill in a structured questionnaire about their lifestyle and medical history.For patients with an unruptured intracranial aneurysm,we also collected data on the indication for imaging.With logistic regression analysis,we identified independent risk factors for aneurysmal rupture.RESULTS Reasons for imaging in patients with an unruptured intracranial aneurysm were atherosclerotic disease(23%),positive family history(18%),headache(8%),preventive screening(3%),and other(46%).Factors that increased risk for aneurysmal rupture were smoking(odds ratio,1.9;95% confidence interval,1.2-3.0) and migraine(2.4;1.1-5.1);hypercholesterolemia decreased this risk(0.4;0.2-1.0),whereas a history of hypertension did not independently influence the risk.CONCLUSIONS Smoking,migraine and,inversely,hypercholesterolemia are independent risk factors for aneurysmal rupture.Data from the questionnaire are insufficient to conclude whether hypercholesterolemia or its treatment with statins exerts a risk-reducing effect.The pathophysiological mechanisms through which smoking and migraine increase the risk of aneurysmal rupture should be investigated in further studies.Although a history of hypertension does not increase risk of rupture,a sudden rise in blood pressure might still trigger aneurysmal rupture. | Vlak MH Rinkel GJ Greebe P Algra A | 2013 | 中华神经外科疾病研究杂志2013，12，3： | 17 |
| 2 | 美国国家卒中协会短暂性脑缺血发作处理指南显示文摘目的:短暂性脑缺血发作(TIA)是常见和重要的卒中先兆。其处理方法多样,大多数发表的指南在近年来均未被更新。我们试图制定一个全面的、无偏倚的、循证的TIA处理指南。方法:根据一种客观标准(可以预测在该研究领域中执业医师对专家提名的文献测量学方法)挑选出15名专家组成员。通过系统回顾检索到过去发表的指南,由专家对其中的推荐意见的质量进行独立评价。选择出质量最高的推荐意见,然后让专家组采用改良Delphi法通过多次问卷调查的方式进行修订,从而对新的修改达成共识。给专家们提供近期临床研究的系统评价,要求专家根据新的证据判断措辞修改的合理性并且根据证据等级和质量对最终的推荐意见进行评定。不允许专家在预期有可能存在任何利益冲突的专题方面提出推荐意见。结果:通过系统回顾检索到257个指南,其中有13篇文献包括的137条推荐意见符合所有纳入标准。需要6次重复的问卷调查对53条最终推荐意见的措辞达成共识。最终的推荐意见涉及TIA的初步处理、评价、内科治疗、外科治疗和危险因素控制。结论:对TIA患者医疗诊治的最终推荐意见强调了紧急评价和治疗的重要性。这种用于制定本指南的新方法是可行的,考虑到了快速更新并能减少偏倚。 | S. Claiborne Johnston Mai N. Nguyen-Huynh Miriam E. Schwarz Kate Fuller Christina Williams S. Andrew Josephsort Graeme J. Hankey Robert G. Hart Steven R. Levine Jose Biller Robert D. Brown Ralph L. Sacco L. Jaap Kappelle Peter J. Koudstaal Julien Bogousslavsky Louis R. Caplan Jan van Gijn Ale Algra Peter M. Rothwell Harold P. Adams Gregory W. Albers 李海峰(译) | 2007 | 国际脑血管病杂志2007，15，3： | 5 |
| 3 | Silent stroke in patients with transient isehemie attack or minor isehemie stroke显示文摘 | Hijdra A Algra A | 1992 | Stroke1992，23，9： | 1 |
| 4 | Early circulating levels of endothelial cell activation markers in aneurysmal subarachnoid haemorrhage:associations with cerebral ischaemic events and outcome显示文摘 | Frijns CJ Fijnheer R Algra A | 2006 | J Neurol Neurosurg Psychiatry2006，77，1： | 1 |
| 5 | Impaired glucose tolerance increase stroke risk in nondiabetic patients with transient ischemic attack or minor ischemic stroke显示文摘 | Sarah EV Sandee W Algra A | 2006 | Stroke2006，37，： | 1 |
| 6 | Effectiveness of neurosurgical clip application in patients with aneurismal subarachnoid hemorrhage 显示文摘 | Brilstra EH Algra A Rinkel GJ | 2002 | J Neurosurg2002，97，5： | 1 |
| 7 | Configuration of thecircle of Willis,direction of flow,and shape of the aneurysms asrisk factors for rupture of intracranial aneurysms 显示文摘 | de Rooij NK Velthuis BK Algra A | 2009 | J Neurol2009，256，1： | 1 |
| 8 | Electrocardiographic abnormalities and serum magnesium in patients with sunarachnoid hemorrhage显示文摘 | Van de WA Algra A Rinkel GJ | 2004 | Stroke2004，35，： | 1 |
| 9 | Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review显示文摘 | Hop JW Rinkel GJ Algra A | 1997 | Stroke1997，28，3： | 1 |
| 10 | Functional Recovery After Acute Myocardial Infarction显示文摘 | Robin Nijveldt Aernout M. Beek Alexander Hirsch Martin G. Stoel Mark B.M. Hofman Victor A.W.M. Umans Paul R. Algra Jos W.R. Twisk Albert C. van Rossum | 2008 | Journal of the American College of Cardiology2008，，3： | 1 |
| 11 | General movements:A window for early identification of children at high risk for developmental disorders显示文摘 | Hadders Algra M | 2004 | J Pediatr2004，145，2： | 1 |
| 12 | Cerebral small vessel disease and risk of death, ischemic stroke, and cardiac complications in patients with atherosclerotic disease:the Second Manifestations of ART erial disease-Magnetic Resonance (SMART-MR) study显示文摘 | Conijn MM Kloppenborg RP Algra A | 2011 | Stroke2011，42，： | 1 |
| 13 | Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials显示文摘 | Peter M Rothwell Michelle Wilson Carl-Eric Elwin Bo Norrving Ale Algra Charles P Warlow Tom W Meade | 2010 | 2010 (9754)2010，，9754： | 1 |
| 14 | Changes in functional outcome and quality of life in patients and earegivers after aneurismal sunarachnoid hemorrhage显示文摘 | Hop J Rinkel G Algra A | 2001 | Journal of Neurosurgery2001，95，： | 1 |
| 15 | Surgical decompression for space-occupying cerebral infarction(the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial):a multicentre,open,randomised trial显示文摘 | Hofmeijer J Kappelle LJ Algra A | 2009 | Lancet Neurol2009，8，4： | 1 |
| 16 | Epilepsy Surgery in tuberous sclerosis: a systematic review 显示文摘 | Jansen FE van Huffelen AC Algra A | 2007 | Epilepsia2007，48，8： | 1 |
| 17 | QT interval variables from 24-Hour electrocardiography and the two Year risk ofsudden death显示文摘 | Algra A Tijssen J G Roelandt J R | 1993 | Br Heart J1993，70，1： | 1 |
| 18 | Antiplatelet drugs in the secondary prevention after stroke:Differential efficacy in large versus small vessel disease/A subgroup analysis from ESPS 22显示文摘 | Ariesen MJ Algra A Kappelle LJ | 2006 | Stroke2006，37，1： | 1 |
| 19 | Paired Twins and{112}Morphology in GaP Nanowires显示文摘 | Algra R E Verheijen M A Feiner L F | 2010 | Nano Letters2010，10，7： | 1 |
| 20 | The position of oxygen adsorbed at the steps of a copper (410) surface studied with low energy ion scattering显示文摘 | Algra A J Suurmeijer E Boers A L | 1983 | Surf Sci1983，128，23： | 1 |
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