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| 1 | Non-compliant and compliant balloons for endovascular rescue therapy of cerebral vasospasm after spontaneous subarachnoid haemorrhage: experiences of a single- centre institution with radiological follow- up of the treated vessel segments显示文摘Background For endovascular rescue therapy(ERT)of cerebral vasospasm(CVS)due to spontaneous subarachnoid haemorrhage(sSAH),non-compliant(NCB)and compliant(CB)balloons are used with both balloon types bearing the risk of vessel injury due to specific mechanical properties.Although severe delayed arterial narrowing after transluminal balloon angioplasty(TBA)for CVS has sporadically been described,valid data concerning incidence and relevance are missing.Our aim was to analyse the radiological follow-up(RFU)of differently TBA-treated arteries(CB or NCB).Methods Twelve patients with utilisation of either NCB or CB for CVS were retrospectively analysed for clinical characteristics,ERT,functional outcome after 3 months and RFU.Compared with the initial angiogram,we classified delayed arterial narrowing as mild,moderate and severe(<30%,30%-60%,respectively>60% calibre reduction).Results Twenty-three arteries were treated with CB,seven with NCB.The median first RFU was 11 months after TBA with CB and 10 after NCB.RFU was performed with catheter angiography in 18 arteries(78%)treated with CB and in five(71%)after NCB;magnetic resonance angiography was acquired in five vessels(22%)treated with CB and in two(29%)after NCB.Mild arterial narrowing was detected in three arteries(13%)after CB and in one(14%)after NCB.Moderate or severe findings were neither detected after use of CB nor NCB.Conclusion We found no relevant delayed arterial narrowing after TBA for CVS after sSAH.Despite previous assumptions that CB provides for more dilatation in segments adjacent to CVS,we observed no disadvantages concerning long-term adverse effects.Our data support TBA as a low-risk treatment option. | Alexander Neumann Jan Küchler Claudia Ditz Kara Krajewski Jan Leppert Peter Schramm Hannes Schacht | 2021 | Stroke & Vascular Neurology2021,6,1: | 1 |
| 2 | Massive rotator cuff tears: functional outcome after debridement or arthroscopic partial repair显示文摘 | Alexander Berth Wolfram Neumann Friedemann Awiszus Géza Pap | 2010 | Journal of Orthopaedics and Traumatology2010,,1: | 1 |
| 3 | High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy显示文摘BACKGROUND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation therapy.Due to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor growth.Transarterial chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in LT.However,it remains unclear if one of those treatment options is superior.The analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by histopathology.AIM To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT alone.METHODS In this multicenter retrospective study,27 patients who received liver transplantation for HCC were analyzed.Patients received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver transplantation.Liver explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging therapies.Statistical analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-U tests.RESULTS Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and SBRT.There were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor lesions.Strikingly,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P value<0.001).CONCLUSION Our data suggests that a combination of TACE and SBRT increases the rate of complete histopathological response compared to TACE or SBRT alone in bridging to liver transplantation. | Ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens Neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas Umgelter Ursula Ehmer | 2021 | World Journal of Gastroenterology2021,27,24: | 1 |
| 4 | Urine catechoIamine concentration and psychophsical stress in elite tennis under practice and tournament conditions显示文摘 | Alexander Ferrauti Neumann G Weber K | 2001 | Journal Sports MED PHYS FITNESS2001,,41: | 1 |
| 5 | Cryoballoon ablation of paroxysmal atrial fibrillation: 5-year outcome after single procedure and predictors of success显示文摘 | Thomas Neumann Maciej Wójcik Alexander Berkowitsch Damir Erkapic Sergey Zaltsberg Harald Greiss Dimitri Pajitnev Stefan Lehinant J?rn Schmitt Christian W. Hamm Heinz F. Pitschner Malte Kuniss | 2013 | Europace2013,,8: | 1 |
| 6 | Aerobic photochemical oxidation in mesoporous Ti-MCM-41: epoxidation of alkenes and oxidation of sulfides显示文摘 | Alexander M. Khenkin Ronny Neumann | 2000 | Catalysis Letters (-)2000,,1: | 1 |
| 7 | Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (su PAR ) in acute liver failure显示文摘 | Alexander Koch Henning W. Zimmermann Nikolaus Gassler Christoph Jochum Ralf Weiskirchen Jan Bruensing Lukas Buendgens Hanna Dückers Tony Bruns Guido Gerken Ulf P. Neumann David H. Adams Christian Trautwein Ali Canbay Frank Tacke | 2014 | Liver Int2014,,9: | 1 |
| 8 | A sustainable development goal for the ocean and Coasts: Global ocean challenges benefit from regional initiatives supporting globally coordinated solutions显示文摘 | Martin Visbeck Ulrike Kronfeld-Goharani Barbara Neumann Wilfried Rickels J?rn Schmidt Erik van Doorn Nele Matz-Lück Alexander Proelss | 2014 | Marine Policy2014,,: | 1 |
| 9 | Circumferential Pulmonary Vein Isolation With the Cryoballoon Technique显示文摘 | Thomas Neumann Jürgen Vogt Burghard Schumacher Anja Dorszewski Malte Kuniss Hans Neuser Klaus Kurzidim Alexander Berkowitsch Marcus Koller Johannes Heintze Ursula Scholz Ulrike Wetzel Michael A.E. Schneider Dieter Horstkotte Christian W. Hamm Heinz-Friedr | 2008 | Journal of the American College of Cardiology2008,,4: | 1 |
| 10 | Embolization of an unusual metastatic site of hepatocellular carcinoma in the humerus显示文摘Hepatocellular carcinoma(HCC) is the fifth most common cancer in the world.This case documents an unusual metastatic presentation of HCC in the humerus.Preoperative palliative arterial embolization of the tumor was performed to arrest severe tumor bleeding caused by the biopsy.Embolization turned out to be useful also in limiting/preventing potential uncontrolled bleeding during subsequent amputation. | Andreas Hansch Rotraud Neumann Alexander Pfeil Ivan Marintchev Stefan Pfleiderer Mieczyslaw Gajda Werner A Kaiser | 2009 | World Journal of Gastroenterology2009,15,18: | 1 |
| 11 | How diverse were ferns in the Baltic amber forest?显示文摘Diverse temperate forest types and a high atmospheric humidity have recently been suggested for the Eocene source area of Baltic amber. However, ferns are astonishingly rare as inclusions in this amber, which is in contrast to other seed‐free land plants, fungi, and lichens. Moreover, the identities of some of the few described putative fern taxa are dubious, and some fossils were even assigned to the Paleozoic seed fern genera Alethopteris, Pecopteris and to the form genus Sphenopteris containing Paleozoic and Mesozoic fern‐like leaf fossils. Here, we review previously described fern inclusions from Baltic amber and identify further fern‐like leaf inclusions as belonging to the extant angiosperm genus Comptonia (sweet ferns, Myricaceae). We conclude that only one taxon, Matonia striata (Matoniaceae), can with confidence be identified as a Polypodiopsida representative. Although “Pecopteris” humboldtiana is so far only known as sterile foliage, its leaf morphology strongly suggests that also this taxon belongs to the Polypodiopsida rather than to any other tracheophyte lineage. We propose accommodating “Pecopteris” humboldtiana in the new genus Berendtiopteris.“Alethopteris” serrata and “Sphenopteris” phyllocladoides are not to be regarded as evidence of ferns from Baltic amber. Reinvestigation of the holotypes of these two taxa did not reveal to which tracheophyte lineages these fossils belong. We suggest that the scarcity of fern remains from Baltic amber may reflect both a relatively low fern diversity in the source area of the fossil resin, and an absence or rarity of epiphytic and climbing ferns as observed in modern temperate forest ecosystems. | Eva-Maria Sadowski Leyla J. Seyfullah Ledis Regalado Laura E. Skadell Alexander Gehler Carsten Grohn Christel Hoffeins Hans Werner Hoffeins Christian Neumann Harald Schneider Alexander R. Schmidt | 2019 | Journal of Systematics and Evolution2019,57,4: | 0 |