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| 1 | Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis. | Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels | 2010 | World Journal of Gastroenterology2010，16，6： | 11 |
| 2 | A taxonomic synopsis of the genus Campeiostachys Drobov显示文摘We have classified 11 species recently recognized as belonging to the genus Elymus into a resurrected and legitimate genus Campeiostachys Drobov according to the International Code of Botanical Nomenclature. Our action is based on the rationale of monophyly, discrimination, and practicality discussed in detail. Currently Elymus contains a vast number of species with different genomes which often, but not always, can be differentiated by cytological and molecular features, but are difficult to separate by traditional morphology, although an effort to do so is detailed and discussed. This difficulty can be attributed to the dominance effect of a particular genome on the other genome(s) present. Campeiostachys, with genome constitution StStHHYY, is a recent addition to a number of genera recently segregated out of Elymus, i.e. Douglasdeweya (StStPP), Kengyilia (StStPPYY), and Roegneria (StStYY, StStStStYY). A key to Campeiostachys taxa is provided, along with taxa descriptions, distribution, nomenclature, and cytology. Nineteen nomenclatural novelties, or combinations, resulted from this work, 10 species names, and nine varietal names. | Bemard R. BAUM jun-Liang YANG Chi YEN Alex V AGAFONOV | 2011 | Journal of Systematics and Evolution2011，49，2： | 3 |
| 3 | Single crystal growth of SiGe by the Czochralski technique显示文摘 | ABROSIMOV N V ROSSOLENKO S N ALEX V | 1996 | J Crystal Growth1996，，166： | 1 |
| 4 | Nanopomus Au: A high yield strength material显示文摘 | Juergen B Andrea M H Alex V H | 2005 | J Appl Phys2005，97，02： | 1 |
| 5 | Control of hypothalamic orexin neurons by acid and CO2显示文摘 | Rhiannan HW Lise TJ Alex V | 2007 | PNAS2007，104，10： | 1 |
| 6 | Oxide contacts in organic photovoltaics: characterization and control of near-surface composition in indium-tin oxide (ITO) electrodes显示文摘 | NEAL R ARMSTRONG P ALEX V | 2009 | Ace Chem Res2009，42，11： | 1 |
| 7 | Support Vector Method for Function Approximation Regression Estimation and Signal Processing 显示文摘 | Vapnik V Golowich S Alex S | 1996 | Advances in Neural Information Processing Systems1996，9，： | 1 |
| 8 | Comparison of plasminogen binding and activation on extracellular matrices produced by vascular smooth muscle and endothelial cells 显示文摘 | M Sharon Stack Alex R Rinehart Salvatore V Pizzo | 1994 | Eur J Biochem1994，226，3： | 1 |
| 9 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink David N Gomes Tara Ko Dennis T Szmitko Paul E Austin Peter C Tu Jack V Henry David A Kopp Alex Mamdani Muhammad M | 2009 | Canadian Medical Association. Journal2009，，7： | 1 |
| 10 | Improvement heuristics for the vehicle routing problem based on simulated annealing显示文摘 | Alex V B | 1995 | European Journal of Operational Research1995，86，5： | 1 |
| 11 | Studies on epoxidized rubber seed oil as plasticizer for acrylonitrile butadiene rubber显示文摘 | JOSEPH R ALEX R VINOD V S | 2003 | Journal of Applied Polymer Science2003，89，3： | 1 |
| 12 | Effects on surface morphology of ep- itaxial Y203 layers on Si (001) after post growth annealing 显示文摘 | loannou-Sougleridis V Constantoudis V Alexe M Scholz R Vellianitis G Dimoulas A | 2004 | Thin Solid Films2004，468，12： | 1 |
| 13 | Effects on surface morphology of epitaxial Y2O3 layers on Si (001) after postgrowth annealing 显示文摘 | Sougleridisa V I Constantoudis V Alexe M | 2004 | Thin Solid Films2004，468，： | 1 |
| 14 | Cumulative viral evolutionary changes in chronic hepatitis B virus infection precedes hepatitis B e antigen seroconversion显示文摘 | Yan Cheng Stephane Guindon Allen Rodrigo Lin Ying Wee Masafumi Inoue Alex J V Thompson Stephen Locarnini Seng Gee Lim | 2013 | Gut2013，，9： | 1 |
| 15 | Histidine and aspartate phosohorylatron :two-component systems and the limits of homology显示文摘 | Swanson R V Alex L A Simon M I | 1994 | Trends Biochem Sci1994，19，： | 1 |
| 16 | Measuring the objectness o fimage w indows显示文摘 | Alexe B Deselaers T Ferrari V | 2012 | IEEE Transactions on Pattern Analysis andMachine Intelligence2012，34，11： | 1 |
| 17 | Studies on the cure and mechanical properties of blends of natural rubber with dichloro- carbene modified styrene-butadiene rubber and chloroprene rubber显示文摘 | Ramesana M T Alex R Khanh N V | 2005 | Reactive and Functional Polymers2005，62，1： | 1 |
| 18 | Crystal structure of a GCN5-related N-acety ltransferase:serratia marcescens aminoglycoside 3-N-acetyltransferase显示文摘 | Eva w Alex V Yasutaka M | 1998 | Cell1998，，94： | 1 |
| 19 | Measuring the object- ness of image windows 显示文摘 | ALEXE B DESELAERS T FERRARI V | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，11： | 1 |
| 20 | Genome rearrangements, deletions, and amplifications in the natural population of Bartonella henselae 显示文摘 | HILLEVI L OLGA V ALEX M | 2006 | Journal of Bacteriology2006，188，21： | 1 |
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