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4篇 您的检索式:作者名="Alessio Papi"
    题名 作者 年代 出处 被引量
1Role of nuclear receptors in breast cancer stem cells显示文摘The recapitulation of primary tumour heterogenity and the existence of a minor sub-population of cancer cells,capable of initiating tumour growth in xenografts on serial passages, led to the hypothesis that cancer stem cells(CSCs) exist. CSCs are present in many tumours, among which is breast cancer. Breast CSCs(BCSCs) are likely to sustain the growth of the primary tumour mass, as wellas to be responsible for disease relapse and metastatic spreading. Consequently, BCSCs represent the most significant target for new drugs in breast cancer therapy. Both the hypoxic condition in BCSCs biology and proinflammatory cytokine network has gained increasing importance in the recent past. Breast stromal cells are crucial components of the tumours milieu and are a major source of inflammatory mediators. Recently, the antiinflammatory role of some nuclear receptors ligands has emerged in several diseases, including breast cancer. Therefore, the use of nuclear receptors ligands may be a valid strategy to inhibit BCSCs viability and consequently breast cancer growth and disease relapse.Alessio Papi Marina Orlandi 2016World Journal of Stem Cells2016,8,3:2
2RXRγ and PPARγ ligands in combination to inhibit proliferation and invasiveness in colon cancer cells显示文摘Alessio Papi Paola Rocchi Anna Maria Ferreri Marina Orlandi 2010Cancer Letters2010,,1:1
3A RXR Ligand 6-OH-11-O-Hydroxyphenanthrene with Antitumour Properties Enhances (?)-Epigallocatechin-3-gallate Activity in Three Human Breast Carcinoma Cell Lines显示文摘Fulvia Farabegoli Marzia Govoni Carmen Ciavarella Marina Orlandi Alessio Papi Beatrice Charreau 2014BioMed Research International2014,,:1
4Slug/β-Catenin–Dependent Proinflammatory Phenotype in Hypoxic Breast Cancer Stem Cells显示文摘Gianluca Storci Sara Bertoni Sabrina De Carolis Alessio Papi Marina Nati Claudio Ceccarelli Chiara Pirazzini Paolo Garagnani Alberto Ferrarini Genny Buson Massimo Delledonne Michelangelo Fiorentino Elisa Capizzi Elisa Gruppioni Mario Taffurelli Donatella 2013The American Journal of Pathology2013,,5:1
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