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| 1 | Early and late complications associated with transcatheter occlusion of secundum atrial septal defect显示文摘 | Massimo Chessa Mario Carminati Gianfranco Butera Roberta Margherita Bini Manuela Drago Luca Rosti Alessandro Giamberti Giuseppe Pomè Eduardo Bossone Alessandro Frigiola | 2002 | Journal of the American College of Cardiology2002，，6： | 2 |
| 2 | Natural heme oxygenase-1 inducers in hepatobiliary function显示文摘Many physiological effects of natural antioxidants,their extracts or their major active components,have been reported in recent decades.Most of these compounds are characterized by a phenolic structure,similar to that of α-tocopherol,and present antioxidant proper-ties that have been demonstrated both in vitro and in vivo.Polyphenols may increase the capacity of en-dogenous antioxidant defences and modulate the cellu-lar redox state.Changes in the cellular redox state may have wide-ranging consequences for cellular growth and differentiation.The majority of in vitro and in vivo studies conducted so far have attributed the protective effect of bioactive polyphenols to their chemical reac-tivity toward free radicals and their capacity to prevent the oxidation of important intracellular components.However,in recent years a possible novel aspect in the mode of action of these compounds has been sug-gested; that is,the ultimate stimulation of the heme oxygenase-1 (HO-1) pathway is likely to account for the established and powerful antioxidant/anti-inflam-matory properties of these polyphenols.The products of the HO-catalyzed reaction,particularly carbon mon-oxide (CO) and biliverdin/bilirubin have been shown to exert protective effects in several organs against oxidative and other noxious stimuli.In this context,it is interesting to note that induction of HO-1 expression by means of natural compounds contributes to protec-tion against liver damage in various experimental mod-els.The focus of this review is on the significance of targeted induction of HO-1 as a potential therapeutic strategy to protect the liver against various stressors in several pathological conditions. | Giovanni Li Volti David Sacerdoti Claudia Di Giacomo Maria Luisa Barcellona Antonio Scacco Paolo Murabito Antonio Biondi Francesco Basile Diego Gazzolo Raul Abella Alessandro Frigiola Fabio Galvano | 2008 | World Journal of Gastroenterology2008，14，40： | 2 |
| 3 | Risk of Assessing Mortality Risk in Elective Cardiac Operations: Age, Creatinine, Ejection Fraction, and the Law of Parsimony显示文摘 | Marco Ranucci Serenella Castelvecchio Lorenzo Menicanti Alessandro Frigiola Gabriele Pelissero | 2009 | Circulation2009，，24： | 1 |
| 4 | Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience显示文摘 | Santi Trimarchi Christoph A. Nienaber Vincenzo Rampoldi Truls Myrmel Toru Suzuki Rajendra H. Mehta Eduardo Bossone Jeanna V. Cooper Dean E. Smith Lorenzo Menicanti Alessandro Frigiola Jae K. Oh Michael G. Deeb Eric M. Isselbacher Kim A. Eagle | 2004 | The Journal of Thoracic and Cardiovascular Surgery2004，，1： | 1 |
| 5 | Transcatheter Closure of Perimembranous Ventricular Septal Defects显示文摘 | Gianfranco Butera Mario Carminati Massimo Chessa Luciane Piazza Angelo Micheletti Diana Gabriella Negura Raul Abella Alessandro Giamberti Alessandro Frigiola | 2007 | Journal of the American College of Cardiology2007，，12： | 1 |
| 6 | Treatment of isolated secundum atrial septal defects: Impact of age and defect morphology in 1,013 consecutive patients显示文摘 | Gianfranco Butera Enrico Romagnoli Mario Carminati Massimo Chessa Luciane Piazza Diana Negura Alessandro Giamberti Raul Abella Giuseppe Pomè Claudia Condoluci Alessandro Frigiola | 2008 | American Heart Journal2008，，4： | 1 |
| 7 | Diagnostic Yield of Non-Invasive Testing in Patients with Anomalous Aortic Origin of Coronary Arteries:A Multicentric Experience显示文摘Background:Anomalous aortic origin of a coronary artery(AAOCA)is a congenital heart disease with a 0.3%−0.5%prevalence.Diagnosis is challenging due to nonspecific clinical presentation.Risk stratification and treatment are currently based on expert consensus and single-center case series.Methods:Demographical and clinical data of AAOCA patients from 17 tertiary-care centers were analyzed.Diagnostic imaging studies(Bidimensional echocardiography,coronary computed tomography angiography[CCTA]were collected.Clinical correlations with anomalous coronary course and origin were evaluated.Results:Data from 239 patients(42%males,mean age 15 y)affected by AAOCA were collected;154 had AAOCA involving the right coronary artery(AAORCA),62 the left(AAOLCA),23 other anomalies.211(88%)presented with an inter-arterial course.Basal electrocardiogram(ECG)was abnormal in 37(16%).AAOCA was detected by transthoracic echocardiography and CCTA in 53%and 92%of patients,respectively.Half of the patients reported cardiac symptoms(119/239;50%),mostly during exercise in 121/178(68%).An ischemic response was demonstrated in 37/106(35%)and 16/31(52%)of patients undergoing ECG stress test and stress-rest single positron emission cardiac tomography.Compared with AAORCA,patients with AAOLCA presented more frequently with syncope(18%vs.5%,P=0.002),in particular when associated with inter-arterial course(22%vs.5%,P<0.001).Conclusion:Diagnosis of AAOCA is a clinical challenge due to nonspecific clinical presentations and low sensitivity of first-line cardiac screening exams.Syncope seems to be strictly correlated to AAOLCA with inter-arterial course. | Alberto Cipriani Pietro Bernardo Dall’Aglio Laura Mazzotta Domenico Sirico George Sarris Mark Hazekamp Thierry Carrel Alessandro Frigiola Vladimir Sojak Mauro Lo Rito Jurgen Horer Regine Roussin Julie Cleuziou Bart Meyns Jose Fragata Helena Telles Anastasios C.Polimenakos Katrien Francois Altin Veshti Jukka Salminen Alvaro Gonzalez Rocafort Matej Nosal Eleftherios Protopapas Roberto Tumbarello Patrizio Sarto Cinzia Pegoraro Raffaella Motta Giovanni Di Salvo Domenico Corrado Vladimiro LVida Massimo A.Padalino | 2022 | Congenital Heart Disease2022，17，4： | 0 |
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