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| 1 | Regulation of gene expression in chickens by heat stress显示文摘High ambient temperatures are a critical challenge in the poultry industry which is a key producer of the animal-based food.To evaluate heat stress levels,various parameters have been used,including growth rates,blood metabolites,and hormones.The most recent advances have explored expression profiling of genes that may play vital roles under stress.A high ambient temperature adversely affects nutrient uptake and is known to modulate the expression of genes encoding for sodium-dependent glucose transporters,glucose transporters,excitatory amino acid transporters,and fatty acidbinding proteins which are responsible for the absorption of macronutrients in the intestine.Various defensive activities are stimulated to protect the cell of different tissues from the heat-generated stress,including expression of early stress response genes coding for heat shock protein(HSP),c-FOS like protein,brain-derived neurotrophic factor(BDNF),and neuronal nitric oxide synthase(nNOS);antioxidant enzyme genes such as superoxide dismutase(SOD),catalase(CAT),and nicotinamide adenine dinucleotide phosphate oxidase(NOX4);and immune-related genes such as cytokines and toll-like receptors(TLRs).The potential role of HSPs in protecting the cell from stress and their presence in several tissues make them suitable markers to be evaluated under heat stress.BDNF and c-FOS genes expressed in the hypothalamus help cells to adapt to an adverse environment.Heat causes damage to the cell by generating reactive oxygen species(ROS).The NOX4 gene is the inducer of ROS under heat stress,which is in turns controlled by antioxidant enzymes such as SOD and CAT.TLRs are responsible for protecting against pathogenic attacks arising from enhanced membrane permeability,and cytokines help in controlling the pathogen and maintaining homeostasis.Thus,the evaluation of nutrient transporters and defense mechanisms using the latest molecular biology tools has made it possible to shed light on the complex cellular mechanism of heat-stressed chickens.As the impacts of heat stress on the above-mentioned aspects are beyond the extent to which the reduced growth performance could be explained,heat stress has more specific effects on the regulation of these genes than previously thought. | Akshat Goel Chris Major Ncho Yang-Ho Choi | 2021 | Journal of Animal Science and Biotechnology2021,12,2: | 2 |
| 2 | Systematic Review of Randomized and Nonrandomized Trials of the Clinical Response and Outcomes of Neoadjuvant Systemic Chemotherapy for Resectable Colorectal Liver Metastases显示文摘 | Terence C. Chua BScMed (Hons) Akshat Saxena BMedSc Winston Liauw MBBS MMed Sci Adel Kokandi MBBS David L. Morris MD PhD | 2010 | Annals of Surgical Oncology2010,,2: | 2 |
| 3 | Dimethoxymethane production via CO_(2)hydrogenation in methanol over novel Ru based hierarchical BEA显示文摘Dimethoxymethane(DMM),a diesel blend fuel,is being researched with high interest recently due to its unique fuel properties.It is commercially produced via a two step-process of methanol oxidation to make formaldehyde,followed by its condensation with methanol.This study presents a one-pot method of DMM synthesis from methanol mediated carbon dioxide hydrogenation over novel heterogeneous catalysts.The effect of catalyst pore structure was investigated by synthesizing 3 wt%Ru over novel hierarchical zeolite beta(HBEASX)and comparing against Ru doped commercial zeolite beta(CBEA)and desilicated hierarchical zeolite beta(HBZDS).The results showed that 3%Ru/HBEASX provided the best activity for DMM production due to its large average pore size.It also showed the decisive role of SiO_(2)/Al_(2)O_(3)molar ratio,with SiO_(2)/Al_(2)O_(3)=75 providing the highest DMM yield of 13.2 mmol/gcat.LMeOH with ca.100%selectivity.The activity of 3%Ru/HBEAS3 after 5 recycle steps demonstrated the reusability of this catalyst. | Waqar Ahmad Fan Liang Chan Abhijit Shrotri Yayati Naresh Palai Huanting Wang Akshat Tanksale | 2022 | Journal of Energy Chemistry2022,31,3: | 2 |
| 4 | A systematic review on the safety and efficacy of yttrium-90 radioembolization for unresectable, chemorefractory colorectal cancer liver metastases显示文摘 | Akshat Saxena Lourens Bester Leonard Shan Marlon Perera Peter Gibbs Baerbel Meteling David L. Morris | 2014 | Journal of Cancer Research and Clinical Oncology2014,,4: | 2 |
| 5 | A systematic review and meta-analysis on the impact of pre-operative neutrophil lymphocyte ratio on long term outcomes after curative intent resection of solid tumours显示文摘 | Ashvin Paramanathan Akshat Saxena David Lawson Morris | 2013 | Surgical Oncology2013,,: | 2 |
| 6 | An improved method for the determination of NADH oxidase in the presence of NADH peroxidase in lactic acid bacteria 显示文摘 | Akshat Talwalkar | 2003 | Journal of Microbiological Methods2003,52,: | 1 |
| 7 | A review of catalytic hy- drogen production processes from biomass 显示文摘 | Akshat T Jorge N B Gao Q M L | 2010 | Renewable and Sustai nable Energy Reviews2010,14,: | 1 |
| 8 | BRCA 1 mutation site may be linked with nuclear DNA ploidy in BRCA 1- mutated ovarian carcinomas显示文摘 | Morteza Aghmesheh Akshat Saxena Farshid Niknam | 2015 | Asia Pac J Clin Oncol2015,11,2: | 1 |
| 9 | A Critical Evaluation of Risk Factors for Complications After Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy for Colorectal Peritoneal Carcinomatosis显示文摘 | Akshat Saxena Tristan D. Yan David L. Morris | 2010 | World Journal of Surgery2010,,1: | 1 |
| 10 | Clinicopathologic and Treatment-Related Factors Influencing Recurrence and Survival after Hepatic Resection of Intrahepatic Cholangiocarcinoma: A 19-Year Experience from an Established Australian Hepatobiliary Unit显示文摘 | Akshat Saxena Terence C. Chua Anik Sarkar Francis Chu David L. Morris | 2010 | Journal of Gastrointestinal Surgery2010,,7: | 1 |
| 11 | Progression and survival results after radical hepatic metastasectomy of indolent advanced neuroendocrine neoplasms (NENs) supports an aggressive surgical approach显示文摘 | Akshat Saxena Terence C. Chua Anik Sarkar Francis Chu Winston Liauw Jing Zhao David L. Morris | 2011 | Surgery2011,,2: | 1 |
| 12 | Hepatectomy and resection of concomitant extrahepatic disease for colorectal liver metastases – A systematic review显示文摘 | Terence C. Chua Akshat Saxena Winston Liauw Francis Chu David L. Morris | 2011 | European Journal of Cancer2011,,12: | 1 |
| 13 | Yttrium-90 Radiotherapy for Unresectable Intrahepatic Cholangiocarcinoma: A Preliminary Assessment of This Novel Treatment Option显示文摘 | Akshat Saxena BMedSc Lourens Bester MBChB BSc (Hons) FRANZCR Terence C. Chua BSc (Med) (Hons) Francis C. Chu MBBS FRACS David L. Morris MD PhD | 2010 | Annals of Surgical Oncology2010,,2: | 1 |
| 14 | Factors Predicting Response and Survival After Yttrium-90 Radioembolization of Unresectable Neuroendocrine Tumor Liver Metastases: A Critical Appraisal of 48 Cases显示文摘 | Akshat Saxena Terence C. Chua Lourens Bester Adel Kokandi David L. Morris | 2010 | Annals of Surgery2010,,: | 1 |
| 15 | Yttrium-90 Radioembolization for Unresectable, Chemoresistant Breast Cancer Liver Metastases: A Large Single-Center Experience of 40 Patients显示文摘 | Akshat Saxena Jada Kapoor Baerbel Meteling David L. Morris Lourens Bester | 2014 | Annals of Surgical Oncology2014,,: | 1 |
| 16 | Yttrium-90 Radiotherapy for Unresectable Intrahepatic Cholangiocarcinoma: A Preliminary Assessment of This Novel Treatment Option显示文摘 | Akshat Saxena BMedSc Lourens Bester MBChB BSc (Hons) FRANZCR Terence C. Chua BSc (Med) (Hons) Francis C. Chu MBBS FRACS David L. Morris MD PhD | 2010 | Annals of Surgical Oncology2010,,2: | 1 |
| 17 | Acute pancreatitis显示文摘 | Priyadarshini Pal Singh Akshat Kumar Ajay Kumar | 2014 | Apollo Medicine2014,,: | 1 |
| 18 | Pancreatic hydatid cyst masquerading as a choledochal cyst显示文摘 | Ankur Mandelia Akshat Wahal Shailesh Solanki M. Srinivas Veereshwar Bhatnagar | 2012 | Journal of Pediatric Surgery2012,,11: | 1 |
| 19 | Generalized ERSS tree model: Revisiting working sets显示文摘 | Ricardo Koller Akshat Verma Raju Rangaswami | 2010 | Performance Evaluation2010,,11: | 1 |
| 20 | Workload management for power efficiency in virtu- alized data centers显示文摘 | Gargi Dasgupta Amit Sharma Akshat Venna | 2011 | Communications of the ACM2011,54,7: | 1 |