|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions显示文摘癌症房间被知道经历新陈代谢的 reprogramming 然而,支撑幸存和快速的增长 oncogenic 损害怎么在各种各样的强调条件下面协调新陈代谢的开关,尚待充分被阐明。这里,我们显示出葡萄糖或夫酸安的那剥夺,为癌症房间的二主要营养来源,被伴随由的戏剧性地激活的丝氨酸生合成小径(SSP ) 提高了 cMyc 表示。我们进一步鉴别那 cMyc 刺激了 SSP 激活由 transcriptionally 多重 SSP 酶的 upregulating 表示。而且,我们证明 cMyc 便于的 SSP 激活导致了提高的谷胱甘肽(GSH ) 生产,房间周期前进和 nucleic 酸合成,它在剥夺营养素的条件下面特别为房间幸存和增长是必要的。我们进一步揭开了那 phosphoserine 磷酸酶( PSPH ), SSP 小径的最后的限制率的酶,在 vitro 并且在 vivo 为 驾驶cMyc 的癌症前进是批评的,并且重要地, PSPH 的异常表示高度在 hepatocellular 与死亡被相关癌( HCC )病人,一般来说建议在这 调整cMyc 的酶,或 SSP 激活之间的一种潜在的原因的关系,并且癌症开发。一起拿,我们的结果表明 cMyc 的那异常表情导致提高的 SSP 激活,新陈代谢的开关的必要部分,在剥夺营养素的条件下面便于癌症前进。 | Linchong Sun Libing Song Qianfen Wan Gongwei Wu Xinghua Li Yinghui Wang Jin Wang Zhaoji Liu Xiuying Zhong Xiaoping He Shengqi Shen Xin Pan Ailing Li Yulan Wang Ping Gao Huiru Tang Huafeng Zhang | 2015 | Cell Research2015，25，4： | 33 |
| 2 | Theoretical and Experimental Study on Reaction Coupling: Dehydrogenation of Ethylbenzene in the Presence of Carbon Dioxide显示文摘到苯乙烯(圣) 的乙苯(EB ) 的除氢作用面对 CO2,在 EB,除氢作用被结合反向的水气体移动(RWGS ) ,通过理论分析和试验性的描述广泛地被调查。联合的反应证明了比在几个方面的单个除氢作用优异。热力学的分析建议 EB 的那平衡变换能被由于从除氢作用生产的氢的同时的消除联合的反应极大地改进。催化测试证明了与某些倡导者一起在活性炭或 Al2O3 上支持的那个熨斗和钒是为这个联合过程的潜在的催化剂。铁和钒的催化剂在反应机理是不同的,尽管圣产量总是在各种各样的催化剂上与 CO2 变换被联系。当一步舞小径在 V/Al2O3 上统治反应时,二拍子的圆舞小径在 Fe/Al2O3 上在联合过程起一个重要作用。科克免职和活跃部件的深减小是催化剂释放的主要原因。CO2 能通过在联合过程在高原子价保存活跃种类有效地减轻催化剂释放,尽管它不能压制焦炭免职。给词调音:联合的反应;乙苯除氢作用;苯乙烯;二氧化碳;水气体移动;反应机理; | Shuwei Chen Zhangfeng Qin Ailing Sun Jianguo Wang | 2006 | Journal of Natural Gas Chemistry2006，15，1： | 5 |
| 3 | Growth Characteristics and Kinetics of Niobium Carbide Coating Obtained on AISI 52100 by Thermal-reactive Diffusion Technique显示文摘Niobium carbide coating was produced by thermal-reactive diffusion technique on AISI 52100 steel in salt bath at 1 123 K, 1 173 K, and 1 223 K for 1, 2, 4, and 6 hours. The salt consisted of borax, sodium fl uoride, boron carbide, and niobium pentoxide. The presence of NbC phase on the steel surface was confi rmed by X-ray diffraction analysis. Microscopic observation showed that niobium carbide coating formed on the substrate was smooth and compact. There was a distinct and fl at interface between the coating and substrate. The micro-hardness of niobium carbide coating was 2892±145HV. The thickness of coating ranged from 1.6 μm to 14μm. The forming kinetics of niobium carbide coating was revealed. Moreover, a contour diagram derived from experimental data was graphed for correct selection of process parameters. Some mathematical equations were built for predicting the coating thickness with predetermined processing temperature and time. The results showed that these mathematical equations are very practical as well as the kinetics equation. | 严绍进 王洪福 SUN Qikun HE Peng PANG Chengang WANG Huachang WANG Ailing | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，4： | 5 |
| 4 | Photoluminescence and defect evolution of nano-ZnO thin films at low temperature annealing显示文摘Nano-ZnO thin films composed of nanoparticles with sizes of 10-16 nm on silicon substrates at low temperature were prepared by sol-gel method.By placing the nano-ZnO thin films at room temperature or annealing at 100°C in air for 10 h intermittently,within a total 70 h annealing time,the evolution of PL spectra of the nano-ZnO thin films were studied in detail.As the annealing time increases,the PL peaks shift from violet to blue and green bands.The PL peaks at violet and blue bands decrease with the annealing time,but the PL peaks at green band are opposite.The PL spectra are related to the defects in the nano-ZnO thin films.The PL peaks positioned at 430 nm are mainly related to defects of zinc interstatials(Zni),oxygen vacancies and(Vo);the ones at 420 nm to oxygen interstitials(Oi),Zinc vacancies(Vzn),Zni ;and the ones at 468 nm to Vzn,Zni,and charged oxygen interstatials(Vo+).The green luminescence is related to Oi,Vo and Zni.The evolutions of PL spectra and the defects are also related to the concentrations of Zn in the thin films,the thicknesses of the films and the annealing time.For the films with 0.5 M and 1.0 M Zn concentrations,after 20 h and 30 h annealing in air at 100°C,respectively,either placing them in air at room temperature or continuing anneal in air at 100°C,the PL spectra are stable.Under the low temperature annealing,Zni decreases with the annealing time,and Oi increases.Sufficient Oi favors to keep the nano-ZnO thin films stable.This result is important to nano-ZnO thin films as electron transport layers in inverted or tandem organic solar cells. | YANG AiLing YANG Yun ZHANG ZhenZhen BAO XiChang YANG RenQiang LI ShunPin SUN Liang | 2013 | Science China(Technological Sciences)2013，56，1： | 5 |
| 5 | Microstructure and penetration behavior of electroformed copper liners of shaped charges during explosive detonation deformation显示文摘The microstructure in the electroformed copper liners of shaped charges prepared with different electrolytes was studied by Scanning Electron Microscopy (SEM) and Electron Backscattering Kikuchi Pattern (EBSP) methods. SEM observations revealed the existence of columnar grains in electroformed copper liners of shaped charges formed by electrolyte without any additive and the average grain size is about 3 μm. When an additive is introduced to the electrolyte, the grains formed in the copper liners become equiaxed and finer. EBSP results show that the columnar grain grown during electroformation has the most preferential growth direction, whereas a micro-texture does not exit in the specimen prepared by electrolyte with the additive. Further, explosive detonation deformation experiments show that penetration depth is dramatically improved when the electroformed copper liners of shaped charges exhibit equiaxed grains. | Ailing Fan Wenhuai Tian Qi Sun Baoshen Wang | 2006 | Journal of University of Science and Technology Beijing2006，13，1： | 4 |
| 6 | Synthesis of hexagonal and triangular Fe3O4 nanosheets via seed-mediated solvothermal growth显示文摘 | Chunhui Li Ruixue Wei Yanmin Xu Ailing Sun Liuhe Wei | 2014 | Nano Research2014，7，4： | 2 |
| 7 | 增温和放牧对高寒草甸凋落物分解及其养分释放的影响不依赖于凋落物品质显示文摘在放牧生态系统中,增温、放牧和调落物品质共同决定着凋落物分解和养分释放。然而,在以往的研究中这些因子的效应通常被单独地研究。在本研究中,我们在青藏高原高寒草甸开展了一个昼夜非对称增温和中度放牧两因子的调落物分解试验。从每个处理中收集了调落物样品,这些调落物一部分放在它们的来源处理小区,另一部分放在其他处理小区以此来探究增温、放牧以及调落物品质对调落物分解和养分释放的影响。研究结果表明,增温而不是放牧显著增加了调落物质量的损失、单位面积全碳、全氮以及全磷含量的损失,这主要是因为增温增加了落物生物量和分解速率。然而,尽管同时增温放牧处理也加快了调落物分解速率,但由于降低了调落物生物量,所以增温放牧处理并没有显著影响单位面积的凋落物碳和养分释放量。相比木质素含量和碳氮比而言,季节性土壤平均温度能够更好地预测调落物分解速率。增温和放牧对调落物分解存在交互作用,但它们和调落物品质对调落物的影响均不存在交互作用。单位面积的总氮释放的温度敏感性要高于总磷。因此,我们的结果表明,增温对调落物分解以及养分释放的影响要显著大于调落物品质变化对其分解的影响。在高寒草甸,氮释放的增加可能会间接导致土壤磷有效性的缺乏。 | Bowen Li Wangwang Lv Jianping Sun Lirong Zhang Lili Jiang Yang Zhou Peipei Liu Huan Hong Qi Wang Wang A Suren Zhang Lu Xia Zongsong Wang Tsechoe Dorji Ailing Su Caiyun Luo Zhenhua Zhang Shiping Wang | 2022 | Journal of Plant Ecology2022，15，5： | 1 |
| 8 | Ethylbenzene dehydrogenation in the presence of carbon dioxide over alumina supported catalysis显示文摘 | SUN AILING QIN ZHANGFENG CHEN SHUWEi | 2004 | Catalysis Today2004，9395，： | 1 |
| 9 | Isolation and purification of coumarin compounds from Cortex fraxinus by high-speed counter-current chromatography 显示文摘 | Liu Renmin Sun Qinghua Sun Ailing | 2005 | Journal of chromatography A2005，1072，2： | 1 |
| 10 | Reparative isolation and purification of hydroxyanthraquinones and cinnamic acidfrom the Chinese medicinal herb Rheum officinale baill, by high-speed countercurrent chromatography 显示文摘 | Liu Renmin Li Aifeng Sun Ailing | 2004 | Journal of Chromatography A2004，1052，： | 1 |
| 11 | Isolation and purification of coumarin compounds from Cortex Fraxinus by high - speed counter - current chromatography显示文摘 | Renmin Liu Qinghua Sun Ailing Sun | 2005 | Journal of Chromatography A2005，1072，： | 1 |
| 12 | Effect of PAC addition on MBR process for drinking water treatment 显示文摘 | Sagbo Omer Sun Yaxi Hao Ailing Gu Ping | 2008 | Separation and PurificationTechnology2008，58，2008： | 1 |
| 13 | Preparative isolation and purification of psoralen and isopsoralen from Psoralea corylifolia by high-speed counter-current chromatography显示文摘 | Renmin Liu Aifeng Li Ailing Sun Lingyi Kong | 2004 | Journal of Chromatography A2004，，1： | 1 |
| 14 | Reaction Coupling of Ethylbenzene Dehydrogenation with Nitrobenzene Hydrogenation显示文摘 | Ailing Sun Zhangfeng Qin Jianguo Wang | 2002 | Catalysis Letters (-)2002，，1： | 1 |
| 15 | Effect of PAC addition on MBR process for drinking water treatment 显示文摘 | Sagbo Omer Sun Yaxi Hao Ailing | 2008 | Sep Purif Technol2008，58，3： | 1 |
| 16 | Lower Triassic conodont sequence in Chaohu, Anhui Province, China and its global correlation显示文摘 | Zhao Laishi Michael J. Orchard Tong Jinnan Sun Zhiming Zuo Jinxun Zhang Suxin Yun Ailing | 2007 | Palaeogeography Palaeoclimatology Palaeoecology2007，，1： | 1 |
| 17 | Effect of PAC addition on MBR process for drinking water treatment 显示文摘 | SAGBO O SUN Yaxi HAO Ailing | 2008 | Separation and Purification Technology2008，，58： | 1 |
| 18 | Separation and Purifica- tion of Rutin and Acaciin from the Chinese Medicinal Herb Her- ba Cirsii by Combination of Macroporous Absorption Resin and High - Speed Counter - Current Chromatography 显示文摘 | Li Meng Renmin Liu Ailing Sun | 2009 | Journal of Chromatographic Science2009，47，： | 1 |
| 19 | Effect of PAC additionon MBR process for drinking water treatment显示文摘 | Sagbo Omer Sun Yaxi Hao Ailing | 2008 | Separation andPurification Technology2008，58，： | 1 |
| 20 | Comparative Study of Ship-in-a-Bottle and Anchored Heterogenized Mn Complexes显示文摘 | Yang Guoyu Sun Ailing Zhou Wenfeng Zhu Hailin Jiang Denggao | 2007 | Catalysis Letters (-)2007，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员