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| 1 | Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients显示文摘AIM:To investigate prevalence,type and time of onset of extraintestinal manifestations(EIMs)in a series of Italian inflammatory bowel disease(IBD)patients.METHODS:Data of 811 IBD consecutive patients,first referred to our Centre from 2000 to 2011,were retrospectively evaluated.RESULTS:Eight hundred and eleven IBD patients(437M,374 F)were studied:595 ulcerative colitis(UC)(73.4%)and 216 Crohn’s disease(CD)(26.6%).Among these,329(40.6%)showed EIMs:210 UC(35.3%)and119 CD(55.1%)(P<0.0001).Considering the time of the diagnosis of IBD,37 EIMs(11.2%)were developed before,229(69.6%)after and 63(19.2%)were simultaneous.The type of EIM were as follows:240 musculoskeletal(29.6%),in 72 CD patients and in 168 UC(P<0.0001);47 mucocutaneous(5.8%),in 26 CD and in21 UC(P=0.0049);26 ocular(3.2%),in 16 CD and in10 UC(CD 7.4%vs UC 1.7%,P=0.0093);6 hepatobiliary(0.8%);10 endocrinological(1.2%).In particular,with regards to the involvement of the musculoskeletal system,arthritis Type 1 was found in 41 CD(19%)and in 61 UC(10.2%)(P=0.0012)and Type 2 in 25 CD(11.6%)and in 100 UC(16.8%)(P=0.0012).CONCLUSION:Mucocutaneous manifestations,arthritis Type 1 and uveitis were significantly more frequent in CD than UC.The complications of the musculoskeletal system were the mostly observed ones,often with symptoms more severe than intestinal ones,confirming the need for close cooperation with rheumatologists. | Maddalena Zippi Claudia Corrado Roberta Pica Eleonora Veronica Avallone Claudio Cassieri Daniela De Nitto Paolo Paoluzi Piero Vernia | 2014 | World Journal of Gastroenterology2014，20，46： | 10 |
| 2 | Hydrogen breath test for the diagnosis of lactose intolerance,is the routine sugar load the best one?显示文摘AIM: To evaluate the prevalence of lactose intolerance (LI) following a load of 12.5 g in patients diagnosed as high-grade malabsorbers using the hydrogen breath test (HBT)-25.METHODS: Ninety patients showing high-grade malabsorption at HBT-25 were submitted to a second HBT with a lactose load of 12.5 g.Peak hydrogen production,area under the curve of hydrogen excretion and occurrence of symptoms were recorded.RESULTS: Only 16 patients (17.77%) with positive HBT-25 proved positive at HBT-12.5.Hydrogen production was lower as compared to HBT-25 (peak value 21.55 parts per million (ppm) ± 29.54 SD vs 99.43 ppm ± 40.01 SD; P < 0.001).Symptoms were present in only 13 patients.The absence of symptoms during the high-dose test has a high negative predictive value (0.84) for a negative low-dose test.The presence of symptoms during the first test was not useful for predicting a positive low-dose test (positive predictive value 0.06-0.31).CONCLUSION: Most patients with a positive HBT-25 normally absorb a lower dose of lactose and a strict lactose restriction on the basis of a 'standard' HBT is,in most instances,unnecessary.Thus,the 25 g lactose tolerance test should probably be substituted by the 12.5 g test in the diagnosis of LI,and in providing dietary guidelines to patients with suspected lactose malabsorption/intolerance. | Fiorenza Argnani Mauro Di Camillo Vanessa Marinaro Tiziana Foglietta Veronica Avallone Carlo Cannella Piero Vernia | 2008 | World Journal of Gastroenterology2008，14，40： | 3 |
| 3 | Schwannoma of the rectum:A case report and literature review显示文摘Schwannoma is a tumor originating from the Schwann cells. Gastrointestinal schwannomas are uncommon stromal tumors of the intestinal tract and, in particular, rectal schwannomas are extremely rare. In fact, it is well established that schwannomas appear more frequently in the stomach and in the small intestine, while location in the colon or in the rectum is uncommon. Reading the literature, only few cases of rectal schwannoma have been reported. Their diagnosis is confirmed by the immunohisto chemical panel(S-100 protein). When these tumors are located in the colon and in the rectum, radical excision with wide margins is mandatory, due to their tendency to recur locally or become malignant, if left untreated. In the present study, we describe a case of a rectal schwannoma occured in a 72-year-old man, presented as a small polypoid lesion, which was successfully removed in toto by hot-biopsy, during the same endoscopy, due to the dimensons. No recurrence of the lesion was observed after 6 mo of follow-up. | Maddalena Zippi Roberta Pica Renzo Scialpi Claudio Cassieri Eleonora Veronica Avallone Giuseppe Occhigrossi | 2013 | World Journal of Clinical Cases2013，1，1： | 2 |
| 4 | Management of hepatic encephalopathy? role of rifaximin显示文摘 | Zeneroli ML Avallone R Corsi BL | 2005 | Chemotherapy2005，51，1： | 1 |
| 5 | Oxaliplatin plus dual in- hibition of thymidilate synthase duIing preoperative pelvic radio- therapy for locally advanced rectal carcinoma: long-term outcome 显示文摘 | Avallone A Delrio P Pecori B | 2011 | Int J Radiat Oncol Biol Phys2011，79，3： | 1 |
| 6 | Targeting thymidylate synthase in colorectal cancer:critical re-evaluation and emerging therapeutic role of raltitrexed显示文摘 | Avallone A Di Gennaro E Silvestro L | 2014 | Expert Opin Drug Saf2014，13，1： | 1 |
| 7 | A channel assignment algorithm for multiradio wireless mesh networks显示文摘 | Avallone S Akyildiz I F | 2008 | Computer Communications2008，31，： | 1 |
| 8 | In- volvement of pectolytic micro-organisms in coffee fermentation 显示文摘 | AVALLONE S BRTLLOUET J M eUYOT n | 2002 | International Journal of Food Science & Technology2002，37，2： | 1 |
| 9 | Oxaliplatin Plus Dual Inhibition of Thymidilate Synthase During Preoperative Pelvic Radiotherapy for Locally Advanced Rectal Carcinoma: Long-Term Outcome显示文摘 | Antonio Avallone Paolo Delrio Biagio Pecori Fabiana Tatangelo Antonella Petrillo Nigel Scott Pietro Marone Luigi Aloi Claudia Sandomenico Secondo Lastoria Vincenzo Rosario Iaffaioli Dario Scala Giovanni Iodice Alfredo Budillon Pasquale Comella | 2011 | International Journal of Radiation Oncology, Biology, Physics2011，，3： | 1 |
| 10 | Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells显示文摘 | AVALLONE A D I Gennaro E BRUZZESE F | 2007 | Anticancer Drugs2007，18，7： | 1 |
| 11 | A channel assignment algorithm for multi-radio wireless mesh networks 显示文摘 | Avallone S Akyildiz I F | 2008 | Computer Communications2008，31，： | 1 |
| 12 | A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway显示文摘 | Avallone R Demers A Rodrigue-Way A | 2006 | Mol Endocrinol2006，20，12： | 1 |
| 13 | Management of hepatic encephalopathy:role of rifaximin显示文摘 | Zeneroli ML Avallone R Corsi L | 2005 | Chemotherapy2005，51，1： | 1 |
| 14 | An energy efficient channel assignment and muting algorithm for multi - radio wireless mesh networks 显示文摘 | Avallone S | 2012 | Ad Hoe Networks2012，，10： | 1 |
| 15 | Fair Value or Cost Model? Drivers of Choice for IAS 40 in the Real Estate Industry 显示文摘 | QUAGLI A AVALLONE F | 2010 | European Accounting Review2010，19，3： | 1 |
| 16 | Maturational effects of single and multiple early-life seizures on AMPA receptors in prepubescent hippocampus 显示文摘 | Friedman LK Avallone JM Magrys B | 2007 | Dev Neurosci2007，29，： | 1 |
| 17 | Synthesis of potentially anti - inflammatory IPL576,092 - contignasterol and IPL576092 - manoalide hydrids 显示文摘 | IZZO I AVALLONE E MONICA C D | 2004 | Tetrahedron2004，60，： | 1 |
| 18 | Relationships of PAI-1 levels to central obesity and liver steatosis in a sample of adult male population in southern Italy显示文摘 | Antonio Barbato Roberto Iacone Giovanni Tarantino Ornella Russo Paolo Sorrentino Sonia Avallone Ferruccio Galletti Eduardo Farinaro Elisabetta Della Valle Pasquale Strazzullo | 2009 | Internal and Emergency Medicine2009，，4： | 1 |
| 19 | Behavioral characterisation of the flavonoids apigenin and chrysin显示文摘 | P Zanoli R Avallone M Baraldi | 2000 | Fitoterapia2000，，1： | 1 |
| 20 | Biweekly oxalipla- tin, raltitrexed, 5 - fluorouracil and folinic acid combination chem- otherapy during preoperative radiation therapy for locally advanced rectal cancer: a phase I - II study 显示文摘 | AVALLONE A DELRIO P GUIDA C | 2006 | Br J Cancer2006，94，12： | 1 |
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