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| 1 | Early radiological assessment of locally advanced pancreatic cancer treated with electrochemotherapy显示文摘AIM To report early imaging assessment of ablated area post electrochemotherapy(ECT) in patients with locally advanced pancreatic cancer(LAPC). METHODS ECT was performed in 19 LAPC patients enrolled in an approved ongoing clinical phase Ⅰ/Ⅱ study. Before and after ECT, 18 patients underwent computed tomography(CT) scan, 11 patients underwent morphological and functional magnetic resonance(MR) scan(dynamic contrast enhanced-MRI) calculating wash-in slope(WIS) and wash-out slope(WOS); diffusion weighted imaging calculating pseudo-diffusivity(Dp), perfusion fraction(fp) and tissue diffusivity(Dt); 10 patients underwentpositron emission tomography(PET). Response evaluation criteria in solid tumour(RECIST) on MR and CT were used to assess tumour therapy response. Choi on CT, PET response criteria in solid tumors(PERCIST) on PET and functional parameters on MR were used to evaluate treatment response.RESULTS For each patient no significant reduction was measurable by CT and MR using RECIST. According Choi criteria a partial response was obtained in 18/18(100.0%) patients. According PERCIST criteria 6/10(60.0%) patients showed a partial response, 3/10(30.0%) stable disease and 1/10(10.0%) progression disease. Moreover, using functional MR parameters, a significant reduction of viable tumour after ECT can be observed. According ΔWIS and ΔWOS 9/11(81.8%) patients exhibited a partial response and 2/11(18.2%) stable disease; 8/11(72.7%) patients were considered in partial response by ΔDp evaluation and 3/11(27.3%) in stable disease; according ΔDt 7/11(63.6%) patients showed a partial response, 1/11(9.1%) showed progression of disease and 3/11(27.3%) were stable. Perfusion fraction fp showed a significant reduction after ECT only in four patients. No significant difference was observed after ECT in signal intensity of T1-weighted images and T2-weighted images, and in equilibrium-phase of contrast study, according to χ2 test was observed. A good correlation was reported between ΔHounsfield unit and Δmaximum standardized uptake value and between Δfp and ΔWOS, with a significant statistically difference(P < 0.05) using Spearman correlation coefficient.CONCLUSION Perfusion and diffusion MR derived parameters, Choi, PERCIST criteria are more performant than morphological MR and CT criteria to assess ECT treatment response. | Vincenza Granata Roberta Fusco Sergio Venanzio Setola Mauro Piccirillo Maddalena Leongito Raffaele Palaia Francesco Granata Secondo Lastoria Francesco Izzo Antonella Petrillo | 2017 | World Journal of Gastroenterology2017,23,26: | 3 |
| 2 | Bone effect of adjuvant tamoxifen, letrozole or letrozole plus zoledronic acid in early-stage breast cancer: the randomized phase 3 HOBOE study 显示文摘 | Nuzzo F Gallo C Lastoria S | 2012 | Ann Oneol2012,23,8: | 1 |
| 3 | Orbital scintigraphy with -octreotide predicts the clinical response to corticosteroid therapy in patients with Graves' ophthalmopathy显示文摘 | Colao A Lastoria S Ferone D | 1998 | J Clin Endocrinol Metab1998,83,11: | 1 |
| 4 | Oxaliplatin Plus Dual Inhibition of Thymidilate Synthase During Preoperative Pelvic Radiotherapy for Locally Advanced Rectal Carcinoma: Long-Term Outcome显示文摘 | Antonio Avallone Paolo Delrio Biagio Pecori Fabiana Tatangelo Antonella Petrillo Nigel Scott Pietro Marone Luigi Aloi Claudia Sandomenico Secondo Lastoria Vincenzo Rosario Iaffaioli Dario Scala Giovanni Iodice Alfredo Budillon Pasquale Comella | 2011 | International Journal of Radiation Oncology, Biology, Physics2011,,3: | 1 |
| 5 | A sociodemographic, clini cal study of patients with venous ulcer显示文摘 | Abbade LP Lastoria S Rollo HD | 2005 | International Journal of Dermatology2005,44,12: | 1 |
| 6 | Scintimammography with ^99mTc-MDP in the detection of primary breast cancer显示文摘 | Piccolo S Lastoria S Muto P | 1997 | Q J Nucl Med1997,41,: | 1 |
| 7 | Characterization of Bacteriocin‐Coated Antimicrobial Polyethylene Films by Atomic Force Microscopy显示文摘 | A. LaStoria D.Ercolini F.Marinello G.Mauriello | 2008 | Journal of Food Science2008,,4: | 1 |
| 8 | Oxaliplatin Plus Dual Inhibition of Thymidilate Synthase During Preoperative Pelvic Radiotherapy for Locally Advanced Rectal Carcinoma: Long-Term Outcome显示文摘 | Antonio Avallone Paolo Delrio Biagio Pecori Fabiana Tatangelo Antonella Petrillo Nigel Scott Pietro Marone Luigi Aloi Claudia Sandomenico Secondo Lastoria Vincenzo Rosario Iaffaioli Dario Scala Giovanni Iodice Alfredo Budillon Pasquale Comella | 2011 | International Journal of Radiation Oncology Biology Physics2011,,3: | 1 |
| 9 | Technetium-99m-methylene diphosphonate scintimamography to image primary breast cancer 显示文摘 | Piccolo S Lastoria S Mainolfi C | 1995 | J NuclMed1995,36,5: | 1 |
| 10 | Successful Treatment of a Patient with Thymoma and Pure Red- Cell Aplasia with Octreotide and Prednisone 显示文摘 | Palmieri G Lastoria S Colao A | 1997 | The New England Journal of Medicine1997,336,: | 1 |
| 11 | The role of radiolabeled somatostatin analogs in adrenal imaging显示文摘 | Simone Maurea Secondo Lastoria Corradina Caracò Michele Klain Paola Varrella Wanda Acampa Pietro Muto Marco Salvatore | | Nuclear Medicine and Biology0,,: | 1 |
| 12 | A sociodemographic,clinic- ai study of patients with venous ulcer显示文摘 | Abbade LP Lastoria S Rollo HD | 2005 | International Journal of Dermatology2005,44,: | 1 |
| 13 | Prophylaxis of deep-vein thrombosis after lower extremity amputation:comparison of low molecular weight heparin with unfractionated heparin显示文摘 | LASTORIA S ROLLO H A YOSHIDA W B | 2006 | Acta Cir Bras2006,21,3: | 1 |
| 14 | The Diagnosis of Nonfunctioning Pheochromocytoma The Role of I-123 MIBG Imaging显示文摘 | SIMONE MAUREA SECONDO LASTORIA ALBERTO CUOCOLO LUIGI CELENTANO MARCO SALVATORE | | Clinical Nuclear Medicine0,,: | 1 |
| 15 | Technetium-99m-methylene diphosphonate scintimammography to image primary breast cancer显示文摘 | Sergio Piceoco Secondo Lastoria Ciro Mainolfi | 1995 | The journal of nudear medicine1995,36,5: | 1 |
| 16 | Scintimammography with technetium-99m methoxyisobutylisonitrile: results of a prospective European multicentre trial显示文摘 | Palmedo H Biersack H J Lastoria S | 1998 | Eur J Nucl Med1998,25,: | 1 |
| 17 | Dose-dense(dd) ABVD and dose-dense/dose-intense (dd-di) ABVD in newly diagnosed patients (pts), intermediate- and advanced-stage with classical Hodgkin' s lym- phoma ( cHL ) : final results 显示文摘 | Russo F Corazzelli G Lastoria S | 2009 | Blood2009,114,22: | 1 |
| 18 | Clinical implication of somatostatin receptor scintigraphy in ophthalmic Graves'disease显示文摘 | Colao A Pivonello R Lastoria S | 2000 | Eur J Endocrinol2000,143,1: | 1 |
| 19 | Technetium-99m-methyl- ene diphosphonate scintimammography to image primary breast cancer 显示文摘 | Piccolo S Lastoria S Mainolfi C | 1995 | Nacl Med1995,36,5: | 1 |
| 20 | Accuracy of endoscopic ultrasound in staging and restaging patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation显示文摘 | Pietro Marone Mario de Bellis Antonio Avallone Paolo Delrio Giovanni di Nardo Valentina D’Angelo Fabiana Tatangelo Biagio Pecori Elena Di Girolamo Vincenzo Iaffaioli Secondo Lastoria Giovanni Battista Rossi | 2011 | Clinics and Research in Hepatology and Gastroenterology2011,,10: | 1 |