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| 1 | Improved bowel preparation increases polyp detection and unmasks significant polyp miss rate显示文摘AIM: To retrospectively compare previous-day vs splitdose preparation in terms of bowel cleanliness and polyp detection in patients referred for polypectomy. METHODS: Fifty patients underwent two colonoscopies: one diagnostic in a private clinic and a second for polypectomy in a University Hospital. The latter procedures were performed within 12 wk of the index ones. Examinations were accomplished by two experienced endoscopists, different in each facility. Twenty-seven patients underwent screening/surveillance colonoscopy, while the rest were symptomatic. Previous day bowel preparation was utilized initially and splitdose for polypectomy. Colon cleansing was evaluated using the Aronchick scale. We measured the number of detected polyps, and the polyp miss rates per-polyp.RESULTS: Excellent/good preparation was reported in 38 cases with previous-day preparation(76%) vs 46 with split-dose(92%), respectively(P = 0.03). One hundred and twenty-six polyps were detected initially and 169 subsequently(P < 0.0001); 88 vs 126 polyps were diminutive(P < 0.0001), 25 vs 29 small(P = 0.048) and 13 vs 14 equal or larger than 10 mm. The miss rates for total, diminutive, small and large polyps were 25.4%, 30.1%, 13.7% and 6.6%, respectively. Multivariate analysis revealed that split-dose preparation was significantly associated(OR, P) with increased number of polyps detected overall(0.869, P < 0.001), in the right(0.418, P = 0.008) and in the left colon(0.452, P = 0.02). CONCLUSION: Split-dose preparation improved colon cleansing, enhanced polyp detection and unmasked significant polyp miss rates. | Ioannis S Papanikolaou Athanasios D Sioulas Nektarios Magdalinos Iosif Beintaris Lazaros-Dimitrios Lazaridis Dimitrios Polymeros Chrysoula Malli George D Dimitriadis Konstantinos Triantafyllou | 2015 | World Journal of Clinical Cases2015，3，10： | 4 |
| 2 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 3 | Effects of chromium (VI) addition on the activated sludge process显示文摘 | Athanasios S Stasinakis Nikolaos S Thomaidis Daniel Mamais Evangelia C Papanikolaou Angeliki Tsakon Themistokles D Lekkas | 2002 | Water Research2002，，9： | 2 |
| 4 | Adipokines in Nonalcoholic Steatohepatitis: From Pathogenesis to Implications in Diagnosis and Therapy显示文摘 | Emmanuel A. Tsochatzis George V. Papatheodoridis Athanasios J. Archimandritis Fulvio D’Acquisto | 2009 | Mediators of Inflammation2009，，： | 2 |
| 5 | Muscle wasting in rheumatoid arthritis:The role of oxidative stress显示文摘Rheumatoid arthritis(RA), the commonest inflammatory arthritis, is a debilitating disease leading to functional and social disability. In addition to the joints, RA affects several other tissues of the body including the muscle. RA patients have significantly less muscle mass compared to the general population. Several theories have been proposed to explain this. High grade inflammation, a central component in the pathophysiology of the disease, has long been proposed as the key driver of muscle wasting. More recent findings however, indicate that inflammation on its own cannot fully explain the high prevalence of muscle wasting in RA. Thus, thecontribution of other potential confounders, such as nutrition and physical activity, has also been studied. Results indicate that they play a significant role in muscle wasting in RA, but again neither of these factors seems to be able to fully explain the condition. Oxidative stress is one of the major mechanisms thought to contribute to the development and progression of RA but its potential contribution to muscle wasting in these patients has received limited attention. Oxidative stress has been shown to promote muscle wasting in healthy populations and people with several chronic conditions. Moreover, all of the aforementioned potential contributors to muscle wasting in RA(i.e., inflammation, nutrition, and physical activity) may promote pro- or antioxidative mechanisms. This review aims to highlight the importance of oxidative stress as a driving mechanism for muscle wasting in RA and discusses potential interventions that may promote muscle regeneration via reduction in oxidative stress. | Antonios Stavropoulos-Kalinoglou Charikleia Deli George D Kitas Athanasios Z Jamurtas | 2014 | World Journal of Rheumatology2014，4，3： | 2 |
| 6 | Prospective evaluation of the short access cholangioscopy for stone clearance and evaluation of indeterminate strictures显示文摘BACKGROUND: Peroral cholangioscopy facilitates diagnosis and therapy of biliary disorders. This study prospectively evaluated a new short access cholangioscopy. METHODS: Consecutive patients were included as follows: difficult stones(group 1) underwent cholangioscopy with electrohydraulic lithotripsy and indeterminate biliary strictures(group 2) were evaluated with macroscopic assessment and cholangioscopy guided biopsy sampling. We evaluated the complete stone clearance rate(group 1) and diagnostic accuracy(group 2). Follow-up was performed over a median of 13 and 16 months, respectively.RESULTS: Group 1(n=21): complete stone clearance defined as lack of stones in cholangiography and stone removal during cholangioscopy was achieved in 15(71.4%) patients. Clinical stone clearance defined as lack of symptoms, laboratory abnormalities and hospital visits during follow-up, irrespective of stone clearance was evident in 17(81.0%) patients. One serious adverse event occurred(bile duct perforation). Group 2(n=28): malignancy was confirmed in 15 patients. Sensitivity, specificity and diagnostic accuracy of cholangioscopy were 85.7%, 75.0% and 80.7%, respectively. Sensitivity, specificity and diagnostic accuracy of biopsies were 54.5%, 100.0% and 72.2%, respectively. No serious adverse events occurred, and one patient was lost to follow-up.CONCLUSIONS: The novel system enabled complex stone treatment and biliary stricture diagnosis. Cholangioscopy outperformed direct biopsy regarding characterization of indeterminate strictures. | Athanasios D Sioulas Muhammad A El-Masry Stefan Groth Guido Schachschal Mario Anders Thomas Rosch Ulrike Denzer | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，1： | 2 |
| 7 | Genome sequence and analysis of the soil cellulolytic actinomyeete Thermobifidafusca YX 显示文摘 | Athanasios L Konstantinos M Natalia I lain A Miriam L Genevieve D Michele M Alia L Susan L Alex C Paul R David BW Nikos K | 2007 | J Bacteriol2007，189，6： | 1 |
| 8 | Speciation of chromium in wastewater and sludge by extraction with liquid anion exchanger Amberlite LA-2 and electrothermal atomic absorption spectrometry显示文摘 | Athanasios S Stasinakis Nikolaos S Thomaidis Themistokles D Lekkas | 2002 | Analytica Chimica Acta2002，，1： | 1 |
| 9 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (alliurn sativum) 显示文摘 | Athanasios C Nikolas G S Dimitra J D | 2006 | Ultrasonics Sonochemistry2006，13，1： | 1 |
| 10 | Dynamic Power Allocation for Broadband Multi-Beam Satellite Communication Networks 显示文摘 | Apostolos Destounis Athanasios D Panagopoulos | 2011 | IEEE Communications Letters (S1089-7798)2011，15，4： | 1 |
| 11 | Selection combining site diversity performance in high altitude platform networks显示文摘 | ATHANASIOS D PANAGOPOULOS EVANGELIA M | 2007 | IEEE Communications Letters2007，11，10： | 1 |
| 12 | A validated high-performance liquid chromatographic method for the determination of glibenclamide in human plasma and its application to pharmacokinetic studies显示文摘 | IOANNIS N ATHANASIOS C D | 2002 | Pharm Biomed Anal2002，28，： | 1 |
| 13 | Results using the AO hook plate for dislocation of the acromioclavicular joint显示文摘 | Athanasios K Andreas M Constantinos D | 2008 | Expert Rev Med Device2008，5，5： | 1 |
| 14 | Effects of chromium (VI) addition on the activated sludge process显示文摘 | Athanasios S Stasinakis Nikolaos S Thomaidis Daniel Mamais Evangelia C Papanikolaou Angeliki Tsakon Themistokles D Lekkas | 2002 | Water Research2002，，9： | 1 |
| 15 | Layered Organosilicate Nanoparticles with Liquid-Like Behavior 显示文摘 | Athanasios B Bourlinos Subhendu Ray Chowdhury David D Jiang | 2005 | Small2005，1，1： | 1 |
| 16 | Evaluation of the turbulence models for the simulation of the flow over a national advisory committee for aeronautics(NACA)0012 airfoil显示文摘 | Eleni D C Athanasios T I Dionissios M P | 2012 | Journal of Mechanical Engineering Research2012，4，3： | 1 |
| 17 | A UTD Propagation Model in Urban Microcellular En- vironments显示文摘 | Athanasios G K Ioannis D K George B K | 1997 | IEEE Transactions on Vehicular Technology1997，46，1： | 1 |
| 18 | Adipokines in Nonalcoholic Steatohepatitis: From Pathogenesis to Implications in Diagnosis and Therapy显示文摘 | Emmanuel A. Tsochatzis George V. Papatheodoridis Athanasios J. Archimandritis Fulvio D'Acquisto | 2009 | Mediators of Inflammation2009，，： | 1 |
| 19 | Non-steroidal antiinflammatory drug-copper(11) complexes: structure and biological perspectives显示文摘 | FILITSA D STELLA F ATHANASIOS N | 2011 | Dalton Trans2011，40，： | 1 |
| 20 | Effect of protein kinase inhibitors on the stretch-elicited c-Fos and c-Jun up-regulation in human PDL osteoblast-like cells显示文摘 | Kletsas D B Efthimia K Athanasios G | 2002 | J Cell Physiol2002，190，3： | 1 |
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