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| 1 | Current surgical management of pancreatic endocrine tumor liver metastases显示文摘BACKGROUND: The management of metastatic disease in pancreatic endocrine tumors (PETs) demands a multidisciplinary approach and the cooperation of several medical specialties. The role of surgery is critical, even when a radical excision cannot always be achieved. DATA SOURCES: A PubMed search of relevant articles published up to February 2011 was performed to identify current information about PET liver metastases regarding diagnosis and management, with an emphasis on surgery. RESULTS: The early diagnosis of metastases and their accurate localization, most commonly in the liver, is very important. Surgical options include radical excision, and palliative excision to relieve symptoms in case of failure of medical treatment. The goal of the radical excision is to remove the primary tumor bulk and all liver metastases at the same time, but unfortunately it is not feasible in most cases. Palliative excisions include aggressive tumor debulking surgeries in well-differentiated carcinomas, trying to remove at least 90% of the tumor mass, combined with other additional destructive techniques such as hepatic artery embolization or chemoembolization to treat metastases or chemoembolization to relieve symptoms in cases of rapidly growing tumors. The combination of chemoembolization and systemic chemotherapy results in better response and survival rates. Other local destructive techniques include ethanol injection, cryotherapy and radiofrequency ablation. CONCLUSION: It seems that the current management of PETs can achieve important improvements, even in advanced cases. | Theodoros E Pavlidis Kyriakos Psarras Nikolaos G Symeonidis Efstathios T Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 5 |
| 2 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 3 | A novel ga- lacto-oligosaccharide mixture increases the bifidobacterial population number in a continuous in vitro fermentation sys- tem and in the proximal colonic contents of pigs in vivo 显示文摘 | George T Athanasios K G Jennifer M G el al | 2005 | The American Society for :utritional Sciencese2005，135，7： | 1 |
| 4 | Influential factors of an Educational Programme Implementation Evaluation: A crossvalidation approach显示文摘 | Vasilios G Nikolaos T Athanasios K | 2007 | Evaluation and Research in Education2007，，10： | 1 |
| 5 | Exposure to major volatile organic compounds and carbonyls in European indoor environments and associated health risk 显示文摘 | DIMOSTHENIS A S SPYROS P K ALBERTO G IOANNIS L L ATHANASIOS K | 2011 | Environment International2011，37，4： | 1 |
| 6 | Evolution of aggregate size and fractal dimension during Brownian coagulation显示文摘 | Margaritis K Athanasios G K | 2001 | J Aerosol Sci2001，32，： | 1 |
| 7 | A UTD Propagation Model in Urban Microcellular En- vironments显示文摘 | Athanasios G K Ioannis D K George B K | 1997 | IEEE Transactions on Vehicular Technology1997，46，1： | 1 |
| 8 | The quality of e-services: measuring satisfaction of Internet customers: operational research 显示文摘 | Panagiotis K Athanasios S Evangelos G | 2007 | International Journal2007，7，2： | 1 |
| 9 | Effective survival of immobilized Lactobacillus casei during ripening and heat treatment of probiotic dry-fermented sausages and investigation of the microbial dynamics显示文摘 | Marianthi S Athanasios K Alex G | 2014 | Meat Science2014，，96： | 1 |
| 10 | Distribu- tion of Persistent Organic Pollutants, Polycyclic Aro- matic Hydro-Carbons and Trace Elements in Soil and Vegetation Following a Large Scale Landfill Fire in Northern Greece显示文摘 | Loukia C Panagiofis G Athanasios K | 2008 | Environ Pollut2008，34，2： | 1 |
| 11 | Diuron biodegradation in activated sludge batch reactors under aerobic and anoxic conditions 显示文摘 | ATHANASIOS S S SEVASTI K GEORGIA G | 2009 | Water Research2009，，43： | 1 |
| 12 | Purification of oligosaccharides by nanofiltration显示文摘 | Athanasios K G Petros G K Haydn R S | 2002 | J Membr Sci2002，209，1： | 1 |
| 13 | Effect of protein kinase inhibitors on the stretch-elicited c-Fos and c-Jun up-regulation in human PDL osteoblast-like cells显示文摘 | Kletsas D B Efthimia K Athanasios G | 2002 | J Cell Physiol2002，190，3： | 1 |
| 14 | The use of a harmonic scalpel in thyroid surgery:a reportof a 3-year experience显示文摘 | Konstantinos K Athanasios S K Panagiotis G D | 2007 | Am J Surg2007，193，6： | 1 |
| 15 | Prediction ofGreek takeover targets via bootstrapping on mixed Logitmodel 显示文摘 | Athanasios T evangelos K Antonios G | 2012 | Review of Accounting and Finance2012，11，3： | 1 |
| 16 | Purification of oligosaccharides by nanofiltration显示文摘 | Athanasios K G Petros G K Haydn R S | 2002 | J Membr Sci2002，209，1： | 1 |
| 17 | Fractionation of oligosaecharides by nanofiltration 显示文摘 | Athanasios K G Alistair S G Robert A R | 2003 | Journal of the Science of Food and Agriculture2003，83，： | 1 |
| 18 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from gar lic (Allium sativum ) 显示文摘 | Athanasios C K Nikolaos G S Dimitra J D | 2006 | Ultrasonics Sonochemistry2006，13，： | 1 |
| 19 | Diuron biodegra-dation in activated sludge batch reactors under aerobic and anoxic conditions显示文摘 | Athanasios S S Sevasti K Georgia G | 2009 | Water Research2009，43，5： | 1 |
| 20 | Early intervention for relapse in schizophrenia: impact of cognitive behavioural therapy on negative beliefs about psychosis and self-esteem 显示文摘 | Andrew G Athanasios K Kevin P | 2006 | Br J Clin Psychol2006，45，： | 1 |
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