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| 1 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 2 | 临床试验数据共享声明国际医学期刊编辑委员会统一要求显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了1项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。迄今,应我们的反馈要求,ICMJE收到了很多来自个人和团体的意见。 | Darren B Taichman Peush Sahni Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Deutsches Arzteblatt Joyce Backus 季媛媛 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 3 | Effect of Surface Oxidation of the Support on the Thiophene Hydrodesulfurization Activity of Mo, Ni, and NiMo Catalysts Supported on Activated Carbon显示文摘 | CALAFAT A LAINE J | 1996 | Journal of Catalysis1996，162，： | 2 |
| 4 | 临床试验数据共享声明显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了一项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。 | Darren B Taichman Peush Sahni Anja Pinborg Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Joyce Backus 季媛媛 | 2017 | 中国医院院长2017，13，16： | 2 |
| 5 | CTGF expression is induced by TGF-beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis 显示文摘 | Chen MM Lain A Abraham JA | 2000 | J Mol Cell Cardiol2000，32，10： | 1 |
| 6 | Genome sequence and analysis of the soil cellulolytic actinomyeete Thermobifidafusca YX 显示文摘 | Athanasios L Konstantinos M Natalia I lain A Miriam L Genevieve D Michele M Alia L Susan L Alex C Paul R David BW Nikos K | 2007 | J Bacteriol2007，189，6： | 1 |
| 7 | Contrast enhancement by multi-scale adaptive histogram equalization显示文摘 | Jin Yingpeng Fayad L Laine A | 2001 | SPIE proceedings series2001，4478，1： | 1 |
| 8 | Comparison of polyethylene glycol with and without electrolytes in the treatment of constipation in elderly institutionalized patients:a randomized,double-blind,parallel-group study显示文摘 | Seinel(a) L Sairanen U Laine T | 2009 | Drugs Aging2009，26，8： | 1 |
| 9 | Texture classification by wavelet packet signatures显示文摘 | Laine A Fan J | 1993 | IEEE Trans Pattern Recognit Machine Intell (S0162-8828)1993，，15： | 1 |
| 10 | Sindbis viruses and other alphaviruses as cause of human arthritic disease显示文摘 | Laine M Luukkainen R Toivanen A | 2004 | J Intern Med2004，256，6： | 1 |
| 11 | Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis显示文摘 | BOMBARDIER C LAINE L REICIN A | 2000 | N Engl J Med2000，343，21： | 1 |
| 12 | Proteolytic activity of the plun poxpotyvirus NIa-like protein in Escherichia coli 显示文摘 | Garcia J A Riechmann J L Lain S | 1989 | Virology1989，170，： | 1 |
| 13 | Electroencephalographic findings during experimental human exposure to m-xylene显示文摘 | Seppalainen A M Laine A salmi T B | 1991 | Arch Environ Health1991，46，1： | 1 |
| 14 | On Pareto Improving Commodity Tax Changes under Fiscal Competition显示文摘 | A lain de Crombrugghe Henry Tulkens | 1990 | Journal of Public Economics1990，，41： | 1 |
| 15 | Microwave pyrolysis, a novel process for recycling waste automotive engine oil 显示文摘 | Lain S S Russell A D Chaseh A | 2010 | Energy2010，35，7： | 1 |
| 16 | Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis显示文摘 | Bombardier C Laine L Reicin A Shapiro D | 2000 | N Engl J Med2000，343，16： | 1 |
| 17 | Estimation of fetal shoulder width by measurement of the humerospinous distance by ultrasound 显示文摘 | Riska A Laine H Voutilainen P | 1996 | Ultrasound in obstetrics & gynecology: the official journal of the International Society of Ultrasound in Obstetrics and Gynecology1996，7，： | 1 |
| 18 | Texture classification by wavelet packet signatures显示文摘 | Laine A Fan J | 1993 | IEEE Trans on Pattern Analysis and Machine Intelligence1993，15，： | 1 |
| 19 | Semantic processing without conscious understanding in a global aphasic: evidence from auditory event-related brain potentials显示文摘 | Cevonsuo A Laine M | 1996 | Cortex1996，32，1： | 1 |
| 20 | Wastewater recycling the potential for membrane bio - reactors 显示文摘 | B Jefferson A Laine | 1997 | Water Quality International1997，，1112： | 1 |
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