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126篇 您的检索式:作者名="AMES T B"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
2左心质量与脑磁共振成像和认知功能的关系显示文摘左心室质量(1eft ventricularmass,LVM)被证实可以作为长期暴露于数个危险因素下时造成的靶器官损害的评估标准。有关中年LVM和晚期认知表现之间联系的资料很少。纳入StrongHeart研究(SHS,1993—1995)及其附属的CDCAI(脑血管病及其对美国印第安人的影响)研究(2010—2013)中721名成年研究对象(平均基础年龄56岁),这些人群心血管病风险较高。黄洁 叶鹏 Haring B Omidpanah A Suchy Dicey AM Best LG Verney SP Shibata DK Cole SA Ali T Howard BV Buchwald D Devereux RB 2017中华高血压杂志2017,25,10:4
3Morphological and functional changes in cardiac myocytes isolated from mice overexpressing TNF-alpha 显示文摘Janczewski AM Kadokami T Lemster B 2003Am J Physiol Heart Circ Physiol2003,284,3:1
4Anticancer, antichemotactic and antimicrobial activities of marine sponges collected off the coast of Santa Catarina, southern Brazil显示文摘Noel R Monks Clea Lerner Amélia T Henriques Fabiane M Farias Elfrides E.S Schapoval Edna S Suyenaga Adriana B da Rocha Gilberto Schwartsmann Beatriz Mothes 2002Journal of Experimental Marine Biology and Ecology2002,,1:1
5Oxidants, antioxidants, and the degeneration disease of the aging显示文摘Ames B N Shigenaga M K Hagen T M 1993Pro Natl Acad Sci USA1993,90,:1
6Oxidative damage and mitochondrial decay in aging显示文摘Shigenaga M K Hagen T M Ames B N 1994Proc Nat Acad Sci USA1994,91,10:1
7Studies on thermostable antigens, production of species-specific antiadrenal sera and comparison of immunological techniques in meat speciation显示文摘Sherikar A T Karkare U D Khot J B et am 1993Meat Sci1993,33,1:1
8Gas phase oxidants of cite smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma : Protective effects of ascorbic acid 显示文摘FREI B FOR7I'E T M AMES B N 1991Biochem J1991,277,:1
9Does Tumor Size Influence the Outcome of Laparoscopic Adnrenalectomy显示文摘Kazaryan AM Mala T Edwin B 2001J Lap Surg Tech2001,11,1:1
10Oxidants, antioxidants, and the degenerative diseases of aging 显示文摘Ames B N Shigenaga M K Hagen T M 1993Proc Natl Acad Sci USA1993,90,17:1
11D esign and perform ance of a 215 GHz pulsed radar system 显示文摘R obert E M cln T osh J am es B M ead 1988IEEE Transactions onMicrowave Theory and T e c h n ic s1988,36,6:1
12Metabolic endotoxemia initiates obesity and insulin resistance 显示文摘Cani PD Amar J Iglesias MA Poggi M Knauf C Bastelica D Neyrinck AM Fava F Tuohy KM Chabo C Waget A Delm6e E Cousin B Sulpice T Chamontin B Ferrieres J Tanti JF Gibson OR Casteilla L Delzenne NM Alessi MC Burcelin R 2007Diabetes2007,56,7:1
13Adequacy of surgeonperformedultrasound-guided thyroid fine-needle as-piration biopsy显示文摘Bhatki AM Brewer B Robinson-Smith T 2008Otolaryngol Head NeckSurg2008,139,1:1
14Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘Heimann T van Ginneken B Styner MA Arzhaeva Y Aurich V Bauer C Beck A Becket C Beichel R Bekes G Bello F Binnig G Bischof H Bornik A Cashman PM Chi Y Cordova A Dawant BM Fidrich M Furst JD Furukawa D Grenacher L Hornegger J Kainmuller D Kitney RI Kobatake H Lamecker H Lange T Lee J Lennon B Li R Li S Meinzer HP Nemeth G Raicu DS Rau AM van Rikxoort EM Rousson M Rusko L Saddi KA Schmidt G Seghers D Shimizu A Slagmolen P Sorantin E Soza G Susomboon R Waite JM Wimmer A Wolf I 2009IEEE Transactions on Medical Imaging2009,28,8:1
15Oxidants,Antioxidants and the Degenerative Diseases of Aging显示文摘Ames B N Shigenaga M K Hagen T M 1993Proc Natl Acad Sci USA1993,90,:1
16Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma:Protective effects of ascorbic acid显示文摘FREI B FORTE T M AMES B N 1991Biochem J1991,277,:1
17Antibodies to flagellin indicate reactivity to bacterial antigens in IBS pa- tients显示文摘Schoepfer AM Schaffer T Seibold-Schmid B 2008NeurogastroenterolMotil2008,20,10:1
18Bio- mechanical comparision of Posterior lumbar interbody fu- sion and transforaminal lumbar interbody fusion performed at 1 and 2 levels显示文摘CHRISTOPHER P AMES T B FRANK L 2005Spine2005,30,19:1
19Oxidative damage and mitochondrial decay in aging显示文摘SHIGENAGE M K HAGEN T M AMES B N 1994Proc Natl Acad Sci USA1994,91,10:1
20Mitochondrial decay in aging显示文摘Ames B N Shigenaga M K Hagen T M 1995Biochem Biophys Acta1995,1271,1:1
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