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| 1 | Current concepts on osteonecrosis of the femoral head显示文摘It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the United States. Thelack of level 1 evidence in the literature makes it difficult to identify optimal treatment protocols to manage patients with pre-collapse avascular necrosis of the femoral head, and early intervention prior to collapse is critical to successful outcomes in joint preserving procedures. There have been a variety of traumatic and atraumatic factors that have been identified as risk factors for osteonecrosis, but the etiology and pathogenesis still remains unclear. Current osteonecrosis diagnosis is dependent upon plain anteroposterior and frog-leg lateral radiographs of the hip, followed by magnetic resonance imaging(MRI). Generally, the first radiographic changes seen by radiograph will be cystic and sclerotic changes in the femoral head. Although the diagnosis may be made by radiograph, plain radiographs are generally insufficient for early diagnosis, therefore MRI is considered the most accurate benchmark. Treatment options include pharmacologic agents such as bisphosphonates and statins, biophysical treatments, as well as joint-preserving and joint-replacing surgeries. the surgical treatment of osteonecrosis of the femoral head can be divided into two major branches: femoral head sparing procedures(FHSP) and femoral head replacement procedures(FHRP). In general, FHSP are indicated at pre-collapse stages with minimal symptoms whereas FHRP are preferred at post-collapse symptomatic stages. It is difficult to know whether any treatment modality changes the natural history of core decompression since the true natural history of core decompression has not been delineated. | Joaquin Moya-Angeler Arianna L Gianakos Jordan C Villa Amelia Ni Joseph M Lane | 2015 | World Journal of Orthopedics2015，6，8： | 94 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Effect of menstrual cycle and hormonal treatment on ki-67 and bcl-2 expression and adenomyosis 显示文摘 | Hugo MJ Amelia M Eduardo S | 2005 | Gynecol Endocrinol2005，20，： | 1 |
| 4 | Croce miR-15 and miR-16 induce apoptosisby targeting BCL2显示文摘 | Amelia C Carlo M | 2005 | PNAS2005，39，13： | 1 |
| 5 | Zeolite as efficient catalysts for key transformations in carbohydrate chemistry 显示文摘 | Xavier Nuno M Lucas Susana D Rauter Amelia P | 2009 | Journal of Molecular Catalysis A: Chemical2009，305，12： | 1 |
| 6 | Inducible cAMP early repressor,an endogenous antagonist of cAMP responsive element-binding protein,evokes neuronal apoptosis in vitro显示文摘 | Jacek J Barbara M Amelia S | 2003 | J Neurosei2003，23，11： | 1 |
| 7 | Mesenchymal stem cells surpress lymphocyte proliferation in vitro and prolong skin graft survival in vivo显示文摘 | Amelia B Cord S Siatskas M | 2002 | Experimental Hematology2002，30，： | 1 |
| 8 | Bulk and interfacial viscoelasticity in concentrated emul-sions: the role of the surfactant显示文摘 | MIGUEL W P AMELIA T G ANTONIO M R | 2011 | Food Hydrocol-loids2011，25，： | 1 |
| 9 | Soil erosion under different vegetation covers in the Venezuelan Andes显示文摘 | Amelia L Ataroff M Robert O | 2002 | The Environmentalist2002，，2： | 1 |
| 10 | Recovery of CdS nanoerystal defects through conjugation with proteins 显示文摘 | AMELIA M FLAMINI R LATI'ERINI L | 2010 | Langmuir2010，26，10： | 1 |
| 11 | Activated carbon fibers from Nomex by chemical activation with phosphoric acid 显示文摘 | FABIAN SUAREZ-GARCIA AMELIA M ARTINEZ-ALONSO JUAN M D | 2004 | Carbon2004，42，： | 1 |
| 12 | Enhancement of anaer- obicdigestion of sisal leaf decortication residues bybiological pre- treatment显示文摘 | Muthangya M M Anthony M K Amelia K | 2009 | Journal of Agricuhuraland Biological Science2009，4，4： | 1 |
| 13 | Rauter sugars containing α,β-unsaturated carbonyl systems:synthesis and their usefulness as scaffolds in carbohydrate chemistry显示文摘 | NUNO M XAVIER AMELIA P | 2008 | Carbohydr Res2008，343，： | 1 |
| 14 | Emerging roles for multipotent,bone marrow-derived stromal cells in host defense显示文摘 | Auletta Jeffery J Deans Robert J Bartholomew Amelia M | | 0，，08： | 1 |
| 15 | Dimorphism in Candida albicans: contribution of mannoproteins to the architecture of yeast and mycelial cell wails显示文摘 | Elorza M V Amelia M Rafael S | 1985 | Journal of General Microbiology1985，131，2： | 1 |
| 16 | Nicotinic acetylcholine receptor alpha 7 subunit is an essential regulator of inflammation 显示文摘 | Wang H Yu M Oehani M Amelia CA Tanovic M Susada S | 2003 | Nature2003，421，6921： | 1 |
| 17 | Neonatal Hear-ing Screening : Failures, hearing loss and risk indicators显示文摘 | Raquel M O Marisa F A Amelia M N | 2011 | Braz J Otorhinolaryngol2011，，6： | 1 |
| 18 | Two Contrasting Severe Seasonal Extremes in Tropical South America in 2012: Flood in Amazonia and Drought in Northeast Brazil显示文摘 | Marengo Jose A Alves Lincoln M Soares Wagner R Rodriguez Daniel A Camargo Helio Riveros Marco Paredes Pabl? Amelia Diaz | 2013 | Journal of Climate2013，，22： | 1 |
| 19 | Mathematical modeling of the heat and mass transfer in a stationary potato sphere impinged by a single round liquid jet in a hydro fluidization system显示文摘 | Juan M Peralta Amelia C Rubiolo Susana E Zorrilla | 2012 | Journal of Food Engineering2012，109，3： | 1 |
| 20 | Modification of the Surface Properties of an Activated Carbon by Oxygen Plasma Treatment 显示文摘 | Garcia A B Amelia M A | 1998 | Fuel1998，6，： | 1 |
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