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| 1 | Liver metastases:Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance显示文摘The development of ultrasound contrast agents with excellent tolerance and safety profiles has notably improved liver evaluation with ultrasound(US)for several applications,especially for the detection of metastases.In particular,contrast enhanced ultrasonography(CEUS)allows the display of the parenchymal microvasculature,enabling the study and visualization of the enhancement patterns of liver lesions in real time and in a continuous manner in all vascular phases,which is similar to contrast-enhanced computed tomography(CT)and contrast-enhanced magnetic resonance imaging.Clinical studies have reported that the use of a contrast agent enables the visualization of more metastases with significantly improved sensitivity and specificity compared to baseline-US.Furthermore,studies have shown that CEUS yields sensitivities comparable to CT.In this review,we describe the state of the art of CEUS for detecting colorectal liver metastases,the imaging features,the literature reports of metastases in CEUS as well as its technique,its clinical role and its potential applications.Additionally,the updated international consensus panel guidelines are reported in this review with the inherent limitations of this technique and best practice experiences. | Vito Cantisani Hektor Grazhdani Cristina Fioravanti Maria Rosignuolo Fabrizio Calliada Daniela Messineo Maria Giulia Bernieri Adriano Redler Carlo Catalano Ferdinando D’Ambrosio | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 2 | Application of Trichoderma harzianum (T22) and Trichoderma atroviride (P1) as plant growth promoters, and their compatibility with copper oxychloride显示文摘Trichoderma strains are used in agriculture because they provide to the plants the following benefits: i) are rhizosphere competence and establish stable rhizosphere microbial communities; ii) control plant disease caused by pathogenic and competitive microflora, by using a variety of mechanisms; iii) improve vegetative growth, root development and yield; iv) make nutrients more available to the plant. In this work we have investigated the ability of T. harzianum T22 and T. atroviride P1 to improve plant growth of locally important horticultural crops: lettuce, tomatoes and peppers and to prevent disease in the greenhouse and field. The effect of the Trichoderma treatment was evaluated by determining the weight of fresh and dry roots and above ground plant biomass, measuring plants height, counting the number of emerged leaves (lettuce, tomatoes and peppers) and quantifying production (tomatoes and peppers). No disease symptoms were found during production, although Fusarium sp. strains pathogenic to tomato were detected in the soil. Compounds containing copper oxychloride are frequently used for fungal disease control in agriculture. In order to investigate the compatibility of T. harzianum T22 and T. atroviride P1 with copper oxychloride applications, the effect on mycelia growth was monitored in both liquid and solid medium. In general, the tests indicated a high level of tolerance of the Trichoderma strains to concentrations of copper oxychloride varying from 0.1 to 5 mmol/L. | Francesco Vinale Gaetano D'Ambrosio Khalid Abadi Felice Scala Roberta Marra David Turrà Sheridan L Woo Matteo Lorito | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 7 |
| 3 | Comparison of four proton pump inhibitors for the short-term treatment of esophagitis in elderly patients显示文摘AIM: To compare efficacy and tolerability of four proton pump inhibitors (PPIs) commonly used in the short-term therapy of esophagitis in elderly patients.METHODS: A total of 320 patients over 65 years with endoscopically diagnosed esophagitis were randomly assigned to one of the following treatments for 8 wk: (1) omeprazole 20 mg/d; (2) lansoprazole 30 mg/d; (3) pantoprazole 40 mg/d, or (4) rabeprazole 20 mg/d. Major symptoms, compliance, and adverse events were recorded. After 8 wk, endoscopy and clinical evaluation were repeated.RESULTS: Per protocol and intention to treat healing rates of esophagitis were: omeprazole = 81.0% and 75.0%, lansoprazole = 90.7% (P = 0.143 vs omeprazole) and 85.0%, pantoprazole = 93.5% (P = 0.04 vs omeprazole) and 90.0% (P = 0.02 vs omeprazole), rabeprazole = 94.6% (P = 0.02 vs omeprazole) and 88.8% (P = 0.04 vs omeprazole). Dividing patients according to the grades of esophagitis, omeprazole was significantly less effective than the three other PPIs in healing grade 1 esophagitis (healing rates: 81.8% vs 100%, 100% and 100%, respectively, P = 0.012). Pantoprazole and rabeprazole (100%) were more effective vs omeprazole (89.6%, P = 0.0001)and lansoprazole (82.4%, P = 0.0001) in decreasing heartburn. Pantoprazole and rabeprazole (92.2% and 90.1%, respectively) were also more effective vs lansoprazole (75.0%, P < 0.05) in decreasing acid regurgitation. Finally, pantoprazole and rabeprazole (95.2% and 100%) were also more effective vs lansoprazole (82.6%, P < 0.05) in decreasing epigastric pain.CONCLUSION: In elderly patients, pantoprazole and rabeprazole were significantly more effective than omeprazole in healing esophagitis and than omeprazole or lansoprazole in improving symptoms. H pylori infection did not influence the healing rates of esophagitis after a short-term treatment with PPI. | Alberto Pilotto Marilisa Franceschi Gioacchino Leandro Carlo Scarcelli Luigi Piero D'Ambrosio Francesco Paris Vito Annese Davide Seripa Angelo Andriulli Francesco Di Mario | 2007 | World Journal of Gastroenterology2007，13，33： | 5 |
| 4 | Thermally reconfigurable quantum photonic circuits at telecom wavelength by femtosecond laser micromachining显示文摘The importance of integrated quantum photonics in the telecom band is based on the possibility of interfacing with the optical network infrastructure that was developed for classical communications.In this framework,femtosecond laser-written integrated photonic circuits,which have already been assessed for use in quantum information experiments in the 800-nm wavelength range,have great potential.In fact,these circuits,being written in glass,can be perfectly mode-matched at telecom wavelength to the in/out coupling fibers,which is a key requirement for a low-loss processing node in future quantum optical networks.In addition,for several applications,quantum photonic devices must be dynamically reconfigurable.Here,we experimentally demonstrate the high performance of femtosecond laser-written photonic circuits for use in quantum experiments in the telecom band,and we demonstrate the use of thermal shifters,which were also fabricated using the same femtosecond laser,to accurately tune such circuits.State-of-the-art manipulation of single-and two-photon states is demonstrated,with fringe visibilities greater than 95%.The results of this work open the way to the realization of reconfigurable quantum photonic circuits based on this technological platform. | Fulvio Flamini Lorenzo Magrini Adil S Rab Nicolo Spagnolo Vincenzo D’Ambrosio Paolo Mataloni Fabio Sciarrino Tommaso Zandrini Andrea Crespi Roberta Ramponi Roberto Osellame | 2015 | Light(Science & Applications)2015，4，1： | 5 |
| 5 | Hepatitis C virus-related B cell subtypes in non Hodgkin's lymphoma显示文摘AIM:To evaluate if indolent B cell-non Hodgkin's lymphoma(B-NHL) and diffuse large B-cell lymphoma(DLBCL) in hepatitis C virus(HCV) positive patients could have different biological and clinical characteristics requiring different management strategies.METHODS:A group of 24 HCV related B-NHL patients(11 indolent,13 DLBCL) in whom the biological and clinical characteristics were described and confronted.Patients with DLBCL were managed with the standard of care of treatment.Patients with indolent HCV-related B-NHL were managed with antiviral treatment pegylated interferon plus ribavirin and their course observed.The outcomes of the different approaches were compared.RESULTS:Patients with DLBCL had a shorter duration of HCV infection and a higher prevalence of HCV genotype 1 compared to patients with indolent B-NHL in which HCV genotype 2 was the more frequent genotype.Five of the 9 patients with indolent HCV-relatedB-NHL treated with only antiviral therapy,achieved a complete response of their onco-haematological disease(55%).Seven of the 13 DLBCL patients treated with immunochemotheraphy obtained a complete response(54%).CONCLUSION:HCV genotypes and duration of HCV infection differed between B-NHL subtypes.Indolent lymphomas can be managed with antiviral treatment,while DLBCL is not affected by the HCV infection. | Adriano M Pellicelli Massimo Marignani Valerio Zoli Mario Romano Aldo Morrone Lorenzo Nosotti Giuseppe Barbaro Antonio Picardi Umberto Vespasiani Gentilucci Daniele Remotti Cecilia D'Ambrosio Caterina Furlan Fabrizio Mecenate Ettore Mazzoni Ignazio Majolino Roberto Villani Arnaldo Andreoli Giorgio Barbarini | 2011 | World Journal of Hepatology2011，3，11： | 4 |
| 6 | Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.显示文摘 | Angelo Zullo Giuseppe Scaccianoce Vincenzo De Francesco Valentina Ruggiero Pasquale D’Ambrosio Luigi Castorini Leonilde Bonfrate Lucy Vannella Cesare Hassan Piero Portincasa | 2013 | Clinics and Research in Hepatology and Gastroenterology2013，，： | 4 |
| 7 | 数学史与人类文化数学——民族文化如何介入学习科学的过程显示文摘人类文化数学(同种同文化之数学,ethnomathematics)是一个纲领,它研究知识的产生、传播、体制化和普及,并重视社会文化环境的作用。凭借个人和共同体的文化经验及实践,人类文化数学力争在克服文化障碍的情况下,使儿童能较容易地掌握科学思想。 | Ubiratan D'Ambrosio 赵慧琪 | 1991 | 科学对社会的影响1991，40，4： | 4 |
| 8 | 3D additive-manufactured nanocomposite magnetic scaffolds: Effect of the application mode of a time-dependent magnetic field on hMSCs behavior显示文摘Over the past few years,the influence of static or dynamic magnetic fields on biological systems has become a topic of considerable interest.Magnetism has recently been implicated to play significant roles in the regulation of cell responses and,for this reason,it is revolutionizing many aspects of healthcare,also suggesting new opportunities in tissue engineering.The aim of the present study was to analyze the effect of the application mode of a time-dependent magnetic field on the behavior of human mesenchymal stem cells(hMSCs)seeded on 3D additivemanufactured poly(3-caprolactone)/iron-doped hydroxyapatite(PCL/FeHA)nanocomposite scaffolds. | Ugo D'Amora Teresa Russo Antonio Gloria Virginia Rivieccio Vincenzo D'Anto Giacomo Negri Luigi Ambrosio Roberto De Santis | 2017 | Bioactive Materials2017，2，3： | 3 |
| 9 | 面向控制的多次喷射柴油机仿真模型建模方法显示文摘基于累积燃油质量方法的燃烧模型,建立了多次喷射柴油机零维预测燃烧模型,考虑了燃油蒸发吸热、缸壁传热、化学能释放、泵功损失和摩擦损失,为满足实时性要求,对显式放热率和缸压进行了简化重构.将柴油机运行参数和一些衍生参数作为模型中各个因变量的候选自变量集,以幂函数为基础函数采用敏感度分析筛选出各个因变量对应的自变量集,并通过分析提出了一些改善措施,最终确定各个因变量和对应自变量集之间的映射关系.在稳态工况和重型车辆发动机瞬态测试循环(WHTC)测试了该模型的预测性能,并在ETAS ES910型快速原型设备上测试了该模型的计算耗时,结果表明:在稳态工况,对燃烧中心(MFB 50)、最高燃烧压力和平均有效压力的预测精度均方根误差(RMSE)分别为0.631°CA、0.182 MPa和0.0153 MPa;在瞬态工况,其预测精度RMSE分别为1.2°CA、1.05 MPa和0.07 MPa;该模型计算耗时约为350μs,满足燃烧过程实时控制的要求. | 胡松 王贺春 王银燕 杨福源 Finesso R D’ambrosio S | 2020 | 内燃机学报2020，38，5： | 2 |
| 10 | Ultrasound evaluation of liver fibrosis: preliminary experience with acoustic structure quantification (ASQ) software显示文摘 | Paolo Ricci Chiara Marigliano Vito Cantisani Andrea Porfiri Andrea Marcantonio Pietro Lodise Ugo D’Ambrosio Giancarlo Labbadia Elena Maggini Ester Mancuso Giovanna Panzironi Mattia Segni Caterina Furlan Raffaele Masciangelo Gloria Taliani | 2013 | La radiologia medica2013，，6： | 2 |
| 11 | Interferon gamma decreses hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis显示文摘 | Baroni GS Ambrosio D Cuto P | 1996 | Hepatology1996，23，5： | 1 |
| 12 | Percutaneous coronary intervention utilizing a new endothelial progenitor cells antibody-coated stent: a prospective singlecenter registry in high-risk patients显示文摘 | MIGLIONICO M PATTI G D'AMBROSIO A | 2008 | Catheter Cardiovasc Interv2008，71，5： | 1 |
| 13 | A differential proteomic approach to identify proteins associated with thyroid cell transformation显示文摘 | Paron I D′Ambrosio C Scaloni A | | 0，，01： | 1 |
| 14 | Numerical Instabilities in Upwind Methods: Analysis and Cures for the “Carbuncle” Phenomenon显示文摘 | Maurizio Pandolfi Domenic D’Ambrosio | 2001 | Journal of Computational Physics2001，，2： | 1 |
| 15 | Postoperative delirium 显示文摘 | Cavaliere F D'Ambrosio F Volpe C | 2005 | Curr Drug Targets2005，6，7： | 1 |
| 16 | Pathophysiology of pediatric obstructive sleep apnea显示文摘 | Katz ES D' Ambrosio CM | 2008 | Proc Am Thorac Soc2008，5，： | 1 |
| 17 | Inhibition of IL- 12 production by 1,25dihydroxyvitamin Dinvolvement of NF - kappaB down regulation in transcriptional repression of the P40 gene 显示文摘 | D CIPPTELLI M COCCIOLO M G | 1998 | J Clin Invest1998，101，1： | 1 |
| 18 | Irbesartan reduces the albumin excretion rate in microalbuminuric type 2 diabetic patients independently of hypertension显示文摘 | Carbonara O Persico M Iafusco D Salvatore T D' Ambrosio R | 2002 | Diabetes Care2002，25，11： | 1 |
| 19 | The CD69 receptor:amultipurpose cell surface trigger for hematopoitic cells显示文摘 | Ambrosio D Maria Retal | 1994 | Immunol Today1994，15，10： | 1 |
| 20 | A poly- morphism in the VKORC1 gene is associated with an interindivid- ual variability in the dose anticoagulant effect of warfarin 显示文摘 | D'ANDREA G D'AMBROSIO R L DI PEMA P | 2005 | Blood2005，1，5： | 1 |
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