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| 1 | Contrast-enhanced ultrasound of histologically proven hepatic epithelioid hemangioendothelioma显示文摘AIM: To analyze contrast-enhanced ultrasound(CEUS) features of histologically proven hepatic epithelioid hemangioendothelioma(HEHE) in comparison to other multilocular benign focal liver lesions(FLL).METHODS: Twenty-five patients with histologically proven HEHE and 45 patients with histologically proven multilocular benign FLL were retrospectively reviewed. Four radiologists assessed the CEUS enhancement pattern in consensus.RESULTS: HEHE manifested as a single(n = 3) or multinodular(n = 22) FLL. On CEUS, HEHE showed rim-like(18/25, 72%) or heterogeneous hyperenhancement(7/25, 28%) in the arterial phase and hypoenhancement(25/25, 100%) in the portal venous and late phases(PVLP), a sign of malignancy. Eighteen patients showed central unenhanced areas(18/25, 72%); in seven patients(7/25, 28%), more lesions were detected in the PVLP. In contrast, all patients with hemangioma and focal nodular hyperplasia showed hyperenhancement as the most distinctive feature(P < 0.01).CONCLUSION: CEUS allows for characterization of unequivocal FLL. By analyzing the hypoenhancement in the PVLP, CEUS can determine the malignant nature of HEHE. | Yi Dong Wen-Ping Wang Vito Cantisani Mirko D'Onofrio Andre Ignee Lorenzo Mulazzani Adrian Saftoiu Zeno Sparchez Ioan Sporea Christoph F Dietrich | 2016 | World Journal of Gastroenterology2016，22，19： | 21 |
| 2 | Liver metastases:Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance显示文摘The development of ultrasound contrast agents with excellent tolerance and safety profiles has notably improved liver evaluation with ultrasound(US)for several applications,especially for the detection of metastases.In particular,contrast enhanced ultrasonography(CEUS)allows the display of the parenchymal microvasculature,enabling the study and visualization of the enhancement patterns of liver lesions in real time and in a continuous manner in all vascular phases,which is similar to contrast-enhanced computed tomography(CT)and contrast-enhanced magnetic resonance imaging.Clinical studies have reported that the use of a contrast agent enables the visualization of more metastases with significantly improved sensitivity and specificity compared to baseline-US.Furthermore,studies have shown that CEUS yields sensitivities comparable to CT.In this review,we describe the state of the art of CEUS for detecting colorectal liver metastases,the imaging features,the literature reports of metastases in CEUS as well as its technique,its clinical role and its potential applications.Additionally,the updated international consensus panel guidelines are reported in this review with the inherent limitations of this technique and best practice experiences. | Vito Cantisani Hektor Grazhdani Cristina Fioravanti Maria Rosignuolo Fabrizio Calliada Daniela Messineo Maria Giulia Bernieri Adriano Redler Carlo Catalano Ferdinando D’Ambrosio | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 3 | Pediatric nonalcoholic fatty liver disease:A clinical and laboratory challenge显示文摘The true prevalence of pediatric nonalcoholic fatty liver disease (NAFLD) is unknown. Challenges in determin ing the population prevalence of NAFLD include the type of test (and the reference intervals used to define normal and abnormal), the type of population (general population, hospital series), the demographic characteristics of the population sampled, and the nat ure of the study design. The natural history of pediat ric NAFLD remains uncertain. The issue of when to perform a liver biopsy in children with suspected NAFLD remains controversial. Children with NAFLD but normal alanine aminotransferase are rarely investigated. However, evidence of alterations in glucose metabolism parameters should prompt a better understanding of the natural history of pediatric NAFLD not only in terms of the progression of liver disease but also regarding its potential relationship with other health outcomes such as type 2 diabetes mellitus and cardiovascular disease. This evidence could make liver biopsy mandatory in the majority of cases at risk of progressive and severe hepatic and extrahepatic disease. This conclusion, however, raises the question of the feasibility of liver biopsy assessment in an extremely large at risk popul ation, and of the cost/effectiveness of this policy. There is a considerable, continuous interest in reliable, noninv asive alternatives that will allow the prognosis of pediat ric NAFLD to be followed in large community or populat ionbased studies. | Lucia Pacifico Eleonora Poggiogalle Vito Cantisani Guendalina Menichini Paolo Ricci Flavia Ferraro Claudio Chiesa | 2010 | World Journal of Hepatology2010，2，7： | 6 |
| 4 | Acoustic Radiation Force Impulse (ARFI) ultrasound imaging of solid focal liver lesions显示文摘 | A. Gallotti M. D’Onofrio L. Romanini V. Cantisani R. Pozzi Mucelli | 2011 | European Journal of Radiology2011，，3： | 3 |
| 5 | EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 1: Basic Principles and Technology显示文摘 | J. Bamber D. Cosgrove C. Dietrich J. Fromageau J. Bojunga F. Calliada V. Cantisani J.-M. Correas M. D’Onofrio E. Drakonaki M. Fink M. Friedrich-Rust O. Gilja R. Havre C. Jenssen A. Klauser R. Ohlinger A. Saftoiu F. Schaefer I. Sporea F. Piscaglia | 2013 | Ultraschall in Med2013，，02： | 2 |
| 6 | Ultrasound evaluation of liver fibrosis: preliminary experience with acoustic structure quantification (ASQ) software显示文摘 | Paolo Ricci Chiara Marigliano Vito Cantisani Andrea Porfiri Andrea Marcantonio Pietro Lodise Ugo D’Ambrosio Giancarlo Labbadia Elena Maggini Ester Mancuso Giovanna Panzironi Mattia Segni Caterina Furlan Raffaele Masciangelo Gloria Taliani | 2013 | La radiologia medica2013，，6： | 2 |
| 7 | Benigne und maligne Brusttumoren: Aussagekraft des Real-Time-kontrastverst?rkten Ultraschalls gegenüber MRT显示文摘 | P Ricci V Cantisani L Ballesio E Pagliara E Sallusti F Drudi F Trippa F Calascibetta S Erturk M Modesti R Passariello | 2007 | Ultraschall in Med2007，，01： | 2 |
| 8 | Prospective evalua- tion of multiparametric ultrasound and quantitative elastosonography in the differential diagnosis of benign and malignant thyroid nodules : Preliminary experience显示文摘 | Cantisani V D' Andrea V Biancari F | 2012 | Eur J Radiol2012，81，10： | 1 |
| 9 | Diagnostic accuracy and interobserver agreement of quasistatic ultrasound elastography in the diagnosis of thyroid nodules显示文摘 | Cantisani V Lodise P Di Rocco G | 2014 | Ultraschall Med2014，23，： | 1 |
| 10 | Glycerol for acute stroke显示文摘 | Righetti E Celani MG Cantisani T | 2006 | Cochrane Database Syst Rev2006，，00： | 1 |
| 11 | Hydrofiber dressing and wound repair: review of the literature and new patents 显示文摘 | Richetta AG Cantisani C Li VW | 2011 | Recent Pat Inflamm Allergy Drug Discov2011，5，2： | 1 |
| 12 | Neurological complications in liver transplantation显示文摘 | Vecino MC Cantisani G Zanotelli ML | 1999 | Transplant Proc1999，31，7： | 1 |
| 13 | MR imaging features of solid pseudopapillary tumor of the pancreas in adult and pediatric patients显示文摘 | Cantisani V | 2003 | AJR Am J Roentgenol2003，181，2： | 1 |
| 14 | Serum concentrations of IL - 2, IL - 6, IL - 12 and TNF -α in patients with alopecia areata显示文摘 | Rossi A Cantisani C Carlesimo M | 2012 | Int J Immunopathol Pharmacol2012，25，3： | 1 |
| 15 | Prospective comparative evaluation of quantitative-elas- tosonography (Q-elastography) and contrast-enhanced ultrasound for the evaluation of thyroid nodules: prelimi- nary experience 显示文摘 | CANTISANI V CONSORTI F GUERRISI A | 2013 | EurJ Radiol2013，82，11： | 1 |
| 16 | Prospective comparative evaluation of quantitative-elastosonography (Q-elastography) and contrast-enhanced ultrasound for the evaluation of thyroid nodules: Preliminary experience显示文摘 | V. Cantisani F. Consorti A. Guerrisi I. Guerrisi P. Ricci M. Di Segni E. Mancuso L. Scardella F. Milazzo F. D’Ambrosio A. Antonaci | 2013 | European Journal of Radiology2013，，： | 1 |
| 17 | Serum uric acid and its association with metabolic syndrome and carotid atherosclerosis in obese children显示文摘 | Pacifico L Cantisani V Anania C | 2009 | Eur J Endocrinol2009，160，： | 1 |
| 18 | Intrahepaticperipheral cholangiocarcinoma (IPCC) : comparison between perfusion ultrasound and CT imaging 显示文摘 | Donofrio M Vecchiato F Cantisani V | 2008 | Radiol Med2008，113，1： | 1 |
| 19 | Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity显示文摘 | Scudiero O Galdiero S Cantisani M | 2010 | Antimierob Agents Chemother2010，54，6： | 1 |
| 20 | Role of lowmechanical index CEUS in the differentiation between low and high grade bladder carcinoma: a pilot study 显示文摘 | Drudi F M Cantisani V Liberatore M | 2010 | Ultraschall Med2010，31，6： | 1 |
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