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| 1 | Pancreatic trauma: The role of computed tomography for guiding therapeutic approach显示文摘AIM: To evaluate the role of computed tomography(CT) for diagnosing traumatic injuries of the pancreas and guiding the therapeutic approach.METHODS: CT exams of 6740 patients admitted to our Emergency Department between May 2005 and January 2013 for abdominal trauma were retrospectively evaluated. Patients were identified through a search of our electronic archive system by using such terms as 'pancreatic injury', 'pancreatic contusion', 'pancreatic laceration', 'peri-pancreatic fluid', 'pancreatic active bleeding'. All CT examinations were performed before and after the intravenous injection of contrast material using a 16-slice multidetector row computed tomography scanner. The data sets were retrospectively analyzed by two radiologists in consensus searching for specific signs of pancreatic injury(parenchymal fracture and laceration, focal or diffuse pancreatic enlargement/edema, pancreatic hematoma, active bleeding, fluid between splenic vein and pancreas) and non-specific signs(inflammatory changes in peri-pancreatic fat and mesentery, fluid surrounding the superior mesentericartery, thickening of the left anterior renal fascia, pancreatic ductal dilatation, acute pseudocyst formation/peri-pancreatic fluid collection, fluid in the anterior and posterior pararenal spaces, fluid in transverse mesocolon and lesser sac, hemorrhage into peri-pancreatic fat, mesocolon and mesentery, extraperitoneal fluid, intraperitoneal fluid).RESULTS: One hundred and thirty-six/Six thousand seven hundred and forty(2%) patients showed CT signs of pancreatic trauma. Eight/one hundred and thirty-six(6%) patients underwent surgical treatment and the pancreatic injures were confirmed in all cases. Only in 6/8 patients treated with surgical approach, pancreatic duct damage was suggested in the radiological reports and surgically confirmed in all cases. In 128/136(94%) patients who underwent non-operative treatment CT images showed pancreatic edema in 97 patients, hematoma in 31 patients, fluid between splenic vein and pancreas in 113 patients. Non-specific CT signs of pancreatic injuries were represented by peri-pancreatic fat stranding and mesentery fluid in 89% of cases, thickening of the left anterior renal fascia in 65%, pancreatic ductal dilatation in 18%, acute pseudocyst/peri-pancreatic fluid collection in 57%, fluid in the pararenal spaces in 45%, fluid in transverse mesocolon and lesser sac in 29%, hemorrhage into peri-pancreatic fat, mesocolon and mesentery in 66%, extraperitoneal fluid in 66%, intra-peritoneal fluid in 41% cases.CONCLUSION: CT represents an accurate tool for diagnosing pancreatic trauma, provides useful information to plan therapeutic approach with a detection rate of 75% for recognizing ductal lesions. | Marco Moschetta Michele Telegrafo Valeria Malagnino Laura Mappa Amato A Stabile Ianora Dario Dabbicco Antonio Margari Giuseppe Angelelli | 2015 | World Journal of Radiology2015，7，11： | 4 |
| 2 | Source origin of trace elements in PM from regional background, urban and industrial sites of Spain显示文摘 | X. Querol M. Viana A. Alastuey F. Amato T. Moreno S. Castillo J. Pey J. de la Rosa A. Sánchez de la Campa B. Artí?ano P. Salvador S. García Dos Santos R. Fernández-Patier S. Moreno-Grau L. Negral M.C. Minguillón E. Monfort J.I. Gil A. Inza L.A. Ortega J.M | 2007 | Atmospheric Environment2007，，34： | 2 |
| 3 | New insights into the pathogenesis of vitiligo:imbalance of epidermal cytokines at sites of lesions显示文摘 | Moretti S Spallanzani A Amato L | 2002 | Pigment Cell Res2002，15，2： | 2 |
| 4 | Neuronal and glial properties coexist in a novel mouse CNS immortalized cell line显示文摘 | Tino A Pernas Alonso R | 1999 | Exp Cell Res1999，252，2： | 1 |
| 5 | A semantic en- riched data model for sensor network interoperability 显示文摘 | Amato F Casola V Gaglione A | 2011 | Simulation Modelling Practice and Theory2011，19，8： | 1 |
| 6 | Mitrani-Rosenbaum S:Distinctive patterns of microRNA expression in primary muscular disorders显示文摘 | Eisenberg I Eran A Nishino I Moggio M Lamperti C Amato AA Lidov HG Kang PB North KN | | 0，，： | 1 |
| 7 | Molecular and functional analysis of the large 5' promoter region of CFTR gene revealed pathogenic mutations in CF and CFTR-related disorders显示文摘 | Giordano S Amato F Elce A | 2013 | J Mol Diagn2013，15，3： | 1 |
| 8 | In situ synthesis of TiC-TiB_2-hBN-SiC composites through SHS显示文摘 | MOSSINO P DEORSOLAF A VALLAUR1 D AMATO I | 2004 | Ceramics International2004，30，8： | 1 |
| 9 | Thyroid hormone action in chronic kidney disease显示文摘 | Amato AA Santos GM Neves-Fde A | 2008 | Curr Opin Endocrinol Diabetes Obes2008，15，5： | 1 |
| 10 | New insight into the pathogenesis of vitiligo:imbalance of epidennal cytokines at site of lesion显示文摘 | Moretti S Spallanzani A Amato L | 2002 | Pigment Cell Res2002，15，2： | 1 |
| 11 | Phase Ⅰ/Ⅱ study of thalidomide in combination with interleukin-2 in patients with matastatic renal cell carcinoma显示文摘 | Amato R J Morgan M Rawat A | 2006 | Cancer2006，106，7： | 1 |
| 12 | Glucagon like peptide 2 relaxes mouse stomach through vaosactive intestinal peptide realease 显示文摘 | Amato A Baldassno S Serio R | 2009 | Am J Physiol Gastrointest Liver Physio12009，296，3： | 1 |
| 13 | Determination of sunscreen agents in cosmetic products by reversed phase high performance liquid chromatography显示文摘 | GAGLIARD L AMATO A BASIIL A | 1987 | Chromatographyt1987，6，40： | 1 |
| 14 | Regional energy demand responses to climate change methodology and application to the commonwealth of Massachusetts 显示文摘 | Amato A D Ruth M Kirshen P | 2005 | Climate Change2005，71，1： | 1 |
| 15 | Postintervention serum TSH levels may be useful to diffenrentiate patients who should undergo levothyroxine suppressive therapy after thyroid surgery for multinodular goiter in a region with moderate iodine deficiency显示文摘 | Rotondi M Amato G Del Buono A | 2000 | Thyroid2000，10，12： | 1 |
| 16 | Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins显示文摘 | Hussein T S Froiland D A Amato F | 2005 | J Cell Sci2005，118，22： | 1 |
| 17 | Soil microbial biomass: its assay and role in turnover organic matter C and N 显示文摘 | LADD J N AMATO M VEEN H A | 2004 | Soil Biology & Biochemistry2004，36，： | 1 |
| 18 | Carcinosarcoma of the liver with mesenchymal differentiation: a case report显示文摘 | Leger-Ravet MB Borgonovo G Amato A | 1996 | Hepatogas- troenterology1996，43，： | 1 |
| 19 | Water-aided colonoscopy: a systematic review 显示文摘 | LEUNG FW AMATO A ELL C | 2012 | Gastrointest Endosc2012，76，3： | 1 |
| 20 | Constipation in the elderly:management strategies显示文摘 | Spinzi G Amato A Imperiali G | 2009 | Drug Aging2009，26，： | 1 |
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