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| 1 | 液相萃取-高效液相色谱-串联质谱联用测定污泥中的全氟化合物显示文摘全氟化合物是一种新型持久性有机污染物,污水处理厂是其一个主要污染来源。目前还没有建立起一种统一的污泥样品中全氟化合物的分析方法。本文报道了一种基于液相萃取和高效液相色谱-串联质谱联用技术测定污泥中的7种全氟烷基羧酸及其2种不饱和氟调酸前体物、2种全氟烷基磺酸及其5种磺酰胺衍生物前体物的方法。实验对萃取剂(甲醇)的pH值、超声萃取温度与时间、洗脱剂体积进行了优化,确定了中性溶剂、40℃下超声萃取10min,Envicarbon柱净化的前处理方法,并成功地应用于实际污泥样品中全氟化合物的测定。方法的回收率为74%~141%(不饱和氟调酸除外),线性范围为0.1~20μg/L(羧酸系列)及0.25~50μg/L(磺酸系列)内线性关系良好(r2>0.99),定量限为0.6~30μg/kg(干重)。内标物质的使用可有效消除环境基质引起的仪器离子抑制现象,使定量更加准确。 | 章涛 孙红文 ALDER Alfredo C. GERECKE Andreas C. MULLER Claudia | 2010 | 色谱2010，28，5： | 20 |
| 2 | Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘 | Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce | 2010 | Lancet Oncology2010，，2： | 4 |
| 3 | E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer显示文摘 | Fabio Petrocca Rosa Visone Mariadele Rapazzotti Onelli Manisha H. Shah Milena S. Nicoloso Ivana de Martino Dimitrios Iliopoulos Emanuela Pilozzi Chang-Gong Liu Massimo Negrini Luigi Cavazzini Stefano Volinia Hansjuerg Alder Luigi P. Ruco Gustavo Baldassar | 2008 | Cancer Cell2008，，3： | 4 |
| 4 | Status of precision medicine approaches to traumatic brain injury显示文摘Traumatic brain injury(TBI)is a serious condition in which trauma to the head causes damage to the brain,leading to a disruption in brain function.This is a significant health issue worldwide,with around 69 million people suffering from TBI each year.Immediately following the trauma,damage occurs in the acute phase of injury that leads to the primary outcomes of the TBI.In the hours-to-days that follow,secondary damage can also occur,leading to chronic outcomes.TBIs can range in severity from mild to severe,and can be complicated by the fact that some individuals sustain multiple TBIs,a risk factor for worse long-term outcomes.Although our knowledge about the pathophysiology of TBI has increased in recent years,unfortunately this has not been translated into effective clinical therapies.The U.S.Food and Drug Administration has yet to approve any drugs for the treatment of TBI;current clinical treatment guidelines merely offer supportive care.Outcomes between individuals greatly vary,which makes the treatment for TBI so challenging.A blow of similar force can have only mild,primary outcomes in one individual and yet cause severe,chronic outcomes in another.One of the reasons that have been proposed for this differential response to TBI is the underlying genetic differences across the population.Due to this,many researchers have begun to investigate the possibility of using precision medicine techniques to address TBI treatment.In this review,we will discuss the research detailing the identification of genetic risk factors for worse outcomes after TBI,and the work investigating personalized treatments for these higher-risk individuals.We highlight the need for further research into the identification of higher-risk individuals and the development of personalized therapies for TBI. | Sahithi Reddi Smita Thakker-Varia Janet Alder Anna O.Giarratana | 2022 | Neural Regeneration Research2022，17，10： | 3 |
| 5 | 温度和养护条件对砂浆和混凝土强度增长的影响 | Barbara Lothenbac Corinne Alder Frank Winnefeld Dübendorf/Schweiz und Peter Lunk Zürich/Schweiz 杨先坤 | 2007 | 商品混凝土2007，0，2： | 3 |
| 6 | Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘 | Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce | 2010 | Lancet Oncology2010，，2： | 2 |
| 7 | Comprehensive miRNA profiling of surgically staged endometrial cancer显示文摘 | David E. Cohn Muller Fabbri Nicola Valeri Hansjuerg Alder Iouri Ivanov Chang-Gong Liu Carlo M. Croce Kimberly E. Resnick | 2010 | American Journal of Obstetrics and Gynecology2010，，6： | 2 |
| 8 | Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography–mass spectrometry显示文摘 | Michel Y Haller Stephan R Müller Christa S McArdell Alfredo C Alder Marc J.-F Suter | 2002 | Journal of Chromatography A2002，，1： | 2 |
| 9 | Antibody responses of variable lymphocyte receptors in the lamprey显示文摘 | Alder MN Herrin BR Sadlonova A | 2008 | Nat Immunol2008，9，： | 1 |
| 10 | Identification d fluoroquinolone antibiotics as the main source of human genotoxieity in native hospital waatewater显示文摘 | HARTMANN A ALDER A C KOLLER T | 1998 | Environmental Toxicololgy and Chemistry1998，17，： | 1 |
| 11 | Identification of fluoroquinolone antibiotics as the main source of genotoxicity in native hospital wastewater 显示文摘 | Hartmann A Alder A Koller T | 1998 | Environmental Toxicology and Chemistry1998，17，3： | 1 |
| 12 | Association of glycaemia with macrovascular and microvascular complications of type 2 aliabets (UKPDS 35): prospective observational study 显示文摘 | Stratton IM Alder AI Neil HA | 2000 | BMJ2000，321，7258： | 1 |
| 13 | Doppler ultrasound flow imaging in the study of breast cancer:Preliminary findings显示文摘 | Alder DD Carson PL Rubin JM | 1990 | Ultrasound Med Biol1990，16，6： | 1 |
| 14 | Ground state of the electron gas by a stochastic method显示文摘 | Ceperley D M Alder B J | 1980 | Physical Review Letters1980，45，7： | 1 |
| 15 | Depression and anxietyduring pregnancy: A risk fac- tor for obstetric, fetal and neonatal out- come? A critical review of the literature 显示文摘 | Alder J Fink N Bitzer J | 2007 | J Matern Fetal Neonatal Med2007，20，3： | 1 |
| 16 | Doppler ultrasound color flow imaginginthe study of breast cancer: Preliminary findings显示文摘 | Carson PL Rubin JM | 1990 | UItrasound Med Biol1990，16，6： | 1 |
| 17 | Ground state of the electron gas by a stochastic method 显示文摘 | CEPERLEY D M ALDER B J | 1980 | Phys Rev Lett1980，45，7： | 1 |
| 18 | Ground State of the Electron Gas by a Stochastic Method 显示文摘 | Ceperley D M Alder B J | 1980 | Phys Rev Lett1980，45，： | 1 |
| 19 | Clinical usefulness of two-dimension reformed and three-dimension rendered computerized tomographic images 显示文摘 | Marden E Alder DM Thomas D | 1995 | J Oral Maxillofac Surg1995，53，4： | 1 |
| 20 | Comparison of kinetic theory and hydrodynamics for Poiseuille flow显示文摘 | Zheng Y Garcia A L Alder B J | | 0，，3： | 1 |
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