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1078篇 您的检索式:作者名="ADAM M S"
    题名 作者 年代 出处 被引量
1内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A 2018中华高血压杂志2018,26,3:6
2Brain changes in diabetes mellitus patients withgastrointestinal symptoms显示文摘Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock Jens B Frøkjær Klaus Krogh Asbjørn M Drewes 2016World Journal of Diabetes2016,7,2:4
3责任制医疗照护机构——美国的经验与教训显示文摘Hugh Alderwick与同事强调:英国国家健康体系(NHS)的政策制定者应实事求是地看待新型医疗保健模式带来的潜在收益。英格兰国家健康体系(NHS)决策圈都在谈论源自美国的一个新概念——责任制医疗照护机构(ACOs)。英格兰NHS和卫生部长认为ACO(s以及相关的责任制医疗体系)是改进NHS服务的重要途径。Hugh Alderwick Stephen M Shortell Adam D M Briggs Elliott S Fisher 周红霞(译) 肖月(校) 2019中国医院院长2019,0,12:2
4The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan 2007Neurology2007,,24:2
5Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease显示文摘Acloque Hervé Adams Meghan S Fishwick Katherine Bronner-Fraser Marianne Nieto M Angela 2009Journal of Clinical Investigation2009,,6:2
6Hemodynamic response to pumpless extracorporeal membrane oxygenation 显示文摘Chapman J Adams M Alexander S 1990J Thorac Cardiovasc Surg1990,99,4:1
7In vitro and in vivo spin echo diffusion imaging characteristics of sgnovial fluid:Potential non-invasire differentiation of inflammatory and degenerative arthritis显示文摘Eustace S Dimasi M Adam J 2007Skeletal Radiol2007,29,6:1
8The Bcl-2 apoptotic switch in cancer development and therapy显示文摘ADAMS J M CORY S 2007Oncogene2007,26,9:1
9Condensed tannin biosynthesis genes are regulated separately from other flavonoid biosynthesis genes in apple fruit skin显示文摘Adam M T Benjamin E U Robinson S P 2006Plant Science2006,170,:1
10Isolation of transmissible enteritis agent of turkeys in avian embryos 显示文摘Adams N R Hofstad M S 1971Avian Dis1971,15,:1
11Endocan or endothelial cell specific molecule-1 (ESM-1):a potential novel endothelial cell marker and a new target for cancer therapy显示文摘Sarrazin S Adam E Lyon M 2006Biochim Biophys Acta2006,1765,1:1
12Retrieval-induced forgetting in normal age-ing显示文摘Hogge M Adam S Collette F 2008J Neuropsychol2008,2,2:1
13Endocan or endothelial cell specific molecule-1 -(ESM-1):a potential novel endothelial cell marker and a new target for cancer therapy显示文摘Sarrazin S Adam E Lyon M 0,,01:1
14Quality of life after burn injury:the impact of joint contracture显示文摘Leblebici B Adam M Bagis S 0,,06:1
15The Bcl-2 protein family:arbiters of cell survival显示文摘Adams J M Cory S 0,,5381:1
16Evaluation of hemispherical photography for determining plant area index and geometry of a forest stand显示文摘Chen J M Black T A Adams R S 1991Agricultural and Forest Meteorology1991,56,1:1
17Bclo2 genes promotes heamopoietic cells survival and cooperates with C-myc to immortalize pro-B cell 显示文摘Vaux DL Cory S Adams M 1998Nature1998,335,6189:1
18Rindopepimut: a promising im- munotherapeutie for the treatment of glioblastoma multiforme 显示文摘ADAM M S QI J L JOHN H S 2014Immunotherapy2014,6,6:1
19Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids 显示文摘Adams J Behnke M Chen S 1998Bioorg Med Chem Lett1998,8,4:1
20Aeromonas adhesion antigens显示文摘 ADAMS D SAVVAS R S 1987Cellular and Molecular Life Sciences1987,43,4:1
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