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	题名	作者	年代	出处	被引量
1	代谢综合征对症状性脑内动脉狭窄预后的影响显示文摘Background: The metabolic syndrome (MetS) is a cluster of risk factors linked to insulin resistance that increase an individual’s risk of atherosclerotic vascular disease. The authors evaluated the prevalence and prognosis of the MetS among individuals with symptomatic intracranial arterial stenosis. Methods: Patients enrolled in the Warfarin-Aspirin Symptomatic Intracranial Disease trial were evaluated in this post-hoc analysis. Baseline characteristics and outcome were compared in patients with the MetS vs patients without the MetS. Results: Among 476 patients, the prevalence of the MetS was 43%. MetS patients were more likely to be younger, female, and white. During a mean follow-up period of 1.8 years, time to the first of ischemic stroke, myocardial infarction, or vascular death was shorter among patients with the MetS with a hazard ratio (syndrome/no syndrome) of 1.6 (95%CI = 1.1 to 2.4, p = 0.0097). Time to ischemic stroke alone was also shorter among patients with the MetS with a hazard ratio (syndrome/no syndrome) of 1.7 (95%CI = 1.1 to 2.6, p = 0.012). When controlling for individual factors of the definition, MetS was not significant (combined outcome: p = 0.14; ischemic stroke: p = 0.074). Conclusions: The metabolic syndrome is present in about half of individuals with symptomatic intracranial atherosclerotic disease and is associated with a substantially higher risk of major vascular events. The metabolic syndrome may not provide additional ability to predict outcomes beyond the individual factors for patients with intracranial stenosis.	Ovbiagele B. Saver J. L. Lynn M. J. Chimowitz M. 邱伟庆(译)	2006	世界核心医学期刊文摘(神经病学分册)2006，2，9：	12
2	Stenting versus aggressive medical therapy for intracranial arterial stenosis显示文摘	Chimowitz MI Lynn MJ Derdeyn CP		New England Journal of Medicine0，，：	3
3	The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘	E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan	2007	Neurology2007，，24：	2
4	Risk factors associated with major cerebrovascular complications after intracranial stenting显示文摘	F Nahab M J. Lynn S E. Kasner M J. Alexander R Klucznik O O. Zaidat J Chaloupka H Lutsep S Barnwell M Mawad B Lane M I. Chimowitz	2009	Neurology2009，，23：	2
5	Report of three patients显示文摘	Barnett GH Palmer J:Treatment of intractable arterial hemorrhage during stereotactic brain biopsy with thrombin	1991	J Neurosurg1991，74，：	1
6	Warfarin vs aspirin for symptomatic intracranial stenosis:subgroup analyses from WASID显示文摘	Lynn M J Chimowitz MI	2006	Neurology2006，67，：	1
7	Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: a scientific statement for healthcare professionals from the Stroke Council and the Council on Clinical Cardiology of the American Heart Association/American Stroke Association显示文摘	Adams RJ Chimowitz MI Alpert JS	2003	Circulation2003，108，10：	1
8	Stenting versus aggressive medical therapy for intracranial arterial stenosis显示文摘	Chimowitz M I Lynn M J Derdeyn C P	2011	N Engl J Med2011，365，：	1
9	Predictors of ischemic stroke in the territory of a symptomatic intracranial arterial stenosis显示文摘	Chimowitz MI Lynn MJ	2006	Circulation2006，113，：	1
10	Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis显示文摘	Chimowitz MI Lynn MJ Howlett-Smith H	2005	N Engl J Med2005，352，13：	1
11	Transcranil Dopplar assessment of cerebral perfusion reserve in patients with carotid occlusive disease and on evidence of cerebral infarction显示文摘	Chimowitz M I Furlan A J Jones SC	1993	Neurology1993，43，：	1
12	Stroke in patients with fusiform vertebrobasilar aneurysms显示文摘	Pessin MS Chimowitz MI Levine SR	1989	Neurology1989，39，：	1
13	Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis(SAMMPRIS):the final results of a randomised trial显示文摘	Derdeyn C P Chimowitz M I Lynn M J	2014	Lancet2014，383，9914：	1
14	Stenting versusaggressive medical therapy for intracranial arterial stenosis显示文摘	Chimowitz MI Lynn MJ Derdeyn CP	2011	N Engl J Med2011，365，11：	1
15	Stenting versus aggressive medical therapy for intracranial arterial stenosis显示文摘	Chimowitz MI Lynn M J Derdeyn CP	2011	N Engl J Med2011，365，11：	1
16	Warfarin vs aspirin for symptomatic intracranial stenosis: subgroup analyses from WASID 显示文摘	Kasner SE Lynn MJ Chimowitz MI	2006	Neurology2006，67，：	1
17	Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis显示文摘	Chimowitz M I Lynn M J Howlett-Smith H	2005	N Engl J Med2005，352，13：	1
18	Warfarin vs aspirin for symptomatic intracranial stenosis: subgroup analyses from WASID 显示文摘	Kasner S E Lynn M J Chimowitz M I	2006	Neurology2006，67，7：	1
19	Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis显示文摘	Chimowitz MI Lynn MJ Howlett-Smith H	2005	N Eng J Med2005，352，13：	1
20	Stenting versus aggressive medical therapy for intracranial arterial stcnosis显示文摘	Chimowitz MI Lynn M J Derdeyn CP	2011	N Engl J Med2011，365，：	1

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