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| 1 | Seed metabolomic study reveals significant metabolite variations and correlations among different soybean cultivars显示文摘Soybean[Glycine max(L.) Merr.]is one of the world's major crops,and soybean seeds are a rich and important resource for proteins and oils.While 'omics' studies,such as genomics,transcriptomics,and proteomics,have been widely applied in soybean molecular research,fewer metabolomic studies have been conducted for largescale detection of low molecular weight metabolites,especially in soybean seeds.In this study,we investigated the seed metabolomes of 29 common soybean cultivars through combined gas chromatography-mass spectrometry and ultra-performance liquid chromatography-tandem mass spectrometry.One hundred sixty-nine named metabolites were identified and subsequently used to construct a metabolic network of mature soybean seed.Among the 169 detected metabolites,104 were found to be significantly variable in their levels across tested cultivars.Metabolite markers that could be used to distinguish genetically related soybean cultivars were also identified,and metabolitemetabolite correlation analysis revealed some significant associations within the same or among different metabolite groups.Findings from this work may potentially provide the basis for further studies on both soybean seed metabolism and metabolic engineering to improve soybean seed quality and yield. | Hong Lin Jun Rao Jianxin Shi Chaoyang Hu Fang Cheng Zoe A.Wilson Dabing Zhang Sheng Quan | 2014 | Journal of Integrative Plant Biology2014，56，9： | 7 |
| 2 | 一种有效近似建模方法及船舶耐波性代理模型构建(英文)显示文摘船舶耐波性能预报计算过程复杂,会受到诸多设计变量的影响;且采用高精度商业软件如CFD预报船舶性能的计算代价非常高。文章采用拉丁超立方方法进行了设计空间抽样。定义了一个新的综合衡准指标来表达船舶耐波性能,即短期和长期作用下船舶非工作时间百分数。考虑了船舶耐波性能中的五个运动方向:横摇、纵摇、转艏、横荡和升沉。为提高船舶耐波性能计算效率,一种有效的近似建模方法—单参数Lagrangian支持向量回归算法被用于训练并构建代理模型以预报船舶耐波性能,且该算法是由作者在过去的研究工作中首次提出。以海洋平台支援船(OSV)为例,采用SPL-SVR算法预报船舶耐波性能,并与基于NAPA计算仿真结果、人工神经网络和经典支持向量回归算法进行对比。该文考虑OSV的两种速度,建立了海洋平台支援船短期作用下非工作时间百分数的耐波性能响应面模型,结果显示采用SPL-SVR算法建立的船舶耐波性能响应面模型比较适合船型初步设计的工程实际应用,并具有较高的计算效率。 | 李冬琴 Philip A.WILSON 蒋志勇 赵欣 | 2016 | 船舶力学2016，20，3： | 3 |
| 3 | 查看详情显示文摘 | P.Bushev D.Rotter A.Wilson F.Dubin C.Becher J.Eschner R.Blatt V.Steixner P.Rabl and P.Zoller | | 0，，04： | 1 |
| 4 | 船舶操纵性能及其代理模型构建(英文)显示文摘为了提高船舶操纵性能计算效率,文章结合基于NAPA计算仿真结果和支持向量回归方法预报海洋平台支援船的操纵性能,在收集足够相关船型信息前提下,采用能够合理探索设计空间和抽样的拉丁超立方方法获取了30条样本船型数据。通过NAPA仿射变化、位移转换及根据船型设计变量进行局部调整从而生成系列船型以表达船体几何形状。针对每个船型,分别计算了5项操纵性衡准指标:进距、战术直径、横距、10°舵角第一超越角和20°舵角第一超越角。为提高船舶操纵性能的计算效率,文中利用作者早先新提出的一种单参数Lagrangian支持向量回归算法来训练并构建代理模型以预报船舶操纵性能,该算法整合了Laplace损失函数,仅采用单参数控制计算误差并于置信区间中增加了b^2/2项。以海洋平台支援船为例,采用SPL-SVR算法预报船舶操纵性能,并与基于NAPA计算仿真结果、人工神经网络、经典支持向量回归算法进行对比。不需要昂贵的仿真代码计算,文中采用SPL-SVR算法建立的船舶操纵性能响应面模型比较适合船型初步设计的工程实际应用,并具有较好的效率和适用性。 | 李冬琴 Philip A.WILSON 蒋志勇 | 2015 | 船舶力学2015，19，12： | 1 |
| 5 | International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International workshop显示文摘 | Wendell A.Wilson Azzudin E.Gharavi TakaoKoike Michael D.Lockshin D. WareBranch Jean‐CharlesPiette RobinBrey RonaldDerksen E. NigelHarris Graham R. V.Hughes Douglas A.Triplett Munther A.Khamashta | 2001 | Arthritis & Rheumatism2001，，7： | 1 |
| 6 | From productivism to post‐productivism … and back again? Exploring the (un)changed natural and mental landscapes of European agriculture显示文摘 | Geoff A.Wilson | 2002 | Transactions of the Institute of British Geographers2002，，1： | 1 |
| 7 | On-line Gas Sensor显示文摘 | T Mcgrail A.Wilson | | 0，，： | 1 |
| 8 | Safeguarding Biodiversity and Ecosystem Services in the Little Karoo, South Africa显示文摘 | BENIS N.EGOH BELINDAREYERS JOSIECARWARDINE MICHAELBODE PATRICK J.O’FARRELL KERRIE A.WILSON HUGH P.POSSINGHAM MATHIEUROUGET WILLEMDe LANGE DAVID M.RICHARDSON RICHARD M.COWLING | 2010 | Conservation Biology2010，，4： | 1 |
| 9 | A comparison of the amount of food served and consumed according to meal service system显示文摘 | A.Wilson S.Evans G.Frost | 2001 | Journal of Human Nutrition and Dietetics2001，，4： | 1 |
| 10 | International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International workshop显示文摘 | Wendell A.Wilson Azzudin E.Gharavi TakaoKoike Michael D.Lockshin D. WareBranch Jean‐CharlesPiette RobinBrey RonaldDerksen E. NigelHarris Graham R. V.Hughes Douglas A.Triplett Munther A.Khamashta | 2001 | Arthritis & Rheumatism2001，，7： | 1 |
| 11 | Severe community‐acquired pneumonia: an Australian perspective显示文摘 | P. A.Wilson J.Ferguson | 2005 | Internal Medicine Journal2005，，12： | 1 |
| 12 | Disruption of Arabidopsis thaliana MYB26 results in male sterility due to non‐dehiscent anthers显示文摘 | SabineSteiner‐Lange Ulrike S.Unte LucaEckstein CaiyunYang Zoe A.Wilson ElmonSchmelzer KoenDekker HeinzSaedler | 2003 | The Plant Journal2003，，4： | 1 |
| 13 | Medical micro-and nanomotors in the body显示文摘Attributed to the miniaturized body size and active mobility,micro-and nanomotors(MNMs)have demonstrated tremendous potential for medical applications.However,from bench to bedside,massive efforts are needed to address critical issues,such as cost-effective fabrication,on-demand integration of multiple functions,biocompatibility,biodegradability,controlled propulsion and in vivo navigation.Herein,we summarize the advances of biomedical MNMs reported in the past two decades,with particular emphasis on the design,fabrication,propulsion,navigation,and the abilities of biological barriers penetration,biosensing,diagnosis,minimally invasive surgery and targeted cargo delivery.Future perspectives and challenges are discussed as well.This review can lay the foundation for the future direction of medical MNMs,pushing one step forward on the road to achieving practical theranostics using MNMs. | Huaan Li Fei Peng Xiaohui Yan Chun Mao Xing Ma Daniela A.Wilson Qiang He Yingfeng Tu | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 0 |
| 14 | Utilization of leather fibrous wastes for the production of reconstituted fibric materials:heavy metal determination and removal显示文摘Incomprehension concerning heavy metal containing finished solid leather wastes leads to environmental pollution.Conversion of these solid leather waste into energy and resource efficient products proves to be challenging.However,leather microfibres(LMF)were isolated from these heavy metal containing finished solid leather wastes.These heavy metal contain LMF further processed into metal reduction LMF.The metal reduction LMF were investigated for their heavy metal removal efficiency and toxicity analysis.The Cr(III)and Cr(VI)content of LMF was<1000μg/mL and<800μg/mL,respectively.Toxicity estimation was proved that the LMF had less than 1%.The study attempt to prepare reconstituted fibric materials(RFM)from metal reduction LMF and cellulose nanofibres(CNF).RFM were characterized for their physicochemical and mechanical properties.Hence,the study has proved a novel concept of RFM production which is recyclable,environmental friendly and cost effective. | Rethinam Senthil Serdar Batıkan Kavukcu A.Wilson Aruni Urana Dandar Bahri Basaran Vijayan Sumathi | 2022 | Waste Disposal and Sustainable Energy2022，4，1： | 0 |
| 15 | Correction to:EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation显示文摘Figure 1.EGFR activation promotes TLR4 phosphorylation and cell surface expression of TLR4 in response to LPS.(A and B)BMDM were treated with LPS(1μg/mL)for 6,12,or 24 h in the presence or absence of pretreatment of PD or TAPI-1.(A)Flow cytometry analysis of cell surface TLR4 intensity in BMDM.(B)Flow cytometry analysis of cell surface TLR4 intensity in BMDM.(C and D)WT(C57BL76)mice were treated with LPS(10 mg/kg,i.p.).In some groups,mice were pretreated with erlotinib(100 mg/kg,gavage administration)at 30 min prior to LPS i.p. | Jing Tang Bowei Zhou Melanie J.Scott Linsong Chen Dengming Lai Erica K.Fan Yuehua Li Qiang Wu Timothy R.Billiar Mark A.Wilson Ping Wang Jie Fan | 2020 | Protein & Cell2020，11，8： | 0 |
| 16 | First detection of F1534C knockdown resistance mutation in Aedes aegypti(Diptera:Culicidae)from Cameroon显示文摘Background: Aedes borne viral diseases,notably dengue,are increasingly reported in Cameroon with Aedes aegypti being a major vector.Data on insecticide resistance of this vector and underlying mechanisms needed for outbreak preparedness remain scarce in Cameroon.Here,we present the nationwide distribution of insecticide resistance in Ae.aegypti and investigate the potential resistance mechanisms involved.Methods:: Immature stages of Ae.aegypti were collected between March and July 2017 in 13 locations across Cameroon and reared until G1/G2/G3 generation.Larval,adult bioassays,and piperonyl butoxide(PBO)synergist assays were carried out according to World Health Organization guidelines.F1534C mutation was genotyped using allele specific polymerase chain reaction in field collected adults(Go)and the polymorphism of the sodium channel gene was assessed.Theχ2 test was used to compare the mortality rate between bioassays with insecticides only and bioassays after preexposure to PBO synergist.Results: Larval bioassay revealed that all the three populations tested with temephos were susceptible.Adult bioassays showed a good level of susceptibility toward both pyrethroids tested,0.25%permethrin and 0.05%deltamethrin,with six out of 10 populations susceptible.However,two populations(Douala and Edéa)were resistant(deltamethrin[73.2–92.5%mortality],permethrin[2.6–76.3%mortality]).The resistance to 4%dichlorodiphenyltrichloroethane was observed in four out of 10 populations tested(16.8–87.1%mortality).Resistance was also reported to carbamates including 0.1%propoxur(60.8–87.1%mortality)and to 0.1%bendiocarb(82.9%mortality).All populations tested were fully susceptible to 1%fenitrothion.A partial recovery of susceptibility was observed in the pyrethroid resistant population of Douala after pre-exposed to PBO suggesting the implication of cytochrome P450 monoxygenases permethrin resistance.Genotyping and sequencing detected the F1534C kdr mutation in the two pyrethroid resistant locations of Edéa and Douala,with allelic frequency of 3.3%and 33.3%respectively.However,the high genetic diversity of the sodium channel gene supports the recent introduction of this mutation in Cameroon.Conclusions: This study revealed the contrasting resistance profiles to insecticides of Ae.aegypti populations in Cameroon suggesting that,instead of a unique nationwide control approach,a regionally adapted strategy will be needed to control this vector.The localised distribution of the F1534C kdr mutation supports this region-specific control strategy. | Aurelie P.Yougang Basile Kamgang Theodel A.Wilson Bahun Armel N.Tedjou Daniel Nguiffo-Nguete Flobert Njiokou Charles S.Wondji | 2020 | Infectious Diseases of Poverty2020，9，6： | 0 |
| 17 | 用含气井微地震监测油田显示文摘微地震提供了关于储层中应力变化的直接四维信息,应力变化是由注入和生产操作导致的。这些应力变化放出地震能量束和关于所有由油田操作引起的小的滑动事件的信息。直到最近,微地震监测要求在暂停不用的监测井中部署地震传感器。现在在含气井中部署地震监测是可能的。这样的监测在有效注入或生产过程中以及在监测井很少能获得的海上环境中可以进行。 | Stephen A.Wilson 杜东(译) | 2009 | 石油科技动态2009，，10： | 0 |
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