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| 1 | Acrylic Acid-RGD as a Biomimetic Surface Modifier for Poly(ethylene terephthalate)显示文摘The development of the blood compatibility is important to biomaterials.The attachment of human umbilical vein endothelial cells (HUVECs) on substrates that had been covalently grafted with the cell adhesion peptides Arg Gly Asp(RGD) was investigated. The immobilization of the peptide sequences at the surfaces of biomaterials, such as poly(ethylene terephthalate) (PET), is difficult due to an absence of functional groups to support covalent attachment. It is demonstrated a novel method to overcome this problem, by attach the RGD to acrylic acid(AAC), which immobilizes the sequence through adsorption at the PET surface. When coated by AAC RGD, the human umbilical vein endothelial cells (HUVECs) seeded upon the modified PET showed a marked increase in spreading over unmodified PET. The peptides were grafted using two steps: conjugation of AAC with PET film; reaction with PET AAC and immobilization of cell binding peptides RGD. The RGD grafted surface was characterized by X ray photoelectron spectroscopy(XPS) and contact angle measurements. Cell spreading is observed by optional microscopy and scanning electron microscope(SEM). Potentially, this is a feasible method of surface modification that can design many different types of biomaterials with a variety of biomolecules. | QIU Kai 1 , WAN Chang xiu 1 , CHEN Xin 1,LI Tian quan 2 This materials is based upon the work supported under the National Nature Science Fund project of China(29874022) 1 Department of Polymer Science and Engneering, Sichuan University,Chengdu 610065,China 2 Department of Chemistry, Sichuan University,Chengdu 610065,China | 2003 | Chinese Journal of Biomedical Engineering(English Edition)2003，12，1： | 1 |
| 2 | The Management of Manufacturing Flexibility显示文摘 | David | 1994 | California Management Review1994，，： | 1 |
| 3 | Arunee Tabtiang 显示文摘 | The influence of preparation method upon the structure and relaxation characteristics of PMMA/clay composites | 2000 | European Polymer Journal2000，36，： | 1 |
| 4 | Development and Electrochemical Studies of Ruthenium Based Mixed Oxide Catalyst Electrodes for Chlorine Evolution显示文摘Experimental results are presented which allow comparison of the electrochemical performance of RuO 2/Ti, Ru 0 3 Sn 0 7 O 2/Ti and Ru 0 3 V 0 7 O 2/Ti catalysts prepared on a titanium substrate by thermal decomposition from respective precursors. The highest activity for chlorine evolution is observed on the Ru 0 3 V 0 7 O 2/Ti electrode, lower on Ru 0 3 Sn 0 7 O 2/Ti and least on RuO 2/Ti. Voltammograms obtained in the polarisable region are used to characterize the different electrodes. Further more an analysis of the catalytic activity and reaction kinetics of the developed electrodes in NaCl are presented. | L. X. Yang *Department of Chemical and Processing Engineering, University of Newcastle Merz Court, Newcastle upon Tyne NE1 7RUJ. P. G. FarrSchool of Metallurgy and Materials, The University of Birmingham Edgbaston, Birmingham B15 2TT, UK | 2002 | Chemical Research in Chinese Universities2002，18，2： | 1 |
| 5 | 0 显示文摘 | Dehouck Yves Grosfils Aline Folch Benjamin Gilis Dimi- tri Bogaerts Philippe Rooman Marianne Fast and accurate predictions of protein stability changes upon mutations using sta- tistical potentials and neural networks : PoPMuSiC - 2 | 2009 | Bioinformatics2009，25，19： | 1 |
| 6 | II Hydroxyphenylboric acids显示文摘 | Derivatives of phenylboric acid their preparation and action upon bacteria | 1932 | Journal of the American Chemical Society1932，54，： | 1 |
| 7 | 显示文摘 | Singh P Dai B Dhruva B & Widen SG Episomal expression of sense and anlisense insulin-like growth factor (IGF)- binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I | 1994 | Cancer Research1994，54，： | 1 |
| 8 | A model of water quality management under uncertainty显示文摘 | Upon C | 1970 | water resources research1970，6，3： | 1 |
| 9 | Part Ⅱ:Gradient & partial loading显示文摘 | M M Alinia S Kashizadeh Effect of flexibility of substructures upon thermal behaviour of spherical double layer space truss domes | | 0，，07： | 1 |
| 10 | Bone morphoge-netic protein (BMP)and activin type 11 receptors balance BMIO signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells显示文摘 | Upon PD Davies R J Richard C | 2009 | J Biol Chem2009，284，15： | 1 |
| 11 | Surgical strategy for the treatment of sporadic medullary thyroid carcinoma: our experience显示文摘 | upone G Antonino A Rosato A | 2012 | G Chir2012，33，1112： | 1 |
| 12 | Food restriction leads to binge of the brain-derived neurotrophic factor Va166Met polymorphism显示文摘 | Akkermann K Hiio K Villa I et eating dependent upon the effect al | 2011 | Psychiatry Research2011，185，： | 1 |
| 13 | the Case of Brandon,Manitoba显示文摘 | John Everitt Barbara Gfellner.The Effects of Migration upon the Quality of Life of Elderly Movers in a Small Prairie City | | 0，，4： | 1 |
| 14 | TOAST subtypes: its influence ~ decisions of antihypertensive prescription at ischemic stroke patients 显示文摘 | Xu J Liu L upon doctors discharge for Wang Y | 2012 | Patient PreferAdherence2012，6，： | 1 |
| 15 | Effects the granule layer of the dentategurus in male and female adult rats: A morphometric study显示文摘 | Madeira MD Cadete-Leite of hypothyroidism upon A Andrade JP | 1991 | J Comp Neurol1991，313，： | 1 |
| 16 | 跨界全能昂达V819 3G平板电脑显示文摘更快、更高、更强,这是在传统PC时代人们所不断追求的目标,而到了移动互联的今天,更轻、更薄、更久,才是人们真正想要的,而昂达v819 3G版或许从侧面印证了如何实现这三个目标。 | UPON | 2014 | 计算机应用文摘2014，，1： | 0 |
| 17 | DETECTIONOFINCIPIENTDEFECTSINAGEARBOXBYDEMODULATIONOFMESHINGVIBRATIONSIGNATURE显示文摘研究了齿轮箱早期疲劳裂纹的检测方法。依据信号解调原理,提出了一种从复杂振动信号中提取故障信号,求得幅值和相位解调函数的信号处理方法,且在信号采集时,无需使用任何类似于转速计或相位锁定装置产生触发信号。该方法可增强包含故障特征的信号。 | Luo Zhusan The Department of Mechanical Engineering,NUAA29 Yudao Street,Nanjing 210016, P. R. China Fawcett J N The Department of Mechanical,Materials and Manufacturing EngineeringUniversity of Newcastle upon Tyne,Newcastle upon Tyne NE1 7RU,UK | 1996 | Transactions of Nanjing University of Aeronautics and Astronautics1996，13，1： | 0 |
| 18 | 主攻游戏 致家完美电视盒子显示文摘致家完美电视盒子是由金亚科技和完美世界联手打造,它的外形酷似小米电视盒,只是重量略轻。在机身后部,提供了一个HDMI接口、一个USB接口以及一个千兆网接口,扩展能力强,方便用户接驳各种外设。在硬件规格方面,这款电视盒子采用的ARMA91.60Hz双核处理器和Mall400四核GPU,和市面上的同类电视盒子比,致家完美电视盒子的硬件规格显得很强。 | UPON | 2014 | 计算机应用文摘2014，，2： | 0 |
| 19 | Effects of Thermal Activation on the Electrocatalysis of the Ru(0001) Surface显示文摘Variable temperature in situ FTIR spectroscopy has been used as the primary tool to investigate the effects of temperature(10 to 50 ℃) on formaldehyde dissociative adsorption and electro oxidation on the Ru(0001) electrode in perchloric acid solution, and the results were interpreted in terms of the surface chemistry of the Ru(0001) electrode and compared to those obtained during our previous studies on the adsorption of CO under the same conditions. It was found that formaldehyde did undergo dissociative adsorption, even at -200 mV vs . Ag/AgCl, to form linear(CO L) and 3 fold hollow(CO H) binding CO adsorbates. In contrast to the adsorption of CO, it was found that increasing the temperature to 50 ℃ markedly increased the amount of CO adsorbates formed on the Ru(0001) surface from the adsorption of formaldehyde. On increasing the potential, the electro oxidation of the CO adsorbates to CO 2 took place via reaction with the active (1×1) O oxide. A significant increase in the surface reactivity was observed on the RuO 2(100) phase formed at higher potentials. Formic acid was detected as a partial oxidation product during formaldehyde electro oxidation. The data obtained at 50 ℃ are markedly different from those collected at 10 and 25 ℃ in terms of the amount of both CO 2 and formic acid formed and the adsorbed CO L and CO H species observed. These results were rationalized by the thermal effects on both the loosening of the CO adlayer and the activation of surface oxide on increasing the temperature. | Wenfeng Lin ** , Jiamei Jin and Paul A. ChristensenDepartment of Chemistry, Bedson Building, The University, Newcastle upon Tyne, NE1 7RU, UK | 2002 | Chemical Research in Chinese Universities2002，18，2： | 0 |
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