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| 1 | Cryoablation of malignant liver tumors: results of a single center study显示文摘BACKGROUND: Local ablative procedures such as cryo-surgery and thermo-ablation are increasingly employed as a supplement to liver resection for the therapy of primary and secondary liver tumors. It is still unclear if the survival time can be extended through local ablative procedures. This prospective study shows operative actions, complications and long-term follow-up of 19 patients undergoing cryotherapy. METHODS: Between 1997 and 1998, 19 patients underwent cryotherapy due to a non-resectable malignant liver tumor (17 patients with metastases of a colon carcinoma, 2 patients with a hepatocellular carcinoma). Twelve patients (63.2%) received cryotherapy only and seven patients (36.8%) received a combination of resection and cryotherapy. The median follow-up period was 23 months. RESULTS: In a total of 59 liver tumors (18 were resected and 41 received cryotherapy), 12 had cryotherapy only, and 7 had a combination of cryotherapy and resection. The 30-day lethality was 0%, and the rate of major complications was 21%. After one year, 27.3% of the patients were still recurrence- free. The recurrence rate for all tumors treated was 58.8%. The median survival time for all patients was 21 months. The one- and three-year survival rates were 62. 5% and 15.8%, respectively. CONCLUSIONS: The mortality for cryotherapy is low, but there is a high rate of complications and long-term tumor control is not sufficient. If local ablative procedures of hepatic lesions are to be performed, not laparotomy but percutaneous, percutaneous thermoablation should be discussed as an alternative therapeutic measure. | Wolfgang Jungraithmayr Dieter Burger Manfred Olschewski Stefan Eggstein | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，4： | 26 |
| 2 | The 2007 WHO Classification of Tumours of the Central Nervous System显示文摘 | David N. Louis Hiroko Ohgaki Otmar D. Wiestler Webster K. Cavenee Peter C. Burger Anne Jouvet Bernd W. Scheithauer Paul Kleihues | 2007 | Acta Neuropathologica2007，，2： | 13 |
| 3 | 光伏逆变器-市场、技术和发展趋势显示文摘光伏阵列和逆变器的市场正在以高达40%的年平均增长率迅猛发展。2007年总的市场大约为2.5GW,而且在2007年年末的总装机容量将达到约10Gw。光伏逆变器将阵列输出的直流电流转化成交流电流,并且反馈回电网。逆变器拓扑结构有三种基本形式:带低频(50/60Hz)变压器的逆变器、带高频变压器的逆变器、无变压器的逆变器。无变压器的逆变器在欧洲市场上占主导地位,市场份额约为80%,在日本市场上占有接近50%的份额,而在美国由于国家标准的要求,只能使用带变压器的逆变器。无变压器的逆变器的效率高达98%。高效率的无变压器逆变器这是一个国际的发展趋势。随着技术发展,通过采用中点钳位拓扑(NPC)和新型电力半导体器件材料如碳化硅,将使得逆变器效率达到98.5%。 | 贺明智 冯轲 Bruno Burger Werner Roth | 2008 | 电力电子2008，，3： | 10 |
| 4 | 多形性黄色瘤型星形细胞瘤:自然病史和长期随访显示文摘作者回顾性研究74例多形性黄色瘤型星形细胞瘤(PXA)组织学问变特征和BRAFV600E突变的预后意义。患者平均诊断年龄21.5岁,包括31例儿童和43例成人,随访中位时间为7.6年。间变特征(PXA—AF)定义为核分裂指数≥5个/10HPF和(或)伴有坏死,共有33例。作者将其中60例进行免疫组化和(或)分子分析,发现其中39例BRAFV600E突变,且这39例IDH1(R132H)均为阴性。 | Ida C M Rodriguez F J Burger P C 李晓玲 王行富 | 2015 | 临床与实验病理学杂志2015，31，11： | 9 |
| 5 | 牛疱疹病毒Ⅳ型(DN-599株)DNA的限制性酶切位点图及重复序列分析显示文摘牛疱疹病毒Ⅳ型(BHV-4)DNA片段分别被重组到质粒pUC9或pBR322的EcoRI、Hind Ⅲ和BamHⅠ位点中,用光生物素(Photobiotin)标记这些重组质粒作为探针,分别与转移到硝基纤维素膜上的病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ片段进行杂交,根据杂交结果及克隆的BHV-4DNA片段的双酶切分析,画出了病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ位点图,井证明在病毒DNA的两末端含有多聚重复序列,左侧含12个重复单位,右侧含6个重复单位,两侧重复单位的排列方向相同,重复单位的大小为2.35kb。病毒DNA分子无任何异构体. | 童光志 Dieter Burger David T.Shen | 1990 | 病毒学报1990，6，2： | 8 |
| 6 | Contrasting responseS of hoverflies and wild bees to habitat structure and land use change in a tropical landscape (southern Yunnan, SW China)显示文摘到单一经营种植园的昆虫的反应主要在损坏自然森林区域的情况下继续了,并且是在生态学和保存生物学的一个突出、重要的问题,与授粉服务在全世界衰退了。在这研究,种类丰富和分发 hoverfly 并且野生的蜜蜂社区在一个变化被调查在南部的云南的热带风景,由不适的西南中国从 2008 ~ 2009 周期性地套住。种类从传统的陆地使用类型(自然森林,草地, shrubland 和稻田休闲) 被记录,并且从最近建立了不同年龄的橡胶种植园。Hoverflies (总数 53 种类) 在植被的年轻接连著的阶段是很普通的,包括稻田休闲和 shrubland。种类丰富在稻田休闲是最高的并且在森林里最低并且与非禾本草本植物种类和地面植被盖子的数字显示出一种高度重要的关系。相反,野生的蜜蜂(总数 44 种类) 的最高的丰富从自然森林地点被记录,它与留下的产地类型相比显示出一篇分离蜜蜂社区作文。在蜜蜂种类丰富和环境变量之间没有重要关系,包括不同植物生活表格,华盖的范围和地面植被的数字,植被的接连著的年龄和陆地使用打字。在风景规模,包括年轻橡胶种植园,开的陆地使用系统被假定增加 hoverflies 的种类丰富;然而,这可能减少野生的蜜蜂差异。由橡胶耕作的现在的陆地使用变化能被期望在本国的野生的蜜蜂社区上有否定影响。 | Ling-Zeng Meng Konrad Martin Jing-Xin Liu Frank Burger Jin Chen | 2012 | Insect Science2012，19，6： | 7 |
| 7 | Operation characteristics of AMS-02 loop heat pipe with bypass valve显示文摘Loop heat pipes (LHPs) were designed for the alpha magnetic spectrometer (AMS-02) to dissipate heat from the cryocoolers. A bypass valve is applied to the LHP to keep the cryocooler temperature above its limit ( 20°C) in cold environment. Extensive experiments were performed on operation characteristics of LHPs with the bypass valve for AMS-02 during thermal vacuum and thermal balance (TVTB) test. We found that the bypass valve can start up successfully in cold environment. With the bypass valve, the evaporator temperature is stable and can meet the requirement of the cryocooler. We analyzed three operating modes of the bypass valve. Set point temperature and regulation temperature shifts were observed and their relations with the bypass valve temperature were given. | WANG NaiHua Joseph BURGER LUO Feng CUI Zheng XIN GongMin DU WenJing SONG JiWei CHEN Yan CHENG Lin | 2011 | Science China(Technological Sciences)2011，54，7： | 6 |
| 8 | The HEPD particle detector of the CSES satellite mission for investigating seismo-associated perturbations of the Van Allen belts显示文摘CSES(China Seismo-Electromagnetic Satellite) is a mission developed by CNSA(Chinese National Space Administration) and ASI(Italian Space Agency), to investigate the near-Earth electromagnetic, plasma and particle environment, for studying the seismo-associated disturbances in the ionosphere-magnetosphere transition zone. The anthropogenic and electromagnetic noise,as well as the natural non-seismic electromagnetic emissions is mainly due to tropospheric activity. In particular, the mission aims to confirming the existence of possible temporal correlations between the occurrence of earthquakes for medium and strong magnitude and the observation in space of electromagnetic perturbations, plasma variations and precipitation of bursts with highenergy charged particles from the inner Van Allen belt. In this framework, the high energy particle detector(HEPD) of the CSES mission has been developed by the Italian LIMADOU Collaboration. HEPD is an advanced detector based on a tower of scintillators and a silicon tracker that provides good energy and angular resolution and a wide angular acceptance, for electrons of 3–100 Me V, protons of 30–200 Me V and light nuclei up to the oxygen. CSES satellite has been launched on February 2^(nd), 2018 from the Jiuquan Satellite Launch Center(China). | AMBROSI Giovanni BARTOCCI Simona BASARA Laurent BATTISTON Roberto BURGER William J. CARFORA Luca CASTELLINI Guido CIPOLLONE Piero CONTI Livio CONTIN Andrea DE DONATO Cinzia DE SANTIS Cristian FOLLEGA Francesco M. GUANDALINI Cristina IONICA Maria IUPPA Roberto LAURENTI Giuliano LAZZIZZERA Ignazio LOLLI Mauro MANEA Christian MARCELLI Laura MASCIANTONIO Giuseppe MERGE Matteo OSTERIA Giuseppe PACINI Lorenzo PALMA Francesco PALMONARI Federico PANICO Beatrice PATRIZII Laura PERFETTO Francesco PICOZZA Piergiorgio POZZATO Michele PUEL Matteo RASHEVSKAYA Irina RICCI Ester RICCI Marco RICCIARINI Sergio Bruno SCOTTI Valentina SOTGIU Alessando SPARVOLI Roberta SPATARO Bruno VITALE Vincenzo | 2018 | Science China(Technological Sciences)2018，61，5： | 6 |
| 9 | Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients.显示文摘 | Oblinger JL Pearl DK Boardman CL Saqr H Prior TW Scheithauer BW Jenkins RB Burger PC Yates AJ | 2006 | 中国神经肿瘤杂志2006，4，2： | 5 |
| 10 | Stochastic resonance whole body vibration increases perceived muscle relaxation but not cardiovascular activation:A randomized controlled trial显示文摘AIM To investigate the acute effects of stochastic resonance whole body vibration(SR-WBV), including muscle relaxation and cardiovascular activation.METHODS Sixty-four healthy students participated. The participants were randomly assigned to sham SR-WBV training at a low intensity(1.5 Hz) or a verum SR-WBV training at a higher intensity(5 Hz). Systolic blood pressure(SBP), diastolic blood pressure(DBP), heart rate(HR) and selfreported muscle relaxation were assessed before and immediately after SR-WBV.RESULTS Two factorial analyses of variance(ANOVA) showed a significant interaction between pre- vs post-SR-WBVmeasurements and SR-WBV conditions for muscle relaxation in the neck and back [F(1,55) = 3.35, P = 0.048, η2 = 0.07]. Muscle relaxation in the neck and back increased in verum SR-WBV, but not in sham SR-WBV. No significant changes between pre- and post-training levels of SBD, DBD and HR were observed either in sham or verum SR-WBV conditions. With verum SR-WBV, improved muscle relaxation was the most significant in participants who reported the experience of back, neck or shoulder pain more than once a month(P < 0.05).CONCLUSION A single session of SR-WBV increased muscle relaxation in young healthy individuals, while cardiovascular load was low. An increase in musculoskeletal relaxation in the neck and back is a potential mediator of pain reduction in preventive worksite SR-WBV trials. | Achim Elfering Christian Burger Volker Schade Lorenz Radlinger | 2016 | World Journal of Orthopedics2016，7，11： | 4 |
| 11 | Predictors of spine deformity progression in adolescent idiopathic scoliosis: A systematic review with meta-analysis显示文摘AIM: To evaluate published data on the predictors of progressive adolescent idiopathic scoliosis(AIS) in order to evaluate their efficacy and level of evidence. METHODS: Selection criteria:(1) study design: randomized controlled clinical trials, prospective cohort studies and case series, retrospective comparative and none comparative studies;(2) participants: adolescents with AIS aged from 10 to 20 years; and(3) treatment: observation, bracing, and other. Search method: Ovid MEDLINE, Embase, the Cochrane Library, Pub Medand patent data bases. All years through August 2014 were included. Data were collected that showed an association between the studied characteristics and the progression of AIS or the severity of the spine deformity. Odds ratio(OR), sensitivity, specificity, positive and negative predictive values were also collected. A metaanalysis was performed to evaluate the pooled OR and predictive values, if more than 1 study presented a result. The GRADE approach was applied to evaluate the level of evidence.RESULTS: The review included 25 studies. All studies showed statistically significant or borderline association between severity or progression of AIS with the following characteristics:(1) An increase of the Cobb angle or axial rotation during brace treatment;(2) decrease of the rib-vertebral angle at the apical level of the convex side during brace treatment;(3) initial Cobb angle severity(> 25o);(4) osteopenia;(5) patient age < 13 years at diagnosis;(6) premenarche status;(7) skeletal immaturity;(8) thoracic deformity;(9) brain stem vestibular dysfunction; and(10) multiple indices combining radiographic, demographic, and physiologic characteristics. Single nucleotide polymorphisms of the following genes:(1) calmodulin 1;(2) estrogen receptor 1;(3) tryptophan hydroxylase 1;(3) insulin-like growth factor 1;(5) neurotrophin 3;(6) interleukin-17 receptor C;(7) melatonin receptor 1B, and(8) Scoli Score test. Other predictors included:(1) impairment of melatonin signaling in osteoblasts and peripheral blood mononuclear cells(PBMC);(2) G-protein signaling dysfunction in PBMC; and(3) the level of platelet calmodulin. However, predictive values of all these findings were limited, and the levels of evidence were low. The pooled result of brace treatment outcomes demonstrated that around 27% of patents with AIS experienced exacerbation of the spine deformity during or after brace treatment, and 15% required surgical correction. However, the level of evidence is also low due to the limitations of the included studies.CONCLUSION: This review did not reveal any methods for the prediction of progression in AIS that could be recommended for clinical use as diagnostic criteria. | Andriy Noshchenko Lilian Hoffecker Emily M Lindley Evalina L Burger Christopher MJ Cain Vikas V Patel Andrew P Bradford | 2015 | World Journal of Orthopedics2015，6，7： | 4 |
| 12 | Design and experimental study of thermal control system for AMS cryocoolers显示文摘The Alpha Magnetic Spectrometer(AMS) is an instrument for the international scientific experiment,composed of six detectors and 650 micro-electronics.The objective of AMS experiment is to search for dark matter and anti-matter in space.In this paper,the thermal control system for AMS cryocoolers is designed,analyzed and experimentally studied.Using loop heat pipes(LHPs) as the main heat dissipation component,the thermal control system has sufficient heat dissipation capability to prevent the cryocoolers from over temperature(+40℃) in hot environment,meanwhile to ensure temperatures of the cryocoolers higher than their lower limit(-20℃) in cold environment.Experiment results show that the thermal control system for AMS cryocoolers functions stably satisfying design specification. | WANG NaiHua JOSEPH Burger CHENG Lin | 2013 | Chinese Science Bulletin2013，58，10： | 4 |
| 13 | 牛疱疹病毒Ⅳ型(DN-599株)DNA的分子克隆显示文摘从感染的MDBK(牛肾)细胞中直接抽提出牛疱疹病毒IV型(BHV-4)DNA。分别经限制性内切酶EcoRⅠ,HindⅢ或BamHI消化后,用鸟枪法和选择法将病毒DNA片段克隆到质粒pBR322和pUC9的相应位点中,构建了三组病毒DNA基因库。阳性克隆是用光生物素标记的病毒DNA和牛胸腺细胞DNA与各重组质粒DNA杂交而筛选的。总共克隆了病毒基因组的94%,其中用EcoRI克隆了83.4%,BamHI克隆了63.4%,HindIlI克隆了45%。 | 童光志 Dieter Burger David T Shen | 1990 | 病毒学杂志1990，4，4： | 4 |
| 14 | Big earth data analytics on Sentinel-1 and Landsat imagery in support to global human settlements mapping显示文摘Continuous global-scale mapping of human settlements in the service of international agreements calls for massive volume of multi-source,multi-temporal,and multi-scale earth observation data.In this paper,the latest developments in terms of processing big earth observation data for the purpose of improving the Global Human Settlement Layer(GHSL)data are presented.Two experiments with Sentinel-1 and Landsat data collections were run leveraging on the Joint Research Centre Earth Observation Data and Processing Platform.A comparative analysis of the results of built-up areas extraction from different remote sensing data and processing workflows shows how the information production supported by data-intensive computing infrastructure for optimization and multiple testing can improve the output information reliability and consistency within the GHSL scope.The paper presents the processing workflows and the results of the two main experiments,giving insights into the enhanced mapping capabilities gained by analyzing Sentinel-1 and Landsat data-sets,and the lessons learnt in terms of handling and processing big earth observation data. | Christina Corbane Martino Pesaresi Panagiotis Politis Vasileios Syrris Aneta JFlorczyk Pierre Soille Luca Maffenini Armin Burger Veselin Vasilev Dario Rodriguez Filip Sabo Lewis Dijkstra Thomas Kemper | 2017 | Big Earth Data2017，1，1： | 3 |
| 15 | 抑制素(一)显示文摘引言抑制素(Inhibin)是由双硫键连接的两个不同的亚单位,α(分子量20KD)与β(分子量3~15KD)所组成的糖蛋白,它抑制垂体促性腺激素,主要是抑制卵泡刺激素(FSH)的产生和(或)分泌。研究最广的是从牛、猪、羊、鼠和人样本纯化和克隆的分子量为31~32KD的抑制素。从卵巢卵泡液或颗粒细胞和支持细胞培养液中提取的,往往不同于31KD 型的是一些58KD 的分子量较高的抑制素,即具有较大的α44亚单位抑制素。β亚单位有两种类型,称为β_A 和β_a,其相应的抑制素二聚体称为抑制素 A 和抑制素 B。已证实β亚单位的二聚体具有刺激 FSH的活性,被称为激活素(Activin)。报据它是否由β_A 或β_a 组成的同种二聚体或由β_A | Henry G Burger 肖碧莲 | 1992 | 生殖医学杂志1992，1，1： | 3 |
| 16 | 牛传染性鼻气管炎病毒LA株DNA的分子克隆显示文摘本实验用鸟枪法和选择法将牛传染性鼻气管炎病毒(IBRV)的LA株DNA克隆到载体质粒pBR325,pBR322或pUC_9的HindⅢ位点中。经用光生物素标记的IBR DNA和牛胸腺细胞DNA与各重组质粒杂交筛选后,共得到10个病毒DNA的HindⅢ片段,分别是A,B,C,E,G,I,J,K,L和M,克隆的DNA占全病毒DNA的89.5%。 | 童光志 Dieter Burger | 1990 | 中国兽医科技1990，，7： | 3 |
| 17 | Comparative transcriptome analyses shed light on carotenoid production and plastid development in melon fruit显示文摘Carotenoids,such asβ-carotene,accumulate in chromoplasts of various fleshy fruits,awarding them with colors,aromas,and nutrients.The Orange(CmOr)gene controlsβ-carotene accumulation in melon fruit by posttranslationally enhancing carotenogenesis and repressingβ-carotene turnover in chromoplasts.Carotenoid isomerase(CRTISO)isomerizes yellow prolycopene into red lycopene,a prerequisite for further metabolism intoβ-carotene.We comparatively analyzed the developing fruit transcriptomes of orange-colored melon and its two isogenic EMS-induced mutants,low-β(Cmor)and yofi(Cmcrtiso).The Cmor mutation in low-βcaused a major transcriptomic change in the mature fruit.In contrast,the Cmcrtiso mutation in yofi significantly changed the transcriptome only in early fruit developmental stages.These findings indicate that melon fruit transcriptome is primarily altered by changes in carotenoid metabolic flux and plastid conversion,but minimally by carotenoid composition in the ripe fruit.Clustering of the differentially expressed genes into functional groups revealed an association between fruit carotenoid metabolic flux with the maintenance of the photosynthetic apparatus in fruit chloroplasts.Moreover,large numbers of thylakoid localized photosynthetic genes were differentially expressed in low-β.CmOR family proteins were found to physically interact with light-harvesting chlorophyll a–b binding proteins,suggesting a new role of CmOR for chloroplast maintenance in melon fruit.This study brings more insights into the cellular and metabolic processes associated with fruit carotenoid accumulation in melon fruit and reveals a new maintenance mechanism of the photosynthetic apparatus for plastid development. | Noam Chayut Hui Yuan Yuval Saar Yi Zheng Tianhu Sun Xuesong Zhou Anna Hermanns Elad Oren Adi Faigenboim Maixia Hui Zhangjun Fei Michael Mazourek Joseph Burger Yaakov Tadmor Li Li | 2021 | Horticulture Research2021，8，1： | 3 |
| 18 | 动态^(18)F-FDG PET定量分析用于骨病变鉴别诊断显示文摘目的 评价18F 脱氧葡萄糖 (FDG)PET在骨骼病变中的诊断价值。方法 研究对象为40例原发性骨骼病变患者。所有患者在注射示踪剂后立即开始动态PET采集 ,持续 6 0min。对动态PET图像进行半定量分析 ,分别计算平均和最大标准摄取值 (SUVaver和SUVmax) ,病灶SUV/肌肉SUV比值 (T/M) ,病灶 6 0minSUV/ 30minSUV比值 (SUVaver 60 /3 0min和SUVmax 60 /3 0min)等。采用Patlak作图分析法对动态图像数据进行拟合计算 ,得出摄入常数 (Ki) ,计算FDG代谢率 (MRFDG)。根据接受器工作特性曲线 (ROC)确定各定量指标的诊断阈值 ,并比较其鉴别良恶性病变的灵敏度和特异性。结果 经病理检查证实恶性病变 2 1例 ,良性病变 19例。恶性病变的MRFDG和SUV值高于良性病变 ,但各种指标的数值分布均存在交叉重叠。SUVaver与MRFDG呈正相关 (r=0 6 7)。以SUV值≥ 1 8作为阈值时 ,鉴别良恶性病变的灵敏度和特异性分别为 85 0 %和 82 4% ,以MRFDG(1 1)为阈值时的灵敏度 (82 4% )与SUV相近 ,而特异性 (92 9% )较高。同时采用SUV(1 8)和SUVaver 60 /3 0min(1 1)作为鉴别标准时 ,较之单独采用SUV特异性可改善为 93 3% ,灵敏度略有降低 (81 3% )。结论 骨骼良恶性病变之间存在葡萄糖代谢率差异。单用静态FDGPET获取SUV值不能很好鉴? | 吴华 Antonia Dimitrakopoulou-Strauss Thomas O-Heichel Burkhard Lehner Ludger Bernd Volker Ewerbeck Cyrill Burger Ludwig G Strauss | 2002 | 中华核医学杂志2002，22，2： | 3 |
| 19 | 阿尔法磁谱仪低温冷却器热控制系统设计及实验显示文摘阿尔法磁谱仪是国际空间站上的大型物理科学实验仪器,包含6组精密探仪器和650个微电子处理器.主要目的是探测暗物质和反物质的存在.对阿尔法磁谱仪低温冷却器热控制系统进行了设计、分析和实验研究.采用环路热管作为主要散热元件,既能保证在热态环境下,热系统具有足够的散热能力,低温冷却器不超温(+40℃);又能保证在冷态环境下,低温冷却器温度高于运行温度下限(20℃).结果表明,低温冷却器热控制系统运行稳定,达到了设计要求. | 王乃华 Joseph Burger 程林 | 2013 | 科学通报2013，58，5： | 2 |
| 20 | Evolution of gastroenterology training显示文摘There have been rapid developments in gastroenterology(GE)over the last decade.Up until the late 1980s,GE-training was incorporated in Internal Medicine training.The introduction of endoscopy has necessitated the need for additional training.Around the world different national boards have developed their own curricula which will be discussed in this paper. Emphasis will be placed on the curriculum recently introduced in The Netherlands.The internal medicine component has become a two-year requirement (Common Trunk)and the duration of training in GE has been extended to four years.Because of the growing complexity of GE,there are now four subspecialties:Interventional Endoscopy,Neuromotility, Oncology and Hepatology that trainees can choose from.These subspecialties each have predefined specific requirements.The World Gastroenterology Organization has drawn up a standard curriculum which can be of help to the boards in different countries. The curriculum emphasizes the knowledge and skill components.The curriculum also defines the training recommendations,the requirements of training facilities and competence evaluation of fellows and facilities,while less is said about research,finance and the number of gastroenterologists required.In the coming decades the curriculum will need to be revised continuously.Personalization of the curriculum will be the next challenge for the years to come. | Hanna Telleman Trevlyn Felicity Burger Chris Jacob Johan Mulder | 2009 | World Journal of Gastroenterology2009，15，15： | 2 |
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