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1A method to estimate concentrations of surface-level particulate matter using satellite-based aerosol optical thickness显示文摘We propose a new method to estimate surface-level particulate matter(PM)concentrations by using satellite-retrieved Aerosol Optical Thickness(AOT).This method considers the distribution and variation of Planetary Boundary Layer(PBL)height and relative humidity(RH)at the regional scale.The method estimates surface-level particulate matter concentrations using the data simulated by an atmospheric boundary layer model RAMS and satellite-retrieved AOT.By incorporation MODIS AOT,PBL height and RH simulated by RAMS,this method is applied to estimate the surface-level PM 2.5 concentrations in North China region.The result is evaluated by using 16 ground-based observations deployed in the research region,and the result shows a good agreement between estimated PM 2.5 concentrations and observations,and the coefficient of determination R2 is 0.61 between the estimated PM 2.5 concentrations and the observations.In addition,surface-level PM 2.5 concentrations are also estimated by using MODIS AOT,ground-based LIDAR observations and RH measurements.A comparison between the two estimated PM 2.5 concentrations shows that the new method proposed in this paper is better than the traditional method.The coefficient of determination R2 is improved from 0.32 to 0.62.TAO JinHua ZHANG MeiGen CHEN LiangFu WANG ZiFeng SU Lin GE Cui HAN Xiao ZOU MingMin 2013Science China Earth Sciences2013,56,8:20
2Influence of mesoscale eddies on primary production in the South China Sea during spring inter-monsoon period显示文摘Mesoscale eddies have been suggested to have an impact on biological carbon fixation in the South China Sea(SCS). However, their overall contribution to primary production during the spring inter-monsoon period is still unknown. Based on large-scale biological and environmental in situ observations and synchronous remote sensing data, the distribution patterns of phytoplankton biomass and the primary production, and the role of mesoscale eddies in regulating primary production in different eddy-controlled waters were investigated. The results suggested that the surface chlorophyll a concentrations and water column integrated primary production(IPP) are significantly higher in cyclonic eddies and lower in the anticyclonic eddies as compared to that in non-eddy waters. Although eddies could affect various environmental factors, such as nutrients, temperature and light availability, nutrient supply is suggested to be the most important one through which mesoscale eddies regulated the distribution patterns of phytoplankton biomass and primary production. The estimated IPP in cyclonic and anticyclonic eddies are about 29.5% higher and 16.6% lower than the total average in the whole study area, respectively, indicating that the promotion effect of mesoscale cold eddies on the primary production was much stronger than the inhibition effect of the warm eddies per unit area. Overall, mesoscale eddies are crucial physical processes that affect the biological carbon fixation and the distribution pattern of primary production in the SCS open sea, especially during the spring inter-monsoon period.HU Zifeng TAN Yehui SONG Xingyu ZHOU Linbin LIAN Xiping HUANG Liangmin HE Yinghui 2014Acta Oceanologica Sinica2014,33,3:16
3miR-221/222 activate the Wnt/β-catenin signaling to promote triple-negative breast cancer显示文摘Sanhong Liu Zifeng Wang Zukai Liu Shuo Shi Zhaoran Zhang Jiawei Zhang Haifan Lin 2018Journal of Molecular Cell Biology2018,10,4:16
4The Notch signaling pathway in retinal dysplasia and retina vascular homeostasis显示文摘The retina is one of the most essential elements of vision pathway in vertebrate. The dysplasia of retina cause congenital blindness or vision disability in individuals, and the misbalance in adult retinal vascular homeostasis leads to neovascularization-associated diseases in adults, such as diabetic retinopathy or age-related macular degeneration. Many developmental signaling pathways are involved in the process of retinal development and vascular homeostasis. Among them, Notch signaling pathway has long been studied, and Notch signaling-interfered mouse models show both neural retina dysplasia and vascular abnormality. In this review, we discuss the roles of Notch signaling in the maintenance of retinal progenitor cells, specification of retinal neurons and glial cells, and the sustaining of retina vascular homeostasis, especially from the aspects of conditional knockout mouse models. The potential of Notch signal manipulation may provide a powerful cell fate- and neovascularization-controlling tool that could have important applications in treatment of retinal diseases.Minhua Zheng Zifeng Zhang Xingcheng Zhao Yuqiang Ding Hua Han 2010Journal of Genetics and Genomics2010,37,9:13
5Erucic acid from Isatis indigotica Fort. suppresses influenza A virus replication and inflammation in vitro and in vivo through modulation of NF-kB and p38 MAPK pathway显示文摘Isatis indigotica Fort.(Ban-Lan-Gen)is an herbal medicine prescribed for influenza treatment.However,its active components and mode of action remain mostly unknown.In the present study,erucic acid was isolated from Isatis indigotica Fort.,and subsequently its underlying mechanism against influenza A virus(IAV)infection was investigated in vitro and in vivo.Our results demonstrated that erucic acid exhibited broad-spectrum antiviral activity against IAV resulting from reduction of viral polymerase transcription activity.Erucic acid was found to exert inhibitory effects on IAV or viral(v)RNA-induced pro-inflam-matory mediators as well as interferons(IFNs).The molecular mechanism by which erucic acid with antiviral and anti-inflammatory properties was attributed to inactivation of NF-kB and p38 MAPK signaling.Furthermore,the NF-kB and p38 MAPK inhibitory effect of erucic acid led to diminishing the transcriptional activity of interferon-stimulated gene factor 3(ISGF-3),and thereby reducing IAV-triggered pro-inflammatory response amplification in IFN-β-sensitized cells.Additionally,IAV-or vRNA-triggered apoptosis of alveolar epithelial A549 cells was prevented by erucic acid.In vivo,erucic acid administration consistently displayed decreased lung viral load and viral antigens expression.Meanwhile,erucic acid markedly reduced CD8+cytotoxic T lymphocyte(CTL)recruitment,pro-apoptotic signaling,hyperactivity of multiple signaling pathways,and exacerbated immune inflammation in the lung,which resulted in decreased lung injury and mortality in mice with a mouse-adapted A/FM/1/47-MA(H1N1)strain infection.Our findings provided a mechanistic basis for the action of erucic acid against IAV-mediated inflammation and injury,suggesting that erucic acid may have a therapeutic potential in the treatment of influenza.Xiaoli Liang Yuan Huang Xiping Pan Yanbing Hao Xiaowei Chen Haiming Jiang Jing Li Beixian Zhou Zifeng Yang 2020Journal of Pharmaceutical Analysis2020,10,2:10
6Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype.Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu 2021Cell Research2021,31,3:9
7Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world.Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong 2022Science China(Life Sciences)2022,65,9:9
8Local Gabor Dominant Direction Pattern for Face Recognition显示文摘We propose a novel face image representation – Local gabor dominant direction pattern(LGDDP)for face recognition. The face image is convolved with the Gabor filters, resulting in multiple response images of different orientations and scales. The response images' each pixel is encoded by the LGDDP descriptor from the pixel's dominant neighboring one or two pixels. The image formed by the LGDDP descriptor is partitioned into multiple regions and the histogram is extracted from each region. All the histograms are concatenated into the spatial histogram.The nearest neighbor classifier and the weighted intersection histogram similarity measure are used for face image classification. The advantage of the proposed LGDDP method lies in the high recognition rate performance and the low computational complexity. Extensive experiments are performed on FERET face image database and the experimental results verify the LGDDP's effectiveness by comparing LGDDP with other well-known published face recognition methods.LIU Jun JING Xiaojun SUN Songlin LIAN Zifeng 2015Chinese Journal of Electronics2015,24,2:8
9In Situ Synthesis of NaY Zeolite with Coal-Based Kaolin显示文摘NaY zeolites were in-situ synthesized from coal-based kaolin via the hydrothermal method.The effects of various factors on the structure of the samples were extensively investigated. The sampleswere characterized by N2 adsorption, XRD, IR and DTG-DTA methods, and the results show that thecrystallization temperature and amount of added water play an important role in the formation of the zeo-lite structure. The 4A and P zeolites are the competitive phase present in the resulting product. However,NaY zeolites with a higher relative crystallinity, excluding impure crystals and the well hydrothermal sta-bility, can be synthesized from coal-based kaolin. These zeolites possess a larger surface area and a narrowpore size distribution, and this means that optimization of this process might result in a commercial routeto synthesize NaY zeolites from coal-based kaolin.Xinmei Liu, Zifeng Yan, Huaiping Wang, Yantuo LuoState Key Laboratory for Heavy Oil Processing, Key Laboratory of Catalysis, CNPC, University of Petroleum, Dongying 257061, China 2003Journal of Natural Gas Chemistry2003,12,1:8
10Factors affecting genomic selection revealed by empirical evidence in maize显示文摘Genomic selection(GS) as a promising molecular breeding strategy has been widely implemented and evaluated for plant breeding, because it has remarkable superiority in enhancing genetic gain, reducing breeding time and expenditure, and accelerating the breeding process. In this study the factors affecting prediction accuracy(rMG) in GS were evaluated systematically, using six agronomic traits(plant height, ear height, ear length, ear diameter,grain yield per plant and hundred-kernel weight) evaluated in one natural and two biparental populations. The factors examined included marker density, population size, heritability,statistical model, population relationships and the ratio of population size between the training and testing sets, the last being revealed by resampling individuals in different proportions from a population. Prediction accuracy continuously increased as marker density and population size increased and was positively correlated with heritability; rMGshowed a slight gain when the training set increased to three times as large as the testing set. Low predictive performance between unrelated populations could be attributed to different allele frequencies, and predictive ability and prediction accuracy could be improved by including more related lines in the training population. Among the seven statistical models examined, including ridge regression best linear unbiased prediction(RR-BLUP), genomic BLUP(GBLUP), Bayes A, Bayes B, Bayes C, Bayesian least absolute shrinkage and selection operator(Bayesian LASSO), and reproducing kernel Hilbert space(RKHS), the RKHS and additive-dominance model(Add + Dom model) showed credible ability for capturing non-additive effects, particularly for complex traits with low heritability. Empirical evidence generated in this study for GS-relevant factors will help plant breeders to develop GS-assisted breeding strategies for more efficient development of varieties.Xiaogang Liu Hongwu Wang Hui Wang Zifeng Guo Xiaojie Xu Jiacheng Liu Shanhong Wang Wen-Xue Li Cheng Zou Boddupalli M.Prasanna Michael S.Olsen Changling Huang Yunbi Xu 2018The Crop Journal2018,6,4:8
11Recent Progress of MXene-Based Nanomaterials in Flexible Energy Storage and Electronic Devices显示文摘The increasing demands for wearable electronics have stimulated the rapid development of flexible energy storage devices.MXenes are considered as promising flexible electrodes due to the ultrahigh volumetric specific capacitance,metallic conductivity,superior hydrophily,and rich surface chemistry.Qi Yang Yukun Wang Xinliang Li Hongfei Li Zifeng Wang Zijie Tang Longtao Ma Funian Mo Chunyi Zhi 2018Energy & Environmental Materials2018,1,4:8
12Synthesis of Li_4Ti_5O_(12) nanostructural anode materials with high charge–discharge capability显示文摘This study demonstrates a facile and efficient hydrothermal method to prepare spindle titanate(Li4Ti5O12 denoted as LTO)and/or carbon-LTO nanocomposites(CLTO),in which the LTO or C-LTO microspheres have diameters of a few micrometers,composed of numerous nanosheets with thickness of*30 nm and edge length of hundreds of nanometers.The morphology and size control of these nanoparticles could be achieved by varying experimental parameters including concentration of titanium butoxide,lithium hydroxide,and cetyltrimethylammonium bromide,as well as reaction temperature and time.These micro-nanostructures were characterized by several advanced techniques,such as transmission electron microscopy,scanning electron microscopy,X-ray diffraction,energy dispersive spectroscopic analysis,surface area,and electrochemical measurements.The LTO and C-LTO microstructures were examined in the charge–discharge capacity at a rate of 50 C,as well as the stability after 100 cycles at a rate of 10 C.The excellent capability may be attributed to good conductivity,large surface area,and stable assembly structure of such micro-nanostructures,which could be explored as a promising anode material for lithium-ion batteries.Ru Wen Jeffrey Yue Zifeng Ma Wuming Chen Xuchuan Jiang Aibing Yu 2014Chinese Science Bulletin2014,59,18:8
13Evolutionary approach for spatial architecture layout design enhanced by an agent-based topology finding system显示文摘Zifeng Guo Biao Li 2017Frontiers of Architectural Research2017,6,1:7
14DropConnect Regularization Method with Sparsity Constraint for Neural Networks显示文摘Drop Connect is a recently introduced algorithm to prevent the co-adaptation of feature detectors.Compared to Dropout, Drop Connect gains state-of-the-art results on several image recognition benchmarks. Motivated by the success of Drop Connect, we extended this algorithm with the ability of sparse feature selection. In Drop Connect algorithm, the dropping masks of weights are generated using Bernoulli gating variables that are independent of the weights and activations. We introduce a new strategy to generate masks depending on the outputs of previous layer. Using this method, neurons which are promising to produce sparser features will be assigned a bigger possibility to keep active in the forward and backward propagations. We then evaluate such sparsity constrained Drop Connect on MNIST and CIFAR datasets in comparison with ordinary Drop Connect and Dropout method. The results show that our new method improves the sparsity of features significantly, while not degrading the precision.LIAN Zifeng JING Xiaojun WANG Xiaohan HUANG Hai TAN Youheng CUI Yuanhao 2016Chinese Journal of Electronics2016,25,1:6
15A New Approach of Feature Selection for Text Categorization显示文摘This paper proposes a new approach of feature selection based on the independent measure between features for text categorization. A fundamental hypothesis that occurrence of the terms in documents is independent of each other, widely used in the probabilistic models for text categorization (TC), is discussed. However, the basic hypothesis is incomplete for independence of feature set. From the view of feature selection, a new independent measure between features is designed, by which a feature selection algorithm is given to obtain a feature subset. The selected subset is high in relevance with category and strong in independence between features, satisfies the basic hypothesis at maximum degree. Compared with other traditional feature selection method in TC (which is only taken into the relevance account), the performance of feature subset selected by our method is prior to others with experiments on the benchmark dataset of 20 Newsgroups.CUI Zifeng XU Baowen ZHANG Weifeng XU Junling 2006Wuhan University Journal of Natural Sciences2006,11,5:6
16Hierarchical peony-like FeCo-NC with conductive network and highly active sites as efficient electrocatalyst for rechargeable Zn-air battery显示文摘Carbon materials featuring hierarchical pores and atomically dispersed metal sites are promising catalysts for energy storage and conversion applications.Herein,we developed a facile strategy to construct functional carbon materials with a fluffy peony-like structure and dense binary FeCo-Nx active sites(termed as f-FeCo-CNT).By regulating the metal content in precursors,a three-dimensional(3D)interconnected conductive carbon nanotubes network was in-situ formed throughout the atomically dispersed FeCo-NC matrix during pyrolysis.Taking advantage of rich pore hierarchy and co-existence of highly active FeCo-Nx sites and beneficial FeCo alloy nanoparticles,the f-FeCo-CNT material exhibited excellent bifunctional performance towards oxygen reduction reaction/oxygen evolution reactions(ORR/OER)with respect to the atomically dispersed FeCo-NC(SA-f-FeCo-NC)and commercial Pt/C+Ru02 mixture,surpassing the SA-f-FeCo-NC with a 20 mV higher ORR half-wave potential and a 100 mV lower OER overpotential(at 10.0 mA/cm^2).Remarkably,the f-FeCo-CNT-assembled Zn-air battery(ZAB)possessed a maximum specific power of 195.8 mW/cm^2,excellent rate capability,and very good cycling stability at large current density of 20.0 mA/cm^2.This work provides a facile and feasible synthetic strategy of constructing low-cost cathode materials with excellent comprehensive ZAB performance.Yiyan Wang Anuj Kumar Mang Ma Yin Jia Yu Wang Ying Zhang Guoxin Zhang Xiaoming Sun Zifeng Yan 2020Nano Research2020,13,4:5
17Application of New Heavy Metals Resistant Porous Binder Material Used in Fluid Catalytic Cracking Reaction显示文摘A novel porous binder was obtained from acid-treated kaolin. This new binder possessed abundant meso/macropores, good hydrothermal stability and heavy metal resistance. The prepared catalyst using new binder featured low attrition index and large pore volume. The catalysts were contaminated with Ni, V, and tested in a fixed-fluidized bed reactor unit. In comparison with the reference sample, the oil conversion achieved by the above-mentioned catalyst increased by 3.50 percentage points, and heavy oil yield decreased by 2.86 percentage points, while the total liquid yield and light oil yield increased by 2.82 percentage points and 0.79 percentage points, respectively. The perfect pore structure, good hydrothermal stability and heavy metal resistant performance of new binder were the possible causes leading to its outstanding performance.Zhang Zhongdong Liu Zhaoyong Yan Zifeng Gao Xionghou Zhang Haitao Wang Zhifeng 2014China Petroleum Processing & Petrochemical Technology2014,16,1:5
18Tracking characteristics of tracer particles for PIV measurements in supersonic flows显示文摘The tracking characteristics of tracer particles for particle image velocimetry(PIV) measurements in supersonic flows were investigated.The experimental tests were conducted at Mach number 4 in Multi-Mach Wind Tunnel(MMWT) of Shanghai Jiao Tong University.The motion of tracer particles carried by the supersonic flow across Shockwaves was theoretically modelled,and then their aerodynamic characteristics with compressibility and rarefaction effects were evaluated.According to the proposed selection criterion of tracer particles,the PIV measured results clearly identified that the Shockwave amplitude is in good agreement with theory and Schlieren visualizations.For the tracer particles in nanoscales,their effective aerodynamic sizes in the diagnostic zone can be faithfully estimated to characterize the tracking capability and dispersity performance based on their relaxation motion across oblique Shockwaves.On the other hand,the seeding system enabled the tracer particles well-controlled and repeatable dispersity against the storage and humidity.Chen Fang Liu Hong Yang Zifeng Hu Hui 2017Chinese Journal of Aeronautics2017,30,2:5
19Hierarchically porous carbon/red phosphorus composite for high-capacity sodium-ion battery anode显示文摘Red phosphorus has received remarkable attention as a promising anode material for sodium ion batteries(NIBs) due to its high theoretical capacity. However, its practical application has been impeded by its intrinsic low electronic conductivity and large volume variations during sodiation/desodiation process. Here, we design a composite to confine nanosized red phosphorus into the hierarchically porous carbon(HPC) walls by a vaporization-condensation strategy. The mass loading of P in the HPC/P composite is optimized to deliver a reversible specific capacity of 2,202 m Ah/gpbased on the mass of red P(836 m Ah/gcompositebased on the total composite mass), a high capacity retention over 77% after100 cycles, and excellent rate performance of 929 m Ah/gpat 2 C. The hierarchical porous carbon serves as the conductive networks, downsize the red phosphorus to nanoscale, and provide free space to accommodate the large volume expansions. The suppressed mechanical failure of the red phosphorus also enhances the stability of solid-electrolyte interface(SEI) layer, which is confirmed by the microscopy and impedance spectroscopy after the cycling tests. Our studies provide a feasible approach for potentially viable high-capacity NIB anode.Meng Li Na Feng Mengmeng Liu Zifeng Cong Jiangman Sun Chunhua Du Quanbin Liu Xiong Pu Weiguo Hu 2018Science Bulletin2018,63,15:5
20An experimental investigation on the trailing edge cooling of turbine blades显示文摘An experimental study was conducted to quantify the flow characteristics of the wall jets pertinent to trailing edge cooling of turbine blades.A high-resolution stereoscopic particle image velocimetry(PIV)system was used to conduct detailed flow field measurements to quantitatively visualize the evolution of the unsteady vortices and turbulent flow structures in the cooling wall jet streams and to quantify the dynamic mixing process between the cooling jet stream and the mainstream flows.The detailed flow field measurements were correlated with the adiabatic cooling effectiveness maps measured by using pressure sensitive paint(PSP)technique to elucidate underlying physics in order to explore/optimize design paradigms for improved cooling effectiveness to protect the critical portions of turbine blades from harsh environments.Zifeng Yang Hui Hun 2012Propulsion and Power Research2012,1,1:5
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