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| 1 | Intrusion Detection for Wireless Mesh Networks using Finite State Machine显示文摘 | Yi Ping Wu Yue Liu Ning Wang Zhiyang | 2010 | China Communications2010，7，5： | 5 |
| 2 | Genome architecture and tetrasomic inheritance of autotetraploid potato显示文摘Potato(Solanum tuberosum)is the most consumed non-cereal food crop.Most commercial potato cultivars are autotetraploids with highly heterozygous genomes,severely hampering genetic analyses and improvement.By leveraging the state-of-the-art sequencing technologies and polyploid graph binning,we achieved a chromosome-scale,haplotype-resolved genome assembly of a cultivated potato,Cooperation-88(C88).lntra-haplotype comparative analyses revealed extensive sequence and expression differences in this tetraploid genome.We identified haplotype-specific pericentromeres on chromosomes,suggesting a distinct evolutionary trajectory of potato homologous centromeres.Furthermore,we detected double reduction events that are unevenly distributed on haplotypes in 1021 of 1034 selfing progeny,a feature of autopolyploid inheritance.By distinguishing maternal and paternal haplotype sets in C88,we simulated the origin of heterosis in cultivated tetraploid with a survey of 3110 tetra-allelic loci with deleterious mutations,which were masked in the heterozygous condition bytwo parents.This study provides insights into the genomic architecture of autopolyploids and will guide their breeding. | Zhigui Bao Canhui Li Guangcun Li Pei Wang Zhen Peng Lin Cheng Hongbo Li Zhiyang Zhang Yuying Li Wu Huang Mingwang Ye Daofeng Dong Zhukuan Cheng Peter VanderZaag Evert Jacobsen Christian W.B.Bachem Suomeng Dong Chunzhi Zhang Sanwen Huang Qian Zhou | 2022 | Molecular Plant2022，15，7： | 4 |
| 3 | Hierarchical carbon nanocages as high-rate anodes for Li-and Na-ion batteries显示文摘新奇的层次碳 nanocages (hCNCs ) 为 Li 离子和 Na 离子电池作为高率的阳极被建议。为 hCNCs 的多孔的网络的唯一的结构极大地赞成电解质穿入,离子散开,电子传导,和结构的稳定性,导致高率能力和优秀 cyclability。为锂存储,相应电极存储 970 mAh 的一个稳定的可逆能力吗? | Zhiyang Lyu Lijun Yang Dan Xu Jin Zhao Hongwei Lai Yufei Jiang Qiang Wu Yi Li Xizhang Wang Zheng Hu | 2015 | Nano Research2015，8，11： | 3 |
| 4 | Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats显示文摘Cell-based transplantation strategies possess great potential for spinal cord injury(SCI)repair.Basic fibroblast growth factor(bFGF)has been reported to have multiple neuro-promoting effects on developing and adult nervous system of mammals and considered a promising therapy for nerve injury following SCI.Human dental pulp stem cells(DPSCs)are abundant stem cells with low immune rejection,which can be considered for cell replacement therapy.The purpose of this study was to investigate the roles of DPSCs which express bFGF under the regulation of five hypoxia-responsive elements(5HRE)using an adeno-associated virus(AAV-5HRE-bFGF-DPSCs)in SCI repairing model.In this study,DPSCs were revealed to differentiate into CD13^(+)pericytes and up-regulate N-cadherin expression to promote the re-attachment of CD13^(+)pericytes to vascular endothelial cells.The re-attachment of CD13^(+)pericytes to vascular endothelial cells subsequently increased the flow rate of blood in microvessels via the contraction of protuberance.As a result,increased numbers of red blood cells carried more oxygen to the damaged area and the local hypoxia microenvironment in SCI was improved.Thus,this study represents a step forward towards the potential use of AAV-5HRE-bFGF-DPSCs in SCI treatment in clinic. | Sipin Zhu Yibo Ying Yan He Xingxing Zhong Jiahui Ye Zhiyang Huang Min Chen Qiuji Wu Yifan Zhang Ziyue Xiang Yurong Tu Weiyang Ying Jian Xiao Xiaokun Li Qingsong Ye Zhouguang Wang | 2021 | Bioactive Materials2021，6，8： | 2 |
| 5 | A shear-thinning,ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis显示文摘Spinal cord injury(SCI)is a serious clinical disease.Due to the deformability and fragility of the spinal cord,overly rigid hydrogels cannot be used to treat SCI.Hence,we used TPA and Laponite to develop a hydrogel with shear-thinning ability.This hydrogel exhibits good deformation,allowing it to match the physical properties of the spinal cord;additionally,this hydrogel scavenges ROS well,allowing it to inhibit the lipid peroxidation caused by ferroptosis.According to the in vivo studies,the TPA@Laponite hydrogel could synergistically inhibit ferroptosis by improving vascular function and regulating iron metabolism.In addition,dental pulp stem cells(DPSCs)were introduced into the TPA@Laponite hydrogel to regulate the ratios of excitatory and inhibitory synapses.It was shown that this combination biomaterial effectively reduced muscle spasms and promoted recovery from SCI. | Yibo Ying Zhiyang Huang Yurong Tu Qiuji Wu Zhaoyu Li Yifan Zhang Huilei Yu Annian Zeng Hanzhi Huang Jiahui Ye Weiyang Ying Min Chen Zhiyi Feng Ziyue Xiang Qingsong Ye Sipin Zhu Zhouguang Wang | 2023 | Bioactive Materials2023，，4： | 2 |
| 6 | Development of retinol-binding protein 4 immunocolloidal gold fast test strip using high-sensitivity monoclonal antibodies generated by DNA immunization显示文摘DNA 免疫是为高亲密关系的 monoclonal 抗体产生的一个有效方法。这里,我们对松香油绑定蛋白质 4 描述几高质量的 monoclonal 抗体(mAbs ) 的产生(RBP4 ) ,为肾反常和机能障碍的一个重要标记,与 DNA 的一个联合方法, priming 和蛋白质增加。产生的 mAbs 能与高敏感并且用这些 mAbs 绑在 RBP4,一块 immunocolloidal 金牌快测试长带被构造。长带能交上结果 < 5 min 并且与大约 1 ng/ml 的察觉限制是很敏感的。小规模的临床的测试表明这脱衣的结果根据在市场上当前可得到的一个标记酶的 immunosorbent 试金工具包的好。因而,它能为在诊所的更方便、更快的 RBP4 决心是有用的。 | Chao Bian Fang Zhang Feng Wang Zhiyang Ling Min Luo Hongqiang Wu Yizhuo Sun Junhui Li B ingnan Li Jingyan Zhu Linna Tang Yanyan Zhou Qunfang Shi Yongyong Ji Lin Tian Guomei Lin Yu Fan Niansong Wang Bing Sun | 2010 | Acta Biochimica et Biophysica Sinica2010，42，12： | 2 |
| 7 | Protective humoral immunity in SARS-CoV-2 infected pediatric patients显示文摘After the rapid spread of SARS-CoV-2 in Wuhan,China,at the beginning of 2020,about 1.5 million confirmed cases and over 80,000 deaths have been reported around 200 countries and territories all over the world and the number continues to increase.However,we still have limited knowledge of this new coronavirus,especially the interaction between SARS-CoV-2 and our immune system. | Yaguang Zhang Jin Xu Ran Jia Chunyan Yi Wangpeng Gu Pengcheng Liu Xinran Dong Hao Zhou Bo Shang Shipeng Cheng Xiaoyu Sun Jing Ye Xuezhen Li Jia Zhang Zhiyang Ling Liyan Ma Bingbing Wu Mei Zeng Wenhao Zhou Bing Sun | 2020 | Cellular & Molecular Immunology2020，17，7： | 2 |
| 8 | Versatile subtypes of pericytes and their roles in spinal cord injury repair,bone development and repair显示文摘Vascular regeneration is a challenging topic in tissue repair. As one of the important components of the neurovascular unit(NVU),pericytes play an essential role in the maintenance of the vascular network of the spinal cord. To date, subtypes of pericytes have been identified by various markers, namely the PDGFR-β, Desmin, CD146, and NG2, each of which is involved with spinal cord injury(SCI) repair. In addition, pericytes may act as a stem cell source that is important for bone development and regeneration, whilst specific subtypes of pericyte could facilitate bone fracture and defect repair. One of the major challenges of pericyte biology is to determine the specific markers that would clearly distinguish the different subtypes of pericytes, and to develop efficient approaches to isolate and propagate pericytes. In this review, we discuss the biology and roles of pericytes, their markers for identification, and cell differentiation capacity with a focus on the potential application in the treatment of SCI and bone diseases in orthopedics. | Sipin Zhu Min Chen Yibo Ying Qiuji Wu Zhiyang Huang Wenfei Ni Xiangyang Wang Huazi Xu Samuel Bennett Jian Xiao Jiake Xu | 2022 | Bone Research2022，10，2： | 2 |
| 9 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 10 | Angular spectrum transfer function of photon scanning tunnel microscopy显示文摘 | Zhiyang Li Wu Liu Chuanyun Xiao | 1996 | CCAST WL Workship Series1996，64，： | 1 |
| 11 | Investigation of flow unsteadiness in a highly-loaded compressor cascade using a dynamic mode decomposition method显示文摘Unsteady flow in the hub endwall region has long been a hot topic in the turbomachinery community.However important it is to the performance of the whole engine,the coherent unsteady flow phenomena are still not well understood.In this paper,the complex flow field in the hub endwall of a cantilevered compressor cascade has been investigated through numerical approach.The predicted results were validated by experimental data.To highlight the dominant flow structures among irregular and chaotic motions of various vortices,a Dynamic Mode Decomposition(DMD)method was utilized.The results show that there exist three dominant periodic flow structures:the oscillation of the leakage vortex,a circumferential migration of a Breakdown Induced Vortex(BIV)and the fluctuation of the passage vortex.These three coherent structures all together form a self-sustained closed loop which accounts for the flow unsteadiness of the studied cascade.During this process,the BIV plays a key role in inducing the flow unsteadiness.Only if the BIV is strong enough to affect the passage vortex,the flow unsteadiness occurs.This study expands current knowledge base of flow unsteadiness in a compressor environment,and shows the efficacy of the DMD method for revealing the origin of flow unsteadiness. | Guangyao AN Yanhui WU Jinhua LANG Zhiyang CHEN Xiaobing ZHOU | 2022 | Chinese Journal of Aeronautics2022，35，5： | 1 |
| 12 | Angular spectrum transfer function of photon scanning tunnel microscopy 显示文摘 | Zhiyang Li Wu Liu Chuanyun Xiao | 1996 | CCAST-WL Workship Series1996，64，： | 1 |
| 13 | A Virtual Network Mapping Algorithm Based on Time显示文摘As one of the challenges for network virtualization, virtual network embedding which maps Virtual network(VN) to the substrate network and allocates resources according to the requirements of VN in an efficient way has gained great attention. Existing algorithms generally make their decision according to the present available substrate network resource, especially bandwidth. This paper proposes a time-based VN embedding algorithm. A probability model is formulated to obtain the maximum probability that the available resources of substrate network can be used by succeeding VN requests. The probability is set as the weight of the node and the greedy algorithm is employed to embed the virtual node. The reciprocal of the probability is set as the weight of the link and the shortest path algorithm is employed to embed the virtual link. Simulation experiments show that the proposed algorithm increases the acceptance rate and the revenue compared to the existing algorithms. | JIANG Ming ZHAO Zhiyang ZHANG Min TANG Jingfan WU Chunming MIN Xiao | 2014 | Chinese Journal of Electronics2014，23，1： | 1 |
| 14 | Overview of Recombinant Skin Models and Progress in Their Application in Vitro Assessment of Toxicity and Efficacy显示文摘A recombinant skin model is a model in which skin cells are grown in vitro on a bioactive scaffold and provided with adequate nutrition to promote cell proliferation and differentiation to produce a mock skin structure and biological features. The development of recombinant skin models allows for effective and scientifically sound in vitro evaluation tests. This review briefly summarizes the overview of recombinant skin models and the progress of their application in in vitro evaluation which focuses on three aspects: skin irritation, skin corrosivity, and anti-skin aging. Moreover, an outlook on the future development of recombinant skin models is also provided in this review. | Zhang Bowen Xu Qiufeng GU Wu Zhang Zhichun Dai Yumeng Han Zhiyang Xu Mingkai Wang Yu | 2023 | China Detergent & Cosmetics2023，8，1： | 0 |
| 15 | Modeling and Analysis of the Impacts of Temporal-Spatial Variant Troposphere on Ground-Based SAR Imaging of Asteroids显示文摘The near-Earth asteroid collisions could cause catastrophic disasters to humanity and the Earth,so it is crucial to monitor asteroids.Ground-based synthetic aperture radar(SAR)is an observation technique for high resolution imaging of asteroids.The ground-based SAR requires a long integration time to achieve a large synthetic aperture,and the echo signal will be seriously affected by temporal-spatial variant troposphere.Traditional spatiotemporal freezing tropospheric models are ineffective.To cope with this,this paper models and analyses the impacts of temporal-spatial variant troposphere on ground-based SAR imaging of asteroids.For the background tropo-sphere,a temporal-spatial variant ray tracing method is proposed to trace the 4D(3D spatial+temporal)refractive index network provided by the numerical weather model,and calculate the error of the background troposphere.For the tropospheric turbulence,the Andrew power spectral model is used in conjunction with multiphase screen theory,and varying errors are obtained by tracking the changing position of the pierce point on the phase screen.Through simulation,the impact of temporal-spatial variant tropospheric errors on image quality is analyzed,and the simulation results show that the X-band echo signal is seriously affected by the troposphere and the echo signal must be compensated. | Tingting Fu Yuanhao Li Zhiyang Chen Zheng Wu Cheng Hu | 2023 | Journal of Beijing Institute of Technology2023，32，6： | 0 |
| 16 | Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients显示文摘Since the outbreak of coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),more than 6 million cases are confirmed and over 300,000 cases are dead after infection.Dysfunction of immunity in COVID-19 patients has been considered as one of the fatal factors for patients,especially cytokine release syndrome and lymphopenia.1,2,3 The reduced number and increased exhaustion level of lymphocyte are associated with elevated inflammatory cytokines in COVID-19 patients.4,5 However,the mechanism of cytokine-induced lymphopenia in COVID-19 is very unclear.IL-2 is critical for the proliferation,differentiation,and function of T cells,including Tregs,CD4+,and CD8+effector cells.6 Here,we reported the negative relationship between the concentration of soluble IL-2 receptor(sIL-2R)and T-cell number in blood from COVID-19 patients.In vitro addition of recombinant CD25 could inhibit the proliferation and function of T cells from PBMC after stimulated with TCR signaling,which could be rescued by strong IL-2 signaling.Our data suggested the importance of IL-2 signaling in lymphopenia of COVID-19 patients. | Yaguang Zhang Xiaojing Wang Xuezhen Li Dong Xi Ruizhi Mao Xiaohui Wu Shipeng Cheng Xiaoyu Sun Chunyan Yi Zhiyang Ling Liyan Ma Qin Ning Yiru Fang Bing Sun Di Wu | 2020 | Cellular & Molecular Immunology2020，17，8： | 0 |
| 17 | Construction of hierarchical FeNi_(3)@(Fe,Ni)S_(2) core-shell heterojunctions for advanced oxygen evolution显示文摘The investigation of earth-abundant electrocatalysts for efficient water electrolysis is of central importance in renewable energy system, which is currently impeded by the large overpotential of oxygen evolution reaction (OER). NiFe sulfides show promising OER activity but are troubled by their low intrinsic conductivities. Herein, we demonstrate the construction of the porous core-shell heterojunctions of FeNi3@(Fe,Ni)S_(2) with tunable shell thickness via the reduction of hierarchical NiFe(OH)x nanosheets followed by a partial sulfidization. The conductive FeNi3 core provides the highway for electron transport, and the (Fe,Ni)S_(2) shell offers the exposed surface for in situ generation of S-doped NiFe-oxyhydroxides with high intrinsic OER activity, which is supported by the combined experimental and theoretical studies. In addition, the porous hierarchical morphology favors the electrolyte access and O_(2) liberation. Consequently, the optimized catalyst achieves an excellent OER performance with a low overpotential of 288 mV at 100 mA·cm^(−2), a small Tafel slope of 48 mV·dec^(−1), and a high OER durability for at least 1,200 h at 200 mA·cm^(−2). This study provides an effective way to explore the advanced earth-abundant OER electrocatalysts by constructing the heterojunctions between metal and corresponding metal-compounds via the convenient post treatment, such as nitridation and sulfidization. | Minglei Yan Zhiyang Zhao Peixin Cui Kun Mao Chi Chen Xizhang Wang Qiang Wu Hui Yang Lijun Yang Zheng Hu | 2021 | Nano Research2021，14，11： | 0 |
| 18 | Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy显示文摘Purpose:We investigated the effects of retinal ischemia,neurodegeneration,and subclinical edema on best-corrected visual acuity(BCVA)in the early stages of diabetic retinopathy(DR).Methods:Ischemia was evaluated by the microvascular parameters measured by optical coherence tomography angiography.Neurodegeneration and subclinical edema were identified by the intraretinal layer thickness obtained by optical coherence tomography.Eyes with nonproliferative diabetic retinopathy(n=132)from 89 patients were analyzed.Eyes were classified as having normal BCVA(n=88[66.7%],Snellen equivalent≥20/20)or decreased BCVA(n=44[33.3%],Snellen equivalent<20/20).The prevalence of ischemia,neurodegeneration,and subclinical edema was explored in patients with and without decreased BCVA,and correlations between BCVA and these pathological pathways were determined.Results:Vessel density in the deep retinal capillary plexus(DRCP)and thickness of ganglion cell layer plus inner plexiform layer(GCL-IPL)were significantly lower in eyes with decreased BCVA compared with eyes with normal BCVA(both P<0.05).In the final multiple regression predictive model,age,DRCP vessel density,and GCL-IPL thickness(all P≤0.044)were predictors of BCVA.DRCP vessel density and GCL-IPL thickness have an interactive effect on visual acuity.The proportions of ischemia and neurodegeneration were significantly higher in eyes with decreased BCVA than in eyes with normal BCVA(P=0.001 and P=0.004,respectively).Conclusion:During the natural course of the early stages of DR,ischemia and neurodegeneration were the main disease pathways associated with visual acuity,and the mechanisms varied among patients. | Jin Li Yue Zhou Feng Chen Yingzi Li Rong Zhou Chaoming Wu Huankai Yu Zhiyang Lin Ce Shi Gu Zheng Yilei Shao Qi Chen Fan Lu Meixiao Shen | 2021 | Eye and Vision2021，8，1： | 0 |
| 19 | The Phytophthora effector Avh94 manipulates host jasmonic acid signaling to promote infection显示文摘The oomycete pathogen Phytophthora sojae is a causal agent of soybean root rot.Upon colonization of soybeans,P.sojae secretes various RXLR effectors to suppress host immune responses,supporting successful infection.Previous research has demonstrated that the RXLR effector Avh94 functions as a virulence effector,but the molecular mechanism underlying its role in virulence remains unknown.Here,we demonstrate that Avh94 overexpression in plants and pathogens promotes Phytophthora infection.Avh94 interacts with soybean JAZ1/2,which is a repressor of jasmonic acid(JA)signaling.Avh94 stabilizes JAZ1/2 to inhibit JA signaling and silencing of JAZ1/2 enhances soybean resistance against P.sojae.Moreover,P.sojae lines overexpressing Avh94 inhibit JA signaling.Furthermore,exogenous application of methyl jasmonate improves plant resistance to Phytophthora.Taken together,these findings suggest that P.sojae employs an RXLR effector to hijack JA signaling and thereby promote infection. | Yao Zhao Bo Yang Huawei Xu Jinbin Wu Zhiyang Xu Yuanchao Wang | 2022 | Journal of Integrative Plant Biology2022，64，11： | 0 |
| 20 | Indoor Positioning Using Public FM and DTMB Signals Based on Compressive Sensing显示文摘Location-Based Services have become an indispensable part of our daily life, the sparsity of location finding makes it possible to estimate specific position by Compressive Sensing(CS). Using public Frequency Modulation(FM) broadcasting and Digital Television Terrestrial Multimedia Broadcasting(DTMB) signals, this paper presents an indoor positioning scheme, which is consisted of an offline stage and an online stage. In the offline stage, the Received Signal Strength(RSS) at the Reference Points(RPs) is measured, including the average and variance of public FM broadcasting and DTMB signals. In the online stage, the K-Weighted Nearest Neighbor algorithm is used to fulfill coarse positioning, which is able to narrow the selection scope of locations and choose partial RPs for accurate positioning. Then, the accurate positioning is implemented through CS. Experiment shows that the average positioning error of the proposed scheme is 1.63 m. What’s more, a CS-based method has been proposed in this paper to reduce the labor cost when collecting data. Experiment shows the average positioning error is 2.04 m, with the advantage of a 34% labor cost reduction. Experiment results indicate that the proposed system is a practical indoor positioning scheme. | Menghuan Yang Hong Wu Zhiyang Liu Shuxue Ding Hongzhao Peng | 2019 | China Communications2019，16，5： | 0 |
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