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| 1 | HCloud:A Trusted JointCloud Serverless Platform for IoT Systems with Blockchain显示文摘Cloud computing has been exploited in managing large-scale IoT systems.IoT cloud servers usually handle a large number of requests from various IoT devices.Due to the fluctuant and heavy workload,the servers require the cloud to provide high scalability,stable performance,low price and necessary functionalities.However,traditional clouds usually offer computing service with the abstraction of virtual machine(VM),which can hardly meet these requirements.Meanwhile,different cloud vendors provide different performance stabilities and price models,which fluctuate according to the dynamic workload.A single cloud cannot satisfy all the requirements of the IoT scenario well.The JointCloud computing model empowers the cooperation among multiple public clouds.However,it is still difficult to dynamically schedule the workload on different clouds based on the VM abstraction.This paper introduces HCloud,a trusted JointCloud platform for IoT systems using serverless computing model.HCloud allows an IoT server to be implemented with multiple serverless functions and schedules these functions on different clouds based on a schedule policy.The policy is specified by the client and includes the required functionalities,execution resources,latency,price and so on.HCloud collects the status of each cloud and dispatches serverless functions to the most suitable cloud based on the schedule policy.By leveraging the blockchain technology,we further enforce that our system can neither fake the cloud status nor wrongly dispatch the target functions.We have implemented a prototype of HCloud and evaluated it by simulating multiple cloud providers.The evaluation results show that HCloud can greatly improve the performance of serverless workloads with negligible costs. | Zheng Huang Zeyu Mi Zhichao Hua | 2020 | China Communications2020,17,9: | 3 |
| 2 | Concurrent improvements of corrosion resistance and coercivity in Nd-Ce-Fe-B sintered magnets through engineering the intergranular phase显示文摘Usually the improved coercivity of rare earth(RE)based 2:14:1-type permanent magnets via RE-rich intergranular additives is achieved at the cost of more corrosion channels and deteriorated corrosion resistance,which remains a challenging hurdle in the RE-Fe-B community.Distinctly,here we report the concurrent improvements of corrosion resistance and coercivity in 40 wt.%Ce-substituted Nd-Ce-Fe-B sintered magnets through engineering the intergranular phase using simple(Nd,Pr)H_(x)additive.The dehydrogenated Nd/Pr changes the RE concentration gradients between 2:14:1 matrix and intergranular phases during sintering and enlarges the fraction of corrosion-resistant REFe_(2) phase,rather than the conventionally assumed Nd/Pr-rich intergranular phase with high chemical vulnerability.The spontaneous formation of REFe_(2) intergranular phase after(Nd,Pr)H_(x) addition generates the uniquely enhanced corrosion resistance against the hot/humid and acidic environments,and counts as one peculiar feature of Nd-Ce-Fe-B magnets at high Ce substitution level,being distinct from previously reported Ce-free/lean RE-Fe-B.Simultaneously,the formation of continuous grain boundaries enhances the coercivity from 8.7to 12.5 k Oe with trace addition of(Nd,Pr)H_(x).Above findings may spur progress towards developing a high-performance Nd-Ce-Fe-B permanent magnet. | Jiaying Jin Yongming Tao Xinhua Wang Zeyu Qian Wang Chen Chen Wu Mi Yan | 2022 | Journal of Materials Science & Technology2022,,15: | 1 |
| 3 | Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway显示文摘As a commonly used physical intervention,electrical stimulation(ES)has been demonstrated to be effective in the treatment of central nervous system disorders.Currently,researchers are studying the effects of electrical stimu-lation on individual neurons and neural networks,which are dependent on factors such as stimulation intensity,duration,location,and neuronal properties.However,the exact mechanism of action of electrical stimulation remains unclear.In some cases,repeated or prolonged electrical stimulation can lead to changes in the morphology or function of the neuron.In this study,immunofluorescence staining and Sholl analysis are used to assess changes in the neurite number and axon length to determine the optimal pattern and stimulation parameters of ES for neurons.Neuronal death and plasticity are detected by TUNEL staining and microelectrode array assays,respec-tively.mRNA sequencing and bioinformatics analysis are applied to predict the key targets of the action of ES on neurons,and the identified targets are validated by western blot analysis and qRT-PCR.The effects of alternating current stimulation(ACS)on neurons are more significant than those of direct current stimulation(DCS),and the optimal parameters are 3μA and 20 min.ACS stimulation significantly increases the number of neurites,the length of axons and the spontaneous electrical activity of neurons,significantly elevates the expression of growth-asso-ciated protein-43(GAP-43)without significant changes in the expression of neurotrophic factors.Furthermore,application of PI3K/AKT-specific inhibitors significantly abolishes the beneficial effects of ACS on neurons,con-firming that the PI3K/AKT pathway is an important potential signaling pathway in the action of ACS. | Hao Zhong Cong Xing Mi Zhou Zeyu Jia Song Liu Shibo Zhu Bo Li Hongjiang Yang Hongpeng Ma Liyue Wang Rusen Zhu Zhigang Qu Guangzhi Ning | 2023 | Acta Biochimica et Biophysica Sinica2023,55,11: | 0 |