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| 1 | Possible solutions for sludge dewatering in China显示文摘In China,over 1.43×10^(7)tons of dewatered sewage sludge,with 80%water content,were generated from wastewater treatment plants in 2007.About 60%of the COD removed during the wastewater treatment process becomes concentrated as sludge.Traditional disposal methods used by municipal solid waste treatment facilities,such as landfills,composting,or incineration,are unsuitable for sludge disposal because of its high water content.Disposal of sludge has therefore become a major focus of current environmental protection policies.The present status of sludge treatment and disposal methodology is introduced in this paper.Decreasing the energy consumption of sludge dewatering from 80%to 50%has been a key issue for safe and economic sludge disposal.In an analysis of sludge water distribution,thermal drying and hydrothermal conditioning processes are compared.Although thermal drying could result in an almost dry sludge,the energy consumption needed for this process is extremely high.In comparison,hydrothermal technology could achieve dewatered sewage sludge with a 50%–60%water content,which is suitable for composting,incineration,or landfill.The energy consumption of hydrothermal technology is lower than that required for thermal drying. | Wei WANG Yuxiang LUO Wei QIAO | 2010 | Frontiers of Environmental Science & Engineering2010，4，1： | 13 |
| 2 | Cationic content effects of biodegradable amphoteric chitosan-based flocculants on the flocculation properties显示文摘A series of biodegradable amphoteric chitosan-based flocculants(3-chloro-2-hydroxypropyl trimethyl ammonium chloride(CTA) modified carboxymethyl chitosan,denoted as CMC-CTA) with different substitution degrees of CTA were prepared successfully.The content of carboxymethyl groups in each CMC-CTA sample was kept almost constant.The solubility of the various flocculants showed that,higher cationic content of flocculants caused a better solubility.The flocculation experiments using kaolin suspension as synthetic water at the laboratory scale indicated that the substitution degree of CTA was one of the key factors for the flocculation properties.With the increase of cationic content,the flocculants were demonstrated better flocculation performance and lower dosage requirement.Flocculation kinetics model of particles collisions combining zeta potential and turbidity measurements was employed to investigate the effects of the cationic content of the flocculants on the flocculation properties from the viewpoint of flocculation mechanism in detail.Furthermore,flocculation performance using raw water from Zhenjiang part of Yangtze River at the pilot scale showed the similar effects to those at the laboratory scale. | Zhen Yang Yabo Shang Xin Huang Yichun Chen Yaobo Lu Aimin Chen Yuxiang Jiang Wei Gu Xiaozhi Qian Hu Yang Rongshi Cheng | 2012 | Journal of Environmental Sciences2012，24，8： | 8 |
| 3 | The Way to Apply Machine Learning to IoT Driven Wireless Network from Channel Perspective显示文摘Internet of Things(IoT) is one of the targeted application scenarios of fifth generation(5 G) wireless communication.IoT brings a large amount of data transported on the network.Considering those data,machine learning(ML) algorithms can be naturally utilized to make network efficiently and reliably.However,how to fully apply ML to IoT driven wireless network is still open.The fundamental reason is that wireless communication pursuits the high capacity and quality facing the challenges from the varying and fading wireless channel.So in this paper,we explore feasible combination for ML and IoT driven wireless network from wireless channel perspective.Firstly,a three-level structure of wireless channel fading features is defined in order to classify the versatile propagation environments.This three-layer structure includes scenario,meter and wavelength levels.Based on this structure,there are different tasks like service prediction and pushing,self-organization networking,self adapting largescale fading modeling and so on,which can be abstracted into problems like regression,classification,clustering,etc.Then,we introduce corresponding ML methods to different levelsfrom channel perspective,which makes their interdisciplinary research promisingly. | Wei Li Jianhua Zhang Xiaochuan Ma Yuxiang Zhang Hua Huang Yongmei Cheng | 2019 | China Communications2019，16，1： | 5 |
| 4 | Effect of sulfur source on photocatalytic degradation performance of CdS/MoS2 prepared with one-step hydrothermal synthesis显示文摘Cd S/Mo S_2,an extremely efficient photocatalyst,has been extensively used in hydrogen photoproduction and pollutant degradation.Cd S/Mo S_2can be synthesized by a facile one-step hydrothermal process.However,the effect of the sulfur source on the synthesis of Cd S/Mo S_2via one-step hydrothermal methods has seldom been investigated.We report herein a series of one-step hydrothermal preparations of Cd S/Mo S_2using three different sulfur sources:thioacetamide,L-cysteine,and thiourea.The results revealed that the sulfur source strongly affected the crystallization,morphology,elemental composition and ultraviolet(UV)–visible-light-absorption ability of the Cd S/Mo S_2.Among the investigated sulfur sources,thioacetamide provided the highest visible-light absorption ability for Cd S/Mo S_2,with the smallest average particle size and largest surface area,resulting in the highest efficiency in Methylene Blue(MB)degradation.The photocatalytic activity of Cd S/Mo S_2synthesized from the three sulfur sources can be arranged in the following order:thioacetamide>L-cysteine>thiourea.The reaction rate constants(k)for thioacetamide,L-cysteine,and thiourea were estimated to be 0.0197,0.0140,and 0.0084 min^(-1),respectively.However,thioacetamide may be limited in practical application in terms of its price and toxicity,while L-cysteine is relatively economical,less toxic and exhibited good photocatalytic degradation performance toward MB. | Yanfeng Wang Wei Chen Xiao Chen Huajun Feng Dongsheng Shen Bin Huang Yufeng Jia Yuyang Zhou Yuxiang Liang | 2018 | Journal of Environmental Sciences2018，30，3： | 3 |
| 5 | Changes in plant species composition and diversity of alpine Kobresia (Kobresia pygmaea) steppe meadow at different stages of desertification in the North Tibetan plateau显示文摘The impacts of desertification on the vegetation composition, structure, and species diversity of alpine Kobresia steppe meadow were evaluated in an area of severe desertification in Anduo County, Tibet Autonomous Region, northern China. We investigated and analyzed the floristic features of communities at four different stages of desertification (slight desertification [SLD], moderate desertification [MD], severe desertification [SD], and very severe desertification [VSD]). The composition and structure of the alpine Kobresia steppe meadow at the SLD site differed significantly from that at the MD, SD, and VSD sites. Species that were more drought resistant and inedible by livestock were the dominant species at the SD site. No plants were found in the shifting dunes of the VSD site. Species diversity also decreased with increasing desertification. The SLD site had the largest mean number of species and individuals and the largest richness index; the MD grassland had the largest Shannon-Wiener index and evenness index, but the smallest Simpson's index. The vegetation cover declined from 91.8% to 34.8% as desertification increased from SLD to SD, and reached 0% in VSD areas with shifting dunes. | XingHu Wei 1*, Ping Yang 2, Sen Li 1, YuXiang Dong 3, ChunLai Zhang 41. Department of Resources and Environmental of Foshan University, Foshan, Guangdong 528000, China.2. Resources and Environmental Bureau , Chinese Academy of Science, Lanzhou, Gansu 730000, China. 3. Department of Geography of Zhongshan University, Guangzhou, Guangdong 510275, China. 4. Beijing Normal University, Beijing 100875, China. | 2009 | Research in Cold and Arid Regions2009，1，1： | 3 |
| 6 | Genome-wide Investigation of micro RNAs and Their Targets in Brassica rapa ssp. pekinensis Root with Plasmodiophora brassicae Infection显示文摘Increasing evidence has revealed that micro RNAs play a pivotal role in the post transcriptional regulation of gene expression in response to pathogens in plants. However, there is little information available about the expression patterns of mi RNAs and their targets in Chinese cabbage(Brassica rapa ssp. pekinensis) under Plasmodiophora brassicae stress. In the present study, using deep sequencing and degradome analysis, a genome-wide identification of mi RNAs and their targets during P. brassicae stress was performed. A total of 221 known and 93 potentially novel mi RNAs were successfully identified from two root libraries of one control(635-10CK) and P. brassicae-treated Chinese cabbage samples(635-10T). Of these, 14 known and 10 potentially novel mi RNAs were found to be differentially expressed after P. brassicae treatment. Degradome analysis revealed that the 223 target genes of the 75 mi RNAs could be potentially cleaved. KEGG(Kyoto Encyclopedia of Genes and Genomes)pathway analysis suggested that the putative target genes of the mi RNAs were predominately involved in selenocompound metabolism and plant hormone signal transduction. Then the expression of 12 mi RNAs was validated by quantitative real-time PCR(q RT-PCR). These results provide insights into the mi RNA-mediated regulatory networks underlying the stress response to the plant pathogen P. brassicae. | WEI Xiaochun XU Wen YUAN Yuxiang YAO Qiuju ZHAO Yanyan WANG Zhiyong JIANG Wusheng ZHANG Xiaowei | 2016 | Horticultural Plant Journal2016，2，4： | 3 |
| 7 | Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial cancer显示文摘Objective:Lynch syndrome(LS)predisposes patients to early onset endometrioid endometrial cancer(EEC).However,little is known about LS-related EEC in the Chinese population.The aim of this study was to investigate the prevalence of LS and to identify the specific variants of LS in Chinese patients with EEC.Methods:We applied universal immunohistochemistry screening to detect the expression of mismatch repair(MMR)proteins,which was followed by MLH1 methylation analysis to identify suspected LS cases,next-generation sequencing(NGS)to confirm LS,and microsatellite instability(MSI)analysis to verify LS.Results:We collected 211 samples with EEC.Twenty-seven(27/211,12.8%)EEC cases had a loss of MMR protein expression.After MLH1 methylation analysis,16 EEC cases were suggested to be associated with LS.Finally,through NGS and MSI analysis,we determined that 10 EEC(10/209,4.78%)cases were associated with LS.Among those cases,3 unreported mutations(1 frameshift and 2 nonsense)were identified.M SH6 c.597_597delC,found in 4 patients,is likely to be a founder mutation in China.Conclusions:We demonstrated the feasibility of a process for LS screening in Chinese patients with EEC,by using universal immunohistochemistry screening followed by MLH1 methylation analysis and confirmation through NGS and MSI analysis.The novel mutations identified in this study expand knowledge of LS. | Caixia Ren Yan Liu Yuxiang Wang Yan Tang Yawei Wei Congrong Liu Hongquan Zhang | 2020 | Cancer Biology & Medicine2020，17，2： | 3 |
| 8 | The metabolic role of LncZBTB39-1:2 in the trophoblast mobility of preeclampsia显示文摘Preeclampsia is characterized by new onset of hypertension and proteinuria after 20 weeks’gestation and is a leading cause of maternal and neonatal morbidity and mortality.The pathogenesis of preeclampsia is often associated with aberrant trophoblast function that leads to shallow placental implantation.However,the exact underlying mechanisms remain unclear.Placental LncZBTB39-1:2 expression level was investigated in 20 healthy placentae and 20 placentae with preeclampsia using qRT-PCR,and the metabolic profile of trophoblasts overexpressing LncZBTB39-1:2 in vitro was analysed using gas chromatography-mass spectrometry(GCeMS).In this study,we found that the expression of LncZBTB39-1:2 was significantly higher in preeclamptic placentae than in healthy placentae.Our metabolomics results have shown that tricarboxylic acid cycle intermediates and metabolites related to carbohydrate metabolism were decreased with the overexpression of LncZBTB39-1:2 in HTR8/SVneo cells.These findings were validated by detecting a lower level of intracellular ATP in HTR8/Vneo cells.Furthermore,the migration of HTR8/SVneo cells was compromised when cells were transfected with a plasmid encompassing LncZBTB39-1:2 overexpression.From these results,we conclude that abnormal levels of LncZBTB39-1:2 expression might lead to aberrant conditions in HTR-8/SVneo trophoblast cells.Aberrant conditions might be associated with dysregulated trophoblast migration and subsequent failure of uterine spiral artery remodelling,a pathogenesis recognised as a contributing factor in the aetiology of preeclampsia. | Yamin Liu Ting-Li Han Xiaofang Luo Yuxiang Bai Xuehai Chen Wei Peng Xi Xiong Philip N.Baker Chao Tong Hongbo Qi | 2018 | Genes & Diseases2018，5，3： | 3 |
| 9 | Discrete element simulations and experiments of soil-winged subsoiler interaction显示文摘Understanding soil disturbance behaviors under the impact of the winged subsoiler is critical for designing or optimizing the winged subsoiler(a primary subsoiling tool).In this study,a soil-winged subsoiler interaction model was developed and the effects of winged subsoiler on soil disturbance behaviors were investigated using the discrete element method(DEM)simulations and lab soil-bin tests.The results showed that wings mainly affected the disturbance range and fragmentation degree of soil above them.The draught forces of share section(SS),arc section in the hardpan(ASHP),arc section in the top layer(ASTL)and line section(LS)were accounted for 69.53%,25.22%,4.73%and 0.52%of the total draught force of winged subsoiler;the lateral disturbance range from high to low of the soil at different depths followed the ranking:top layer(TL),hardpan disturbed by arc section(HDAS)and hardpan disturbed by share section(HDSS).Wings had the greatest influence on the draught force of ASHP.Adding wings to an arc-shaped subsoiler increased the disturbance areas of HDAS,TL and HDSS by 47.52%,7.74%and 4.59%,respectively,but meanwhile increased the total draught force by 36%.Compared with a non-winged subsoiler,winged subsoiler had higher soil looseness(15.83%),soil disturbance coefficient(58.59%),furrow width(448.65 mm)and soil disturbance area ratio(0.3835),but poorer soil surface flatness(19.79 mm)and lower soil loosening efficiency(39.35 mm²/N).This study provided critical information for optimizing winged subsoilers on aspects of improving soil loosening effectiveness and reducing draught force. | Xuezhen Wang Peng Li Jinpu He Wuquan Wei Yuxiang Huang | 2021 | International Journal of Agricultural and Biological Engineering2021，14，1： | 3 |
| 10 | ACBD3 is required for FAPP2 transferring glucosylceramide through maintaining the Golgi integrity显示文摘Glycosphingolipid (GSL) metabolism is involved in various physiological processes, including all major cell signaling pathways, and its dysregulation is linked to some diseases. The four-phosphate adaptor protein FAPP2-mediated glucosylceramide (GlcCer) transport for complex GSL synthesis has been studied extensively. However, the molecular machinery of FAPP2 as a GlcCer-transferring protein remains poorly defined. Here, we identify a Golgi-resident protein, acyl-coenzyme A binding domain containing 3 (ACBD3), as an interacting partner of FAPP2. We find that ACBD3 knockdown leads to dramatic Golgi fragmentation, which subsequently causes FAPP2 dispersal throughout the cytoplasm and a decreased localization at trans-Golgi network. The further quantitative Upidomic analysis indicates that ACBD3 knockdown triggers abnormal sphingolipid metabolism. Interestingly, the expression of siRNA-resistant full-length ACBD3 can rescue these defects caused by ACBD3 knockdown. These data reveal critical roles for ACBD3 in maintaining the integrity of Golgi morphology and cellular sphingolipid homeostasis and establish the importance of the integrated Golgi complex for the transfer of GlcCer and complex GSL synthesis. | Jing Liao Yuxiang Guan Wei Chen Can Shi Dongdong Yao Fengsong Wang Sin Man Lam Guanghou Shui Xinwang Cao | 2019 | Journal of Molecular Cell Biology2019，11，2： | 3 |
| 11 | Interacting plexcitons for designed ultrafast optical nonlinearity in a monolayer semiconductor显示文摘Searching for ideal materials with strong effective optical nonlinear responses is a long-term task enabling remarkable breakthroughs in contemporary quantum and nonlinear optics.Polaritons,hybridized light-matter quasiparticles,are an appealing candidate to realize such nonlinearities.Here,we explore a class of peculiar polaritons,named plasmon–exciton polaritons(plexcitons),in a hybrid system composed of silver nanodisk arrays and monolayer tungsten-disulfide(WS2),which shows giant room-temperature nonlinearity due to their deep-subwavelength localized nature.Specifically,comprehensive ultrafast pump–probe measurements reveal that plexciton nonlinearity is dominated by the saturation and higher-order excitation-induced dephasing interactions,rather than the well-known exchange interaction in traditional microcavity polaritons.Furthermore,we demonstrate this giant nonlinearity can be exploited to manipulate the ultrafast nonlinear absorption properties of the solid-state system.Our findings suggest that plexcitons are intrinsically strongly interacting,thereby pioneering new horizons for practical implementations such as energy-efficient ultrafast all-optical switching and information processing. | Yuxiang Tang Yanbin Zhang Qirui Liu Ke Wei Xiang’ai Cheng Lei Shi Tian Jiang | 2022 | Light(Science & Applications)2022，11，5： | 2 |
| 12 | CircuitNet:an open-source dataset for machine learning applications in electronic design automation(EDA)显示文摘The electronic design automation(EDA)community has been actively exploring machine learning(ML)for very large-scale integrated computer-aided design(VLSI CAD).Many studies explored learning-based techniques for cross-stage prediction tasks in the design flow to achieve faster design convergence.Although building ML models usually requires a large amount of data. | Zhuomin CHAI Yuxiang ZHAO Yibo LIN Wei LIU Runsheng WANG Ru HUANG | 2022 | Science China(Information Sciences)2022，65，12： | 2 |
| 13 | Bioenergy recovery from landfill gas:A case study in China显示文摘Landfill gas(LFG)utilization which means a synergy between environmental protection and bioenergy recovery was investigated in this study.Pressure swing adsorption technology was used in LFG purification,and laboratory experiment,pilot-scale test,and on-site demonstration were carried out in Shenzhen,China.In the laboratory experiment,A-type carbon molecular sieve was selected as the adsorbent by comparison of several other adsorbents.The optimal adsorption pressure and adsorption time were 0.25 MPa and 2 min,respectively,under which the product generation rate was 4.5 m^(3)/h and the methane concentration was above 90%.The process and optimization of the pilot-scale test were also reported in the paper.The product gas was of high quality compared with the National Standard of Compressed Natural Gas as Vehicle Fuel(GB18047-2000),when the air concentration in feed gas was under 10.96%.The demonstration project was composed of a collection system,production system,and utilization system.The drive performance,environmental protection performance,and economic feasibility of the product gas—as alternative fuel in passenger car,truck,and bulldozer—were tested,showing the feasibility technology for LFG utilization. | Wei WANG Yuxiang LUO Zhou DENG | 2009 | Frontiers of Environmental Science & Engineering2009，3，1： | 1 |
| 14 | Effects of Tert-Butylhydroquinone on Intestinal Inflammatory Response and Apoptosis following Traumatic Brain Injury in Mice显示文摘 | Wei Jin Hongbin Ni Yuxiang Dai Handong Wang Tianyu Lu Jun Wu Jian Jiang Weibang Liang Eric F. Morand | 2011 | Mediators of Inflammation2011，，： | 1 |
| 15 | MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B显示文摘 | Hongyan Guo Haiying Liu Keith Mitchelson Huiying Rao Mingyong Luo Lan Xie Yimin Sun Liang Zhang Ying Lu Ruyu Liu Aihui Ren Shuai Liu Shaozhen Zhou Jiye Zhu Yuxiang Zhou Ailong Huang Lai Wei Yong Guo Jing Cheng | 2011 | Hepatology2011，，3： | 1 |
| 16 | Green‑Solvent Processed Blade‑Coating Organic Solar Cells with an Efficiency Approaching 19%Enabled by Alkyl‑Tailored Acceptors显示文摘Power-conversion-efficiencies(PCEs)of organic solar cells(OSCs)in laboratory,normally processed by spin-coating technology with toxic halogenated solvents,have reached over 19%.However,there is usually a marked PCE drop when the bladecoating and/or green-solvents toward large-scale printing are used instead,which hampers the practical development of OSCs.Here,a new series of N-alkyl-tailored small molecule acceptors named YR-SeNF with a same molecular main backbone are developed by combining selenium-fused central-core and naphthalene-fused endgroup.Thanks to the N-alkyl engineering,NIR-absorbing YR-SeNF series show different crystallinity,packing patterns,and miscibility with polymeric donor.The studies exhibit that the molecular packing,crystallinity,and vertical distribution of active layer morphologies are well optimized by introducing newly designed guest acceptor associated with tailored N-alkyl chains,providing the improved charge transfer dynamics and stability for the PM6:L8-BO:YRSeNF-based OSCs.As a result,a record-high PCE approaching 19%is achieved in the blade-coating OSCs fabricated from a greensolvent o-xylene with high-boiling point.Notably,ternary OSCs offer robust operating stability under maximum-power-point tracking and well-keep>80%of the initial PCEs for even over 400 h.Our alkyl-tailored guest acceptor strategy provides a unique approach to develop green-solvent and blade-coating processed high-efficiency and operating stable OSCs,which paves a way for industrial development. | Hairui Bai Ruijie Ma Wenyan Su Top Archie Dela Pea Tengfei Li Lingxiao Tang Jie Yang Bin Hu Yilin Wang Zhaozhao Bi Yueling Su Qi Wei Qiang Wu Yuwei Duan Yuxiang Li Jiaying Wu Zicheng Ding Xunfan Liao Yinjuan Huang Chao Gao Guanghao Lu Mingjie Li Weiguo Zhu Gang Li Qunping Fan Wei Ma | 2023 | Nano-Micro Letters2023，15，12： | 1 |
| 17 | The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation显示文摘Acetaminophen(APAP)overdose is a major cause of liver injury.Neural precursor cell expressed developmentally downregulated 4—1(NEDD4-1)is an E3 ubiquitin ligase that has been implicated in the pathogenesis of numerous liver diseases;however,its role in APAP-induced liver injury(AILI)is unclear.Thus,this study aimed to investigate the role of NEDD4-1 in the pathogenesis of AILI.We found that NEDD4-1 was dramatically downregulated in response to APAP treatment in mouse livers and isolated mouse hepatocytes.Hepatocyte-specific NEDD4-1 knockout exacerbated APAP-induced mitochondrial damage and the resultant hepatocyte necrosis and liver injury,while hepatocyte-specific NEDD4-1 overexpression mitigated these pathological events both in vivo and in vitro.Additionally,hepatocyte NEDD4-1 deficiency led to marked accumulation of voltage-dependent anion channel 1(VDAC1)and increased VDAC1 oligomerization.Furthermore,VDAC1 knockdown alleviated AILI and weakened the exacerbation of AILI caused by hepatocyte NEDD4-1 deficiency.Mechanistically,NEDD4-1 was found to interact with the PPTY motif of VDAC1 through its WW domain and regulate K48-linked ubiquitination and degradation of VDAC1.Our present study indicates that NEDD4-1 is a suppressor of AILI and functions by regulating the degradation of VDAC1. | Yiwei Zhu Lin Lei Xinghui Wang Linfang Chen Wei Li Jinxia Li Chenchen Zhao Xiliang Du Yuxiang Song Wenwen Gao Guowen Liu Xinwei Li | 2023 | Acta Pharmaceutica Sinica B2023，13，4： | 1 |
| 18 | Heavy metal contamination in the sediment of the Second Songhua River显示文摘 | Chunye LIN Mengchang HE Baixing YAN Xiangchun QUAN Yuxiang ZHOU Wei GUO Zhifeng YANG | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 1 |
| 19 | Growth and properties of near-stoichiometric Fe:LiNbO3 crystals显示文摘 | ZHOU Yuxiang ZHENG Wei LIU Caixia | 2003 | J Chin Ceram Soc (in Chinese)2003，31，2： | 1 |
| 20 | Exome sequencing identifies rare mutations of LDLR and QTRT1 conferring risk for early-onset coronary artery disease in Chinese显示文摘Despite the advances made over the past decades,the known loci for coronary artery disease(CAD)still only explain<20%of the genetic variation in risk[1,2].The known loci with the strongest effects usually confer a 20%-37%increased CAD risk and the most loci modulate risk by≤10%[1].While most of the current data are from European populations,the use of trans-ethnic analyses could be helpful to identify additional loci.Genetic inheritance may impose a high burden on early-onset coronary artery disease(EOCAD). | Kang Yao Yuxiang Dai Juan Shen Yi Wang Huanjie Yang Runda Wu Qijun Liao Hongyi Wu Xiaodong Fang Shalaimaiti Shali Lili Xu Meng Hao Chenhao Lin Zhonghan Sun Yilian Liu Mengxin Li Zhen Wang Qiang Gao Shuning Zhang Chenguang Li Wei Gao Lei Ge Yunzeng Zou Aijun Sun Juying Qian Li Jin Shangyu Hong Yan Zheng Junbo Ge | 2022 | National Science Review2022，9，8： | 1 |
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