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| 1 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 2 | Development of machine learning models of :-cyclodextrin and sulfobutylether-β- cyclodextrin complication free energies 显示文摘 | Alexei M Yuriy A Abramov S | 2011 | Int J Pharm2011，418，2： | 1 |
| 3 | A thinning algorithm for GPS-based unbiased FIR estimation of a clock TIE model显示文摘 | Yuriy S S Oscar I M Luis A M | 2008 | Measurement2008，41，： | 1 |
| 4 | Acoustic analogue of electronic Bloch oscillations and resonant Zener tunne- ling in ultrasonic superlattices显示文摘 | Helios S A Yuriy A K Jose S D | 2007 | Physical Review Let- ters2007，98，13： | 1 |
| 5 | Active control of slow light on a chip with photonic crystal waveguides显示文摘 | Yurii A Vtasov Martin O'Boyle Hendrik F Hamann | 2005 | Nature2005，438，： | 1 |
| 6 | Polysulfide shuttle study in the LiS battery system显示文摘 | YURIY V MIKHAYLIK Z JAMES R A | 2004 | Journal of the Electrochemical Society2004，151，11： | 1 |
| 7 | Production of Dimethylfuran for Liquid Fuels from Biomass-derived Carbohydrates显示文摘 | Yuriy R Christopher J B James A D | 2007 | Nature2007，447，： | 1 |
| 8 | Phase modifiers promote efficient production of hydroxymethylfurfural from fructose显示文摘 | YURIY R L JUBEN N C JAMES A D | 2006 | Science2006，312，5782： | 1 |
| 9 | Laser diodes emitting up to 25 W at 808 nm显示文摘 | V V Bezotosnyi Vadim Yu Bondarev Oleg N Krokhin G T Mikaelyan V A Oleshchenko Valerii F Pevtsov Yurii M Popov E A Cheshev | 2009 | Quantum Electronics2009，，3： | 1 |
| 10 | McNab Active Control of Slow Light on a Chip with Photonic Crystal Waveguides 显示文摘 | YURII A VLASOV MARTIN O' BOYLE HENDRIK F HAMANN | 2005 | Nature2005，438，： | 1 |
| 11 | Losses in single-mode silicon-on-insulator strip waveguides and bends 显示文摘 | Yurii A Vlasov Sharee J McNab | 2004 | Op- tics Express2004，12，8： | 1 |
| 12 | Production of 5-hydroxymethylfurfural and furfural by dehydration of biomass-derived mono-and poly-saccharides 显示文摘 | Juben N Chheda Yuriy Roma'n Leshkov James A Dumesic | 2007 | Green Chemistry2007，，9： | 1 |
| 13 | Phase modifiers promote efficient production of hydroxymethylfurfural from fructose显示文摘 | Yuriy Román-Leshkov Juben N Chheda James A Dumesic | | 0，，5782： | 1 |
| 14 | New Approach for the Analysis of Damped Vibration of Fractionl Oscilhors 显示文摘 | Yuriy A R Marina V S | 2009 | Shock and Vibration2009，，16： | 1 |
| 15 | Multifunctioual magnetic-fluorescent nanocomposites for biomedical applications显示文摘 | Serena A C Yury P R Yurii K G | 2008 | Nanoscale Res Lett2008，3，： | 1 |
| 16 | Chemo-, Regio-, and Diastereoselective Hydrogenation of Oxopromegestone into Trimegestone over Supported Platinoids: Effects of the Transition Metal, Support Nature,Tin Additives, and Modifiers显示文摘 | Catherine C Santini Denis Prat | 2000 | J Catal2000，190，2： | 1 |
| 17 | Electrochemical activation of carbon nanowalls显示文摘 | VICTOR A YURII M BORIS I | 2011 | Mendeleev Communications2011，21，5： | 1 |
| 18 | Bubble interaction dynamics in Lagrangian and Hamiltonian mechanics显示文摘 | Yurii A Ilinskii Mark F | 2007 | Acoustical Society of America2007，121，2： | 1 |
| 19 | Cooperative radiation and scattering if acoustic waves by gas bubbles in liquids显示文摘 | Yurii A Ilinskii E A Zabolotskaya | 1992 | Acoustical Society of America1992，92，5： | 1 |
| 20 | On-chip natural assembly of silicon photonic bandgap crystals显示文摘 | Yurii A Vlasov Xiang-zheng Bo James C Sturm | 2001 | Nature2001，414，15： | 1 |
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