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| 1 | Structural insights of phosphorylated into the recognition FUNDC1 by LC3B in mitophagy显示文摘 | Mengqi Lv Chongyuan Wang Fudong Li Junhui Peng Bin Wen Qingguo Gong Yunyu Shi Yajun-Tang | 2017 | Protein & Cell2017，8，1： | 21 |
| 2 | Structure of the YTH domain of human YTHDF2 in complex with an m6A mononucleotide reveals an aromatic cage for m6A recognition显示文摘 | Fudong Li Debiao Zhao Jihui Wu Yunyu Shi | 2014 | Cell Research2014，24，12： | 16 |
| 3 | Characterization and evaluation of rice blast resistance of Chinese indica hybrid rice parental lines显示文摘The development of resistant varieties and hybrid combinations has been the most effective and economical strategy to control blast disease caused by Magnaporthe oryzae.However, the distribution of major R genes and blast resistance characterization in hybrid rice parents has not been well investigated, resulting in their limited use in hybrid rice blast-resistance breeding. In the present study, 88 elite indica hybrid rice parental lines were evaluated with 30 isolates of M. oryzae collected from the main planting area of indica hybrid rice in China and were characterized for the presence of 11 major resistance genes using molecular markers. The pathogenicity assays showed that four types of hybrid rice parent line showed some resistance to M. oryzae. However, the proportions of highly resistant lines and the mean resistance frequency(RF) varied among the four types, with resistance in decreasing order shown by three-line restorer lines, three-line maintainer lines, two-line sterile lines, and two-line restorer lines. All 88 hybrid rice parental lines carried more than one R gene, but none carried the R genes Pi1 and Pi2. Although Pid3 and Pi9 were present only in three-line restorer lines and Pigm only in three-line maintainer lines, the remaining six R genes(Pib, Pid2, Pi5, Pia, Pi54, and Pita) were present in the four types of hybrid rice parent with significantly different distribution frequencies. The correlation between R genes and resistance reactions was investigated. The results are expected to provide useful information for rational utilization of major R genes in hybrid rice breeding programs. | Yunyu Wu Ling Yu Ning Xiao Zhengyuan Dai Yuhong Li Cunhong Pan Xiaoxiang Zhang Guangqing Liu Aihong Li | 2017 | The Crop Journal2017，5，6： | 10 |
| 4 | Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions显示文摘Genotyping and phenotyping large natural populations provide opportunities for population genomic analysis and genome-wide association studies(GWAS). Several rice populations have been re-sequenced in the past decade;however, many major Chinese rice cultivars were not included in these studies. Here, we report large-scale genomic and phenotypic datasets for a collection mainly comprised of 1,275 rice accessions of widely planted cultivars and parental hybrid rice lines from China. The population was divided into three indica/Xian and three japonica/Geng phylogenetic subgroups that correlate strongly with their geographic or breeding origins. We acquired a total of 146 phenotypic datasets for 29 agronomic traits under multi-environments for different subpopulations. With GWAS, we identified a total of 143 significant association loci, including three newly identified candidate genes or alleles that control heading date or amylose content. Our genotypic analysis of agronomically important genes in the population revealed that many favorable alleles are underused in elite accessions, suggesting they may be used to provide improvements in future breeding efforts. Our study provides useful resources for rice genetics research and breeding. | Xiuxiu Li Zhuo Chen Guomin Zhang Hongwei Lu Peng Qin Ming Qi Ying Yu Bingke Jiao Xianfeng Zhao Qiang Gao Hao Wang Yunyu Wu Juntao Ma Liyan Zhang Yongli Wang Lingwei Deng Shanguo Yao Zhukuang Cheng Diqiu Yu Lihuang Zhu Yongbiao Xue Chengcai Chu Aihong Li Shigui Li Chengzhi Liang | 2020 | Science China(Life Sciences)2020，63，11： | 8 |
| 5 | A Novel Multiscale Reinforcement by In-Situ Growing Carbon Nanotubes on Graphene Oxide Grafted Carbon Fibers and Its Reinforced Carbon/Carbon Composites with Improved Tensile Properties显示文摘In-situ growing carbon nanotubes(CNTs)directly on carbon?bers(CFs)always lead to a degraded tensile strength of CFs and then a poor?ber-dominated mechanical property of carbon/carbon composites(C/Cs).To solve this issue,here,a novel carbon?ber-based multiscale reinforcement is reported.To synthesize it,carbon?bers(CFs)have been?rst grafted by graphene oxide(GO),and then carbon nanotubes(CNTs)have been in-situ grown on GO-grafted CFs by catalytic chemical vapor deposition.Characterizations on this novel reinforcement show that GO grafting cannot only nondestructively improve the surface chemical activity of CFs but also protect CFs against the high-temperature corrosion of metal catalyst during CNT growth,which maintains their tensile properties.Tensile property tests for unidirectional C/Cs with different preforms show that this novel reinforcement can endow C/C with improved tensile properties,32% and 87%higher than that of pure C/C and C/C only doped with in-situ grown CNTs.This work would open up a possibility to fabricate multiscale C/Cs with excellent global performance. | Yunyu Li Ling-jun Guo Ya-wen Wang He-jun Li Qiang Song | 2016 | Journal of Materials Science & Technology2016，32，5： | 8 |
| 6 | Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation显示文摘在房间期间,分割要求忠诚有丝分裂的锭子汇编和染色体分离的基因信息的稳定的传播。运用了 GTPase 戏在有丝分裂的锭子汇编的一个关键角色。然而,在锭子的 Ran-GTP 的一个化学坡度的产生怎么被联合到有丝分裂的 translational 以后修正,从来没被描绘过。这里,我们解决了复杂结构与核苷酸版本因素 Mog1 跑了并且描出一个新奇有丝分裂特定的调整 acetylation 的 Ran-Mog1 相互作用在染色体分离期间。我们的指导结构的功能的分析表明那 Mog1 与 RCC1 竞争为以一种 GTP/GDP-dependent 方式变有约束力。生物化学的描述表明了那 Mog1 固定跑阻止 RCC1 有约束力、随后的 GTP 装载。令人惊讶地,跑了是 TIP60 的真正的底层,并且由 TIP60 的 Lys134 的 acetylation 解放 Mog1 从在有丝分裂期间变有约束力。重要地,这个得到 acetylation 的开关对 RCC1 变有约束力支持 Ran-GTP 的高水平,它为染色体排列是必要的。这些结果建立一以前 TIP60 由调节在提供 Ran-GTP 水平的 homeostatic 控制的规章的机制运用了的 uncharacterized 为在有丝分裂的染色体分离的受动器绑定。 | Xiaoling Bao Heng Liu Xing Liu Ke Ruan Yonshui Zhang Zhiyong Zhang Qi Hu Ying Liu Saima Akram Jiahai Zhang Qingguo Gong Wenwen wang Xiao Yuan Jian-Li Lingli Zhao Zhen Dou Ruijun Tian Xuebiao Yao Jihui Wu Yunyu Shi | 2018 | Journal of Molecular Cell Biology2018，10，1： | 8 |
| 7 | 针对Terra/MODIS数据的改进分裂窗地表温度反演算法(英文)显示文摘针对Terra/MODIS数据提出改进的分裂窗地表温度反演算法。充分考虑了传感器观测角度(VZA)的影响,并对地表和有效大气辐射按照不同的亮度温度区间分别进行Planck函数简化。利用TIGR3大气廓线库中的875条晴空大气廓线,ASTER波谱库中的106条地物发射率波谱,结合MODTRAN4大气辐射传输模型模拟得到分裂窗算法系数。利用MODTRAN4模拟数据对算法精度进行验证,结果表明本文的改进算法和原算法的均方根误差RMSE分别为0.34K和0.65K。敏感性分析表明,在中等湿润的大气条件下,算法对大气水汽含量并不敏感。该算法降低了传感器观测角度带来的地表温度反演误差。利用2009年6月美国SURFRAD辐射观测网6个站点的实测数据对改进算法、原算法以及MOD11_L2地表温度产品进行了对比验证,RMSE分别是0.93K、1.49K和1.0K,表明本文算法可以提高反演精度。 | Ri Changin 柳钦火 历华 方莉 YU Yunyue SUN Donglian | 2013 | 遥感学报2013，17，4： | 8 |
| 8 | Gene diagnosis and targeted breeding for blast-resistant Kongyu 131without changing regional adaptability显示文摘The fungus Magnaporthe oryzae threatens the rice production of Kongyu 131 (KY131),a leading japonica variety in Northeast China.In this study,two rice lines,KP1 and KP2-Hd1,were obtained by introgressing the blast resistance genes Pi1 and Pi2 into KY131,respectively.However,both lines headed later than KY131.RICE60K SNP array analysis showed that Hd1 closely linked to Pi2 was introgressed into KP2-Hd1,and the linkage drag of Hd1 was broken by recombination.On the other hand,no known flowering genes were introgressed into KP1.Gene diagnosis by resequencing six flowering genes showed that KP1 carried functional Hd16 and Ghd8 alleles.Due to its suppression role in heading under long-day conditions,Ghd8 was chosen as the target for gene editing to disrupt its function.Four sgRNAs targeting different sites within Ghd8 were utilized to induce large-deletion mutations,which were easy to detect via agarose gel electrophoresis.All the ghd8-mutated KP1 lines were resistant to rice blast disease and headed earlier than the control KP1,even than KY131,under natural long-day conditions,which ensures its growth in Northeast China.This study confirmed that a combination of gene diagnosis and targeted gene editing is a highly efficient way to quickly eliminate undesired traits in a breeding line. | Xiangchun Zhou Gonghao Jiang Longwei Yang Lei Qiu Ping He Chunxiao Nong Yunyue Wang Yuqing He Yongzhong Xing | 2018 | Journal of Genetics and Genomics2018，45，10： | 7 |
| 9 | Strategy for Use of Rice Blast Resistance Genes in Rice Molecular Breeding显示文摘Rice blast is one of the most destructive diseases affecting rice production worldwide.The development and rational use of resistant varieties has been the most effective and economical measure to control blast.In this review,we summarized the cloning and utilization of rice blast resistance genes,such as Pi1,Pi2,Pi9,Pi54,Pigm and Piz-t.We concluded that three main problems in the current breeding of rice blast resistance are:availability of few R(resistance)genes that confer resistance to both seedling and panicle blast,the resistance effect of pyramided lines is not the result of a simple accumulation of resistance spectrum,and only a few R genes have been successfully used for molecular breeding.Therefore,novel utilization strategies for rice blast R genes in molecular breeding were proposed,such as accurately understanding the utilization of R genes in main modern rice varieties,creating a core resistant germplasm with excellent comprehensive traits,screening and utilizing broadspectrum and durable resistance gene combinations.Lastly,the trends and possible development direction of blast resistance improvement were also discussed,including new genes regulating resistance identified via GWAS(genome-wide association study)and improving rice blast resistance using genetic editing. | XIAO Ning WU Yunyu LI Aihong | 2020 | Rice science2020，27，4： | 7 |
| 10 | The Effect of Repetitive Transcranial Magnetic Stimulation on the Reinstatement of Methamphetamine-lnduced Conditioned Place Preference in Rats显示文摘 | Xueqing WU Yunyue JU Dongliang JIAO Min ZHAO | 2018 | 上海精神医学2018，30，3： | 6 |
| 11 | Remote sensing of earth’s energy budget:synthesis and review显示文摘The Earth’s climate is largely determined by its energy budget.Since the 1960s,satellite remote sensing has been used in estimating these energy budget components at both the top of the atmosphere(TOA)and the surface.Besides the broadband sensors that have been traditionally used for monitoring Earth’s Energy Budget(EEB),data from a variety of narrowband sensors aboard both polar-orbiting and geostationary satellites have also been extensively employed to estimate the EEB components.This paper provides a comprehensive review of the satellite missions,state-of-the art estimation algorithms and the satellite products,and also synthesizes current understanding of the EEB and spatiotemporal variations.The TOA components include total solar irradiance,reflected shortwave radiation/planetary albedo,outgoing longwave radiation,and energy imbalance.The surface components include incident solar radiation,shortwave albedo,shortwave net radiation,longwave downward and upwelling radiation,land and sea surface temperature,surface emissivity,all-wave net radiation,and sensible and latent heat fluxes.Some challenges,and outlook such as virtual constellation of different satellite sensors,temporal homogeneity tests of long time-series products,algorithms ensemble,and products intercomparison are also discussed. | Shunlin Liang Dongdong Wang Tao He Yunyue Yu | 2019 | International Journal of Digital Earth2019，12，7： | 5 |
| 12 | Motion-based pH sensing using spindle-like micromotors显示文摘在这研究,我们报导一台像锭子的微电机。这台设备,用一个一步舞 electrospinning 方法被制作,由可被细菌破坏的 polycaprolactone 和 anionic 表面活化剂组成。有趣地,不是仅仅,产生微电机能为时间的一个长时期在水的表面上独立地移动(~ 40 min )由于 Marangoni 效果,但是在表面活化剂的版本在不同 pH 条件下面引起的表面紧张由于变化察觉到行为也展出 pH 。更有趣地,我们表明察觉到性质的基于运动的 pH 是尺寸依赖者,与展出更高的敏感的更小的结构。另外,自从 polycaprolactone 是可被细菌破坏的材料,微电机在这描述了学习能容易在答案被降级。因此,象一步舞制造,运动读出,和 biodegradability 那样的特征显示这台微电机察觉到应用的一个吸引人的候选人。 | Limei Liu Yonggang Dong Yunyu Sun Mei Liu Yajun Su Hui Zhang Bin Dong | 2016 | Nano Research2016，9，5： | 4 |
| 13 | Dual-Fuel-Driven Bactericidal Micromotor显示文摘In this paper, we report fabrication of the bimetallic Janus microsphere, a magnesium microsphere with a silver surface coating, through thermal evaporation technique. Because of the Janus structure, this micromotor can be propelled in two different directions by the surface silver or magnesium ‘engine' and hydrogen peroxide or water fuel. In addition, due to the bactericidal property of silver, this autonomous micromotor is capable of killing bacteria in solution. As compared to the static one, the micromotor is able to kill the bacteria at a much faster rate(about nine times of that of the static one),demonstrating the superiority of the motion one. We thus believe that the micromotor shown in the current study is potentially attractive for the environmental hygiene applications. | Ya Ge Mei Liu Limei Liu Yunyu Sun Hui Zhang Bin Dong | 2016 | Nano-Micro Letters2016，8，2： | 3 |
| 14 | Application of Traditional Chinese Medicine in medical practice:a survey of community residents in Beijing,China显示文摘OBJECTIVE:To investigate how community residents in Beijing understood and used Traditional Chinese Medicine(TCM) in their medical practice.METHODS:This was a cross-sectional study conducted on 3410 community residents from four large communities of Tongzhou district in Beijng,China.A validated, self-administered questionnaire comprised of three sections was used to gather the data.A systematic sampling procedure was applied to recruit the community residents.RESULTS:A total of 3410 participants completed the questionnaire survey.It showed that in highly educated residents, 33.4%(170) knew of the names of 3-10 Chinese herbals, 35.8%(182) knew of names of 3-10 traditional Chinese patent drug.Among all the respondent residents, 80.7%(2753)believed that TCM herbal therapy and TCM non-drug treatments were effective in disease treatment, health enhancement, 85.7%(2923) had taken traditional Chinese patent drug in their life,56.8%(1937) of residents had used herbal decoction, 40.0%(1365) had received non-drug treatment of TCM, such as acupuncture, massage, cupping, auricular acupuncture.Among the elderly residents, 11.4%(98) often used Chinese patent drug and 9.8%(85) often used herbal decoction.In addition, 70.8%(2415) of residents were willing to accept knowledge and information on TCM for health enhancement and disease prevention, such as medicated diet, medicinal tea, Tai Chi and Qi Gong, although 82.8%(2825) of residents had never used them.CONCLUSION:Chinese patent drug and herbal decoction are widely used in the communities in Beijing, and there existed a possible close correlation between high educational level and better understanding of TCM.Age and occupation also correlated with the attitude to TCM therapies.The characteristics of the residents should be considered seriously in the course of promoting the understanding and application of TCM. | Liu Zhongdi Huang Yunyu Cui Zhaoli Tan Yong Yang Jing Lü Aiping Wang Yaoxian Jiang Miao | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 3 |
| 15 | NOx Emission Reduction Technology for Marine Engine Based on Tier-Ⅲ:A Review显示文摘The development of maritime trade has greatly promoted the development of diesel engines.However,with the increasingly serious environmental problems,more and more attention has been paid to the exhaust emissions of high-power marine diesel engines.The restrictions on SOx have been implemented globally,and the limitation of the NO,will be the next priority.This paper illustrates(a)Principle and research progress of NOx emissions-reduction technology of marine diesel engine;(b)Summary of advantages and disadvantages among various reduction technologies and their reduction effects;(c)The application effect of mainstream technology on board.Firstly,since exhaust gas recirculation(EGR)can achieve Tier-Ⅲ directly from Tier-Ⅰ without considering the increased fuel consumption.It is deemed as the most promising technology to reduce emissions by controlling combustion condition.However,EGR has shortcomings of excessive increase in ftiel consumption and generation of waste water,which need to be solved immediately.Secondly,selective catalytic reduction(SCR)is the most effective and straightforward means to achieve Tier-Ⅲ.Despite of the continuous optimization of SCR unit volume,the problem of scrap catalyst seriously limits its wide application.How to match the supercharger more efficiently is a key factor in choosing between high and low pressure SCR.Thirdly,nature gas(NG)engines are capable of achieving a reduction in NOx,but in order to meet the requirements of Tier-Ⅲ,it still needs to be assisted by other technologies.The emissions of hydrocarbon(HC)and CO in NG engines are huge defects that must be solved.Lastly,technologies such as the Miller cycle,Two-stage supercharging and mixed-water combustion can also reduce emissions but were rarely used alone.These technologies can be combined with EGR,SCR and NG engines to optimize the enginesJ economy and emission characteristics. | LU Xiuwei GENG Peng CHEN Yunyue | 2020 | Journal of Thermal Science2020，29，5： | 2 |
| 16 | Fairness-improved and QoS-guaranteed resource allocation for NOMA-based S-IoT network显示文摘Dear editor,Recently, the satellite-integrated Internet of Things(S-IoT)has supported many emergent IoT applications [1], such as smart agriculture, remote healthcare, and environmental monitoring [2]. To make full use of the broadband access ability of S-IoT, nonorthogonal multiple access(NOMA)techniques are used to simultaneously support multiple terrestrial user terminals(UTs). | Jian JIAO Shiyi LIAO Yunyu SUN Shaohua WU Qinyu ZHANG | 2021 | Science China(Information Sciences)2021，64，6： | 2 |
| 17 | A new approach to the bicyclo[3.3.1]nonane framework of huperzine A-like molecules via palladium-catalyzed intramolecular γ-arylation显示文摘In our synthetic studies toward huperzine A, a diastereoselective α′-alkylation of the α-amido-γ-methyl hexenone 4 was realized through a dianion intermediate which significantly enhanced the reactivity. Under the attempted Heck reaction conditions, an unexpected and unprecedented palladium-catalyzed intramolecular γ-arylation of 3 was observed, which generated 18 with bicyclo[3.3.1]nonane framework in satisfactory yield. | DING Rui LU YunYu YAO HeQuan SUN BingFeng LIN GuoQiang | 2012 | Science China Chemistry2012，55，6： | 2 |
| 18 | Expression Profile and Function Analysis of Long Non-coding RNAs in the Infection of Coxsackievirus B3显示文摘The roles of IncRNAs in the infection of enteroviruses have been barely demonstrated.In this study,we used coxsackievirus B3(CVB3),a typical enterovirus,as a model to investigate the expression profiles and functional roles of IncRNAs in enterovirus infection.We profiled IncRNAs and mRNA expression in CVB3-infected HeLa cells by IncRNA-mRNA integrated microarrays.As a result,700 differentially expressed IncRNAs(431 up-regulated and 269 down-regulated)and 665 differentially expressed mRNAs(299 up-regulated and 366 down-regulated)were identified in CVB3 infection.Then we performed IncRNA-mRNA integrated pathway analysis to identify potential functional impacts of the differentially expressed mRNAs,in which IncRNA-mRNA correlation network was built.According to IncRNA-mRNA correlation,we found that XLOC-001188,an IncRNA down-regulated in CVB3 infection,was negatively correlated with NFAT5 mRNA,an anti-CVB3 gene reported previously.This interaction was supported by qPCR detection following siRNA-mediated knockdown of XLOC-001188,which showed an increase of NFAT5 mRNA and a reduction of CVB3 genomic RNA.In addition,we observed that four most significantly altered IncRNAs,SNHG11,RP11-145F16.2,RP11-1023L17.1 and RP11-1021N1.2 share several common correlated genes critical for CVB3 infection,such as BRE and IRF2BP1.In all,our studies reveal the alteration of IncRNA expression in CVB3 infection and its potential influence on CVB3 replication,providing useful information for future studies of enterovirus infection. | Lei Tong Ye Qiu Hui Wang Yunyue Qu Yuanbo Zhao Lexun Lin Yan Wang Weizhen Xu Wenran Zhao Hongyan He Guangze Zhao Mary HZhang Decheng Yang Xingyi Ge Zhaohua Zhong | 2019 | Virologica Sinica2019，34，6： | 2 |
| 19 | Starch supplementation improves the reproductive performance of sows in different glucose tolerance status显示文摘This study was to evaluate the effects of glucose tolerance status,maternal starch supplementation and soybean substitution in diets on the performance of dams and their offspring.Eighty-eight pregnant sows(Landrace x Large White)were selected from an initial total of 120 sows,based on blood glucose test values,and assigned to 4 experimental treatments in a 2×2 factorial design.The factors were glucose tolerance status(glucose intolerant[GIT]vs.normal glucose tolerant[NGT])or dietary treatments(corn starch diet[CS]vs.soybean substitution diet[SSI]).A higher area under the curve(AUC)for post-meal glucose was observed(P<0.05)in the GIT group than in the NGT group on d 109 of gestation.The CS group had a lower value of homeostasis model assessment-insulin resistance than the SS group(P<0.05)on d 109 of gestation.Corn starch supplementation for sows decreased the stillbirth rate(P<0.05),regardless of the sows’glucose tolerance status.The villus height of the jejunum and the villus height to crypt depth ratio of the ileum were greater in normal birth weight piglets from the CS group than from the SS group(P<0.01),and so was the activity of sucrase in the jejunum and ileum(P<0.01).Compared with the SS group,the CS group showed a reduction in pre-weaning mortality rate,an increase in the number of high-birth-weight piglets,and a decrease in the number of low-birth-weight piglets(P<0.05)under GIT status.In conclusion,sows fed CS decreased stillbirth rate and improved insulin resistance,as well as improving the intestinal morphology and digestive enzyme activities of their progeny,regardless of glucose tolerance status.Additionally,the CS group improved birth weight distribution and decreased pre-weaning mortality rate of piglets under GIT status. | Yunyu Yang Ming Deng Jianzhao Chen Xichen Zhao Kaili Xiao Wenliang He Xinggang Qiu Yanzhen Xu Yulong Yin Chengquan Tan | 2021 | Animal Nutrition2021，，4： | 2 |
| 20 | Identification of Damage on Different Plants Caused by Botrytis cinerea and its Extracellular Macromolecular Toxin显示文摘With Botrytis cinerea and its extracellular macromolecular toxins as the test materials,30 speices of plants belonging to 29 genera and 21 families were selected as the test plants to observe the infectivity of B. cinerea and damage status of macromolecular toxins secreted by B. cinerea on plants. The resulsts showed that 17 species of plants were both infected by B. cinerea and damaged by toxins,accounting for 56.7% of the total plants. Two species of plants could be neither infected by B. cinerea nor damaged by toxins. The study provided the reference for further understanding of pathogenic mechanism of plant pathogenic fungi toxins. | Hu Hailin Dong Qionge Wu Jia Huo Da Wang Yunyue Yang Hongyu | 2013 | Plant Diseases and Pests2013，4，3： | 2 |
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