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| 1 | DBPM signal processing with field programmable gate arrays显示文摘DBPM system performance is determined by the design and implementation of beam position signal processing algorithm.In order to develop the system,a beam position signal processing algorithm is implemented on FPGA.The hardware is a PMC board ICS-1554A-002(GE Corp.)with FPGA chip XC5VSX95T.This paper adopts quadrature frequency mixing to down convert high frequency signal to base.Different from conventional method,the mixing is implemented by CORDIC algorithm.The algorithm theory and implementation details are discussed in this paper.As the board contains no front end gain controller,this paper introduces a published patent-pending technique that has been adopted to realize the function in digital logic.The whole design is implemented with VHDL language. An on-line evaluation has been carried on SSRF(Shanghai Synchrotron Radiation Facility)storage ring.Results indicate that the system turn-by-turn data can measure the real beam movement accurately,and system resolution is 1.1μm. | LAI Longwei LENG Yongbin YI Xing YAN Yingbing ZHANG Ning YANG Guisen WANG Baopeng XIONG Yun | 2011 | Nuclear Science and Techniques2011，22，3： | 10 |
| 2 | Gene diagnosis and targeted breeding for blast-resistant Kongyu 131without changing regional adaptability显示文摘The fungus Magnaporthe oryzae threatens the rice production of Kongyu 131 (KY131),a leading japonica variety in Northeast China.In this study,two rice lines,KP1 and KP2-Hd1,were obtained by introgressing the blast resistance genes Pi1 and Pi2 into KY131,respectively.However,both lines headed later than KY131.RICE60K SNP array analysis showed that Hd1 closely linked to Pi2 was introgressed into KP2-Hd1,and the linkage drag of Hd1 was broken by recombination.On the other hand,no known flowering genes were introgressed into KP1.Gene diagnosis by resequencing six flowering genes showed that KP1 carried functional Hd16 and Ghd8 alleles.Due to its suppression role in heading under long-day conditions,Ghd8 was chosen as the target for gene editing to disrupt its function.Four sgRNAs targeting different sites within Ghd8 were utilized to induce large-deletion mutations,which were easy to detect via agarose gel electrophoresis.All the ghd8-mutated KP1 lines were resistant to rice blast disease and headed earlier than the control KP1,even than KY131,under natural long-day conditions,which ensures its growth in Northeast China.This study confirmed that a combination of gene diagnosis and targeted gene editing is a highly efficient way to quickly eliminate undesired traits in a breeding line. | Xiangchun Zhou Gonghao Jiang Longwei Yang Lei Qiu Ping He Chunxiao Nong Yunyue Wang Yuqing He Yongzhong Xing | 2018 | Journal of Genetics and Genomics2018，45，10： | 7 |
| 3 | Abiogenic hydrocarbons in commercial gases from the Songliao Basin,China显示文摘This paper discusses the kinetic fractionation, composition and distribution characteristics of carbon and hydrogen isotopes for various alkane gases formed in different environments, by different mecha- nisms and from different sources in nature. It is demonstrated that the biodegradation or thermode- gradation of complex high-molecule sedimentary organic material can form microbial gas or thermogenic gas. The δ 13C1 value ranges from -110‰ to -50‰ for microbial gases but from -50‰ to -35‰ (even heavier) for thermogenic gases. Controlled by the kinetic isotope fractionation, both microbial and thermogenic gases have δ 13C and δ D values characterized by normal distribution, i.e. δ 13C1< δ 13C2< δ 13C3< δ 13C4 and δ DCH4< δ DC2H6< δ DC3H8<δ DC4H10, and by a positive correlation between the δ 13C and δ D values. Simple carbonbearing molecules (CH4, CO and CO2) can form abiogenic alkane gases via polymerization in the abiological chemical process in nature, with δ 13C1 heavier than -30‰. Moreover, controlled by the kinetic isotope fractionation, abiogenic alkane gases are characterized by a reverse distribution of δ 13C values and a normal trend of δ D values, namely δ 13C1> δ 13C2> δ 13C3> δ 13C4 and δ DCH4<δ DC2H6< δ DC3H8< δ DC4H10. The δ 13C values and δ D values are negatively correlated. Natural gases from 26 commercial gas wells distributed in the Xujiaweizi and Yingshan-Miaotaizi faulted depressions in the Songliao Basin, China, show δ13C1 values ranging from -30.5‰ to -16.7‰ with a very narrow δ D range between -203‰―-196‰. These gases are characterized by a reverse distribution of δ 13C values but a normal distribution of δ D values, and a negative correlation between their δ 13C and δ D values, indicating an abiological origin. The present study has revealed that abiogenic hydrocarbons not only exist in nature but also can make significant contribution to commercial gas reserviors. It is estimated that the reserve volume of alkane gases with abiogenic characteristics in these 26 gas wells in the Songliao Basin is over 500×108 m3. The prospecting practice in the Songliao Basin has demonstrated that abiogenic alkane gases are of a promising resource, and it provides an example for the investigation of and search for abiogenic commercial natural gases worldwide. | WANG XianBin GUO ZhanQian TUO JinCai GUO HongYan LI ZhenXi ZHUO ShengGuang JIANG HongLiang ZENG LongWei ZHANG MingJie WANG LianSheng LIU ChunXue YAN Hong LI LiWu ZHOU XiaoFeng WANG YongLi YANG Hui WANG Guang | 2009 | Science China Earth Sciences2009，52，2： | 6 |
| 4 | The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury显示文摘Sentrin-specific protease 3(SENP3), a member of the desumoylating enzyme family, is known as a redox sensor and could regulate multiple cellular signaling pathways. However, its implication in myocardial ischemia reperfusion(MIR) injury is unclear. Here, we observed that SENP3 was expressed and upregulated in the mouse heart depending on reactive oxygen species(ROS) production in response to MIR injury. By utilizing si RNA-mediated cardiac specific gene silencing, SENP3 knockdown was demonstrated to significantly reduce MIR-induced infarct size and improve cardiac function. Mechanistic studies indicated that SENP3 silencing ameliorated myocardial apoptosis mainly via suppression of endoplasmic reticulum(ER) stress and mitochondrial-mediated apoptosis pathways. By contrast, adenovirusmediated cardiac SENP3 overexpression significantly exaggerated MIR injury. Further molecular analysis revealed that SENP3 promoted mitochondrial translocation of dynamin-related protein 1(Drp1) in reperfused myocardium. In addition, mitochondrial division inhibitor-1(Mdivi-1), a pharmacological inhibitor of Drp1, significantly attenuated the exaggerated mitochondrial abnormality and cardiac injury by SENP3 overexpression after MIR injury. Taken together, we provide the first direct evidence that SENP3 upregulation pivotally contributes to MIR injury in a Drp1-dependent manner, and suggest that SENP3 suppression may hold therapeutic promise for constraining MIR injury. | Lingchen Gao Yichao Zhao Jie He Yang Yan Longwei Xu Nan Lin Qingqi Ji Renyang Tong Yanan Fu Yu Gao Yuanyuan Su Ancai Yuan Ben He Jun Pu | 2018 | Journal of Genetics and Genomics2018，45，3： | 5 |
| 5 | RF front-end for digital beam position monitor signal processor显示文摘RF circuit board has a significant impact on performance of the Digital Beam Position Monitor (DBPM) in storage ring of a synchrotron radiation facility.In this paper,a front-end RF board is designed for DBPM,and schematics of the RF board and the test results are given.In view of the inevitable inconsistency in the multi-channel circuit,a calibration circuit is designed to reduce such an influence.The test results show that the calibration method is useful for beam current dependence which is sensitive to channels inconsistency. | YI Xing LENG Yongbin LAI Longwei ZHANG Ning YANG Guisen | 2011 | Nuclear Science and Techniques2011，22，2： | 4 |
| 6 | CsPb(I_(x)Br_(1-x))_(3) solar cells显示文摘Owing to its nice performance, low cost, and simple solution-processing, organic-inorganic hybrid perovskite solar cell(PSC) becomes a promising candidate for next-generation high-efficiency solar cells.The power conversion efficiency(PCE) has boosted from 3.8% to 25.2% over the past ten years. Despite the rapid progress in PCE, the device stability is a key issue that impedes the commercialization of PSCs. Recently, all-inorganic cesium lead halide perovskites have attracted much attention due to their better stability compared with their organic-inorganic counterpart. In this progress report, we summarize the properties of CsPb(IxBr1-x)3 and their applications in solar cells. The current challenges and corresponding solutions are discussed. Finally, we share our perspectives on CsPb(IxBr1-x)3 solar cells and outline possible directions to further improve the device performance. | Xue Jia Chuantian Zuo Shuxia Tao Kuan Sun Yixin Zhao Shangfeng Yang Ming Cheng Mingkui Wang Yongbo Yuan Junliang Yang Feng Gao Guichuan Xing Zhanhua Wei Lijun Zhang Hin-Lap Yip Mingzhen Liu Qing Shen Longwei Yin Liyuan Han Shengzhong Liu Lianzhou Wang Jingshan Luo Hairen Tan Zhiwen Jin Liming Ding | 2019 | Science Bulletin2019，64，20： | 2 |
| 7 | Effects of fish meal replacement with Chlorella meal on growth performance,pigmentation,and liver health of largemouth bass(Micropterus salmoides)显示文摘Chlorella meal is a potential protein source for aquafeeds.However,the physiological response of carnivorous fish fed Chlorella meal remains elusive.This study evaluated the effects of replacing dietary fish meal with Chlorella meal on growth performance,pigmentation,and liver health in largemouth bass.Five diets were formulated to replace dietary fish meal of 0%(C0,control),25%(C25),50%(C50),75%(C75),and 100%(C100)with Chlorella meal,respectively.Total 300 fish(17.6±0.03 g)were randomly assigned to 15 tanks(3 tanks/group).Fish were fed the experimental diet twice daily for 8 weeks.The increased dietary Chlorella meal quadratically influenced the final body weight(FBW),weight gain rate(WGR),specific growth rate(SGR),and feed intake(FI),which were significantly lower in the C100 group than in the other groups(P<0.05).The feed conversion ratio(FCR)increased linearly or quadratically with dietary Chlorella meal.Dietary Chlorella meal linearly or quadratically increased the lutein content of plasma,liver,and dorsal muscle of largemouth bass(P<0.05).Compared to the C0 group,all supplemented Chlorella meal groups significantly improved the yellowness(b*)of the dorsal body(1.5 to 2.0 fold),abdominal body(1.5 to 1.8 fold),and dorsal muscle(3.8 to 5.4 fold)of largemouth bass(P<0.05).In addition,compared to the C0 group,the liver vacuolation area of fish was significantly increased in the C75 and C100 groups(P<0.05).Transcriptional levels of apoptosis-related genes of b-cell lymphoma-2(bcl2),caspase-9-like(casp9),and caspase-3a(casp3)were markedly upregulated(0.9 to 1.6 fold)in the C100 group compared to the C0 group(P<0.05).Based on the quadratic regression analysis between FBW,WGR,or SGR and dietary Chlorella meal level,largemouth bass had the best growth when replacing 31.7%to 32.6%of fish meal with 15.03%to 15.43%dietary Chlorella meal.The present results indicated that dietary supplementation with Chlorella meal(11.85%to 47.45%)significantly enhanced the pigmentation;however,total replacement of fish meal(40%)with Chlorella meal(47.45%)caused growth retardation,apoptosis,and liver damage in largemouth bass. | Longwei Xi Qisheng Lu Yulong Liu Jingzhi Su Wen Chen Yulong Gong Dong Han Yunxia Yang Zhimin Zhang Junyan Jin Haokun Liu Xiaoming Zhu Shouqi Xie | 2022 | Animal Nutrition2022，，3： | 2 |
| 8 | Measurements of Wind Loads on Side-by-Side Semi-Submersibles in A Wind Tunnel显示文摘The multi-body system has been a popular form for offshore operations in terms of high efficiency.The wind effects are crucial which directly affect the relative positions of floating bodies and operating security.In this study,the aerodynamic characteristics for two coupled semi-submersibles were analyzed in a wind tunnel to fill the gaps in literature related to the wind sheltering on offshore platforms.The influences of separation distance were also investigated.According to the results,substantial shielding effects were observed and wind forces on the shielded vessel decreased dramatically:a reduction in the transverse force could be up to 74%.Moreover,the longitudinal wind load was amplified by the platform abreast in a side-by-side configuration.As expected,the interference level became more pronounced with a decreasing separation distance.For cases in which wind interaction decayed rapidly with distance,logarithmic functions were preferable for describing the relationship between them.Whereas linear fitting was reasonable for the transverse wind force when there was still evident sheltering at a quite large distance.The length of shielding area was another important factor that there was approximately a linear relationship between it and the shielding level for two platforms in close proximity at various wind attack angles.Based on the two parameters,a preliminary wind loads estimation method considering shielding effects was proposed.This approach can aid the industry to have a qualitative assessment of wind sheltering especially at early stages. | DONG Qing GUO Xiao-xian YANG Jian-min LU Hai-ning HUANG Longwei | 2021 | China Ocean Engineering2021，35，4： | 1 |
| 9 | A high-performance potassium-ion capacitor based on a porous carbon cathode originated from the Aldol reaction product显示文摘Potassium-ion capacitors(KICs) emerge as a promising substitute for the well-developed lithium-ion capacitors(LICs),however,the energy density of KICs is below expectations because of lacking a suitable electrical double-layer positive electrode.Using chemical activation of the Aldol reaction product of acetone with KOH,we synthesized a porous ca rbon with a Brunauer-Emmett-Teller surface area of up to 2947 m2/g and a narrow pore size distribution ranging from 1 nm to 3 nm.Half-cell(versus potassium metal) test demonstrates that this porous carbon has high capacitive performance in K+ based organic electrolytes.Furthermore,a novel KIC fabricated by this porous carbon as the cathode,yields high values of energy density and power density.The processes used to make this porous carbon are readily low-cost to fabricate metal-ion capacitors. | Xu Yu Mingjie Shao Xuemei Yang Chongxing Li Tong Li Danyu Li Rutao Wang Longwei Yin | 2020 | Chinese Chemical Letters2020，31，9： | 1 |
| 10 | QTL underlying iron and zinc toxicity tolerances at seedling stage revealed by two sets of reciprocal introgression populations of rice(Oryza sativa L.)显示文摘Iron and zinc are two trace elements that are essential for rice. But they are toxic at higher concentrations, leading to severe rice yield losses especially in acid soils and inland valleys. In this study, two reciprocal introgression line(IL) populations sharing the same parents were used with high-density SNP bin markers to identify QTL tolerant to iron and zinc toxicities. The results indicated that the japonica variety 02,428 had stronger tolerance to iron and zinc toxicities than the indica variety Minghui 63. Nine and ten QTL contributing to iron and zinc toxicity tolerances,respectively, were identified in the two IL populations. The favorable alleles of most QTL came from 02,428. Among them, q FRRDW2, q ZRRDW3, and q FRSDW11 appeared to be independent of genetic background. The region C11S49–C11S60 on chromosome 11 harbored QTL affecting multiple iron and zinc toxicity tolerance-related traits, indicating partial genetic overlap between the two toxicity tolerances. Our results provide essential information and materials for developing excellent rice cultivars with iron and/or zinc tolerance by marker-assisted selection(MAS). | Huan Liu Aijaz Soomro Yajun Zhu Xianjin Qiu Kai Chen Tianqing Zheng Longwei Yang Danying Xing Jianlong Xu | 2016 | The Crop Journal2016，4，4： | 1 |
| 11 | Reservoir Quality and Diagenesis of the Permian Lucaogou Formation Tight Carbonates in Jimsar Sag, Junggar Basin, West China显示文摘The Lower Permian Lucaogou Formation in the Jimsar sag, Junggar Basin is a typical tight-oil reservoir in China. For effective exploration and production, the formation of a high-quality reservoir must be thoroughly studied. In this work, the tight-oil reservoir was examined using a variety of methods, including core and thin-section observations, XRD, SEM, CL and fluid inclusion and isotope testing. The tight-oil reservoirs were primarily deposited in saline lake environments, which are dominated by variable admixture of dolomite, quartz, feldspar, tuff, calcite and pyrite. Nine main lithofacies were identified:(1) siliceous mudstone,(2) dolomitic siliceous mudstone,(3) dolomitic mudstone,(4) intraclast packstone/grainstone,(5) ooid grainstone,(6) bioclast grainstone,(7) dolomitic siltstone,(8) mixed siliclastic and intraclast grainstone and(9) brecciated dolomitic mudstone. The pore types are classified into four categories: primary intergranular, moldic, intercrystalline and fracture pores. The properties of tight-oil reservoirs are quite poor, with low porosity(ave. 7.85%) and permeability(ave. 0.110 mD) and a small pore-throat radius(ave. 0.086 μm). The tight-oil reservoirs are dominated by the aggradation of a repetitive meter-scale sedimentary facies succession that records distinct lacustrine expansions and contractions. These tight carbonates have also undergone significant diagenetic alterations, such as dolomitization, dissolution, neomorphism and fracture created intercrystalline and moldic pores, vug and fractures; chemical and mechanical compaction and carbonate cementation have decreased the reservoir quality. Variations in reservoir quality in the Jimusar sag are due to a combination of lithofacies type, high-frequency cyclic depositional architecture, dissolution intensity, dolomitization and tectonic related deformation. This integrated study has helped in understanding the reservoir heterogeneity and hydrocarbon potential of the Jimusar fine-grained rocks. | Yongqiang Yang Longwei Qiu Yingchang Cao Cheng Chen Dewen Lei Ming Wan | 2017 | Journal of Earth Science2017，28，6： | 1 |
| 12 | A Comprehensive Porosity Prediction Model for the Upper Paleozoic Tight Sandstone Reservoir in the Daniudi Gas Field, Ordos Basin显示文摘This paper investigated the porosity controlling factors for tight sandstone reservoir in the Daniudi gas field, Ordos Basin based on an integrated petrographic, petrophysical and geostatistical analyses, and proposed a comprehensive prediction model for reservoir porosity. Compaction was found to be a key factor for causing reservoir densification. The degree of sandstone compaction appears to be affected by grain sizes and sorting. Under normal compaction conditions(e.g., cement content less than 6%, and with no dissolution), the variation in reservoir porosity with burial depth can be well correlated with grain compositions, grain sizes, and sorting. Based on qualitative examination of the controlling factors for reservoir porosities, geostatistics were used to quantify the effects of various geological parameters on reservoir porosities. A statistical model for comprehensive prediction of porosity was then established, on the assumption that the present reservoir porosity directly relates to both normal compaction and diagenesis. This model is easy to use, and has been validated with measured porosity data. The porosity controlling factors and the comprehensive porosity prediction can be used to quantify effects of the main controlling factors and their interaction on reservoir property evolution, and may provide a reference model for log interpretation. | Longwei Qiu Shengchao Yang Changsheng Qu Ningning Xu Qingsong Gao Xiangjin Zhang Xugang Liu Donghui Wang | 2017 | Journal of Earth Science2017，28，6： | 1 |
| 13 | The effect of external network competence and intrafirm networks on a firm' s innovation performance : the moderating influence of relational governance 显示文摘 | Ren Shenggang Wang Longwei Yang Wei | 2013 | Innovation2013，15，1： | 1 |
| 14 | Back analysis of grouted rock bolt pullout strength parameters from field tests显示文摘 | Li Bin Qi Taiyue Zhengzheng Wang Yang Longwei | 2011 | Tunnelling and Underground Space Technology incorporating Trenchless Technology Research2011，，： | 1 |
| 15 | DLX5 promotes Col10a1 expression and chondrocyte hypertrophy and is involved in osteoarthritis progression显示文摘Osteoarthritis(OA)has been considered non-reversible as articular cartilage wears down with limited repair capacity.Enhanced chondrocyte hypertrophy and increased type X collagen gene(COL10A1)expression have been associated with OA.Therefore,regulators controlling collagen X expression and chondrocyte hypertrophy may play a role in OA intervention.Here,we investigated how Distal-less homeobox 5(DLX5),the distal-less homeobox family member,controls murine Col10a1 gene expression and chondrocyte hypertrophy in chondrogenic cell models and its role in a murine OA model.Through qRT-PCR and Western blot analyses,we detected significantly increased levels of COL10A1 and DLX5 in hypertrophic MCT and ATDC5 cells compared to their proliferative stage.Forced expression of Dlx5 further increases,while knockdown of Dlx5 decreases COL10A1 expression in hypertrophic MCT cells.We have performed dual-luciferase reporter and ChiP assays and demonstrated that DLX5 promotes reporter activity through direct interaction with Col10a1 cis-enhancer.We established a murine OA model and detected markedly increased COL10A1 and DLX5 in the articular cartilage and subchondral bone of the OA mice compared with the controls.Notably,forced overexpression of DLX5 in hypertrophic MCT cells up-regulates RUNX2,and adjacent DLX5 and RUNX2 binding sites have previously been found within the Col10a1 cis-enhancer.Together,our data suggest that DLX5 may cooperate with RUNX2 to control cell-specific Col10a1 expression and chondrocyte hypertrophy and is involved in OA pathogenesis. | Jinnan Chen Fangzhou Chen Xuan Wu Huiqin Bian Chen Chen Xiaojing Zhang Ruoxuan Hei Xiaotong Yang Haochun Yuan Qian Wang Yaojuan Lu Longwei Qiao Qiping Zheng | 2023 | Genes & Diseases2023，10，5： | 1 |
| 16 | Solid-state template-free fabrication of uniform Mo2C microflowers with lithium storage towards Li-ion batteries显示文摘Herein,we first report one-step synthesis of uniform Mo2 C microflowers(MCMFs)from low-cost precursors via industrialized solid-state strategy.With fine optimization in precursor ratio and pyrolysis temperatures,the as-fabricated MCMFs are assembled well with interconnected single-crystalline nanosheet subunits.More encouragingly,the resultant MCMFs are further highlighted as a competitive anode with robust and long-duration lithium-storage behaviors towards high-performance Li-ion batteries. | Jinfeng Sun Lingzhi Guo Miaomiao Gao Xuan Sun Jinyang Zhang Longwei Liang Yang Liu Linrui Hou Changzhou Yuan | 2020 | Chinese Chemical Letters2020，31，6： | 0 |
| 17 | Integrated Rabies Surveillance-Hunan Province,China,2020显示文摘Introduction:The objective of this paper was to assess the epidemiology of rabies in Hunan Province,analyze the associated factors,understand the status of prevention and treatment after rabies exposure,evaluate the effectiveness of prevention and treatment,and provide a scientific basis for formulating effective prevention and control measures.Methods:The surveillance data of rabies in Hunan Province in 2020 were collected and analyzed by descriptive epidemiological method.Results:In 2020,a total of 59 cases of rabies were reported in Hunan Province,with an incidence rate of 0.09/100,000.Overall,42 cases(71.19%)were due to animal bites and 43 cases(72.88%)were of grade III.The proportion of hand and combined injury of hand was the highest(40.68%).A total of 603,261 cases of rabies exposure were reported from the rabies post-exposure prophylaxis(PEP)clinic in Hunan Province.Dogs were the main animal causing injuries,accounting for 74.21%.Only 83,418(13.84%)of the animals had a clear immune history,and a total of 11 dog attacks were reported in Hunan Province.The average immunity rate of dogs in the whole province was 30.98%.In 2020,554 dogs were sampled in the whole province;20 of them were positive for a positivity rate of 3.61%.Conclusions:Rabies in Hunan Province in 2020 had a relatively low prevalence.Failure to treat wounds,immunoglobulin injections,and vaccination after exposure were the main causes of rabies.Therefore,post-exposure management of rabies should be further strengthened to reduce the risk of rabies for high-risk populations. | Hao Yang Shengbao Chen Zhihui Dai Longwei Luo Qianlai Sun Shanlu Zhao Ge Zeng Ziyan Liu Shixiong Hu | 2022 | China CDC weekly2022，4，44： | 0 |
| 18 | Characterization of mesenchymal stem cells in human fetal bone marrow by single-cell transcriptomic and functional analysis显示文摘Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma,cartilage, fat, and bone. Although a significant progress has been made toward recognizing about the phenotypic characteristics ofMSCs, the true identity and properties of MSCs in bone marrow remain unclear. Here, we report the expression landscape of humanfetal BM nucleated cells (BMNCs) based on the single-cell transcriptomic analysis. Unexpectedly, while the common cell surfacemarkers such as CD146, CD271, and PDGFRa used for isolating MSCs were not detected, LIFR+PDGFRB+ were identified to bespecific markers of MSCs as the early progenitors. In vivo transplantation demonstrated that LIFR+PDGFRB+CD45-CD31-CD235a-MSCs could form bone tissues and reconstitute the hematopoietic microenvironment (HME) effectively in vivo. Interestingly, wealso identified a subpopulation of bone unipotent progenitor expressing TM4SF1+CD44+CD73+CD45-CD31-CD235a-, which hadosteogenic potentials, but could not reconstitute HME. MSCs expressed a set of different transcription factors at the different stagesof human fetal bone marrow, indicating that the stemness properties of MSCs might change during development. Moreover,transcriptional characteristics of cultured MSCs were significantly changed compared with freshly isolated primary MSCs. Ourcellular profiling provides a general landscape of heterogeneity, development, hierarchy, microenvironment of the human fetal BMderivedstem cells at single-cell resolution. | Ping Zhang Ji Dong Xiaoying Fan Jun Yong Ming Yang Yunsong Liu Xiao Zhang Longwei Lv Lu Wen Jie Qiao Fuchou Tang Yongsheng Zhou | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 0 |
| 19 | Sedimentary Processes and Depositional Characteristics of Coarse-grained Subaqueous Fans along Steep Slopes in a Lacustrine Rift Basin:A Case Study from the Dongying Depression,Bohai Bay Basin,China显示文摘Coarse-grained subaqueous fans are vital oil and gas exploration targets in the Bohai Bay basin,China.The insufficient understanding of their sedimentary processes,depositional patterns,and controlling factors restricts efficient exploration and development.Coarse-grained subaqueous fans in the Yong′an area,Dongying Depression,are investigated in this study.These fans include nearshore subaqueous fans,and sublacustrine fans,and their sedimentary processes,depositional patterns and distribution characteristics are mainly controlled by tectonic activity and paleogeomorphology.Nearshore subaqueous fans developed near the boundary fault during the early–middle deposition stage due to strong tectonic activity and large topographic subsidence.Early sublacustrine fans developed at the front of the nearshore subaqueous fans in the area where the topography changed from gentle to steep along the source direction.While the topography was gentle,sublacustrine fans did not develop.During the late weak tectonic activity stage,late sublacustrine fans developed with multiple stages superimposed.Frequent fault activity and related earthquakes steepened the basin margin,and the boundary fault slopes were 25.9°–34°.During the early–middle deposition stage,hyperpycnal flows triggered by outburst floods developed.During the late deposition stage,with weak tectonic activity,seasonal floods triggered hyperpycnal flows,and hybrid event beds developed distally. | YANG Baoliang QIU Longwei YANG Yongqiang Kouassi Louis KRA DONG Daotao Danish KHAN | 2023 | Acta Geologica Sinica(English Edition)2023，97，2： | 0 |
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